Best Semaglutide for Women in 2026: Ranked and Reviewed

Dosing does not change by sex, and the pivotal trials enrolled both women and men (STEP-1 averaged around 15% body-weight loss), so the seller table below is the same one we publish for everyone. What changes is the list of things to settle first. The semaglutide labels say to come off it when a pregnancy is confirmed, and two months or more ahead of a planned one. Delayed gastric emptying can affect how an oral contraceptive is absorbed. Cycles shift for some women during rapid loss, thyroid and PCOS histories complicate the picture, and hair shedding is common enough to plan for. Those belong in a conversation with a prescriber rather than in a comparison table.

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By Ruth Calder · Enforcement Editor
Editorially reviewed. Not medical advice · How we verify contentLast reviewed

619 semaglutide providers compared · independently scored against our six-factor methodology.

Price and states served both move. Read them off the seller's own site before you enroll.How our reviews work →

Methodology & sources

Each provider here carries a score from our published six-factor rubric[1], and the list is then cut down to the criteria named in the page title.

Published Phase 3 efficacy for semaglutide 2.4 mg (~14.9% mean weight loss over 68 weeks) comes from the STEP 1 trial[2]. The SURMOUNT-5 head-to-head published in 2025 directly compared tirzepatide and semaglutide[3].

Quick Picks

Starting price per provider. Prices in USD per month; checked November 2026.
#ProviderScore
1EmbodyVisit
2SnagRxVisit
3CollectiveVisit
4CoreAge RxVisit
5LttlVisit

What the trials show for women

These are the women-specific figures our research desk has already checked against the trials and the Wegovy label. Each links to the article that reports it in full.

  • 10.9% vs 6.8%

    average weight lost, women vs men

    In the six trials that reported weight loss by sex, covering 19,906 people, women lost 10.9% of body weight on average and men 6.8%. Part of the gap is arithmetic, since the same kilograms are a larger share of a lighter body.[4]

    Who loses more weight →
  • 4% vs 0.9%

    hair loss on Wegovy 2.4 mg, women vs men

    Hair loss is the widest sex gap on the Wegovy label: 4% of women on the 2.4 mg dose reported it, against 0.9% of men. The label ties it to weight reduction.[5]

    Side effects by sex →
  • Same blood level

    and women still reported more nausea

    Body size explains only part of the nausea gap. In a pooled analysis of four semaglutide diabetes trials (1,552 adults), women reported nausea more often than men at every blood level of the drug. Raising the dose slowly blunted the extra nausea.[6]

  • 2 months

    off semaglutide before a planned pregnancy

    Wegovy's label sets a gap of two months or more between the last dose and trying to conceive, a period it ties to how slowly semaglutide clears. Plan that timeline backwards from when you want to try.[5]

    Preconception timing, drug by drug →

Detailed Reviews

1

Embody

Verified partner

Best for: a flat compounded tirzepatide or semaglutide price at every dose, from a seller that names its pharmacies

9.3

Embody is the brand Modern Metabolic Medicine, Inc. runs through its JoinEm storefront. It sells compounded semaglutide and tirzepatide injections at one price per drug at every dose, $79 and $129 for a one-month supply, plus a compounded oral tirzepatide gum. You pay at checkout, before an OpenLoop Health clinician decides on a prescription, and payments are final.

Score Breakdown

Value25%
10
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
9
Accessibility10%
10
Support10%
7
2

SnagRx

Verified partner

Best for: semaglutide at $99/month, well below the typical price

9.2

SnagRx sells compounded semaglutide at $99 a month and compounded tirzepatide at $149 a month on its 1-month plan, one price at every dose. Longer plans cut the monthly rate but are charged in full up front and are non-refundable. Clinicians come from the OpenLoop Health network; the platform is Modern Metabolic Medicine, Inc. The visit and 1-2 day shipping are included, with no insurance and no membership.

Score Breakdown

Value25%
10
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
9
Accessibility10%
9.8
Support10%
7
3

Collective

Verified partner

Best for: flat any-dose pricing, if you can absorb a $199 annual membership on top

9.1

Health For Everyone Inc., trading as CollectiveOS, sells compounded semaglutide at $59/mo and compounded tirzepatide at $69/mo on a membership model, with a mandatory $199 annual membership on top that the headline price does not include. It prices every dose the same, so the cost does not climb as the dose is titrated, and it does not require prepaying for medication. The site is marketed as being from the founder of Thrive Market. Neither its pharmacies nor its medical groups are named.

Score Breakdown

Value25%
10
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
9
Accessibility10%
9
Support10%
7
4

CoreAge Rx

Verified partner

Best for: flat-priced compounded semaglutide at $79 a month, any dose

9.0

CoreAge Rx charges the same amount at every dose of its compounded GLP-1s: semaglutide is $79 a month, tirzepatide $129. Consult and shipping are inside that figure, and there is no membership fee. You pay before a doctor reviews the case, and every prescription sale is final once it reaches the pharmacy.

Score Breakdown

Value25%
10
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
7.5
Accessibility10%
9.7
Support10%
7
5

Lttl

Verified partner

Best for: starting below a standard dose, with microdose tiers

9.0

Lttl sells compounded semaglutide at $99 a month and tirzepatide at $149 a month on its month-to-month plan, one flat price at any dose. Prepaying for 12 months lowers those to $89 and $139. Every price and commitment length is on a public plans page before checkout. A microdose line at $149 a month and longevity peptides fill out the catalog.

Score Breakdown

Value25%
10
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
7.5
Accessibility10%
10
Support10%
7
6

YourEra

Verified partner

Best for: semaglutide at $99/month, well below the typical price

9.0

YourEra sells compounded semaglutide and compounded tirzepatide injections through an online visit with a licensed clinician, at one price for every dose. It is run by Your Era Management, L.L.C. in Louisiana, and it names its medical group and its three pharmacies. Semaglutide is $99 a month month-to-month. Tirzepatide is published only as a 12-month prepaid plan averaging $99 a month.

Score Breakdown

Value25%
10
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
7.5
Accessibility10%
10
Support10%
7
7

altRX

Verified partner

Best for: compounded semaglutide from $89/month at the same price at every dose

8.8

Compounded plans open at $89 for semaglutide and $149 for tirzepatide, the same at every dose. Branded medication runs $1,149-$1,579, a figure that already contains the consult and the shipping. Every one of the four FDA-approved brands is stocked, Mounjaro, Ozempic, Wegovy and Zepbound, which no other entry in our directory matches. altRX works in both modalities, holds LegitScript certification, and prints the FDA compounded-medication disclaimer. FDA sent its operator a warning letter in June 2026.

Score Breakdown

Value25%
10
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
6
Accessibility10%
10
Support10%
7
8

Eden

Verified partner

Best for: coverage in all 50 states, which most sellers will not confirm

8.7

Eden sells compounded semaglutide and tirzepatide through its own pharmacy network and a contracted provider group. Its price pages promise the same charge at every dose and say there is no membership fee. Its own terms still describe a $39-then-$99 monthly membership with medication billed on top. Semaglutide is $99 a month and tirzepatide $129.

Score Breakdown

Value25%
10
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
4.5
Accessibility10%
10
Support10%
8.5
9

Strut Health

Verified partner

Best for: semaglutide at $99/month, well below the typical price

8.6

Strut Health sells LegitScript and ACHC-accredited compounded semaglutide and tirzepatide in injectable and oral lozenge formats, shipping to 49 states. Board-certified US physicians handle prescribing and follow-up messaging is unlimited and free. Eligibility is gated behind a clinician determination of medical necessity that the company does not publicly define.

Score Breakdown

Value25%
10
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
4.5
Accessibility10%
9.8
Support10%
7
10

Gala

Verified partner

Best for: moving between compounded and brand without changing seller

8.5

A yearly plan is the format: compounded semaglutide and compounded tirzepatide are sold that way, with brand-name Ozempic on the same menu. The corporate name is AI Coaching Inc., which does business as Gala GLP-1 and is incorporated in Delaware; care comes through OpenLoop-affiliated medical groups. Compounded GLP-1 is $179 a month on the yearly plan, all doses included. A Wegovy pill taken orally is flagged as coming soon.

Score Breakdown

Value25%
7.9
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
7.5
Accessibility10%
10
Support10%
7

Ranked 11 to 30

The same ranking continues in short form: each seller's score, the lowest standing price we hold, and a link to its full review.

  1. 11
    bmiMDVerified partner

    From $129/mo

    8.2
  2. 12
    HealthRXVerified partner

    From $165/mo

    8.2
  3. 13
    Live VitalVerified partner

    From $130/mo

    8.2
  4. 14
    Sesame CareVerified partner

    From $149/mo

    8.1
  5. 15
    PlexusDxVerified partner

    From $99/mo

    8.0
  6. 16
    Sprout HealthVerified partner

    From $99/mo

    8.0
  7. 17
    Belle HealthVerified partner

    From $199/mo

    7.9
  8. 18
    Luvo HealthVerified partner

    From $179/mo

    7.9
  9. 19
    RxSpan MDVerified partner

    From $249/mo

    7.9
  10. 20
    ShedRxVerified partner

    From $149/mo

    7.9
  11. 21
    AgelessRxVerified partner

    From $99/mo

    7.4
  12. 22
    WellorithmVerified partner

    From $247/mo

    7.4
  13. 23
    FoundVerified partner

    From $199/mo

    7.3
  14. 24
    Ivim HealthVerified partner

    From $140/mo

    7.3
  15. 25
    MEDGmVerified partner

    From $169/mo

    7.3
  16. 26
    OakVerified partner

    From $100/mo

    7.2
  17. 27
    Direct MedsVerified partner

    From $249/mo

    7.1
  18. 28
    DudeMedsVerified partner

    From $175/mo

    6.8
  19. 29
    GoodLife HealthVerified partner

    From —

    6.8
  20. 30
    HumeCare+Verified partner

    From $199/mo

    6.6

589 more sellers we track for this

Ranked below the 30 above on the same rubric. Each links to its full review with current pricing.

We rank the list above the same way for every reader. What differs for women is the clinical context, and these evidence reviews go into it:

Frequently Asked Questions

Not in dosing: no label sets a different dose by sex. In the results, yes, a little. Across the trials that reported weight loss by sex, women lost a larger share of body weight than men, and on the labels women report hair loss more often. Nausea during dose increases is also more common in women. None of that is a reason to avoid the drug. All of it is a reason to raise the subject with a prescriber before you start.
Taken for weight, Wegovy is to be stopped when a pregnancy is confirmed, and the semaglutide labels want two months or more without the drug ahead of a planned pregnancy, because semaglutide is slow to clear. Use reliable contraception while you are on it, and tell your prescriber where family planning sits for you.
It can, though neither effect has been precisely measured. Rapid weight loss and the medication itself shift cycle patterns for some women. Delayed gastric emptying is a theoretical route to reduced absorption of oral medications, which is why some prescribers suggest a backup or non-oral contraceptive method through dose escalation. Ask yours directly instead of assuming either way.
Sources & methodology — as of November 2026
  1. 1.GLP Watchdog — GLP-1 Pricing Index 2026 (our independent dataset)— GLP Watchdog.
  2. 2.STEP 1 Trial — Once-Weekly Semaglutide in Adults with Overweight or Obesity (Wilding JPH et al.)— New England Journal of Medicine.PMID: 33567185.
  3. 3.SURMOUNT-5 Trial — Tirzepatide vs. Semaglutide Head-to-Head in Obesity (Aronne LJ et al.)— New England Journal of Medicine.PMID: 40353578.
  4. 4.Heterogeneity of Treatment Effects of GLP-1 Receptor Agonists for Weight Loss in Adults: A Systematic Review and Meta-Analysis (Alexander GC et al.)— JAMA Internal Medicine.PMID: 41770554.
  5. 5.Wegovy (semaglutide) prescribing information, DailyMed SPL— Novo Nordisk, via the National Library of Medicine (DailyMed).
  6. 6.Exposure-response analysis for evaluation of semaglutide dose levels in type 2 diabetes (Petri KCC et al.)— Diabetes, Obesity and Metabolism.PMID: 29748996.