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PlexusDx Review

Semaglutide & tirzepatide GLP-1 weight-loss telehealth · Independently scored 8/10

Best for: one compounded GLP-1 price at every dose, as an injection or a tablet, from a named pharmacy

8.0
★★★★☆8.0/10

PlexusDx scores highest on the clinical side (which drugs it prescribes and how it doses) and lowest on availability. It charges from $99 a month; its compounded tirzepatide, at $189, is 30% below the $269 median among the sellers we compare.

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$99/mo

microdose tier; standard plans start at $149/mo

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Not stated

Coaching

Not stated

See plans →

Prices checked October 2026

PlexusDx sells compounded semaglutide at $149 a month and compounded tirzepatide at $189, as weekly injections or daily tablets, plus a microdose GLP-1 plan at $99. One price covers the visit, drug and shipping, and it does not rise with the dose; prepaying a year cuts the rate to $99 and $129. Lone Star Virtual Health prescribes and Vials RX in Texas fills. An optional genetic test is $99 after the first month.

By Ruth Calder · Enforcement Editor
Editorially reviewed. Not medical advice · How we verify contentLast reviewed
GLP-1 from $99/moPrice shown up frontFlat across dosesIncludes medication + consultPharmacy namedNo FDA warning letters found

Is PlexusDx legit?

Yes. PlexusDx is a real, operating US company, and we found no FDA warning letters issued to it. We rate it 8.0/10 overall, across six areas from price to trust and safety. Legitimate is not the same as right for you, though: that part is a decision for you and a licensed clinician.

Is there a PlexusDx promo or coupon code?

We know of no promo or coupon code for PlexusDx. Its listed price is $99 a month. Coupon sites advertising "PlexusDx discount codes" are not a source we can vouch for, and any genuine offer shows at checkout without a code.

See how PlexusDx compares on our rankings of the best semaglutide providers and the best tirzepatide providers.

PlexusDx logo
8.0 / 10
Our editorial rating
Visit PlexusDx →

from $99/mo · no insurance needed

PlexusDx at a glance

Type
GLP-1 telehealth provider
Medications
Compounded semaglutide, Compounded tirzepatide
Starting price
$99/mo
Pricing model
Flat: the price stays the same as the dose goes up
What's included
Medication · Consult · Shipping
FDA status
No FDA warning letters found

How PlexusDx scores

Six columns, each one computed from something PlexusDx has published rather than from an opinion we formed: what it charges, which molecules it will dispense, what its record shows, and what the monthly figure actually buys. Where a seller keeps something back, such as its price or its pharmacy, the score reflects it. Every seller we review goes through the same six columns.

Value25%

7.5/10

$189/month is 30% below the $269 median for compounded tirzepatide across the sellers we compare.

Effectiveness25%

10.0/10

Dispenses semaglutide and tirzepatide, compounded only. Anchored to SURMOUNT-1 (tirzepatide, -20.9%) and STEP 1 (semaglutide, -14.9%).

User Experience15%

8.0/10

A price is shown before the questionnaire starts.

Trust & Safety15%

8.0/10

It names the pharmacy that fills its prescriptions. It shows a price before asking for health information.

Accessibility10%

5.0/10

No state list is available to check, so this is held at the midpoint rather than scored on reach.

Support10%

7.0/10

The price covers the medication, clinician visits and shipping.

6weighted dimensions
734sellers compared
Everychecked against the seller's own site
Value 25%Effectiveness 25%User Experience 15%Trust & Safety 15%Accessibility 10%Support 10%

A seller that shows no price until after the medical intake loses points on User Experience and Trust & Safety, and its review says so. How we score →

What we checked on PlexusDx

Last checked October 2026
  • Checked the listed price across 5 dose or plan tiers
  • Checked what the monthly price covers, and what it leaves out
  • Recorded which pharmacies the seller names as filling its prescriptions, with the page and date
  • Checked FDA warning letters for PlexusDx

Price, availability, and compliance here are read off the seller's own pages and off primary regulatory records, named in the sources below.

What signing up with PlexusDx involves

What to expect on the way to a prescription: where the price appears, who fills the medication, and what the monthly price covers. It is not medical advice, and a clinician makes the prescribing decision.

  1. 1PlexusDx shows a price on its own site before asking anything about you, so you can compare it with other sellers before you start a questionnaire.
  2. 2Vials RX fills the prescriptions, and PlexusDx names it publicly, which most sellers do not.
  3. 3The monthly price includes the medication, clinician visits and shipping.
Price shown before you start
  • Lowest ongoing monthly price: semaglutide $149, tirzepatide $189. That leaves out membership fees, first-month rates and insurance copays.
  • Confirm that PlexusDx serves your state before you start.
  • The medication is compounded, so it is not an FDA-approved product and has not been reviewed by the agency for safety, effectiveness or manufacturing quality.

Cancelling PlexusDx

Taken from the terms PlexusDx publishes. Terms change, so check the current policy before you subscribe.

Cancel any time
Yes
Minimum commitment
Monthly by default; longer terms are prepaid and auto-renew for the same length
Refund policy
Full refund if the prescription has not yet gone to the pharmacy; no refund once it has, and no prorated refund of a prepaid term
Early-termination fee
None

Medications PlexusDx lists

PlexusDx lists compounded semaglutide and compounded tirzepatide. Each one has its own guide: how it works, the dosing schedule, the side effects that show up in practice, and what the trials measured.

Peptides PlexusDx offers

PlexusDx sells peptides beyond the GLP-1s. Tap one to read what the evidence says about it.

Pricing

Prices re-verified

Microdose GLP-1, month to monthCompounded
$99/mo

Semaglutide or tirzepatide, tablet or injection. 3 months $267 ($89 a month), 6 months $474 ($79), 12 months $828 ($69), each billed up front.

Injection, month to monthCompounded
$149/mo
semaglutide

Same price at every dose. 3 months $387 ($129 a month), 6 months $654 ($109), 12 months $1,188 ($99), each billed up front.

Daily oral tablet, month to monthCompounded
$149/mo
semaglutide

Same plan ladder as the injection: $129, $109 and $99 a month on 3, 6 and 12-month plans billed up front.

Injection, month to monthCompounded
$189/mo
tirzepatide

Same price at every dose. 3 months $507 ($169 a month), 6 months $894 ($149), 12 months $1,548 ($129), each billed up front.

Daily oral tablet, month to monthCompounded
$189/mo
tirzepatide

Same plan ladder as the injection: $169, $149 and $129 a month on 3, 6 and 12-month plans billed up front.

Check the price yourself before you pay

Every figure here comes from PlexusDx's own website, as of the date shown. Sellers move prices without announcing it, and promotional rates lapse, so confirm the standing cost on their site before committing.

See PlexusDx pricing →

PlexusDx compounding-pharmacy partners

PlexusDx names each pharmacy below as one that compounds or fills its prescriptions, in its own site, terms or filings. The quote under each one is the seller’s own wording.

Vials RX

“Our partner pharmacies include Vials RX (NI9 Health Group LLC), a compounding pharmacy in Tomball, Texas.”

Compare every compounding pharmacy we’ve reviewed →

In its favor

  • Semaglutide costs $149 a month, 25% below the $199 median for compounded semaglutide across the sellers we compare
  • Tirzepatide costs $189 a month, 30% below the $269 median for compounded tirzepatide across the sellers we compare
  • Shows its price before the medical questionnaire, so you can compare it without handing over health information
  • The monthly price stays the same as your dose goes up
  • The monthly price includes the medication, clinician visits and shipping
  • Names Vials RX as the pharmacy that fills its prescriptions, which most sellers do not
  • We found no FDA warning letters issued to PlexusDx

Against it

  • Confirm it serves your state before you start the intake
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

What PlexusDx charges

PlexusDx charges $99/month for its microdose tier; its standard plans start at $149/month and hold that rate across every dose.

  • Microdose GLP-1, month to month: $99/month
  • Compounded semaglutide (injection): $149/month
  • Compounded semaglutide (tablet): $149/month
  • Compounded tirzepatide (injection): $189/month
  • Compounded tirzepatide (tablet): $189/month

For compounded tirzepatide, the median across the sellers we compare is $269/month, so PlexusDx's $189 is genuinely below the middle, not just advertised that way. Before you pay, compare PlexusDx's cancellation terms with other sellers' cancellation and refund policies.

AgelessRx, at about $99/month, is the closest like-for-like alternative we review.

What PlexusDx dispenses

PlexusDx prescribes semaglutide (approved as Wegovy and Ozempic) and tirzepatide (approved as Zepbound and Mounjaro). Between them these are the pair carrying the strongest published outcome data. What arrives is compounded at a licensed pharmacy, not an approved pen. That is the reason it costs less, and the reason the finished preparation carries no FDA review behind it. The molecule can be the one in Ozempic and Wegovy; what differs is the formulation, the concentration and the dose ladder. PlexusDx also lists a microdose plan, and the published evidence on GLP-1 microdosing is letters and commentary rather than trials.

A needle-free oral option is genuinely uncommon and is the reason some readers will look at PlexusDx at all. Set expectations on the evidence, though: the published weight-loss trials for these molecules used injections. Oral and sublingual delivery of peptides is far less studied, so treat it as a route that solves the needle problem rather than as a proven equal to the shot.

Safety and disclosure

PlexusDx tells you its price before you start the medical questionnaire and the pharmacy that fills its prescriptions. We found no FDA warning letters issued to PlexusDx. Because the medication is compounded, the named pharmacy is the detail that matters most: its license is the one you can look up. The FDA's warning signs for online medicine sellers are a quick check to run on any seller before you pay. How we weigh oversight, disclosure and price is set out in our scoring methodology.

PlexusDx also sells NAD+, and a 2026 systematic review found no outcomes trials of injected NAD+ for anti-aging or wellness.

Who should look elsewhere

  • You want the FDA-approved pen specifically. Everything listed here is compounded.
  • You need insurance to cover the cost. Check whether PlexusDx bills your plan before you start.

It fits if

  • the lowest standing monthly cost is what you are solving for
  • you want the price to stop moving as your dose climbs
  • injections are the thing keeping you from starting

Our read

PlexusDx competes on price without an obvious sacrifice elsewhere: $189/month for compounded tirzepatide, no FDA warning letters.

The Bottom Line

PlexusDx scores highest on the clinical side (which drugs it prescribes and how it doses) and lowest on availability. It charges from $99 a month; its compounded tirzepatide, at $189, is 30% below the $269 median among the sellers we compare.

Score: 8/10Best for: one compounded GLP-1 price at every dose, as an injection or a tablet, from a named pharmacyFrom: $99/mo

Before you pay PlexusDx

Starting at $99 a month. Check today's price, then start the intake.

Where PlexusDx is the wrong choice

No seller suits every reader, and pretending otherwise is the easiest way to sell one. On these three counts, another seller does better.

  • If you need the FDA-approved pen rather than a compounded vial, consider WellMedRx.
  • If the standing monthly cost is what decides it, consider Collective (from $59/mo + membership).
  • If you want a human checking in, not just a prescription, consider Eden.

If none of these fits, our guide to alternatives to PlexusDx sets more sellers in the same category beside PlexusDx on price, states and what the price includes.

Alternatives to PlexusDx

9.1/ 10
Verified partner

Collective

Best for: flat any-dose pricing, if you can absorb a $199 annual membership on top

★★★★★9.1/10

Editorial score · methodology

$59/mo+ membership
CompoundedSemaglutideTirzepatide
Get StartedRead full Collective review →
9.3/ 10
Verified partner

Embody

Best for: a flat compounded tirzepatide or semaglutide price at every dose, from a seller that names its pharmacies

★★★★★9.3/10

Editorial score · methodology

$79/mo
CompoundedSemaglutideTirzepatideGlutathioneNAD+
Get StartedRead full Embody review →
7.9/ 10
Verified partner

Luvo Health

Best for: moving between compounded and brand without changing seller

★★★★☆7.9/10

Editorial score · methodology

$179/mo
CompoundedSemaglutideTirzepatideGonadorelinNAD+LegitScript Verified
Get StartedRead full Luvo Health review →

Compare PlexusDx head to head

Our head-to-head pages for PlexusDx are PlexusDx vs Embody, PlexusDx vs CoreAge Rx, PlexusDx vs Gala, PlexusDx vs Direct Meds, and PlexusDx vs SkinnyRx.

Frequently Asked Questions

PlexusDx sells compounded semaglutide at $149 a month and compounded tirzepatide at $189, as weekly injections or daily tablets, plus a microdose GLP-1 plan at $99. One price covers the visit, drug and shipping, and it does not rise with the dose; prepaying a year cuts the rate to $99 and $129. Lone Star Virtual Health prescribes and Vials RX in Texas fills. An optional genetic test is $99 after the first month. We rate it 8.0/10 overall.
PlexusDx starts at $99 a month, but that is for its microdose tier; its standard injectable starts at $149. The pricing table above lists every tier.
Ask PlexusDx whether it serves your state before you start the intake, and get the answer in writing.
PlexusDx lists compounded semaglutide and compounded tirzepatide. A needle-free oral form is listed as well.
PlexusDx lists compounded GLP-1s only. A licensed compounding pharmacy prepares them: same active ingredient as the brand drug, lower cash price, and no FDA approval of the finished product. That last part is the one readers underestimate, and the review above says why.
Check whether PlexusDx bills your insurance before you sign up. Compounded GLP-1s are rarely covered by insurance, so plan on paying the listed cash price.
PlexusDx says the price covers medication, the clinician visit and shipping. The strip near the top of this review shows what is included and what is not.
You fill in an online intake, a licensed clinician decides whether a GLP-1 is appropriate, and if the answer is yes the medication ships to you. PlexusDx runs that whole sequence on its own site.
We found no FDA warning letters issued to PlexusDx. Before you buy, weigh these: Confirm it serves your state before you start the intake. Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality. None of them rules PlexusDx out, but each is worth settling before you pay.
Other sellers we cover include SnagRx, Lttl, and YourEra. Which one fits depends on the medication, the monthly price you can sustain and whether it ships to your state, so compare those three facts before you switch.

How to check PlexusDx yourself

Glossary

The words sellers use, defined. Tap any term.

Sources

Cited across this PlexusDx review: primary regulatory filings, and peer-reviewed studies.

Sources & methodology — as of October 2026
  1. 1.GLP Watchdog — GLP-1 Pricing Index 2026 (our independent dataset)— GLP Watchdog.
  2. 2.FDA — Compounding and the 503A Pharmacy Framework— U.S. Food & Drug Administration.
  3. 3.FDA — Drug Shortages Database (current shortage listings)— U.S. Food & Drug Administration.
  4. 4.PCAB — Pharmacy Compounding Accreditation Board Standards— Accreditation Commission for Health Care (ACHC) / PCAB.
  5. 5.KFF — Medicaid coverage research (anti-obesity & GLP-1 drug policy)— Kaiser Family Foundation.
  6. 6.STEP 1 Trial — Once-Weekly Semaglutide in Adults with Overweight or Obesity (Wilding JPH et al.)— New England Journal of Medicine.PMID: 33567185.
  7. 7.FDA — Wegovy (semaglutide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
  8. 8.FDA — Ozempic (semaglutide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
  9. 9.SURMOUNT-1 Trial — Tirzepatide Once Weekly for the Treatment of Obesity (Jastreboff AM et al.)— New England Journal of Medicine.PMID: 35658024.
  10. 10.FDA — Zepbound (tirzepatide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
  11. 11.FDA — Mounjaro (tirzepatide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
  12. 12.SURMOUNT-5 Trial — Tirzepatide vs. Semaglutide Head-to-Head in Obesity (Aronne LJ et al.)— New England Journal of Medicine.PMID: 40353578.

See PlexusDx's current pricing

Plans start at $99 a month. Whether you qualify is a clinician's decision, made after your intake.