Semaglutide
Every GLP-1 the FDA has approved, and the active ingredient inside each one.
Definition
The active ingredient in Wegovy, Ozempic and Rybelsus. Its roughly seven-day half-life is what allows weekly injection. When a seller lists “semaglutide” at a fraction of brand pricing, they mean a compounded preparation of this molecule, not the approved product — a distinction their pricing page often blurs.
GLP Watchdog writes these definitions from FDA labels and peer-reviewed PubMed literature. Not one of them is an AI-generated summary.
Other terms under Drugs and brands
Where the evidence lives
- Semaglutide drug page
- The full GLP-1 glossary (149 terms, 8 categories)
- Research articles — written from primary sources
- Tools and calculators
- Compare GLP-1 telehealth providers