Half-life
The practical ones: titration, half-life, washout, and what a missed dose does.
What is Half-life?
How long it takes plasma concentration to halve.
Semaglutide about 7 days, tirzepatide about 5, liraglutide about 13 hours, orforglipron about 36. It decides weekly against daily dosing, and it decides how long a drug lingers after you stop — which is the number that matters for washout and pregnancy planning.
GLP Watchdog writes these definitions from FDA labels and peer-reviewed PubMed literature.
Where Half-life comes up on this site
On GLP Watchdog, Half-life comes up in 4 research articles and 1 tool.
Research that discusses it
Tools that use it
Other terms under Dosing
Where the evidence lives
- The full GLP-1 glossary (149 terms, 8 categories)
- Research articles — written from primary sources
- Tools and calculators
- Compare GLP-1 telehealth providers