Half-life
The practical ones: titration, half-life, washout, and what a missed dose does.
Definition
How long it takes plasma concentration to halve. Semaglutide about 7 days, tirzepatide about 5, liraglutide about 13 hours, orforglipron about 36. It decides weekly against daily dosing, and it decides how long a drug lingers after you stop — which is the number that matters for washout and pregnancy planning.
How long does a GLP-1 stay in your system →
GLP Watchdog writes these definitions from FDA labels and peer-reviewed PubMed literature. Not one of them is an AI-generated summary.
Other terms under Dosing
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