Tirzepatide
Every GLP-1 the FDA has approved, and the active ingredient inside each one.
What is Tirzepatide?
The active ingredient in Mounjaro and Zepbound, a dual GLP-1 and GIP agonist with a roughly five-day half-life.
It is the only injectable in the class carrying an FDA-mandated oral contraceptive interaction warning, which is a real thing to raise with a prescriber rather than a footnote.
GLP Watchdog writes these definitions from FDA labels and peer-reviewed PubMed literature.
Where Tirzepatide comes up on this site
On GLP Watchdog, Tirzepatide comes up in 90 research articles, 493 seller reviews, 113 FDA warning letters and 4 tools. Browse the FDA warning letters.
Research that discusses it
- Is There a Tirzepatide Pill? What Sellers Ship
- Tirzepatide With Glycine, B6 or Niacinamide
- How Long Do Semaglutide and Tirzepatide Side Effects Last?
- A Biologic Plus Tirzepatide for Psoriasis
- Tirzepatide in Ten- to Seventeen-Year-Olds
- Injection Site Reactions: Where Semaglutide and Tirzepatide Really Differ
- All 90 articles are on the research page
Drug pages
Tools that use it
Seller reviews that mention it
Other terms under Drugs and brands
Where the evidence lives
- Tirzepatide drug page
- The full GLP-1 glossary (149 terms, 8 categories)
- Research articles — written from primary sources
- Tools and calculators
- Compare GLP-1 telehealth providers