Tryozi Review
Semaglutide & tirzepatide GLP-1 weight-loss telehealth · Independently scored 7/10
Best for: coverage in all 50 states, which most sellers will not confirm
Tryozi's strongest column is the clinical side: which molecules it will prescribe, and how it handles dosing.
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then $279/mo ongoing
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
Prices checked August 2026
Compounded GLP-1 injections at a flat price that holds as the dose rises. This Florida seller names all four of the 503A compounding pharmacies behind it.
Is Tryozi legit?
Yes. Tryozi is a real, operating US company, and we found no FDA warning letters issued to it. Its site shows LegitScript certification. We rate it 7.0/10 overall, across six areas from price to trust and safety. Legitimate is not the same as right for you, though: that part is a decision for you and a licensed clinician.
Is there a Tryozi promo or coupon code?
Tryozi has no coupon code to enter. New patients are currently quoted $139 for the first month, then $279 a month, and the discount applies on its own. Coupon sites advertising a "Tryozi promo code" are not a source we can vouch for.
See how Tryozi compares on our rankings of the best semaglutide providers and the best tirzepatide providers.
Vetted alternatives to Tryozi
Editorial score · methodology
Editorial score · methodology
Embody
Best for: knowing which pharmacy fills the vial: it names RedRock Pharmacy
Editorial score · methodology
Tryozi at a glance
- Type
- GLP-1 telehealth provider
- Medications
- Semaglutide, Tirzepatide
- Starting price
- $279/mo
- Pricing model
- Flat: the price stays the same as the dose goes up
- What's included
- Medication · Consult · Shipping
- Availability
- All 50 states
- FDA status
- No FDA warning letters found
How Tryozi scores
Six columns, each one computed from something Tryozi has published rather than from an opinion we formed: what it charges, which molecules it will dispense, what its record shows, and what the monthly figure actually buys. Where a seller keeps something back, such as its price or its pharmacy, the score reflects it. Every seller we review goes through the same six columns.
Value25%
2.0/10$279/month is 51% above the $185 median for compounded semaglutide across the sellers we compare.
Effectiveness25%
10.0/10Dispenses semaglutide and tirzepatide, compounded only. Anchored to SURMOUNT-1 (tirzepatide, -20.9%) and STEP 1 (semaglutide, -14.9%).
User Experience15%
8.0/10A price is shown before the questionnaire starts.
Trust & Safety15%
7.5/10No pharmacy is named for its prescriptions. It shows a price before asking for health information. It lists the states it serves.
Accessibility10%
10.0/10Serves 50 of 50 states.
Support10%
7.0/10The price covers the medication, clinician visits and shipping.
A seller that shows no price until after the medical intake loses points on User Experience and Trust & Safety, and its review says so. How we score →
What we checked on Tryozi
Last checked August 2026- Checked the listed price across 2 dose or plan tiers
- Checked state coverage: all 50
- Checked what the monthly price covers, and what it leaves out
- Checked FDA warning letters for Tryozi
Price, availability, and compliance here are read off the seller's own pages and off primary regulatory records, named in the sources below.
What signing up with Tryozi involves
What to expect on the way to a prescription: where the price appears, who fills the medication, and what the monthly price covers. It is not medical advice, and a clinician makes the prescribing decision.
- 1Tryozi shows a price on its own site before asking anything about you, so you can compare it with other sellers before you start a questionnaire.
- 2Ask Tryozi which pharmacy fills the prescription before you pay. The pharmacy's name is what lets you check its license.
- 3The monthly price includes the medication, clinician visits and shipping.
- Lowest ongoing monthly price: semaglutide $279, tirzepatide $379. That leaves out membership fees, first-month rates and insurance copays.
- Tryozi serves all 50 states.
- The medication is compounded, so it is not an FDA-approved product and has not been reviewed by the agency for safety, effectiveness or manufacturing quality.
Contacting Tryozi
- Phone
- (336) 365-0623
- Tryozi offers email support
Cancelling Tryozi
Taken from the terms Tryozi publishes. Terms change, so check the current policy before you subscribe.
- Cancel any time
- Yes
- Minimum commitment
- Month-to-month available; 12, 24 and 52-week plans are billed once upfront
- Refund policy
- See Cancellation & Refund policy
GLP-1 medications Tryozi offers
Each one has its own guide: how the molecule works, the dosing schedule, the side effects that show up in practice, and what the trials actually measured.
Pricing
Prices re-verified
First 4 weeks $139 (50% off), then $279/mo. Multi-week plans are billed once and ship every 4 weeks: 12-week -22%, 24-week -29%, 52-week -47%.
First 4 weeks $189, then $379/mo, per the same first-month 50% structure.
Check the price yourself before you pay
Every figure here was read off Tryozi's own checkout on the date shown. Sellers move prices without announcing it, and promotional rates lapse, so confirm the standing cost on their site before committing.
In its favor
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- The monthly price stays the same as your dose goes up
- The monthly price includes the medication, clinician visits and shipping
- Serves all 50 states
- We found no FDA warning letters issued to Tryozi
Against it
- Semaglutide costs $279 a month, 51% above the $185 median for compounded semaglutide across the sellers we compare
- Tirzepatide costs $379 a month, 52% above the $250 median for compounded tirzepatide across the sellers we compare
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
What Tryozi charges
The figure Tryozi leads with is $139, and it is a first-month rate. From month two the price is $279/month, which is the number to plan around. There is nothing wrong with an introductory offer; it just is not the price of staying on the medication.
- Compounded semaglutide: $139 first month, then $279/month
- Compounded tirzepatide: $189 first month, then $379/month
For compounded semaglutide, the median across the sellers we compare is $185/month, so Tryozi's $279 is a premium, and a premium has to buy something. Discounting the first month does not change the twelve-month total by much.
Direct Meds dispenses semaglutide and tirzepatide from $249/month, which makes it the fair comparison to run before you commit here.
What Tryozi dispenses
Tryozi prescribes semaglutide (approved as Wegovy and Ozempic) and tirzepatide (approved as Zepbound and Mounjaro). Between them these are the two molecules with the largest published weight-loss trial programs behind them. The medication is compounded rather than dispensed as an approved pen. Compounding serves real clinical needs and is entirely lawful; what it is not is reviewed, and the cost difference reflects that.
Safety and disclosure
Tryozi tells you its price before you start the medical questionnaire and that it treats patients in all 50 states. We found no FDA warning letters issued to Tryozi. Because the medication is compounded, the most useful question to ask at intake is which licensed pharmacy fills the prescription. If Tryozi will not tell you, treat that as a warning sign. How we weigh oversight, disclosure and price is set out in our scoring methodology.
Who should look elsewhere
- You care most about the twelve-month total, not the first bill. A flat-rate seller such as Collective will usually win that math.
- You would be choosing on the advertised figure. The introductory month is real, but it is not what you will pay in month three.
- You want the FDA-approved pen specifically. Everything listed here is compounded.
- You need insurance to cover the cost. Check whether Tryozi bills your plan before you start.
It fits if
- you want the price to stop moving as your dose climbs
- you want a cheap way to find out whether the medication suits you before committing
- you need access wherever you live
Our read
Tryozi is a cheap way to start and an ordinary way to continue. Use the $139 month for what it is good for, finding out whether the medication works for you, and re-run the numbers against $279/month before you let it renew twice. MangoRx is the nearest comparison we review, and worth reading alongside this.
The Bottom Line
Tryozi's strongest column is the clinical side: which molecules it will prescribe, and how it handles dosing.
Before you pay Tryozi
Starting at $139 a month. Check today's price, then start the intake.
Where Tryozi is the wrong choice
No seller suits every reader, and pretending otherwise is the easiest way to sell one. On these three counts, another seller does better.
- If you need the FDA-approved pen rather than a compounded vial, consider Sesame Care.
- If the standing monthly cost is what decides it, consider Collective (from $59/mo).
- If you want a human checking in, not just a prescription, consider ShedRx.
Compare Tryozi head to head
The sellers closest to Tryozi on medication and price.
Frequently Asked Questions
Glossary
The words sellers use, defined. Tap any term.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Sources
Cited across this Tryozi review: primary regulatory filings, and peer-reviewed studies.
Sources & methodology — as of August 2026
- 1.GLP Watchdog — GLP-1 Pricing Index 2026 (our independent dataset)— GLP Watchdog.
- 2.FDA — Compounding and the 503A Pharmacy Framework— U.S. Food & Drug Administration.
- 3.FDA — Drug Shortages Database (current shortage listings)— U.S. Food & Drug Administration.
- 4.PCAB — Pharmacy Compounding Accreditation Board Standards— Accreditation Commission for Health Care (ACHC) / PCAB.
- 5.KFF — Medicaid coverage research (anti-obesity & GLP-1 drug policy)— Kaiser Family Foundation.
- 6.STEP 1 Trial — Once-Weekly Semaglutide in Adults with Overweight or Obesity (Wilding JPH et al.)— New England Journal of Medicine.PMID: 33567185.
- 7.FDA — Wegovy (semaglutide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
- 8.FDA — Ozempic (semaglutide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
- 9.SURMOUNT-1 Trial — Tirzepatide Once Weekly for the Treatment of Obesity (Jastreboff AM et al.)— New England Journal of Medicine.PMID: 35658024.
- 10.FDA — Zepbound (tirzepatide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
- 11.FDA — Mounjaro (tirzepatide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
- 12.SURMOUNT-5 Trial — Tirzepatide vs. Semaglutide Head-to-Head in Obesity (Garvey WT et al.)— New England Journal of Medicine.PMID: 40334173.
See Tryozi's current pricing
Plans start at $139 a month. Whether you qualify is a clinician's decision, made after your intake.