MariTide (Maridebart Cafraglutide)
Every GLP-1 the FDA has approved, and the active ingredient inside each one.
What is MariTide (Maridebart Cafraglutide)?
Amgen's investigational once-monthly conjugate, maridebart cafraglutide, pairing a GLP-1 agonist with a GIP ANTAGONIST.
Phase 2 (NEJM 2025) reported 16–20% weight loss. The GIP direction is the opposite of tirzepatide's, which is why it is interesting rather than incremental. Not approved.
GLP-1 pipeline: survodutide, MariTide, ecnoglutide →
GLP Watchdog writes these definitions from FDA labels and peer-reviewed PubMed literature.
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