GLP-1 in pregnancy

Definition

Every approved GLP-1 carries a pregnancy precaution, with discontinuation recommended at least two months ahead of a planned conception for semaglutide given its half-life. Animal studies show developmental toxicity at human-equivalent doses; there are no randomized human data and observational registries are still accumulating. Reliable contraception matters for anyone of reproductive age. ⚠ Accidental early exposure is not in itself an indication for termination — that is a conversation for a maternal-fetal medicine specialist.

Wegovy cheat sheet (red flags) →

GLP Watchdog writes these definitions from FDA labels and peer-reviewed PubMed literature. Not one of them is an AI-generated summary.

Other terms under Patient experience

• Plateau
• Microdosing
• Switching GLP-1s
• Rebound weight gain
• GLP-1 + anesthesia (preoperative)
• Subcutaneous (subq) injection
• Intensive Behavioral Therapy (IBT)

Where the evidence lives

• Wegovy cheat sheet (red flags)
• The full GLP-1 glossary (149 terms, 8 categories)
• Research articles — written from primary sources
• Tools and calculators
• Compare GLP-1 telehealth providers