MediRX Review
Semaglutide & tirzepatide GLP-1 weight-loss telehealth · Independently scored 7.5/10
Best for: compounded semaglutide at $149/month
MediRX's strongest column is the clinical side: which molecules it will prescribe, and how it handles dosing.
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Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
Prices checked August 2026
Injections of compounded semaglutide start at $149/month, tirzepatide at $199/month, and NAD+ plus a name-brand GLP-1 option are also on the list. OpenLoop Health supplies the clinical layer: a licensed provider reads your online intake, writes where appropriate, and OpenLoop's partnered US licensed pharmacies fill it. The site holds LegitScript Certified status and discloses its entity, MediRX, Inc. of Wyoming. Exactly which states it serves goes unpublished.
Is MediRX legit?
Yes. MediRX is a real, operating US company, and we found no FDA warning letters issued to it. Its site shows LegitScript certification. We rate it 7.5/10 overall, across six areas from price to trust and safety. Legitimate is not the same as right for you, though: that part is a decision for you and a licensed clinician.
Is there a MediRX promo or coupon code?
MediRX has no code to type in. The current offer: NEW YEAR PROMO: $120 off your first month (automatic. Monthly plan e.g. $129 first month, then standard $239-$249/mo after. GLP-1 semaglutide/tirzepatide. It applies at checkout on its own. Coupon sites advertising a "MediRX promo code" are not a source we can vouch for.
See how MediRX compares on our rankings of the best semaglutide providers and the best tirzepatide providers.
Vetted alternatives to MediRX
Trimi Health
Best for: knowing which pharmacy fills the vial: it names VialsRx
Editorial score · methodology
Editorial score · methodology
Editorial score · methodology
MediRX at a glance
- Type
- GLP-1 telehealth provider
- Medications
- Semaglutide from $149, Tirzepatide from $199
- Starting price
- $149/mo
- What's included
- Consult · Shipping · Medication
- FDA status
- No FDA warning letters found
How MediRX scores
Six columns, each one computed from something MediRX has published rather than from an opinion we formed: what it charges, which molecules it will dispense, what its record shows, and what the monthly figure actually buys. Where a seller keeps something back, such as its price or its pharmacy, the score reflects it. Every seller we review goes through the same six columns.
Value25%
6.6/10$199/month is 20% below the $250 median for compounded tirzepatide across the sellers we compare.
Effectiveness25%
10.0/10Dispenses semaglutide and tirzepatide, compounded only. Anchored to SURMOUNT-1 (tirzepatide, -20.9%) and STEP 1 (semaglutide, -14.9%).
User Experience15%
8.0/10A price is shown before the questionnaire starts.
Trust & Safety15%
6.5/10No pharmacy is named for its prescriptions. It shows a price before asking for health information.
Accessibility10%
5.0/10No state list is available to check, so this is held at the midpoint rather than scored on reach.
Support10%
7.0/10The price covers the medication, clinician visits and shipping.
A seller that shows no price until after the medical intake loses points on User Experience and Trust & Safety, and its review says so. How we score →
What we checked on MediRX
Last checked August 2026- Checked the listed price across 2 dose or plan tiers
- Checked what the monthly price covers, and what it leaves out
- Checked FDA warning letters for MediRX
Price, availability, and compliance here are read off the seller's own pages and off primary regulatory records, named in the sources below.
What signing up with MediRX involves
What to expect on the way to a prescription: where the price appears, who fills the medication, and what the monthly price covers. It is not medical advice, and a clinician makes the prescribing decision.
- 1MediRX shows a price on its own site before asking anything about you, so you can compare it with other sellers before you start a questionnaire.
- 2Ask MediRX which pharmacy fills the prescription before you pay. The pharmacy's name is what lets you check its license.
- 3The monthly price includes the medication, clinician visits and shipping.
- Lowest ongoing monthly price: semaglutide $149, tirzepatide $199. That leaves out membership fees, first-month rates and insurance copays.
- Confirm that MediRX serves your state before you start.
- The medication is compounded, so it is not an FDA-approved product and has not been reviewed by the agency for safety, effectiveness or manufacturing quality.
Contacting MediRX
- Phone
- (307) 323-3550
- MediRX offers email support
Cancelling MediRX
Taken from the terms MediRX publishes. Terms change, so check the current policy before you subscribe.
- Minimum commitment
- None
- Refund policy
- Not published by the seller
GLP-1 medications MediRX offers
Each one has its own guide: how the molecule works, the dosing schedule, the side effects that show up in practice, and what the trials actually measured.
Pricing
Prices re-verified
Starting at; $120 off first month, as low as $70 first month on the 6-month plan
Starting at; $239-$249/mo after on shorter plans, $120 off first month
Check the price yourself before you pay
Every figure here was read off MediRX's own checkout on the date shown. Sellers move prices without announcing it, and promotional rates lapse, so confirm the standing cost on their site before committing.
In its favor
- Semaglutide costs $149 a month, 19% below the $185 median for compounded semaglutide across the sellers we compare
- Tirzepatide costs $199 a month, 20% below the $250 median for compounded tirzepatide across the sellers we compare
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- The monthly price includes the medication, clinician visits and shipping
- We found no FDA warning letters issued to MediRX
Against it
- Confirm it serves your state before you start the intake
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
What MediRX charges
The standing price at MediRX is $149/month.
- Semaglutide: $149/month
- Tirzepatide: $199/month
For compounded tirzepatide, the median across the sellers we compare is $250/month, so MediRX's $199 is genuinely below the middle, not just advertised that way.
Found, at about $149/month, is the closest like-for-like alternative we review.
What MediRX dispenses
MediRX prescribes semaglutide (approved as Wegovy and Ozempic) and tirzepatide (approved as Zepbound and Mounjaro). Between them these are the two best-evidenced weight-loss molecules currently on the market.
Safety and disclosure
MediRX tells you its price before you start the medical questionnaire. We found no FDA warning letters issued to MediRX. How we weigh oversight, disclosure and price is set out in our scoring methodology.
Who should look elsewhere
- You need insurance to cover the cost. Check whether MediRX bills your plan before you start.
It fits if
- the lowest standing monthly cost is what you are solving for
Our read
MediRX competes on price without an obvious sacrifice elsewhere: $199/month for compounded tirzepatide, no FDA warning letters.
The Bottom Line
MediRX's strongest column is the clinical side: which molecules it will prescribe, and how it handles dosing.
Before you pay MediRX
Starting at $149 a month. Check today's price, then start the intake.
Where MediRX is the wrong choice
No seller suits every reader, and pretending otherwise is the easiest way to sell one. On these three counts, another seller does better.
- If you need the FDA-approved pen rather than a compounded vial, consider Sesame Care.
- If the standing monthly cost is what decides it, consider Collective (from $59/mo).
- If you want a human checking in, not just a prescription, consider ShedRx.
Compare MediRX head to head
The sellers closest to MediRX on medication and price.
Frequently Asked Questions
Glossary
The words sellers use, defined. Tap any term.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Sources
Cited across this MediRX review: primary regulatory filings, and peer-reviewed studies.
Sources & methodology — as of August 2026
- 1.GLP Watchdog — GLP-1 Pricing Index 2026 (our independent dataset)— GLP Watchdog.
- 2.FDA — Compounding and the 503A Pharmacy Framework— U.S. Food & Drug Administration.
- 3.FDA — Drug Shortages Database (current shortage listings)— U.S. Food & Drug Administration.
- 4.PCAB — Pharmacy Compounding Accreditation Board Standards— Accreditation Commission for Health Care (ACHC) / PCAB.
- 5.KFF — Medicaid coverage research (anti-obesity & GLP-1 drug policy)— Kaiser Family Foundation.
- 6.STEP 1 Trial — Once-Weekly Semaglutide in Adults with Overweight or Obesity (Wilding JPH et al.)— New England Journal of Medicine.PMID: 33567185.
- 7.FDA — Wegovy (semaglutide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
- 8.FDA — Ozempic (semaglutide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
- 9.SURMOUNT-1 Trial — Tirzepatide Once Weekly for the Treatment of Obesity (Jastreboff AM et al.)— New England Journal of Medicine.PMID: 35658024.
- 10.FDA — Zepbound (tirzepatide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
- 11.FDA — Mounjaro (tirzepatide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
- 12.SURMOUNT-5 Trial — Tirzepatide vs. Semaglutide Head-to-Head in Obesity (Garvey WT et al.)— New England Journal of Medicine.PMID: 40334173.
See MediRX's current pricing
Plans start at $149 a month. Whether you qualify is a clinician's decision, made after your intake.