MediRX Review
Semaglutide & tirzepatide GLP-1 weight-loss telehealth · Independently scored 7.3/10
Best for: compounded GLP-1 injections or tablets through OpenLoop's clinician network
MediRX scores highest on the clinical side (which drugs it prescribes and how it doses) and lowest on price. It charges from $149 a month.
Some of the links on this page earn us money. If you sign up with a provider after following one, that provider may pay GLP Watchdog a commission. Learn more
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
Prices checked October 2026
MediRX lists compounded semaglutide injections from $149 a month and tirzepatide from $199, plus semaglutide and tirzepatide dissolvable tablets from $249 and $279 and brand-name options. The same homepage also prices the two injections from $179 and $399. OpenLoop Health's clinicians prescribe and its partner pharmacies fill. MediRX, Inc. of Wyoming runs the site, which shows a LegitScript badge. It publishes no state list.
Is MediRX legit?
Yes. MediRX is a real, operating US company, and we found no FDA warning letters issued to it. Its site shows LegitScript certification. We rate it 7.3/10 overall, across six areas from price to trust and safety. Legitimate is not the same as right for you, though: that part is a decision for you and a licensed clinician.
Is there a MediRX promo or coupon code?
MediRX has no code to type in. The current offer: NEW YEAR PROMO: $120 off your first month (automatic. Monthly plan e.g. $129 first month, then standard $239-$249/mo after. GLP-1 semaglutide/tirzepatide. It applies at checkout on its own. Coupon sites advertising a "MediRX promo code" are not a source we can vouch for.
See how MediRX compares on our rankings of the best semaglutide providers and the best tirzepatide providers.
Vetted alternatives to MediRX
Collective
Best for: flat any-dose pricing, if you can absorb a $199 annual membership on top
Editorial score · methodology
Embody
Best for: a flat compounded tirzepatide or semaglutide price at every dose, from a seller that names its pharmacies
Editorial score · methodology
Luvo Health
Best for: moving between compounded and brand without changing seller
Editorial score · methodology
MediRX at a glance
- Type
- GLP-1 telehealth provider
- Medications
- Semaglutide from $149, Tirzepatide from $199
- Starting price
- $149/mo
- What's included
- Consult · Shipping · Medication
- Availability
- All 50 states + DC
- FDA status
- No FDA warning letters found
How MediRX scores
Six columns, each one computed from something MediRX has published rather than from an opinion we formed: what it charges, which molecules it will dispense, what its record shows, and what the monthly figure actually buys. Where a seller keeps something back, such as its price or its pharmacy, the score reflects it. Every seller we review goes through the same six columns.
Value25%
3.0/10The listed figure is not a comparable monthly price for a named GLP-1 (it may be a membership fee, an insured copay, a per-vial rate or a starting-dose price), so Value is capped rather than scored against other sellers.
Effectiveness25%
10.0/10Dispenses semaglutide and tirzepatide, compounded only. Anchored to SURMOUNT-1 (tirzepatide, -20.9%) and STEP 1 (semaglutide, -14.9%).
User Experience15%
8.0/10A price is shown before the questionnaire starts.
Trust & Safety15%
7.5/10No pharmacy is named for its prescriptions. It shows a price before asking for health information. It lists the states it serves.
Accessibility10%
10.0/10Serves all 50 states and DC.
Support10%
7.0/10The price covers the medication, clinician visits and shipping.
A seller that shows no price until after the medical intake loses points on User Experience and Trust & Safety, and its review says so. How we score →
What we checked on MediRX
Last checked October 2026- Checked the listed price across 2 dose or plan tiers
- Checked state coverage: all 50
- Checked what the monthly price covers, and what it leaves out
- Checked FDA warning letters for MediRX
Price, availability, and compliance here are read off the seller's own pages and off primary regulatory records, named in the sources below.
What signing up with MediRX involves
What to expect on the way to a prescription: where the price appears, who fills the medication, and what the monthly price covers. It is not medical advice, and a clinician makes the prescribing decision.
- 1MediRX shows a price on its own site before asking anything about you, so you can compare it with other sellers before you start a questionnaire.
- 2Ask MediRX which pharmacy fills the prescription before you pay. The pharmacy's name is what lets you check its license.
- 3The monthly price includes the medication, clinician visits and shipping.
- Before you commit, get the ongoing monthly price of the medication itself, not a first-month rate, a membership fee or a per-vial price.
- MediRX serves all 50 states and DC.
Contacting MediRX
- Phone
- (307) 323-3550
- MediRX offers email support
Cancelling MediRX
Taken from the terms MediRX publishes. Terms change, so check the current policy before you subscribe.
- Cancel any time
- Yes
- Minimum commitment
- None; subscriptions auto-renew until canceled
- Refund policy
- Full refund for the billing cycle if a provider finds you ineligible; otherwise limited and subject to provider policy.
- Early-termination fee
- None
Medications MediRX lists
MediRX lists compounded semaglutide and compounded tirzepatide. Each one has its own guide: how it works, the dosing schedule, the side effects that show up in practice, and what the trials measured.
Pricing
Prices re-verified
Homepage card "Starting at $149"; a second card on the same page says "Starting at $179". Plan length behind the starting price is not shown.
Homepage card "Starting at $199"; a second card on the same page says "Starting at $399". Plan length behind the starting price is not shown.
Check the price yourself before you pay
Every figure here comes from MediRX's own website, as of the date shown. Sellers move prices without announcing it, and promotional rates lapse, so confirm the standing cost on their site before committing.
In its favor
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- The monthly price includes the medication, clinician visits and shipping
- Serves all 50 states and DC
- We found no FDA warning letters issued to MediRX
Against it
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
What MediRX charges
The standing price at MediRX is $149/month. Before you pay, compare MediRX's cancellation terms with other sellers' cancellation and refund policies.
- Compounded semaglutide: $149/month
- Compounded tirzepatide: $199/month
Found, at about $149/month + membership, is the closest like-for-like alternative we review.
What MediRX dispenses
MediRX prescribes semaglutide (approved as Wegovy and Ozempic) and tirzepatide (approved as Zepbound and Mounjaro). Between them these are the two best-evidenced weight-loss molecules currently on the market. The medication is compounded rather than dispensed as an approved pen. Compounding serves real clinical needs and is entirely lawful; what it is not is reviewed, and the cost difference reflects that. The molecule can be the one in Ozempic and Wegovy; what differs is the formulation, the concentration and the dose ladder.
A needle-free oral option is genuinely uncommon and is the reason some readers will look at MediRX at all. Set expectations on the evidence, though: the published weight-loss trials for these molecules used injections. Oral and sublingual delivery of peptides is far less studied, so treat it as a route that solves the needle problem rather than as a proven equal to the shot.
Safety and disclosure
MediRX tells you its price before you start the medical questionnaire and that it treats patients in all 50 states. We found no FDA warning letters issued to MediRX. Because the medication is compounded, the most useful question to ask at intake is which licensed pharmacy fills the prescription. If MediRX will not tell you, treat that as a warning sign. A 503A pharmacy answers to a state board and a 503B facility to the FDA; which one fills it changes what you can check. How we weigh oversight, disclosure and price is set out in our scoring methodology.
Who should look elsewhere
- You want the FDA-approved pen specifically. Everything listed here is compounded.
- You need insurance to cover the cost. Check whether MediRX bills your plan before you start.
It fits if
- injections are the thing keeping you from starting
- you need access wherever you live
Our read
MediRX charges $149/month. Too few sellers offer the same drug and form to say whether that is cheap or expensive, so judge it on what the package includes.
The Bottom Line
MediRX scores highest on the clinical side (which drugs it prescribes and how it doses) and lowest on price. It charges from $149 a month.
Before you pay MediRX
Starting at $149 a month. Check today's price, then start the intake.
Where MediRX is the wrong choice
No seller suits every reader, and pretending otherwise is the easiest way to sell one. On these three counts, another seller does better.
- If you need the FDA-approved pen rather than a compounded vial, consider WellMedRx.
- If the standing monthly cost is what decides it, consider Collective (from $59/mo + membership).
- If you want a human checking in, not just a prescription, consider Eden.
If none of these fits, our guide to alternatives to MediRX sets more sellers in the same category beside MediRX on price, states and what the price includes.
Frequently Asked Questions
How to check MediRX yourself
- Buying Tirzepatide as a Research Chemical: What "Research Use Only" Really Means
- How to Get a GLP-1 Prescription
- Is Ozempic Available Over the Counter? No GLP-1 Is, and What Is Sold Instead
Every seller that ships to your state, side by side: Alaska, Florida, Kentucky, Massachusetts, Nevada, New Hampshire, Oregon, Rhode Island and every other state.
Glossary
The words sellers use, defined. Tap any term.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Sources
Cited across this MediRX review: primary regulatory filings, and peer-reviewed studies.
Sources & methodology — as of October 2026
- 1.GLP Watchdog — GLP-1 Pricing Index 2026 (our independent dataset)— GLP Watchdog.
- 2.FDA — Compounding and the 503A Pharmacy Framework— U.S. Food & Drug Administration.
- 3.FDA — Drug Shortages Database (current shortage listings)— U.S. Food & Drug Administration.
- 4.PCAB — Pharmacy Compounding Accreditation Board Standards— Accreditation Commission for Health Care (ACHC) / PCAB.
- 5.KFF — Medicaid coverage research (anti-obesity & GLP-1 drug policy)— Kaiser Family Foundation.
- 6.STEP 1 Trial — Once-Weekly Semaglutide in Adults with Overweight or Obesity (Wilding JPH et al.)— New England Journal of Medicine.PMID: 33567185.
- 7.FDA — Wegovy (semaglutide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
- 8.FDA — Ozempic (semaglutide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
- 9.SURMOUNT-1 Trial — Tirzepatide Once Weekly for the Treatment of Obesity (Jastreboff AM et al.)— New England Journal of Medicine.PMID: 35658024.
- 10.FDA — Zepbound (tirzepatide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
- 11.FDA — Mounjaro (tirzepatide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
- 12.SURMOUNT-5 Trial — Tirzepatide vs. Semaglutide Head-to-Head in Obesity (Aronne LJ et al.)— New England Journal of Medicine.PMID: 40353578.
See MediRX's current pricing
Plans start at $149 a month. Whether you qualify is a clinician's decision, made after your intake.