Trillium Meds logo

Trillium Meds Review

Semaglutide & tirzepatide GLP-1 weight-loss telehealth · Independently scored 8.3/10

Best for: choosing your compounding pharmacy, with every plan priced before intake

8.3
★★★★☆8.3/10

Trillium Meds scores highest on the clinical side (which drugs it prescribes and how it doses) and lowest on follow-up care. It charges from $159 a month; its compounded tirzepatide, at $199, is 26% below the $269 median among the sellers we compare.

Some of the links on this page earn us money. If you sign up with a provider after following one, that provider may pay GLP Watchdog a commission. Learn more

$159/mo

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Charged on top

Coaching

Charged on top

Compare top-rated alternatives ↓

Trillium Meds is a small, owner-run telehealth platform in Portland, Oregon, that connects patients with independent providers and lets them pick the compounding pharmacy. Prices are listed per pharmacy before intake, with no membership fee. One month of compounded semaglutide is $159 and tirzepatide $199; 3-month plans cost less per month but are paid up front.

By Ruth Calder · Enforcement Editor
Editorially reviewed. Not medical advice · How we verify contentLast reviewed
GLP-1 from $159/moPrice shown up frontIncludes medication + consultAll 50 states and DCNo FDA warning letters found

Is Trillium Meds legit?

Yes. Trillium Meds is a real, operating US company, and we found no FDA warning letters issued to it. Its site shows LegitScript certification. We rate it 8.3/10 overall, across six areas from price to trust and safety. Legitimate is not the same as right for you, though: that part is a decision for you and a licensed clinician.

Is there a Trillium Meds promo or coupon code?

We know of no promo or coupon code for Trillium Meds. Its listed price is $159 a month. Coupon sites advertising "Trillium Meds discount codes" are not a source we can vouch for, and any genuine offer shows at checkout without a code.

See how Trillium Meds compares on our rankings of the best semaglutide providers and the best tirzepatide providers.

Vetted alternatives to Trillium Meds

9.1/ 10
Verified partner

Collective

Best for: flat any-dose pricing, if you can absorb a $199 annual membership on top

★★★★★9.1/10

Editorial score · methodology

$59/mo+ membership
CompoundedSemaglutideTirzepatide
Get StartedRead full Collective review →
9.3/ 10
Verified partner

Embody

Best for: a flat compounded tirzepatide or semaglutide price at every dose, from a seller that names its pharmacies

★★★★★9.3/10

Editorial score · methodology

$79/mo
CompoundedSemaglutideTirzepatideGlutathioneNAD+
Get StartedRead full Embody review →
7.9/ 10
Verified partner

Luvo Health

Best for: moving between compounded and brand without changing seller

★★★★☆7.9/10

Editorial score · methodology

$179/mo
CompoundedSemaglutideTirzepatideGonadorelinNAD+LegitScript Verified
Get StartedRead full Luvo Health review →
Trillium Meds logo
8.3 / 10
Our editorial rating
Visit Trillium Meds →

from $159/mo · no insurance needed

Trillium Meds at a glance

Type
GLP-1 telehealth provider
Medications
Compounded Semaglutide, Compounded Tirzepatide
Starting price
$159/mo
What's included
Medication · Consult · Shipping
Availability
All 50 states + DC
FDA status
No FDA warning letters found

How Trillium Meds scores

Six columns, each one computed from something Trillium Meds has published rather than from an opinion we formed: what it charges, which molecules it will dispense, what its record shows, and what the monthly figure actually buys. Where a seller keeps something back, such as its price or its pharmacy, the score reflects it. Every seller we review goes through the same six columns.

Value25%

7.2/10

$199/month is 26% below the $269 median for compounded tirzepatide across the sellers we compare.

Effectiveness25%

10.0/10

Dispenses semaglutide and tirzepatide, compounded only. Anchored to SURMOUNT-1 (tirzepatide, -20.9%) and STEP 1 (semaglutide, -14.9%).

User Experience15%

8.0/10

A price is shown before the questionnaire starts.

Trust & Safety15%

7.5/10

No pharmacy is named for its prescriptions. It shows a price before asking for health information. It lists the states it serves.

Accessibility10%

10.0/10

Serves all 50 states and DC.

Support10%

7.0/10

The price covers the medication, clinician visits and shipping.

6weighted dimensions
734sellers compared
Everychecked against the seller's own site
Value 25%Effectiveness 25%User Experience 15%Trust & Safety 15%Accessibility 10%Support 10%

A seller that shows no price until after the medical intake loses points on User Experience and Trust & Safety, and its review says so. How we score →

What we checked on Trillium Meds

Last checked October 2026
  • Checked the listed price across 2 dose or plan tiers
  • Checked state coverage: all 50
  • Checked what the monthly price covers, and what it leaves out
  • Checked FDA warning letters for Trillium Meds

Price, availability, and compliance here are read off the seller's own pages and off primary regulatory records, named in the sources below.

What signing up with Trillium Meds involves

What to expect on the way to a prescription: where the price appears, who fills the medication, and what the monthly price covers. It is not medical advice, and a clinician makes the prescribing decision.

  1. 1Trillium Meds shows a price on its own site before asking anything about you, so you can compare it with other sellers before you start a questionnaire.
  2. 2Trillium Meds does not require a live video visit or baseline bloodwork before a first prescription.
  3. 3Ask Trillium Meds which pharmacy fills the prescription before you pay. The pharmacy's name is what lets you check its license.
  4. 4The monthly price includes the medication, clinician visits and shipping.
Price shown before you start
  • Lowest ongoing monthly price: semaglutide $159, tirzepatide $199. That leaves out membership fees, first-month rates and insurance copays.
  • Trillium Meds serves all 50 states and DC.
  • The medication is compounded, so it is not an FDA-approved product and has not been reviewed by the agency for safety, effectiveness or manufacturing quality.

Contacting Trillium Meds

Email
Trillium Meds offers email support

Cancelling Trillium Meds

Taken from the terms Trillium Meds publishes. Terms change, so check the current policy before you subscribe.

Minimum commitment
None (2- and 3-month plans optional, paid up front)
Refund policy
Full refund if not eligible; none once sent to the pharmacy

Medications Trillium Meds lists

Trillium Meds lists compounded semaglutide and compounded tirzepatide. Each one has its own guide: how it works, the dosing schedule, the side effects that show up in practice, and what the trials measured.

Pricing

Prices re-verified

1-month plan, any doseCompounded
$159/mo
semaglutide

Same at Hallandale, Southend and OptioRx. 3-month plan $357 paid up front ($119/mo); 3-month starter plan for new patients $257; OptioRx 2-month $279.

1-month plan, any doseCompounded
$199/mo
tirzepatide

Same at Nova, Hallandale, Southend and OptioRx. 3-month plans paid up front: $349 (Drug Crafters) to $499; starter plans for new patients $299 to $399; OptioRx 2-month $349.

Check the price yourself before you pay

Every figure here comes from Trillium Meds's own website, as of the date shown. Sellers move prices without announcing it, and promotional rates lapse, so confirm the standing cost on their site before committing.

See Trillium Meds pricing →

In its favor

  • Semaglutide costs $159 a month, 20% below the $199 median for compounded semaglutide across the sellers we compare
  • Tirzepatide costs $199 a month, 26% below the $269 median for compounded tirzepatide across the sellers we compare
  • Shows its price before the medical questionnaire, so you can compare it without handing over health information
  • The monthly price includes the medication, clinician visits and shipping
  • Serves all 50 states and DC
  • We found no FDA warning letters issued to Trillium Meds

Against it

  • Not included in the monthly price: lab work, coaching
  • Ask which pharmacy fills the prescription before you pay, so you can check its license
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

What Trillium Meds charges

Trillium Meds lists $159/month.

  • Compounded semaglutide: $159/month
  • Compounded tirzepatide: $199/month

For compounded tirzepatide, the median across the sellers we compare is $269/month, so Trillium Meds' $199 is genuinely below the middle, not just advertised that way. Before you pay, compare Trillium Meds' cancellation terms with other sellers' cancellation and refund policies. For scale, the dearest tenth of compounded sellers charges about three times the cheapest tenth.

HealthRX, at about $165/month, is the closest like-for-like alternative we review.

What Trillium Meds dispenses

Trillium Meds prescribes semaglutide (approved as Wegovy and Ozempic) and tirzepatide (approved as Zepbound and Mounjaro). Between them these are the pair carrying the strongest published outcome data. These are compounded preparations from a licensed pharmacy rather than approved pens, which is where the lower price comes from. A compounded drug is not FDA-approved as a finished product: the specific preparation has not been reviewed for safety, efficacy or manufacturing quality. For what differs besides the price, see compounded semaglutide vs Ozempic and Wegovy.

Safety and disclosure

Trillium Meds tells you its price before you start the medical questionnaire and that it treats patients in all 50 states. We found no FDA warning letters issued to Trillium Meds. Because the medication is compounded, the most useful question to ask at intake is which licensed pharmacy fills the prescription. If Trillium Meds will not tell you, treat that as a warning sign. Once you have the pharmacy's name, 503A vs 503B explains which regulator oversees it and how to check. How we weigh oversight, disclosure and price is set out in our scoring methodology.

Who should look elsewhere

  • You want the FDA-approved pen specifically. Everything listed here is compounded.
  • You need insurance to cover the cost. Check whether Trillium Meds bills your plan before you start.

It fits if

  • the lowest standing monthly cost is what you are solving for
  • you need access wherever you live

Our read

Trillium Meds competes on price without an obvious sacrifice elsewhere: $199/month for compounded tirzepatide, no FDA warning letters, and wide state coverage.

The Bottom Line

Trillium Meds scores highest on the clinical side (which drugs it prescribes and how it doses) and lowest on follow-up care. It charges from $159 a month; its compounded tirzepatide, at $199, is 26% below the $269 median among the sellers we compare.

Score: 8.3/10Best for: choosing your compounding pharmacy, with every plan priced before intakeFrom: $159/mo

Before you pay Trillium Meds

Starting at $159 a month. Check today's price, then start the intake.

Where Trillium Meds is the wrong choice

No seller suits every reader, and pretending otherwise is the easiest way to sell one. On these three counts, another seller does better.

  • If you need the FDA-approved pen rather than a compounded vial, consider WellMedRx.
  • If the standing monthly cost is what decides it, consider Collective (from $59/mo + membership).
  • If you want a human checking in, not just a prescription, consider Eden.

If none of these fits, our guide to alternatives to Trillium Meds sets more sellers in the same category beside Trillium Meds on price, states and what the price includes.

Frequently Asked Questions

Trillium Meds is a small, owner-run telehealth platform in Portland, Oregon, that connects patients with independent providers and lets them pick the compounding pharmacy. Prices are listed per pharmacy before intake, with no membership fee. One month of compounded semaglutide is $159 and tirzepatide $199; 3-month plans cost less per month but are paid up front. We rate it 8.3/10 overall.
Trillium Meds starts at $159 a month. The pricing table above lists every tier.
Trillium Meds says it treats patients in all 50 states.
Trillium Meds lists compounded semaglutide and compounded tirzepatide.
Trillium Meds lists compounded GLP-1s only. A licensed compounding pharmacy prepares them: same active ingredient as the brand drug, lower cash price, and no FDA approval of the finished product. That last part is the one readers underestimate, and the review above says why.
Check whether Trillium Meds bills your insurance before you sign up. Compounded GLP-1s are rarely covered by insurance, so plan on paying the listed cash price.
Trillium Meds says the price covers medication, the clinician visit and shipping. Lab work is billed on top. The strip near the top of this review shows what is included and what is not.
You fill in an online intake, a licensed clinician decides whether a GLP-1 is appropriate, and if the answer is yes the medication ships to you. Trillium Meds runs that whole sequence on its own site.
We found no FDA warning letters issued to Trillium Meds. Before you buy, weigh these: Not included in the monthly price: lab work, coaching. Ask which pharmacy fills the prescription before you pay, so you can check its license. Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality. None of them rules Trillium Meds out, but each is worth settling before you pay.
Other sellers we cover include HealthRX, Sesame Care, and ShedRx. Which one fits depends on the medication, the monthly price you can sustain and whether it ships to your state, so compare those three facts before you switch.

How to check Trillium Meds yourself

Every seller that ships to your state, side by side: California, Connecticut, Louisiana, Massachusetts, Montana, North Dakota, South Dakota, Wisconsin and every other state.

Glossary

The words sellers use, defined. Tap any term.

Sources

Cited across this Trillium Meds review: primary regulatory filings, and peer-reviewed studies.

Sources & methodology — as of October 2026
  1. 1.GLP Watchdog — GLP-1 Pricing Index 2026 (our independent dataset)— GLP Watchdog.
  2. 2.FDA — Compounding and the 503A Pharmacy Framework— U.S. Food & Drug Administration.
  3. 3.FDA — Drug Shortages Database (current shortage listings)— U.S. Food & Drug Administration.
  4. 4.PCAB — Pharmacy Compounding Accreditation Board Standards— Accreditation Commission for Health Care (ACHC) / PCAB.
  5. 5.KFF — Medicaid coverage research (anti-obesity & GLP-1 drug policy)— Kaiser Family Foundation.
  6. 6.STEP 1 Trial — Once-Weekly Semaglutide in Adults with Overweight or Obesity (Wilding JPH et al.)— New England Journal of Medicine.PMID: 33567185.
  7. 7.FDA — Wegovy (semaglutide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
  8. 8.FDA — Ozempic (semaglutide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
  9. 9.SURMOUNT-1 Trial — Tirzepatide Once Weekly for the Treatment of Obesity (Jastreboff AM et al.)— New England Journal of Medicine.PMID: 35658024.
  10. 10.FDA — Zepbound (tirzepatide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
  11. 11.FDA — Mounjaro (tirzepatide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
  12. 12.SURMOUNT-5 Trial — Tirzepatide vs. Semaglutide Head-to-Head in Obesity (Aronne LJ et al.)— New England Journal of Medicine.PMID: 40353578.

See Trillium Meds's current pricing

Plans start at $159 a month. Whether you qualify is a clinician's decision, made after your intake.