GLP-1 Providers in South Dakota (2026)

174 sellers list South Dakota as a shipping state. The lowest regular price among them is $79/mo, and South Dakota Medicaid does not cover weight loss.

174 sellersfrom $79/moMedicaid does not cover weight loss

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174 of the 238 sellers that publish a state list include South Dakota, the 38th-most of the 50 states and DC. 128 of them ship to all 50 states, and 1 serves 15 states or fewer. Across the 145 with a regular monthly price, the middle figure is $175/mo.

South Dakota Medicaid does not pay for GLP-1 drugs prescribed only for weight loss. GLP-1s prescribed for type 2 diabetes are covered, with prior authorization.

Featured Partners · South Dakota

Featured GLP-1 providers serving South Dakota

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  1. Top pick
    8.7

    Compounded from

    $129/mo

    Save $1,220/mo vs Wegovy
    Get started →
  2. Compounded from

    $99/mo

    Save $1,250/mo vs Wegovy
    Get started →
  3. Compounded from

    $99/mo

    Save $1,250/mo vs Wegovy
    Get started →
  4. Compounded from

    $99/mo

    Save $1,250/mo vs Wegovy
    Get started →
  5. Compounded from

    $179/mo

    Save $1,170/mo vs Wegovy
    Get started →
  6. Compounded from

    $99/mo

    Save $1,250/mo vs Wegovy
    Get started →

Who Ships GLP-1s to South Dakota

  1. Embody $79/mo
  2. Lean Meds $79/mo
  3. NextMeds $79/mo

Lowest regular prices for South Dakota: Embody at $79/mo, Lean Meds at $79/mo and NextMeds at $79/mo.

Smaller-footprint sellers that include South Dakota: ZYP Medical (6 states).

8 sellers that list 30 or more states leave South Dakota off, among them Superpower, Harmony Wellness Clinic, Mint Med, PreventiveMD and Willow.

Seller counts next door: Iowa 185, Minnesota 180, Montana 179, North Dakota 173, Nebraska 179 and Wyoming 177.

Browse by medication

South Dakota Medicaid and GLP-1 Coverage

South Dakota Medicaid does not pay for GLP-1 drugs prescribed only for weight loss. GLP-1s prescribed for type 2 diabetes are covered, with prior authorization.

Prior authorization
Prior authorization formSD-specific GLP-1 Agonists Prior Authorization Request Form (footer GLP1Agonists_SouthDakotaMedicaid_2026May)
Prior authorization phone1-855-401-4262
Prior authorization fax1-844-403-1029
Urgent decisionwithin 72 hours
Pharmacy benefit managerOptumRx
Enrollmentabout 136,919 people (October 2025)
If the request is denied
Time to file an appeal30 days
Appeals officeSD DSS Office of Administrative Hearings
Appeals phone605.773.6851
Rule that governs itSD Medicaid Reconsideration Reviews Manual (Feb 2025)
Fast-track appealavailable when waiting would put your health at risk
“Most PA requests are adjudicated within 72 hours. A 'clean' request is often adjudicated in less than 24 hours.”
SD Medicaid Pharmacy Services Billing & Policy Manual (December 2025) page 5

In 2025, South Dakota Medicaid paid for at least 15,521 GLP-1 prescriptions, including at least 6,787 for Ozempic and at least 7,486 for Mounjaro, about $15.7 million before manufacturer rebates. Drugs labeled for weight loss made up 0% of that spending.

Medicaid rules checked May 2026. Prescription counts: CMS State Drug Utilization Data. Check your eligibility

Specialist Clinics and Obesity in South Dakota

South Dakota has 67 practices in the federal provider registry that list obesity medicine, endocrinology or bariatric care, 7.25 per 100,000 residents (37th of 51). By specialty: 35 bariatric, 31 endocrinology and 1 obesity medicine. About 37% of adults here had obesity in 2024 (CDC), the 11th-highest rate of the 50 states and DC. Measured against the median state, South Dakota has 1.27 times as much adult obesity per specialist practice.

Every GLP-1 Provider Serving South Dakota

9.3/ 10
Verified partner

Embody

Best for: knowing which pharmacy fills the vial: it names RedRock Pharmacy

★★★★★4.7/5

Editorial score · methodology

$79/mo
CompoundedSemaglutideTirzepatideGlutathioneNAD+
Get StartedRead full Embody review →
9.0/ 10
Verified partner

Live Vital

Best for: semaglutide at $99/month, 48% below the typical price

★★★★★4.5/5

Editorial score · methodology

$99/mo
CompoundedSemaglutideTirzepatideRetatrutideBPC-157
Get StartedRead full Live Vital review →
8.6/ 10
Verified partner

Found

Best for: tirzepatide at $169/month, 37% below the typical price

★★★★☆4.3/5

Editorial score · methodology

$99/mo
CompoundedSemaglutideTirzepatideOrforglipron
Get StartedRead full Found review →
8.4/ 10
Verified partner

Enhance MD

Best for: knowing which pharmacy fills the vial: it names Tru Meds Rx

★★★★☆4.2/5

Editorial score · methodology

$112/mo
CompoundedSemaglutideTirzepatideNAD+
Get StartedRead full Enhance MD review →
6.7/ 10
Verified partner

Eden

Best for: coverage in all 50 states, which most sellers will not confirm

★★★☆☆3.4/5

Editorial score · methodology

$189/mo
CompoundedSemaglutideTirzepatideGHK-CuGlutathioneFDA Warning
Get StartedRead full Eden review →
Open the full A–Z list of 174 providers in South Dakota

312 more sellers publish no state list

Their signup form tells you whether they ship to South Dakota.

6.4/ 10
Verified partner

ShedRx

Best for: oral orforglipron alongside the injectables

★★★☆☆3.2/5

Editorial score · methodology

$149/mo
CompoundedSemaglutideTirzepatideOrforglipronGHK-Cu
Get StartedRead full ShedRx review →
6.6/ 10
Verified partner

Luvo Health

Best for: moving between compounded and brand without changing seller

★★★☆☆3.3/5

Editorial score · methodology

$249/mo
CompoundedSemaglutideTirzepatideGonadorelinNAD+LegitScript Verified
Get StartedRead full Luvo Health review →
6.1/ 10
Verified partner

DudeMeds

Best for: compounded semaglutide at $175/month

★★★☆☆3.1/5

Editorial score · methodology

$175/mo
CompoundedSemaglutideTirzepatideNAD+
Get StartedRead full DudeMeds review →
7.8/ 10
Verified partner

Oak

Best for: semaglutide at $119/month, 37% below the typical price

★★★★☆3.9/5

Editorial score · methodology

$119/mo
CompoundedSemaglutideTirzepatideGlutathioneNAD+LegitScript Verified
Get StartedRead full Oak review →
6.4/ 10
Verified partner

Bodybuilding Health+

Best for: seeing what it charges before you answer any medical questions

★★★☆☆3.2/5

Editorial score · methodology

$179/mo
CompoundedSemaglutideTirzepatideGHK-CuGlutathioneLegitScript Verified
Get StartedRead full Bodybuilding Health+ review →
8.0/ 10
Verified partner

Lttl

Best for: starting below a standard dose, with microdose tiers

★★★★☆4/5

Editorial score · methodology

$119/mo
CompoundedSemaglutideTirzepatide
Get StartedRead full Lttl review →

Largest Cities in South Dakota

Sioux FallsRapid CityAberdeenBrookings

Frequently Asked Questions

The lowest regular prices from sellers that ship to South Dakota are $79/mo at Embody, $79/mo at Lean Meds and $79/mo at NextMeds. Half of the 145 priced sellers charge $175/mo or less.
South Dakota Medicaid does not pay for GLP-1 drugs prescribed only for weight loss. GLP-1s prescribed for type 2 diabetes are covered, with prior authorization.
Your prescriber sends the request on this paperwork: SD-specific GLP-1 Agonists Prior Authorization Request Form (footer GLP1Agonists_SouthDakotaMedicaid_2026May). Pharmacy claims run through OptumRx. The prior authorization phone line is 1-855-401-4262.
A denial can be appealed within 30 days through the SD DSS Office of Administrative Hearings (605.773.6851). A fast-track appeal is available when waiting would put your health at risk.
174, counting sellers whose published state list includes South Dakota. 128 of those list every state, and ZYP Medical is among the few that serve 15 states or fewer. For comparison, Iowa has 185, Minnesota has 180 and Montana has 179.
Superpower (42 states), Harmony Wellness Clinic (36 states), Mint Med (36 states), PreventiveMD (36 states), Willow (35 states) and Zealthy (34 states) publish long state lists that leave South Dakota out.
In 2025, South Dakota Medicaid paid for at least 15,521 GLP-1 prescriptions, including at least 6,787 for Ozempic and at least 7,486 for Mounjaro, about $15.7 million before manufacturer rebates. Drugs labeled for weight loss made up 0% of that spending.
South Dakota has 67 practices in the federal provider registry that list obesity medicine, endocrinology or bariatric care, 7.25 per 100,000 residents (37th of 51). By specialty: 35 bariatric, 31 endocrinology and 1 obesity medicine. About 37% of adults here had obesity in 2024 (CDC), the 11th-highest rate of the 50 states and DC. Measured against the median state, South Dakota has 1.27 times as much adult obesity per specialist practice.

Rankings: semaglutide providers · tirzepatide providers · clinical-trial results · GLP-1 pipeline

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