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Tirzepatide in South Dakota: Prices & Providers (2026)

139 tirzepatide sellers list South Dakota as a shipping state. The lowest regular price among them is $104/mo, and South Dakota Medicaid does not cover weight loss.

139 of the 176 tirzepatide sellers that publish a state list include South Dakota, the 39th-most of the 50 states and DC. 99 of them ship to all 50 states, and 1 serves 15 states or fewer. Across the 126 with a regular monthly price, the middle figure is $249/mo.

South Dakota Medicaid does not pay for GLP-1 drugs prescribed only for weight loss. GLP-1s prescribed for type 2 diabetes are covered, with prior authorization.

Featured Partners · South Dakota

Featured Tirzepatide providers serving South Dakota

Some of the links on this page earn us money. If you sign up with a provider after following one, that provider may pay GLP Watchdog a commission. Learn more

  1. Top pick
    8.7

    Tirzepatide from

    $149/mo

    Save $937/mo vs Zepbound
    Get started →
  2. Tirzepatide from

    $149/mo

    Save $937/mo vs Zepbound
    Get started →
  3. Tirzepatide from

    $125/mo

    Save $961/mo vs Zepbound
    Get started →
  4. Tirzepatide from

    $139/mo

    Save $947/mo vs Zepbound
    Get started →
  5. Tirzepatide from

    $269/mo

    Save $817/mo vs Zepbound
    Get started →
  6. Tirzepatide from

    $199/mo

    Save $887/mo vs Zepbound
    Get started →

Some of the links on this page earn us money. If you sign up with a provider after following one, that provider may pay GLP Watchdog a commission. Learn more

Who Ships Tirzepatide to South Dakota

  1. Lavender Sky Health $104/mo
  2. Lean Meds $109/mo
  3. NextMeds $109/mo

Lowest regular tirzepatide prices for South Dakota: Lavender Sky Health at $104/mo, Lean Meds at $109/mo and NextMeds at $109/mo. Brand-name Zepbound lists at $1,086/mo without insurance, $982 more than the lowest.

Smaller-footprint sellers that include South Dakota: ZYP Medical (6 states).

7 sellers that list 30 or more states leave South Dakota off, among them Harmony Wellness Clinic, Mint Med, PreventiveMD, Willow and Zealthy.

Seller counts next door: Iowa 148, Minnesota 143, Montana 143, North Dakota 138, Nebraska 143 and Wyoming 142.

For semaglutide, 155 sellers list South Dakota, starting at $79/mo with Embody.

Every Tirzepatide Provider Serving South Dakota

9.3/ 10
Verified partner

Embody

Best for: knowing which pharmacy fills the vial: it names RedRock Pharmacy

★★★★★4.7/5

Editorial score · methodology

$79/mo
CompoundedSemaglutideTirzepatideGlutathioneNAD+
Get StartedRead full Embody review →
9.0/ 10
Verified partner

Live Vital

Best for: semaglutide at $99/month, 48% below the typical price

★★★★★4.5/5

Editorial score · methodology

$99/mo
CompoundedSemaglutideTirzepatideRetatrutideBPC-157
Get StartedRead full Live Vital review →
8.6/ 10
Verified partner

Found

Best for: tirzepatide at $169/month, 37% below the typical price

★★★★☆4.3/5

Editorial score · methodology

$99/mo
CompoundedSemaglutideTirzepatideOrforglipron
Get StartedRead full Found review →
8.4/ 10
Verified partner

Enhance MD

Best for: knowing which pharmacy fills the vial: it names Tru Meds Rx

★★★★☆4.2/5

Editorial score · methodology

$112/mo
CompoundedSemaglutideTirzepatideNAD+
Get StartedRead full Enhance MD review →
6.7/ 10
Verified partner

Eden

Best for: coverage in all 50 states, which most sellers will not confirm

★★★☆☆3.4/5

Editorial score · methodology

$189/mo
CompoundedSemaglutideTirzepatideGHK-CuGlutathioneFDA Warning
Get StartedRead full Eden review →
Open the full A–Z list of 139 Tirzepatide providers in South Dakota

What Tirzepatide Costs in South Dakota

Brand-name Zepbound lists at $1,086/mo without insurance.

ProviderPriceBelow Zepbound list
Lavender Sky Health$104/mo$982/mo less
Lean Meds$109/mo$977/mo less
NextMeds$109/mo$977/mo less
Trimi Health$125/mo$961/mo less
Embody$129/mo$957/mo less
Jyra Health$133/mo$953/mo less
bmiMD$139/mo$947/mo less
Fresh Day Meds$140/mo$946/mo less
NewSelf$144/mo$942/mo less
Alan Meds$145/mo$941/mo less
Mondae$145/mo$941/mo less
Aspire Health$149/mo$937/mo less
CoreAge Rx$149/mo$937/mo less
Gala$149/mo$937/mo less
Nalena$149/mo$937/mo less
Vitara RX$149/mo$937/mo less
Gimme Care$163/mo$923/mo less
Big Easy Weight Loss$166/mo$920/mo less
BioGlow Health$169/mo$917/mo less
Enhance MD$169/mo$917/mo less
Found$169/mo$917/mo less
Bon Health$170/mo$916/mo less
AmberHealth$175/mo$911/mo less
Luma Health Co$180/mo$906/mo less
EverSlim$183/mo$903/mo less
Live Vital$183/mo$903/mo less
SurpassMD$184/mo$902/mo less
Navio MD$189/mo$897/mo less
Rewinding RX$191.76/mo$894.24/mo less
Trava Health$198/mo$888/mo less
Care Bare Rx$199/mo$887/mo less
Curex$199/mo$887/mo less
DoctorAdam$199/mo$887/mo less
He & She MD$199/mo$887/mo less
InstaRX$199/mo$887/mo less
Pepti$199/mo$887/mo less
Piper$199/mo$887/mo less
Precision Telemed$199/mo$887/mo less
Rivo Health$199/mo$887/mo less
Sprout Health$199/mo$887/mo less
StackMD$199/mo$887/mo less
Strut Health$199/mo$887/mo less
Trellis Vitality$199/mo$887/mo less
Trinity Meds$199/mo$887/mo less
Zera Health$199/mo$887/mo less
Vytora Health$200/mo$886/mo less
Invyncible$210/mo$876/mo less
YourHealthRx$210/mo$876/mo less
LifespanningRx$212.50/mo$873.50/mo less
Curve$225/mo$861/mo less
Nouri$225/mo$861/mo less
Kongo$229/mo$857/mo less
ZYP Medical$233/mo$853/mo less
DreamHug Medical$238/mo$848/mo less
Coby Health$239/mo$847/mo less
Vaylen$239/mo$847/mo less
Effecty$240/mo$846/mo less
PepHaūs$246/mo$840/mo less
altRX$249/mo$837/mo less
Bionomy Health$249/mo$837/mo less
GOAL.MD$249/mo$837/mo less
NuBloom$249/mo$837/mo less
PlexusDx$249/mo$837/mo less
Revel Health$249/mo$837/mo less
Rylo Health$249/mo$837/mo less
Tyde Wellness$249/mo$837/mo less
Rebody Health$249.99/mo$836.01/mo less
Medsol RX$250/mo$836/mo less
NP2GO$250/mo$836/mo less
ReadyRx$255/mo$831/mo less
Yucca Health$258/mo$828/mo less
FMmeds$265/mo$821/mo less
REMEVi$269/mo$817/mo less
Renlo Health$269/mo$817/mo less
LifeRx.md$275/mo$811/mo less
Welling Health$275/mo$811/mo less
AVARA Rx$279/mo$807/mo less
Rx.com$285/mo$801/mo less
Amble$289/mo$797/mo less
Brightmeds$289/mo$797/mo less
EOS Health$289/mo$797/mo less
Fierce Health$297/mo$789/mo less
Ivy Rx$297/mo$789/mo less
TMates$297/mo$789/mo less
AskRx$299/mo$787/mo less
BetterMe Rx$299/mo$787/mo less
EdgeRx$299/mo$787/mo less
Get Thin MD$299/mo$787/mo less
GoodRx$299/mo$787/mo less
Heally$299/mo$787/mo less
HealthSource$299/mo$787/mo less
Hers$299/mo$787/mo less
Hims$299/mo$787/mo less
KERNX Health$299/mo$787/mo less
Longevixx$299/mo$787/mo less
Medro$299/mo$787/mo less
NiceRx$299/mo$787/mo less
Pallas Health$299/mo$787/mo less
Semaglutide Online$299/mo$787/mo less
TeleClinic$299/mo$787/mo less
Zappy Health$299/mo$787/mo less
Rixa Health$304.38/mo$781.62/mo less
The Edit$309/mo$777/mo less
RxSpan MD$329/mo$757/mo less
Fitish$339/mo$747/mo less
Eden$349/mo$737/mo less
Knownwell$349/mo$737/mo less
Peak Wellness$349/mo$737/mo less
Rex MD$349/mo$737/mo less
Synergy Rx$349/mo$737/mo less
Wellorithm$349/mo$737/mo less
Maximus$359.99/mo$726.01/mo less
Independent Wellness$379/mo$707/mo less
Tryozi$379/mo$707/mo less
Apex MD$399/mo$687/mo less
Aspen$399/mo$687/mo less
Breeze Meds$399/mo$687/mo less
Joey Med$399/mo$687/mo less
PlushCare$399/mo$687/mo less
Remedy Meds$399/mo$687/mo less
RestorLife Med$399/mo$687/mo less
TeleCareSpot$399/mo$687/mo less
Revive Meds$459/mo$627/mo less
VirtualCare2Go$629/mo$457/mo less
Levity$1,299/mo
Form Health$1,350/mo
Auren RxSee review
Belle Health$199/mo prepaid
Cora Health$135/mo prepaid
Elara Health and Wellness$196/mo prepaid
MEDViSee review
Mochi HealthSee review
MyFastRx$149/mo prepaid
Ondra Health$166/mo prepaid
PeterMD$249/mo prepaid
Trillium Meds$199/mo prepaid
Vita BellaSee review
WeightWatchers ClinicSee review
WispSee review

South Dakota Medicaid and Zepbound

South Dakota Medicaid does not pay for GLP-1 drugs prescribed only for weight loss. GLP-1s prescribed for type 2 diabetes are covered, with prior authorization.

Prior authorization
Prior authorization formSD-specific GLP-1 Agonists Prior Authorization Request Form (footer GLP1Agonists_SouthDakotaMedicaid_2026May)
Prior authorization phone1-855-401-4262
Prior authorization fax1-844-403-1029
Urgent decisionwithin 72 hours
Pharmacy benefit managerOptumRx
Enrollmentabout 136,919 people (October 2025)
If the request is denied
Time to file an appeal30 days
Appeals officeSD DSS Office of Administrative Hearings
Appeals phone605.773.6851
Rule that governs itSD Medicaid Reconsideration Reviews Manual (Feb 2025)
Fast-track appealavailable when waiting would put your health at risk
“Most PA requests are adjudicated within 72 hours. A 'clean' request is often adjudicated in less than 24 hours.”
SD Medicaid Pharmacy Services Billing & Policy Manual (December 2025) page 5

In 2025, South Dakota Medicaid paid for at least 7,486 tirzepatide prescriptions, including at least 7,486 for Mounjaro, about $7.8 million before manufacturer rebates.

Medicaid rules checked May 2026. Prescription counts: CMS State Drug Utilization Data. Check your eligibility

Largest Cities in South Dakota

Sioux FallsRapid CityAberdeenBrookings

Frequently Asked Questions

The lowest regular prices from sellers that ship to South Dakota are $104/mo at Lavender Sky Health, $109/mo at Lean Meds and $109/mo at NextMeds. Half of the 126 priced sellers charge $249/mo or less. Brand-name Zepbound lists at $1,086/mo before insurance.
South Dakota Medicaid does not pay for GLP-1 drugs prescribed only for weight loss. GLP-1s prescribed for type 2 diabetes are covered, with prior authorization.
Your prescriber sends the request on this paperwork: SD-specific GLP-1 Agonists Prior Authorization Request Form (footer GLP1Agonists_SouthDakotaMedicaid_2026May). Pharmacy claims run through OptumRx. The prior authorization phone line is 1-855-401-4262.
A denial can be appealed within 30 days through the SD DSS Office of Administrative Hearings (605.773.6851). A fast-track appeal is available when waiting would put your health at risk.
139, counting sellers whose published state list includes South Dakota. 99 of those list every state, and ZYP Medical is among the few that serve 15 states or fewer. For comparison, Iowa has 148, Minnesota has 143 and Montana has 143.
Harmony Wellness Clinic (36 states), Mint Med (36 states), PreventiveMD (36 states), Willow (35 states), Zealthy (34 states) and Care Clinics (32 states) publish long state lists that leave South Dakota out.
In 2025, South Dakota Medicaid paid for at least 7,486 tirzepatide prescriptions, including at least 7,486 for Mounjaro, about $7.8 million before manufacturer rebates.
The lowest regular tirzepatide price for South Dakota is $104/mo (Lavender Sky Health); for semaglutide it is $79/mo (Embody). 139 sellers list South Dakota for tirzepatide and 155 for semaglutide.

Glossary

The words sellers use, defined. Tap any term.

Keep Reading

Tirzepatide in neighboring states: