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Riovie Review

Semaglutide & tirzepatide GLP-1 weight-loss telehealth · Independently scored 8.5/10

Best for: people who want posted prices for compounded semaglutide or tirzepatide as a shot or a sublingual tablet

8.5
★★★★☆8.5/10

Riovie scores highest on the clinical side (which drugs it prescribes and how it doses) and lowest on follow-up care. It charges from $115 a month, paid up front; its compounded semaglutide, at $149, is 25% below the $199 median among the sellers we compare.

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$115/mo

charged as a multi-month plan up front

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Not stated

Coaching

Not stated

See plans →

Prices checked November 2026

Compare top-rated alternatives ↓

Riovie is an online clinic that prescribes compounded semaglutide and tirzepatide as a weekly injection or a daily under-the-tongue tablet, alongside menopause hormone therapy and longevity treatments such as sermorelin, NAD+ and glutathione. It names its medical group and its compounding pharmacy and publishes its state list. Injectable semaglutide is $149 for one month or $345 for a 3-month plan; tirzepatide is $209 or $585.

By Ruth Calder · Enforcement Editor
Editorially reviewed. Not medical advice · How we verify contentLast reviewed
Price shown up frontIncludes medication + consultAll 50 statesPharmacy namedNo FDA warning letters found

Is Riovie legit?

Yes. Riovie is a real, operating US company, and we found no FDA warning letters issued to it. We rate it 8.5/10 overall, across six areas from price to trust and safety. Legitimate is not the same as right for you, though: that part is a decision for you and a licensed clinician.

Is there a Riovie promo or coupon code?

We know of no promo or coupon code for Riovie. Its listed price is $115 a month. Coupon sites advertising "Riovie discount codes" are not a source we can vouch for, and any genuine offer shows at checkout without a code.

See how Riovie compares on our rankings of the best semaglutide providers and the best tirzepatide providers.

Vetted alternatives to Riovie

9.3/ 10
Verified partner

Embody

Best for: a flat compounded tirzepatide or semaglutide price at every dose, from a seller that names its pharmacies

★★★★★9.3/10

Editorial score · methodology

$79/mo
CompoundedSemaglutideTirzepatideGlutathioneNAD+
Get StartedRead full Embody review →
8.7/ 10
Verified partner

Eden

Best for: coverage in all 50 states, which most sellers will not confirm

★★★★☆8.7/10

Editorial score · methodology

$99/mo
CompoundedSemaglutideTirzepatideGHK-CuGlutathione
Get StartedRead full Eden review →
6.6/ 10
Verified partner

HumeCare+

Best for: an oral route if you will not self-inject

★★★☆☆6.6/10

Editorial score · methodology

$199/mo
CompoundedSemaglutideTirzepatide
Get StartedRead full HumeCare+ review →
Riovie logo
8.5 / 10
Our editorial rating
Visit Riovie →

from $115/mo · no insurance needed

Riovie at a glance

Type
GLP-1 telehealth provider
Medications
Semaglutide, Tirzepatide
Starting price
$115/mo
What's included
Medication · Consult · Shipping
Availability
All 50 states
FDA status
No FDA warning letters found

How Riovie scores

Six columns, each one computed from something Riovie has published rather than from an opinion we formed: what it charges, which molecules it will dispense, what its record shows, and what the monthly figure actually buys. Where a seller keeps something back, such as its price or its pharmacy, the score reflects it. Every seller we review goes through the same six columns.

Value25%

7.1/10

$149/month is 25% below the $199 median for compounded semaglutide across the sellers we compare. A cheaper plan paid several months up front is also listed.

Effectiveness25%

10.0/10

Dispenses semaglutide and tirzepatide, compounded only. Anchored to SURMOUNT-1 (tirzepatide, -20.9%) and STEP 1 (semaglutide, -14.9%).

User Experience15%

8.0/10

A price is shown before the questionnaire starts.

Trust & Safety15%

9.0/10

It names the pharmacy that fills its prescriptions. It shows a price before asking for health information. It lists the states it serves.

Accessibility10%

10.0/10

Serves all 50 states.

Support10%

7.0/10

The price covers the medication, clinician visits and shipping.

6weighted dimensions
734sellers compared
Everychecked against the seller's own site
Value 25%Effectiveness 25%User Experience 15%Trust & Safety 15%Accessibility 10%Support 10%

A seller that shows no price until after the medical intake loses points on User Experience and Trust & Safety, and its review says so. How we score →

What we checked on Riovie

Last checked November 2026
  • Checked the listed price across 8 dose or plan tiers
  • Checked state coverage: all 50
  • Checked what the monthly price covers, and what it leaves out
  • Recorded which pharmacies the seller names as filling its prescriptions, with the page and date
  • Checked FDA warning letters for Riovie

Price, availability, and compliance here are read off the seller's own pages and off primary regulatory records, named in the sources below.

What signing up with Riovie involves

What to expect on the way to a prescription: where the price appears, who fills the medication, and what the monthly price covers. It is not medical advice, and a clinician makes the prescribing decision.

  1. 1Riovie shows a price on its own site before asking anything about you, so you can compare it with other sellers before you start a questionnaire.
  2. 2VialsRX fills the prescriptions, and Riovie names it publicly, which most sellers do not.
  3. 3The monthly price includes the medication, clinician visits and shipping.
Price shown before you start
  • Lowest ongoing monthly price: semaglutide $115, tirzepatide $195. That leaves out membership fees, first-month rates and insurance copays.
  • Riovie serves all 50 states.
  • The medication is compounded, so it is not an FDA-approved product and has not been reviewed by the agency for safety, effectiveness or manufacturing quality.

Contacting Riovie

Email
Riovie offers email support

Cancelling Riovie

Taken from the terms Riovie publishes. Terms change, so check the current policy before you subscribe.

Cancel any time
Yes
Minimum commitment
Month-to-month or a 3-month term; both renew automatically, and the terms also describe a 6-month plan the site does not price
Refund policy
Refund policy: "once a charge processes, that charge is final" except for medical disqualification or a pharmacy error; "Medication fees are non-refundable once the medication is dispensed or shipped."

Medications Riovie lists

Riovie lists compounded semaglutide and compounded tirzepatide. Each one has its own guide: how it works, the dosing schedule, the side effects that show up in practice, and what the trials measured.

Semaglutide(compounded)Tirzepatide(compounded)

Peptides Riovie offers

Riovie sells peptides beyond the GLP-1s. Tap one to read what the evidence says about it.

DropletGlutathioneAntioxidant infusionsDropletNAD+Energy & cellular agingHeartPT-141Desire & arousalSyringeSermorelinOwn growth-hormone output

Pricing

Prices re-verified

Weekly injection, month-to-month planCompounded
$149/mo
semaglutide

Injection price table: Semaglutide 1 month $149. Plain, B12 and glycine versions are listed at the same price.

Weekly injection, 3-month plan ($345 per 3-month term)Compounded
$115/mo
semaglutide

Injection price table: Semaglutide 3 month $345, per month $115. The terms describe a 3-month term that renews into another 3-month term, and the fee for a term that has begun is non-refundable.

Weekly injection, month-to-month planCompounded
$209/mo
tirzepatide

Injection price table: Tirzepatide 1 month $209. Plain, B12 and glycine versions are listed at the same price.

Weekly injection, 3-month plan ($585 per 3-month term)Compounded
$195/mo
tirzepatide

Injection price table: Tirzepatide 3 month $585, per month $195.

Daily sublingual tablet, month-to-month planCompounded
$209/mo
semaglutide

Tablet price table: Semaglutide 1 month $209.

Daily sublingual tablet, 3-month plan ($585 per 3-month term)Compounded
$195/mo
semaglutide

Tablet price table: Semaglutide 3 month $585, per month $195.

Daily sublingual tablet, month-to-month planCompounded
$259/mo
tirzepatide

Tablet price table: Tirzepatide 1 month $259.

Daily sublingual tablet, 3-month plan ($687 per 3-month term)Compounded
$229/mo
tirzepatide

Tablet price table: Tirzepatide 3 month $687, per month $229.

Check the price yourself before you pay

Every figure here comes from Riovie's own website, as of the date shown. Sellers move prices without announcing it, and promotional rates lapse, so confirm the standing cost on their site before committing.

See Riovie pricing →

Riovie compounding-pharmacy partners

Riovie names each pharmacy below as one that compounds or fills its prescriptions, in its own site, terms or filings. The quote under each one is the seller’s own wording.

VialsRX

License footprint
1 states: TX
“Prescriptions are filled by licensed pharmacies within the Riovie Pharmacy Network. Our partner pharmacy is: VialsRX 6220 Westpark Dr, Houston, TX 77057 Phone: (713) 497-5590”

Compare every compounding pharmacy we’ve reviewed →

In its favor

  • Semaglutide costs $149 a month, 25% below the $199 median for compounded semaglutide across the sellers we compare
  • Tirzepatide costs $209 a month, 22% below the $269 median for compounded tirzepatide across the sellers we compare
  • Shows its price before the medical questionnaire, so you can compare it without handing over health information
  • The monthly price includes the medication, clinician visits and shipping
  • Serves all 50 states
  • Names VialsRX as the pharmacy that fills its prescriptions, which most sellers do not
  • We found no FDA warning letters issued to Riovie

Against it

  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

What Riovie charges

Riovie lists $115/month.

  • Compounded semaglutide (injection, monthly): $149/month
  • Compounded semaglutide (injection, 3-month plan): $115/month
  • Compounded tirzepatide (injection, monthly): $209/month
  • Compounded tirzepatide (injection, 3-month plan): $195/month
  • Compounded semaglutide (sublingual, monthly): $209/month
  • Compounded semaglutide (sublingual, 3-month plan): $195/month

For compounded semaglutide, the median across the sellers we compare is $199/month, so Riovie's $149 is genuinely below the middle, not just advertised that way. Some of Riovie's plans are paid several months up front, so read the terms you agree to at checkout before you choose a longer one.

bmiMD, at about $129/month, is the closest like-for-like alternative we review.

What Riovie dispenses

Riovie prescribes semaglutide (approved as Wegovy and Ozempic) and tirzepatide (approved as Zepbound and Mounjaro). Between them these are the two molecules with the largest published weight-loss trial programs behind them. These are compounded preparations from a licensed pharmacy rather than approved pens, which is where the lower price comes from. A compounded drug is not FDA-approved as a finished product: the specific preparation has not been reviewed for safety, efficacy or manufacturing quality. For what differs besides the price, see compounded semaglutide vs Ozempic and Wegovy.

A needle-free oral option is genuinely uncommon and is the reason some readers will look at Riovie at all. Set expectations on the evidence, though: the published weight-loss trials for these molecules used injections. Oral and sublingual delivery of peptides is far less studied, so treat it as a route that solves the needle problem rather than as a proven equal to the shot. No human absorption study of sublingual semaglutide drops has been published.

Safety and disclosure

Riovie tells you its price before you start the medical questionnaire, that it treats patients in all 50 states, and the pharmacy that fills its prescriptions. We found no FDA warning letters issued to Riovie. Because the medication is compounded, the named pharmacy is the detail that matters most: its license is the one you can look up. The FDA publishes seven warning signs for telehealth medicine sellers, and they take a minute to run against Riovie. How we weigh oversight, disclosure and price is set out in our scoring methodology.

Riovie also sells NAD+, and a 2026 systematic review found no outcomes trials of injected NAD+ for anti-aging or wellness.

Who should look elsewhere

  • You want the FDA-approved pen specifically. Everything listed here is compounded.
  • You need insurance to cover the cost. Check whether Riovie bills your plan before you start.

It fits if

  • the lowest standing monthly cost is what you are solving for
  • injections are the thing keeping you from starting
  • you need access wherever you live

Our read

Riovie competes on price without an obvious sacrifice elsewhere: $149/month for compounded semaglutide, no FDA warning letters, and wide state coverage.

The Bottom Line

Riovie scores highest on the clinical side (which drugs it prescribes and how it doses) and lowest on follow-up care. It charges from $115 a month, paid up front; its compounded semaglutide, at $149, is 25% below the $199 median among the sellers we compare.

Score: 8.5/10Best for: people who want posted prices for compounded semaglutide or tirzepatide as a shot or a sublingual tabletFrom: $115/mo

Before you pay Riovie

Starting at $115 a month. Check today's price, then start the intake.

Visit Riovie →

Where Riovie is the wrong choice

No seller suits every reader, and pretending otherwise is the easiest way to sell one. On these three counts, another seller does better.

  • If you need the FDA-approved pen rather than a compounded vial, consider WellMedRx.
  • If the standing monthly cost is what decides it, consider Collective (from $59/mo + membership).
  • If you want a human checking in, not just a prescription, consider Eden.

If none of these fits, our guide to alternatives to Riovie sets more sellers in the same category beside Riovie on price, states and what the price includes.

Frequently Asked Questions

Riovie is an online clinic that prescribes compounded semaglutide and tirzepatide as a weekly injection or a daily under-the-tongue tablet, alongside menopause hormone therapy and longevity treatments such as sermorelin, NAD+ and glutathione. It names its medical group and its compounding pharmacy and publishes its state list. Injectable semaglutide is $149 for one month or $345 for a 3-month plan; tirzepatide is $209 or $585. We rate it 8.5/10 overall.
Riovie starts at $115 a month. The pricing table above lists every tier.
Riovie says it treats patients in all 50 states.
Riovie lists compounded semaglutide and compounded tirzepatide. A needle-free oral form is listed as well.
Riovie lists compounded GLP-1s only. A licensed compounding pharmacy prepares them: same active ingredient as the brand drug, lower cash price, and no FDA approval of the finished product. That last part is the one readers underestimate, and the review above says why.
Check whether Riovie bills your insurance before you sign up. Compounded GLP-1s are rarely covered by insurance, so plan on paying the listed cash price.
Riovie says the price covers medication, the clinician visit and shipping. The strip near the top of this review shows what is included and what is not.
You fill in an online intake, a licensed clinician decides whether a GLP-1 is appropriate, and if the answer is yes the medication ships to you. Riovie runs that whole sequence on its own site.
We found no FDA warning letters issued to Riovie. Before you buy, weigh these: Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality. None of them rules Riovie out, but each is worth settling before you pay.
Other sellers we cover include bmiMD, Live Vital, and Oak. Which one fits depends on the medication, the monthly price you can sustain and whether it ships to your state, so compare those three facts before you switch.

How to check Riovie yourself

Every seller that ships to your state, side by side: Alabama, Alaska, Florida, Michigan, Missouri, Nebraska, New Hampshire, South Carolina and every other state.

Glossary

The words sellers use, defined. Tap any term.

Sources

Cited across this Riovie review: primary regulatory filings, and peer-reviewed studies.

Sources & methodology — as of November 2026
  1. 1.GLP Watchdog — GLP-1 Pricing Index 2026 (our independent dataset)— GLP Watchdog.
  2. 2.FDA — Compounding and the 503A Pharmacy Framework— U.S. Food & Drug Administration.
  3. 3.FDA — Drug Shortages Database (current shortage listings)— U.S. Food & Drug Administration.
  4. 4.PCAB — Pharmacy Compounding Accreditation Board Standards— Accreditation Commission for Health Care (ACHC) / PCAB.
  5. 5.KFF — Medicaid coverage research (anti-obesity & GLP-1 drug policy)— Kaiser Family Foundation.
  6. 6.STEP 1 Trial — Once-Weekly Semaglutide in Adults with Overweight or Obesity (Wilding JPH et al.)— New England Journal of Medicine.PMID: 33567185.
  7. 7.FDA — Wegovy (semaglutide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
  8. 8.FDA — Ozempic (semaglutide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
  9. 9.SURMOUNT-1 Trial — Tirzepatide Once Weekly for the Treatment of Obesity (Jastreboff AM et al.)— New England Journal of Medicine.PMID: 35658024.
  10. 10.FDA — Zepbound (tirzepatide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
  11. 11.FDA — Mounjaro (tirzepatide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
  12. 12.SURMOUNT-5 Trial — Tirzepatide vs. Semaglutide Head-to-Head in Obesity (Aronne LJ et al.)— New England Journal of Medicine.PMID: 40353578.

See Riovie's current pricing

Plans start at $115 a month. Whether you qualify is a clinician's decision, made after your intake.

Visit Riovie →