One80Rx Review
GLP-1 weight-loss telehealth · Independently scored 4.1/10
Best for: shoppers who will confirm the monthly price during the consultation before committing
One80Rx falls below our bar on disclosure. Read the breakdown below before you give it money.
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Covered by the plan
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
Prices checked October 2026
One80Rx is a Tampa-based telehealth platform offering compounded semaglutide and tirzepatide, a microdose plan and an oral GLP-1 alongside a long peptide menu. It advertises GLP-1 programs "from $129/mo" as a new-patient offer, but each treatment page says the price is available by consultation, so the ongoing monthly cost is not published. Billing runs every 30 days, and the company names neither its medical group nor its pharmacy.
Is One80Rx legit?
Yes. One80Rx is a real, operating US company, and we found no FDA warning letters issued to it. We rate it 4.1/10 overall, across six areas from price to trust and safety. Legitimate is not the same as right for you, though: that part is a decision for you and a licensed clinician.
Is there an One80Rx promo or coupon code?
We know of no promo or coupon code for One80Rx. Coupon sites advertising "One80Rx discount codes" are not a source we can vouch for, and any genuine offer shows at checkout without a code.
See how One80Rx compares on our rankings of the best weight-loss injection providers.
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One80Rx at a glance
- Type
- GLP-1 telehealth provider
- Medications
- Semaglutide, Tirzepatide
- What's included
- Medication · Consult · Shipping
- FDA status
- No FDA warning letters found
How One80Rx scores
Six columns, each one computed from something One80Rx has published rather than from an opinion we formed: what it charges, which molecules it will dispense, what its record shows, and what the monthly figure actually buys. Where a seller keeps something back, such as its price or its pharmacy, the score reflects it. Every seller we review goes through the same six columns.
Value25%
3.0/10There is no monthly price to compare, so Value is capped rather than scored against other sellers.
Effectiveness25%
5.0/10No medication list or price is available to score, so this is held at the midpoint. It is not a judgment on the drugs themselves.
User Experience15%
3.0/10No price appears until the medical intake is finished.
Trust & Safety15%
4.0/10No pharmacy is named for its prescriptions. Its price appears only after the medical intake.
Accessibility10%
5.0/10No state list is available to check, so this is held at the midpoint rather than scored on reach.
Support10%
5.0/10No published price, so what a price would include cannot be assessed. Held at the midpoint.
A seller that shows no price until after the medical intake loses points on User Experience and Trust & Safety, and its review says so. How we score →
What we checked on One80Rx
Last checked October 2026- Checked what the monthly price covers, and what it leaves out
- Checked FDA warning letters for One80Rx
Price, availability, and compliance here are read off the seller's own pages and off primary regulatory records, named in the sources below.
What signing up with One80Rx involves
What to expect on the way to a prescription: where the price appears, who fills the medication, and what the monthly price covers. It is not medical advice, and a clinician makes the prescribing decision.
- 1One80Rx shows a price only after you finish its medical questionnaire, so you cannot compare costs until you have shared health information.
- 2Ask One80Rx which pharmacy fills the prescription before you pay. The pharmacy's name is what lets you check its license.
- 3The monthly price includes the medication, clinician visits and shipping.
- Before you commit, get the ongoing monthly price of the medication itself, not a first-month rate, a membership fee or a per-vial price.
- Confirm that One80Rx serves your state before you start.
Contacting One80Rx
- Phone
- (813) 303-0607
- One80Rx offers email support
- Hours
- Monday to Friday, 9:00 AM to 5:00 PM
Cancelling One80Rx
Taken from the terms One80Rx publishes. Terms change, so check the current policy before you subscribe.
- Minimum commitment
- Recurring charge every 30 days; the FAQ says memberships need 30 days' notice before the next billing cycle
- Refund policy
- Refunds only for a wrong or damaged product, a product failing safety standards, an unshipped order, or a declined prescription
GLP-1 medications One80Rx offers
Each one has its own guide: how the molecule works, the dosing schedule, the side effects that show up in practice, and what the trials actually measured.
In its favor
- The monthly price includes the medication, clinician visits and shipping
- We found no FDA warning letters issued to One80Rx
Against it
- You only see a price after finishing the medical intake, so you cannot compare costs before sharing health information
- Confirm it serves your state before you start the intake
- Ask which pharmacy fills the prescription before you pay, so you can check its license
What One80Rx charges
There is no standard monthly price to quote for One80Rx, so you cannot compare it with other sellers until you have been through an intake and received a quote. When you get one, ask for the ongoing monthly figure and what it includes, not the first-month rate and not a program total divided by its length.
What One80Rx dispenses
One80Rx prescribes semaglutide (approved as Wegovy and Ozempic) and tirzepatide (approved as Zepbound and Mounjaro). Between them these are the two best-evidenced weight-loss molecules currently on the market.
A needle-free oral option is genuinely uncommon and is the reason some readers will look at One80Rx at all. Set expectations on the evidence, though: the published weight-loss trials for these molecules used injections. Oral and sublingual delivery of peptides is far less studied, so treat it as a route that solves the needle problem rather than as a proven equal to the shot.
Safety and disclosure
Before you start an intake, ask One80Rx which states it serves, which pharmacy fills its prescriptions and what the monthly price includes. We found no FDA warning letters issued to One80Rx. How we weigh oversight, disclosure and price is set out in our scoring methodology.
Who should look elsewhere
- You want to compare prices before spending time on an intake. There is no standard monthly price to compare.
- You need insurance to cover the cost. Check whether One80Rx bills your plan before you start.
It fits if
- injections are the thing keeping you from starting
Our read
Whether One80Rx is priced well is impossible to judge before an intake, because there is no standard price to compare. That does not rule it out, and plenty of legitimate sellers quote after intake, but it puts the comparison after you have spent the time, which is the wrong order for you as the buyer. Collective is the nearest comparison we review, and worth reading alongside this.
The Bottom Line
One80Rx falls below our bar on disclosure. Read the breakdown below before you give it money.
Before you pay One80Rx
Check today's price, then start the intake.
Where One80Rx is the wrong choice
No seller suits every reader, and pretending otherwise is the easiest way to sell one. On these two counts, another seller does better.
- If you need the FDA-approved pen rather than a compounded vial, consider Sesame Care.
- If you want a human checking in, not just a prescription, consider ShedRx.
Compare One80Rx head to head
The sellers closest to One80Rx on medication and price.
Frequently Asked Questions
Glossary
The words sellers use, defined. Tap any term.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Sources
Cited across this One80Rx review: primary regulatory filings, and peer-reviewed studies.
Sources & methodology — as of October 2026
- 1.GLP Watchdog — GLP-1 Pricing Index 2026 (our independent dataset)— GLP Watchdog.
- 2.FDA — Compounding and the 503A Pharmacy Framework— U.S. Food & Drug Administration.
- 3.FDA — Drug Shortages Database (current shortage listings)— U.S. Food & Drug Administration.
- 4.PCAB — Pharmacy Compounding Accreditation Board Standards— Accreditation Commission for Health Care (ACHC) / PCAB.
- 5.KFF — Medicaid coverage research (anti-obesity & GLP-1 drug policy)— Kaiser Family Foundation.
See One80Rx's current pricing
Whether you qualify is a clinician's decision, made after your intake.