TMates Review
Semaglutide & tirzepatide GLP-1 weight-loss telehealth · Independently scored 7.8/10
Best for: coaching inside the $249/month rather than sold separately
TMates scores highest on the clinical side (which drugs it prescribes and how it doses) and lowest on price. It charges from $249 a month; its compounded tirzepatide, at $297, is 10% above the $269 median among the sellers we compare.
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Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
In the price
Prices checked October 2026
TMates is a Miami-based telehealth platform selling compounded semaglutide at $249/mo and compounded tirzepatide at $297/mo, the same price at every dose, injectable or oral. The model is messaging-first, with independent licensed prescribers and unnamed third-party compounding pharmacies. It says it reaches all 50 states.
Is TMates legit?
Yes. TMates is a real, operating US company, and we found no FDA warning letters issued to it. We rate it 7.8/10 overall, across six areas from price to trust and safety. Legitimate is not the same as right for you, though: that part is a decision for you and a licensed clinician.
Is there a TMates promo or coupon code?
TMates has no code to type in. The current offer: the weight-loss program is discounted to $199/month (regularly $299/month). It applies at checkout on its own. Coupon sites advertising a "TMates promo code" are not a source we can vouch for.
See how TMates compares on our rankings of the best semaglutide providers and the best tirzepatide providers.
Vetted alternatives to TMates
Collective
Best for: flat any-dose pricing, if you can absorb a $199 annual membership on top
Editorial score · methodology
Embody
Best for: a flat compounded tirzepatide or semaglutide price at every dose, from a seller that names its pharmacies
Editorial score · methodology
Luvo Health
Best for: moving between compounded and brand without changing seller
Editorial score · methodology
TMates at a glance
- Type
- GLP-1 telehealth provider
- Medications
- Semaglutide, Tirzepatide
- Starting price
- $249/mo
- Pricing model
- Flat: the price stays the same as the dose goes up
- What's included
- Medication · Consult · Shipping · Coaching
- Availability
- All 50 states
- FDA status
- No FDA warning letters found
How TMates scores
Six columns, each one computed from something TMates has published rather than from an opinion we formed: what it charges, which molecules it will dispense, what its record shows, and what the monthly figure actually buys. Where a seller keeps something back, such as its price or its pharmacy, the score reflects it. Every seller we review goes through the same six columns.
Value25%
4.3/10$297/month is 10% above the $269 median for compounded tirzepatide across the sellers we compare.
Effectiveness25%
10.0/10Dispenses semaglutide and tirzepatide, compounded only. Anchored to SURMOUNT-1 (tirzepatide, -20.9%) and STEP 1 (semaglutide, -14.9%).
User Experience15%
8.0/10A price is shown before the questionnaire starts.
Trust & Safety15%
7.5/10No pharmacy is named for its prescriptions. It shows a price before asking for health information. It lists the states it serves.
Accessibility10%
10.0/10Serves all 50 states.
Support10%
8.5/10The price covers the medication, clinician visits, shipping and coaching.
A seller that shows no price until after the medical intake loses points on User Experience and Trust & Safety, and its review says so. How we score →
What we checked on TMates
Last checked October 2026- Checked the listed price across 2 dose or plan tiers
- Checked state coverage: all 50
- Checked what the monthly price covers, and what it leaves out
- Checked FDA warning letters for TMates
Price, availability, and compliance here are read off the seller's own pages and off primary regulatory records, named in the sources below.
What signing up with TMates involves
What to expect on the way to a prescription: where the price appears, who fills the medication, and what the monthly price covers. It is not medical advice, and a clinician makes the prescribing decision.
- 1TMates shows a price on its own site before asking anything about you, so you can compare it with other sellers before you start a questionnaire.
- 2Ask TMates which pharmacy fills the prescription before you pay. The pharmacy's name is what lets you check its license.
- 3The monthly price includes the medication, clinician visits, shipping and coaching.
- Lowest ongoing monthly price: semaglutide $249, tirzepatide $297. That leaves out membership fees, first-month rates and insurance copays.
- TMates serves all 50 states.
- The medication is compounded, so it is not an FDA-approved product and has not been reviewed by the agency for safety, effectiveness or manufacturing quality.
Cancelling TMates
Taken from the terms TMates publishes. Terms change, so check the current policy before you subscribe.
- Cancel any time
- Yes
- Minimum commitment
- None
- Refund policy
- Not published by the seller
Medications TMates lists
TMates lists compounded semaglutide and compounded tirzepatide. Each one has its own guide: how it works, the dosing schedule, the side effects that show up in practice, and what the trials measured.
Pricing
Prices re-verified
1 month $249; 3 months $217/mo ($650, save 13%); 6 months $175/mo ($1,050, save 30%); 12 months $158/mo ($1,900, save 37%). Injectable or oral at the same price. Includes medication and ongoing support, free shipping, cancel anytime.
1 month $297; 3 months $267/mo ($800, save 10%); 6 months $217/mo ($1,299, save 27%); 12 months $167/mo ($1,999, save 44%). Injectable or oral at the same price.
Check the price yourself before you pay
Every figure here comes from TMates's own website, as of the date shown. Sellers move prices without announcing it, and promotional rates lapse, so confirm the standing cost on their site before committing.
In its favor
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- The monthly price stays the same as your dose goes up
- The monthly price includes the medication, clinician visits, shipping and coaching
- Serves all 50 states
- We found no FDA warning letters issued to TMates
Against it
- Semaglutide costs $249 a month, 25% above the $199 median for compounded semaglutide across the sellers we compare
- Tirzepatide costs $297 a month, 10% above the $269 median for compounded tirzepatide across the sellers we compare
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
What TMates charges
The standing price at TMates is $249/month, unchanged as the dose goes up. Flat dose pricing matters more than it sounds: on a tiered plan the bill grows with the dose, so the figure that got you to sign up is not the one you end up paying.
- Compounded semaglutide: $249/month
- Compounded tirzepatide: $297/month
For compounded tirzepatide, the median across the sellers we compare is $269/month, so TMates' $297 lands mid-market. Price is unlikely to be the deciding factor. Before you pay, compare TMates' cancellation terms with other sellers' cancellation and refund policies.
Wellorithm dispenses semaglutide and tirzepatide from $247/month, which makes it the fair comparison to run before you commit here.
What TMates dispenses
TMates prescribes semaglutide (approved as Wegovy and Ozempic) and tirzepatide (approved as Zepbound and Mounjaro). Between them these are the two best-evidenced weight-loss molecules currently on the market. These are compounded preparations from a licensed pharmacy rather than approved pens, which is where the lower price comes from. A compounded drug is not FDA-approved as a finished product: the specific preparation has not been reviewed for safety, efficacy or manufacturing quality. For what differs besides the price, see compounded semaglutide vs Ozempic and Wegovy.
Safety and disclosure
TMates tells you its price before you start the medical questionnaire and that it treats patients in all 50 states. It also offers coaching as part of the plan. We found no FDA warning letters issued to TMates. Because the medication is compounded, the most useful question to ask at intake is which licensed pharmacy fills the prescription. If TMates will not tell you, treat that as a warning sign. Once you have the pharmacy's name, 503A vs 503B explains which regulator oversees it and how to check. How we weigh oversight, disclosure and price is set out in our scoring methodology.
Who should look elsewhere
- You want the FDA-approved pen specifically. Everything listed here is compounded.
- You need insurance to cover the cost. Check whether TMates bills your plan before you start.
It fits if
- you want the price to stop moving as your dose climbs
- you want coaching bundled in rather than billed on top
- you need access wherever you live
Our read
TMates lands mid-market on price without a standout advantage or an obvious problem. It comes down to whether its particular package fits you. Direct Meds is the nearest comparison we review, and worth reading alongside this.
The Bottom Line
TMates scores highest on the clinical side (which drugs it prescribes and how it doses) and lowest on price. It charges from $249 a month; its compounded tirzepatide, at $297, is 10% above the $269 median among the sellers we compare.
Before you pay TMates
Starting at $249 a month. Check today's price, then start the intake.
Where TMates is the wrong choice
No seller suits every reader, and pretending otherwise is the easiest way to sell one. On these two counts, another seller does better.
- If you need the FDA-approved pen rather than a compounded vial, consider WellMedRx.
- If the standing monthly cost is what decides it, consider Collective (from $59/mo + membership).
If none of these fits, our guide to alternatives to TMates sets more sellers in the same category beside TMates on price, states and what the price includes.
Frequently Asked Questions
How to check TMates yourself
- Buying Tirzepatide as a Research Chemical: What "Research Use Only" Really Means
- How to Get a GLP-1 Prescription
- FDA Warning Letters to Peptide Sellers: What FDA Has Cited, 2023 to 2026
Every seller that ships to your state, side by side: Connecticut, Delaware, Florida, Kansas, Oklahoma, Texas, West Virginia, Wisconsin and every other state.
Glossary
The words sellers use, defined. Tap any term.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Sources
Cited across this TMates review: primary regulatory filings, and peer-reviewed studies.
Sources & methodology — as of October 2026
- 1.GLP Watchdog — GLP-1 Pricing Index 2026 (our independent dataset)— GLP Watchdog.
- 2.FDA — Compounding and the 503A Pharmacy Framework— U.S. Food & Drug Administration.
- 3.FDA — Drug Shortages Database (current shortage listings)— U.S. Food & Drug Administration.
- 4.PCAB — Pharmacy Compounding Accreditation Board Standards— Accreditation Commission for Health Care (ACHC) / PCAB.
- 5.KFF — Medicaid coverage research (anti-obesity & GLP-1 drug policy)— Kaiser Family Foundation.
- 6.STEP 1 Trial — Once-Weekly Semaglutide in Adults with Overweight or Obesity (Wilding JPH et al.)— New England Journal of Medicine.PMID: 33567185.
- 7.FDA — Wegovy (semaglutide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
- 8.FDA — Ozempic (semaglutide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
- 9.SURMOUNT-1 Trial — Tirzepatide Once Weekly for the Treatment of Obesity (Jastreboff AM et al.)— New England Journal of Medicine.PMID: 35658024.
- 10.FDA — Zepbound (tirzepatide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
- 11.FDA — Mounjaro (tirzepatide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
- 12.SURMOUNT-5 Trial — Tirzepatide vs. Semaglutide Head-to-Head in Obesity (Aronne LJ et al.)— New England Journal of Medicine.PMID: 40353578.
See TMates's current pricing
Plans start at $249 a month. Whether you qualify is a clinician's decision, made after your intake.