PlushCare Review
Semaglutide & tirzepatide GLP-1 weight-loss telehealth · Independently scored 6.4/10
Best for: coverage in all 50 states, which most of the register will not confirm
PlushCare's strongest column is the clinical side — which molecules it will prescribe, and how it handles dosing.
Covered by the monthly price
Medication
Charged on top
Clinician visits
Charged on top
Shipping
Not stated
Lab work
Charged on top
Coaching
Not stated
No insurance needed · Vetted by our editors
PlushCare is an established virtual primary-care telehealth platform and a subsidiary of Transcarent, Inc., a Delaware corporation that also owns Accolade, 2nd.MD, and 98point6 by Transcarent. Virtual visits with US board-certified physicians cost $30 per appointment insured and $129 self-pay. GLP-1 prescribing is a clinician-discretionary option within the broader primary-care relationship.
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Vetted alternatives to PlushCare
Editorial score · methodology
Editorial score · methodology
Editorial score · methodology
PlushCare at a glance
- Type
- GLP-1 telehealth provider
- Medications
- Wegovy, Ozempic, Zepbound, Mounjaro
- Starting price
- $149/mo (Range up to $299/mo)
- Availability
- All 50 states
- FDA status
- No FDA warning letter on record
How PlushCare scores
Six columns, each one computed from something PlushCare has published rather than from an opinion we formed: what it charges, which molecules it will dispense, what its record shows, and what the monthly figure actually buys. Where it publishes nothing, that absence is what gets scored. Every seller in the register goes through the same six columns.
Value25%
3.0/10The figures published here are not comparable monthly cash prices for the medication — an insured copay, a per-vial rate, a membership fee or a starting-dose teaser. Capped rather than scored against the register.
Effectiveness25%
10.0/10Dispenses semaglutide and tirzepatide, compounded only. Anchored to SURMOUNT-1 (tirzepatide, -20.9%) and STEP 1 (semaglutide, -14.9%).
User Experience15%
7.0/10On the seller's own pages, a price is published before the questionnaire starts; a live video visit is required, which is slower but is the more careful intake; baseline bloodwork is required before a prescription.
Trust & Safety15%
7.5/10does not name a dispensing pharmacy; shows a price before asking for health information; publishes its state list. Our verification confidence is medium.
Accessibility10%
10.0/10Publishes coverage in 50 of 50 states.
Support10%
0.0/10States explicitly that the price covers none of medication, consult, shipping, labs or coaching.
A seller that will not show a price before an intake loses points on Value and carries that note in its review. Withholding the number is itself a finding. How we score →
What we checked on PlushCare
Last checked July 2026- Re-read the price on file across 2 dose or plan tiers
- Checked state coverage: all 50
- Established what the monthly figure covers, and what it leaves out
- Searched our FDA enforcement register for this operator
Price, availability, and compliance here are read off the seller's own pages and off primary regulatory records, named in the sources below. Editorial confidence in this data: medium.
What signing up with PlushCare involves
Assembled from this seller’s entry in the register — the price record, the state list, the dispensing pharmacy where one is named, and what the monthly figure covers. It describes what a reader can expect to meet on the way to a prescription, and what is missing from the seller’s own disclosures. It is not a clinical judgment and not a prescribing decision.
- 1PlushCare publishes a price on its own site before asking anything about you. You can compare it against this register without starting a questionnaire.
- 2The intake requires a live video visit with a clinician and baseline bloodwork, which is more than most of the register asks and slower to complete.
- 3PlushCare does not say which pharmacy dispenses the medication. That is common here and it means you cannot check the pharmacy's record before you buy.
- No comparable monthly cash price for the medication is on record — either nothing is published, or what is published is a fee, an insured copay or a per-vial rate rather than a monthly cost.
- Coverage is published for all 50 states.
PlushCare support, as documented
- Phone
- 1-888-729-0438
- info@plushcare.com
GLP-1 medications PlushCare offers
Each one has its own guide: how the molecule works, the dosing schedule, the side effects that show up in practice, and what the trials actually measured.
Pricing
Prices re-verified
Range up to $299/mo
Range up to $599/mo
Check the price yourself before you pay
Every figure here was read off PlushCare's own checkout on the date shown. Sellers move prices without announcing it, and promotional rates lapse, so confirm the standing cost on their site before committing.
In its favor
- Publishes a price on its own site before the medical questionnaire, so it can be compared without handing over health information
- Coverage is published for all 50 states
- No FDA warning letter matched this operator when we searched our enforcement register
- A live video visit with a clinician is required before a prescription, which is slower than a form and is the more careful intake
- Baseline bloodwork is required before a prescription
Against it
- Billed separately from the monthly figure: medication, consult, labs
- No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
What PlushCare charges
PlushCare charges $149/month. That sits at the affordable end of what we track.
- Compounded semaglutide — $149/month
- Compounded tirzepatide — $399/month
Across the GLP-1 providers in our register the median standing price is about $169/month, so PlushCare is genuinely under the middle rather than merely advertising that it is.
Found, at about $149/month, is the closest thing we track to a like-for-like alternative.
What PlushCare dispenses
PlushCare prescribes semaglutide (approved as Wegovy and Ozempic) and tirzepatide (approved as Zepbound and Mounjaro). Between them these are the pair carrying the strongest published outcome data. What arrives is compounded at a licensed pharmacy, not an approved pen. That is the reason it costs less, and the reason the finished preparation carries no FDA review behind it.
What we could verify
On the record: it treats patients in all 50 states. We searched the federal warning-letter record for this operator and came back with nothing. Because the medication is compounded and no dispensing pharmacy is named publicly, the single most useful question to ask at intake is which licensed pharmacy fills the prescription. A seller that will not answer that has told you something. How we weigh oversight, disclosure and price evidence is set out in our scoring methodology.
Who should look elsewhere
- You want the FDA-approved pen specifically. Nothing here is the approved finished product.
- You need to bill insurance. Like most of this market, this is cash-pay.
It fits if
- the lowest standing monthly cost is what you are solving for
- you need access regardless of where you live
Our read
PlushCare competes on price and does it without an obvious sacrifice elsewhere: $149/month, no warning letter on file, and access that is not unusually restricted.
The Bottom Line
PlushCare's strongest column is the clinical side — which molecules it will prescribe, and how it handles dosing.
Before you pay PlushCare
Starting at $149/month. Check today's price, then book the free consultation.
Where PlushCare is the wrong choice
No seller in this register suits every reader, and saying otherwise would be the easiest way to sell one. On these four counts another entry does better.
Frequently Asked Questions
Glossary
The words sellers use, defined. Tap any term.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Sources
Cited across this PlushCare review: primary regulatory filings, and peer-reviewed studies.
Sources & methodology — as of August 2026
- 1.GLP Watchdog — GLP-1 Pricing Index 2026 (our independent dataset)— GLP Watchdog.
- 2.FDA — Compounding and the 503A Pharmacy Framework— U.S. Food & Drug Administration.
- 3.FDA — Drug Shortages Database (current shortage listings)— U.S. Food & Drug Administration.
- 4.PCAB — Pharmacy Compounding Accreditation Board Standards— Accreditation Commission for Health Care (ACHC) / PCAB.
- 5.KFF — Medicaid coverage research (anti-obesity & GLP-1 drug policy)— Kaiser Family Foundation.
- 6.STEP 1 Trial — Once-Weekly Semaglutide in Adults with Overweight or Obesity (Wilding JPH et al.)— New England Journal of Medicine.PMID: 33567185.
- 7.FDA — Wegovy (semaglutide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
- 8.FDA — Ozempic (semaglutide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
- 9.SURMOUNT-1 Trial — Tirzepatide Once Weekly for the Treatment of Obesity (Jastreboff AM et al.)— New England Journal of Medicine.PMID: 35658024.
- 10.FDA — Zepbound (tirzepatide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
- 11.FDA — Mounjaro (tirzepatide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
- 12.SURMOUNT-5 Trial — Tirzepatide vs. Semaglutide Head-to-Head in Obesity (Garvey WT et al.)— New England Journal of Medicine.PMID: 40334173.
See PlushCare's current pricing
Plans start at $149/month. The free consultation is where you learn whether you qualify, and what it costs today.