GLP Watchdog

PlushCare vs Polly

Neither PlushCare nor Polly has an FDA warning letter on record. On compounded tirzepatide injection, Polly costs $1,440 less a year at standing rates: $279 a month against $399 a month at PlushCare. It is one of two products the two sell at comparable terms.

To see where both sit among the other sellers, read our best weight-loss injection providers board.

By Ruth Calder · Enforcement Editor
Editorially reviewed. Not medical advice · How we verify contentLast reviewed

The record

PlushCare / Polly

PlushCare logo

PlushCare

6.4/10

Polly logo

Polly

8.4/10

FDA warning letters
None on record
None on record
Pharmacy
None named in our record
Lowest standing price
$149/moCompounded semaglutide injection
$179/moCompounded semaglutide injection
States
All 50 states
All 50 states
Checked
Prices captured Record checked September 2026
Prices captured Record checked November 2026
Visit PlushCare
Visit Polly

Neither PlushCare nor Polly pays us. Links to them earn nothing. Scores: PlushCare 6.4, Polly 8.4. How we are paid

What the record shows

  1. 01

    Neither PlushCare nor Polly has an FDA warning letter on record.

  2. 02

    Polly names two pharmacies, all 503A. PlushCare names no compounding pharmacy in our record.

  3. 03

    On compounded tirzepatide injection, Polly costs $1,440 less a year at standing rates: $279 a month against $399 a month at PlushCare. It is one of two products the two sell at comparable terms.

  4. 04

    PlushCare states you can cancel at any time; Polly does not state its cancellation terms.

Prices and terms, product by product

A price is set against the other side only for the same product, and only when both are standing monthly or 4-week rates. Those pairs are compared by yearly cost.

PlushCare

Polly

Compounded semaglutide injection

$149/moLower

$1,788 a year

$179/mo

$2,148 a year

Compounded tirzepatide injection

$399/mo

$4,788 a year

$279/moLower

$3,348 a year

Price includes
Not stated
Medication, clinician visits, shipping
Billed separately
Medication, clinician visits, labs
Not stated
Cancel any time
Yes, stated
Not stated
Minimum term
None; membership is billed monthly or annually
Month to month, or a 3- or 6-month supply charged at checkout
Refunds
Appointment cost only; membership fees and prescriptions are not refunded
Full refund only before the medical intake is submitted; 3- and 6-month plans cannot be refunded once the first month has passed
Early-exit fee
Not stated
Yes

Read off each seller’s own pages. PlushCare: July 10, 2026. Polly: October 17, 2026. Every plan and dose we hold is on the full review.

The case for each

The case for PlushCare

6.4/10
  • $360 a year less on compounded semaglutide injection
  • States you can cancel at any time
  • Names no compounding pharmacy
  • Price leaves out medication, clinician visits and labs
Visit PlushCare

The case for Polly

8.4/10
  • $1,440 a year less on compounded tirzepatide injection
  • Names its compounding pharmacy
  • Price includes clinician visits
Visit Polly

Scores

PlushCare 6.4 · Polly 8.4 out of 10. Six weighted parts.

Value25%

3.0A
vs
B
5.8

Effectiveness25%

10.0A
vs
B
10.0

User Experience15%

7.0A
vs
B
8.0

Trust & Safety15%

7.5A
vs
B
10.0

Accessibility10%

10.0A
vs
B
10.0

Support10%

0.0A
vs
B
7.0

The score is the same formula for every seller. Payment does not enter it. Method

PlushCare vs Polly: questions

Neither PlushCare nor Polly has an FDA warning letter on record. Letters are matched to a seller by company, domain and address, never by a similar name.
Polly names two pharmacies, all 503A. PlushCare names no compounding pharmacy in our record. A 503A pharmacy compounds for named patients on a prescription; a 503B outsourcing facility is registered with FDA and inspected under federal manufacturing rules.
PlushCare, by $360 a year at standing rates. PlushCare: $149 a month, about $1,788 a year. Polly: $179 a month, about $2,148 a year.
PlushCare states you can cancel at any time; refunds: appointment cost only; membership fees and prescriptions are not refunded. Polly does not state its cancellation terms.
Neither PlushCare nor Polly pays us. Links to them earn nothing. Scores: PlushCare 6.4, Polly 8.4.

Other sellers we are paid by

Affiliate partners outside this pair. Each has its own record and review, scored the same way.

Sellers closest to these two

Matched on molecule, form and price. Every pair we list · The register