Mechanism

GLP-1 receptor

What a GLP-1 receptor agonist actually does: which receptors it reaches, how it slows gastric emptying, and the satiety pathway it runs through.

What is GLP-1 receptor?

The G-protein coupled receptor that responds to glucagon-like peptide-1.

Activating it suppresses appetite, slows gastric emptying and improves glucose-dependent insulin secretion. Every drug in this register works on it; what differs is what else they touch.

GLP Watchdog writes these definitions from FDA labels and peer-reviewed PubMed literature.

Where GLP-1 receptor comes up on this site

On GLP Watchdog, GLP-1 receptor comes up in 3 FDA warning letters and 2 tools. Browse the FDA warning letters.

Other terms under Mechanism

Where the evidence lives