Amylin
What a GLP-1 receptor agonist actually does: which receptors it reaches, how it slows gastric emptying, and the satiety pathway it runs through.
What is Amylin?
A pancreatic hormone co-secreted with insulin that signals fullness through the brainstem, a different pathway from GLP-1 entirely.
Long-acting analogs such as cagrilintide are being tested alone and stacked with semaglutide to push weight loss past what GLP-1 alone reaches.
GLP Watchdog writes these definitions from FDA labels and peer-reviewed PubMed literature.
Where Amylin comes up on this site
On GLP Watchdog, Amylin comes up in 1 FDA warning letter. Browse the FDA warning letters.
Connected terms
Other terms under Mechanism
- GLP-1 receptor
- GIP receptor
- Dual agonist
- Gastric emptying
- Food noise
- Triple agonist
- GLP-1 tachyphylaxis
- Non-peptide GLP-1 agonist
- A1C (glycated hemoglobin)
- MASH / MASLD
- TBWL (Total Body Weight Loss)
- C-peptide
- eGFR (estimated glomerular filtration rate)
- Visceral adipose tissue (VAT)
- AHI (apnea-hypopnea index)
- SNAC (oral semaglutide absorption enhancer)
Where the evidence lives
- The full GLP-1 glossary (149 terms, 8 categories)
- Research articles — written from primary sources
- Tools and calculators
- Compare GLP-1 telehealth providers