AHI (apnea-hypopnea index)
What a GLP-1 receptor agonist actually does: which receptors it reaches, how it slows gastric emptying, and the satiety pathway it runs through.
What is AHI (apnea-hypopnea index)?
Apnea-hypopnea index: breathing pauses of ten seconds or more, plus partial reductions with oxygen desaturation, counted per hour of sleep.
5–14 is mild obstructive sleep apnea, 15–29 moderate, 30 or more severe. SURMOUNT-OSA used it as the primary endpoint and tirzepatide 15 mg cut it by about 25 events an hour against placebo.
SURMOUNT-OSA trial deep-dive →
GLP Watchdog writes these definitions from FDA labels and peer-reviewed PubMed literature.
Where AHI (apnea-hypopnea index) comes up on this site
Connected terms
Other terms under Mechanism
- GLP-1 receptor
- GIP receptor
- Dual agonist
- Gastric emptying
- Food noise
- Triple agonist
- Amylin
- GLP-1 tachyphylaxis
- Non-peptide GLP-1 agonist
- A1C (glycated hemoglobin)
- MASH / MASLD
- TBWL (Total Body Weight Loss)
- C-peptide
- eGFR (estimated glomerular filtration rate)
- Visceral adipose tissue (VAT)
- SNAC (oral semaglutide absorption enhancer)
Where the evidence lives
- SURMOUNT-OSA trial deep-dive
- The full GLP-1 glossary (149 terms, 8 categories)
- Research articles — written from primary sources
- Tools and calculators
- Compare GLP-1 telehealth providers