Price and states served both move. Read them off the seller's own site before you enroll.How our reviews work →
Semaglutide in South Dakota: Prices & Providers (2026)
155 semaglutide sellers list South Dakota as a shipping state. The lowest regular price among them is $79/mo, and South Dakota Medicaid does not cover weight loss.
155 of the 204 semaglutide sellers that publish a state list include South Dakota, the 39th-most of the 50 states and DC. 112 of them ship to all 50 states, and 1 serves 15 states or fewer. Across the 136 with a regular monthly price, the middle figure is $179/mo.
South Dakota Medicaid does not pay for GLP-1 drugs prescribed only for weight loss. GLP-1s prescribed for type 2 diabetes are covered, with prior authorization.
Featured Partners · South Dakota
Featured Semaglutide providers serving South Dakota
No insurance needed
reader-supported
Some of the links on this page earn us money. If you sign up with a provider after following one, that provider may pay GLP Watchdog a commission. Learn more
- Top pick8.7Get started →Save $1,220/mo vs Wegovy
Semaglutide from
$129/mo
- 9.0Get started →Save $1,250/mo vs Wegovy
Semaglutide from
$99/mo
- 9.4Get started →Save $1,250/mo vs Wegovy
Semaglutide from
$99/mo
- 9.0Get started →Save $1,250/mo vs Wegovy
Semaglutide from
$99/mo
- 6.7Get started →Save $1,170/mo vs Wegovy
Semaglutide from
$179/mo
- 8.4Get started →Save $1,250/mo vs Wegovy
Semaglutide from
$99/mo
| Provider | Semaglutide from | Save vs Wegovy | |
|---|---|---|---|
8.7GalaTop pick | $129/mo | Save $1,220/mo | Get started → |
9.0CoreAge Rx | $99/mo | Save $1,250/mo | Get started → |
9.4Trimi Health | $99/mo | Save $1,250/mo | Get started → |
9.0bmiMD | $99/mo | Save $1,250/mo | Get started → |
6.7RxSpan MD | $179/mo | Save $1,170/mo | Get started → |
8.4Strut Health | $99/mo | Save $1,250/mo | Get started → |
Some of the links on this page earn us money. If you sign up with a provider after following one, that provider may pay GLP Watchdog a commission. Learn more
Who Ships Semaglutide to South Dakota
Lowest regular semaglutide prices for South Dakota: Embody at $79/mo, Lean Meds at $79/mo and NextMeds at $79/mo. Brand-name Wegovy lists at $1,349/mo without insurance, $1,270 more than the lowest.
Smaller-footprint sellers that include South Dakota: ZYP Medical (6 states).
8 sellers that list 30 or more states leave South Dakota off, among them Superpower, Harmony Wellness Clinic, Mint Med, PreventiveMD and Willow.
Seller counts next door: Iowa 165, Minnesota 160, Montana 160, North Dakota 154, Nebraska 160 and Wyoming 158.
For tirzepatide, 139 sellers list South Dakota, starting at $104/mo with Lavender Sky Health.
Every Semaglutide Provider Serving South Dakota
9.3/ 10
Verified partnerEmbody
Best for: knowing which pharmacy fills the vial: it names RedRock Pharmacy
★★★★★4.7/5
Editorial score · methodology
$79/mo
CompoundedSemaglutideTirzepatideGlutathioneNAD+
Get StartedRead full Embody review →★★★★★4.5/5
Editorial score · methodology
$99/mo
CompoundedSemaglutideTirzepatideRetatrutideBPC-157
Get StartedRead full Live Vital review →★★★★☆4.3/5
Editorial score · methodology
$99/mo
CompoundedSemaglutideTirzepatideOrforglipron
Get StartedRead full Found review →8.4/ 10
Verified partnerEnhance MD
Best for: knowing which pharmacy fills the vial: it names Tru Meds Rx
★★★★☆4.2/5
Editorial score · methodology
$112/mo
CompoundedSemaglutideTirzepatideNAD+
Get StartedRead full Enhance MD review →★★★☆☆3.4/5
Editorial score · methodology
$189/mo
CompoundedSemaglutideTirzepatideGHK-CuGlutathioneFDA Warning
Get StartedRead full Eden review →Open the full A–Z list of 155 Semaglutide providers in South Dakota
- Alan Meds
- Allara Health
- altRX
- AmberHealth
- Amble
- Apex MD
- AskRx
- Aspen
- Aspire Health
- Auren Rx
- AVARA Rx
- Belle Health
- BetterMe Rx
- Big Easy Weight Loss
- BioGlow Health
- Bionomy Health
- bmiMD
- Bon Health
- Breeze Meds
- Brello Health
- Brightmeds
- Calibrate Health
- Call-On-Doc
- Care Bare Rx
- Coby Health
- Cora Health
- CoreAge Rx
- Cost Plus Drugs
- Curex
- Curve
- DoctorAdam
- Dr. Gillis' Wellness Center
- DreamHug Medical
- Eden
- EdgeRx
- Effecty
- Elara Health and Wellness
- Embody
- eMI Aesthetics
- Enhance MD
- EOS Health
- EverSlim
- Fidelity Medical Clinic
- Fierce Health
- Fitish
- FitRx
- FMmeds
- Form Health
- Found
- Fresh Day Meds
- Gala
- Get Thin MD
- Gimme Care
- GOAL.MD
- He & She MD
- Heally
- HealthSource
- Hers
- Hims
- Independent Wellness
- InstaRX
- Invyncible
- Ivologist
- Ivy Rx
- Joey Med
- Jyra Health
- KERNX Health
- Kongo
- Lavender Sky Health
- Lean Meds
- Lemonaid Health
- Levity
- LifeRx.md
- LifespanningRx
- Live Vital
- Longevixx
- Luma Health Co
- Marek Health
- Maves
- Maximus
- Medro
- Medsol RX
- MEDVi
- Mochi Health
- Mondae
- MyFastRx
- Nalena
- Navio MD
- NewSelf
- Next Vial
- NextMeds
- NiceRx
- Nouri
- NovoCare Pharmacy
- NP2GO
- NuBloom
- Ondra Health
- Pallas Health
- Peak Wellness
- PepHaūs
- Pepti
- PeterMD
- Piper
- PlexusDx
- PlushCare
- Precision Telemed
- Queen RX
- ReadyRx
- Rebody Health
- Remedy Meds
- REMEVi
- Renlo Health
- RestorLife Med
- Revel Health
- Revive Meds
- Rewinding RX
- Rex MD
- Rivo Health
- Rixa Health
- Rx.com
- RxSpan MD
- Rylo Health
- Semaglutide Online
- Sprout Health
- StackMD
- Strut Health
- SurpassMD
- Synergy Rx
- TeleCareSpot
- TeleClinic
- Tell Her Doc
- The Edit
- TMates
- Trava Health
- Trellis Vitality
- Trillium Meds
- Trimi Health
- Trinity Meds
- Tryozi
- Tyde Wellness
- Vaylen
- VirtualCare2Go
- Vita Bella
- Vitara RX
- Vytora Health
- Walgreens Weight Management
- WeightWatchers Clinic
- Welling Health
- Wellorithm
- Wisp
- YourHealthRx
- Yucca Health
- Zappy Health
- Zera Health
- ZYP Medical
What Semaglutide Costs in South Dakota
Brand-name Wegovy lists at $1,349/mo without insurance.
| Provider | Price | Below Wegovy list |
|---|---|---|
| Embody | $79/mo | $1,270/mo less |
| Lean Meds | $79/mo | $1,270/mo less |
| NextMeds | $79/mo | $1,270/mo less |
| Lavender Sky Health | $95/mo | $1,254/mo less |
| Alan Meds | $99/mo | $1,250/mo less |
| bmiMD | $99/mo | $1,250/mo less |
| CoreAge Rx | $99/mo | $1,250/mo less |
| Fidelity Medical Clinic | $99/mo | $1,250/mo less |
| Fresh Day Meds | $99/mo | $1,250/mo less |
| Jyra Health | $99/mo | $1,250/mo less |
| Live Vital | $99/mo | $1,250/mo less |
| Pepti | $99/mo | $1,250/mo less |
| Strut Health | $99/mo | $1,250/mo less |
| Trimi Health | $99/mo | $1,250/mo less |
| Vitara RX | $99/mo | $1,250/mo less |
| AmberHealth | $100/mo | $1,249/mo less |
| NewSelf | $100/mo | $1,249/mo less |
| Aspire Health | $103/mo | $1,246/mo less |
| PeterMD | $105/mo | $1,244/mo less |
| Mondae | $115/mo | $1,234/mo less |
| Belle Health | $119/mo | $1,230/mo less |
| Kongo | $119/mo | $1,230/mo less |
| Trava Health | $119/mo | $1,230/mo less |
| Luma Health Co | $120/mo | $1,229/mo less |
| SurpassMD | $124/mo | $1,225/mo less |
| StackMD | $125/mo | $1,224/mo less |
| EverSlim | $127/mo | $1,222/mo less |
| DoctorAdam | $129/mo | $1,220/mo less |
| PlexusDx | $129/mo | $1,220/mo less |
| Zera Health | $129/mo | $1,220/mo less |
| Gimme Care | $130/mo | $1,219/mo less |
| Big Easy Weight Loss | $133/mo | $1,216/mo less |
| Piper | $135/mo | $1,214/mo less |
| Rewinding RX | $141.03/mo | $1,207.97/mo less |
| Ivologist | $145/mo | $1,204/mo less |
| Yucca Health | $146/mo | $1,203/mo less |
| altRX | $149/mo | $1,200/mo less |
| Dr. Gillis' Wellness Center | $149/mo | $1,200/mo less |
| Longevixx | $149/mo | $1,200/mo less |
| Nalena | $149/mo | $1,200/mo less |
| NovoCare Pharmacy | $149/mo | $1,200/mo less |
| NuBloom | $149/mo | $1,200/mo less |
| PlushCare | $149/mo | $1,200/mo less |
| Precision Telemed | $149/mo | $1,200/mo less |
| Rivo Health | $149/mo | $1,200/mo less |
| Rylo Health | $149/mo | $1,200/mo less |
| Sprout Health | $149/mo | $1,200/mo less |
| Trinity Meds | $149/mo | $1,200/mo less |
| Tyde Wellness | $149/mo | $1,200/mo less |
| Walgreens Weight Management | $149/mo | $1,200/mo less |
| NP2GO | $150/mo | $1,199/mo less |
| Trellis Vitality | $150/mo | $1,199/mo less |
| Vytora Health | $150/mo | $1,199/mo less |
| ZYP Medical | $150/mo | $1,199/mo less |
| PepHaūs | $152/mo | $1,197/mo less |
| Brello Health | $157.72/mo | $1,191.28/mo less |
| Coby Health | $159/mo | $1,190/mo less |
| Zappy Health | $159/mo | $1,190/mo less |
| Effecty | $160/mo | $1,189/mo less |
| Found | $169/mo | $1,180/mo less |
| Bon Health | $170/mo | $1,179/mo less |
| YourHealthRx | $170/mo | $1,179/mo less |
| Curve | $175/mo | $1,174/mo less |
| Nouri | $175/mo | $1,174/mo less |
| Rx.com | $175/mo | $1,174/mo less |
| Amble | $179/mo | $1,170/mo less |
| eMI Aesthetics | $179/mo | $1,170/mo less |
| Gala | $179/mo | $1,170/mo less |
| GOAL.MD | $179/mo | $1,170/mo less |
| ReadyRx | $179/mo | $1,170/mo less |
| Vaylen | $179/mo | $1,170/mo less |
| DreamHug Medical | $188/mo | $1,161/mo less |
| Bionomy Health | $189/mo | $1,160/mo less |
| Brightmeds | $189/mo | $1,160/mo less |
| Welling Health | $190/mo | $1,159/mo less |
| Invyncible | $192.50/mo | $1,156.50/mo less |
| Fierce Health | $197/mo | $1,152/mo less |
| Ivy Rx | $197/mo | $1,152/mo less |
| AskRx | $199/mo | $1,150/mo less |
| BetterMe Rx | $199/mo | $1,150/mo less |
| Breeze Meds | $199/mo | $1,150/mo less |
| Care Bare Rx | $199/mo | $1,150/mo less |
| Curex | $199/mo | $1,150/mo less |
| EOS Health | $199/mo | $1,150/mo less |
| Heally | $199/mo | $1,150/mo less |
| HealthSource | $199/mo | $1,150/mo less |
| Hers | $199/mo | $1,150/mo less |
| Hims | $199/mo | $1,150/mo less |
| InstaRX | $199/mo | $1,150/mo less |
| Medro | $199/mo | $1,150/mo less |
| NiceRx | $199/mo | $1,150/mo less |
| Pallas Health | $199/mo | $1,150/mo less |
| REMEVi | $199/mo | $1,150/mo less |
| Renlo Health | $199/mo | $1,150/mo less |
| Revel Health | $199/mo | $1,150/mo less |
| Semaglutide Online | $199/mo | $1,150/mo less |
| Synergy Rx | $199/mo | $1,150/mo less |
| TeleClinic | $199/mo | $1,150/mo less |
| Rebody Health | $199.99/mo | $1,149.01/mo less |
| LifeRx.md | $200/mo | $1,149/mo less |
| KERNX Health | $209/mo | $1,140/mo less |
| Medsol RX | $209/mo | $1,140/mo less |
| The Edit | $209/mo | $1,140/mo less |
| Rixa Health | $211.98/mo | $1,137.02/mo less |
| Enhance MD | $212/mo | $1,137/mo less |
| LifespanningRx | $212.50/mo | $1,136.50/mo less |
| Fitish | $219/mo | $1,130/mo less |
| FMmeds | $225/mo | $1,124/mo less |
| Wisp | $225/mo | $1,124/mo less |
| AVARA Rx | $229/mo | $1,120/mo less |
| EdgeRx | $229/mo | $1,120/mo less |
| Eden | $239/mo | $1,110/mo less |
| Wellorithm | $247/mo | $1,102/mo less |
| Independent Wellness | $249/mo | $1,100/mo less |
| MEDVi | $249/mo | $1,100/mo less |
| Peak Wellness | $249/mo | $1,100/mo less |
| RxSpan MD | $249/mo | $1,100/mo less |
| TMates | $249/mo | $1,100/mo less |
| Next Vial | $249.97/mo | $1,099.03/mo less |
| Maximus | $249.99/mo | $1,099.01/mo less |
| Tell Her Doc | $269/mo | $1,080/mo less |
| Aspen | $279/mo | $1,070/mo less |
| Cost Plus Drugs | $279/mo | $1,070/mo less |
| Joey Med | $279/mo | $1,070/mo less |
| Tryozi | $279/mo | $1,070/mo less |
| VirtualCare2Go | $279/mo | $1,070/mo less |
| Apex MD | $299/mo | $1,050/mo less |
| Marek Health | $299/mo | $1,050/mo less |
| Remedy Meds | $299/mo | $1,050/mo less |
| RestorLife Med | $299/mo | $1,050/mo less |
| TeleCareSpot | $299/mo | $1,050/mo less |
| Navio MD | $345/mo | $1,004/mo less |
| BioGlow Health | $349/mo | $1,000/mo less |
| Revive Meds | $369/mo | $980/mo less |
| Levity | $1,199/mo | $150/mo less |
| Form Health | $1,350/mo | |
| Allara Health | See review | |
| Auren Rx | See review | |
| Calibrate Health | See review | |
| Call-On-Doc | See review | |
| Cora Health | $99/mo prepaid | |
| Elara Health and Wellness | $117/mo prepaid | |
| FitRx | $151/mo prepaid | |
| Get Thin MD | $169/mo prepaid | |
| He & She MD | $99/mo prepaid | |
| Lemonaid Health | See review | |
| Maves | $99 first month | |
| Mochi Health | See review | |
| MyFastRx | $99/mo prepaid | |
| Ondra Health | $93/mo prepaid | |
| Queen RX | $100/mo prepaid | |
| Rex MD | See review | |
| Trillium Meds | $119/mo prepaid | |
| Vita Bella | See review | |
| WeightWatchers Clinic | See review |
South Dakota Medicaid and Wegovy
South Dakota Medicaid does not pay for GLP-1 drugs prescribed only for weight loss. GLP-1s prescribed for type 2 diabetes are covered, with prior authorization.
| Prior authorization form | SD-specific GLP-1 Agonists Prior Authorization Request Form (footer GLP1Agonists_SouthDakotaMedicaid_2026May) |
|---|---|
| Prior authorization phone | 1-855-401-4262 |
| Prior authorization fax | 1-844-403-1029 |
| Urgent decision | within 72 hours |
| Pharmacy benefit manager | OptumRx |
| Enrollment | about 136,919 people (October 2025) |
| Time to file an appeal | 30 days |
|---|---|
| Appeals office | SD DSS Office of Administrative Hearings |
| Appeals phone | 605.773.6851 |
| Rule that governs it | SD Medicaid Reconsideration Reviews Manual (Feb 2025) |
| Fast-track appeal | available when waiting would put your health at risk |
“Most PA requests are adjudicated within 72 hours. A 'clean' request is often adjudicated in less than 24 hours.”
In 2025, South Dakota Medicaid paid for at least 7,210 semaglutide prescriptions, including at least 6,787 for Ozempic and 423 for Rybelsus, about $7.0 million before manufacturer rebates.
Medicaid rules checked May 2026. Prescription counts: CMS State Drug Utilization Data. Check your eligibility
Largest Cities in South Dakota
Sioux FallsRapid CityAberdeenBrookings
Frequently Asked Questions
The lowest regular prices from sellers that ship to South Dakota are $79/mo at Embody, $79/mo at Lean Meds and $79/mo at NextMeds. Half of the 136 priced sellers charge $179/mo or less. Brand-name Wegovy lists at $1,349/mo before insurance.
South Dakota Medicaid does not pay for GLP-1 drugs prescribed only for weight loss. GLP-1s prescribed for type 2 diabetes are covered, with prior authorization.
Your prescriber sends the request on this paperwork: SD-specific GLP-1 Agonists Prior Authorization Request Form (footer GLP1Agonists_SouthDakotaMedicaid_2026May). Pharmacy claims run through OptumRx. The prior authorization phone line is 1-855-401-4262.
A denial can be appealed within 30 days through the SD DSS Office of Administrative Hearings (605.773.6851). A fast-track appeal is available when waiting would put your health at risk.
155, counting sellers whose published state list includes South Dakota. 112 of those list every state, and ZYP Medical is among the few that serve 15 states or fewer. For comparison, Iowa has 165, Minnesota has 160 and Montana has 160.
Superpower (42 states), Harmony Wellness Clinic (36 states), Mint Med (36 states), PreventiveMD (36 states), Willow (35 states) and Zealthy (34 states) publish long state lists that leave South Dakota out.
In 2025, South Dakota Medicaid paid for at least 7,210 semaglutide prescriptions, including at least 6,787 for Ozempic and 423 for Rybelsus, about $7.0 million before manufacturer rebates.
The lowest regular semaglutide price for South Dakota is $79/mo (Embody); for tirzepatide it is $104/mo (Lavender Sky Health). 155 sellers list South Dakota for semaglutide and 139 for tirzepatide.
Glossary
The words sellers use, defined. Tap any term.
- Wegovy · Drugs and brands
- Ozempic · Drugs and brands
- Rybelsus · Drugs and brands
- GLP-1 receptor · Mechanism
- STEP-1 · Major trials
- SELECT · Major trials
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms