PrescrYbe Review
Semaglutide GLP-1 weight-loss telehealth · Independently scored 6.6/10
Best for: shoppers who want a named prescriber network and pharmacies, plus an oral or microdose GLP-1 option
PrescrYbe rates best on simply being available where you are.
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Covered by the monthly price
Medication
Not stated
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
Prices checked October 2026
PrescrYbe is a cash-pay telehealth storefront for compounded semaglutide and tirzepatide, with OpenLoop Health clinicians prescribing and four named pharmacies filling orders. It sells a standard injection program, an oral GLP-1 and a microdose program on a monthly subscription. The site lists only starting prices, $239 for the injection, $229 for the oral and $169 for the microdose, and never says which drug each figure buys.
Is PrescrYbe legit?
Yes. PrescrYbe is a real, operating US company, and we found no FDA warning letters issued to it. We rate it 6.6/10 overall, across six areas from price to trust and safety. Legitimate is not the same as right for you, though: that part is a decision for you and a licensed clinician.
Is there a PrescrYbe promo or coupon code?
We know of no promo or coupon code for PrescrYbe. Its listed price is $169 a month. Coupon sites advertising "PrescrYbe discount codes" are not a source we can vouch for, and any genuine offer shows at checkout without a code.
See how PrescrYbe compares on our rankings of the best semaglutide providers.
Vetted alternatives to PrescrYbe
CoreAge Rx
Best for: flat-priced compounded semaglutide at $79 a month, any dose
Editorial score · methodology
Editorial score · methodology
Editorial score · methodology
PrescrYbe at a glance
- Type
- GLP-1 telehealth provider
- Medications
- Semaglutide, Tirzepatide
- Starting price
- $169/mo
- What's included
- Consult · Shipping
- Availability
- All 50 states + DC
- FDA status
- No FDA warning letters found
How PrescrYbe scores
Six columns, each one computed from something PrescrYbe has published rather than from an opinion we formed: what it charges, which molecules it will dispense, what its record shows, and what the monthly figure actually buys. Where a seller keeps something back, such as its price or its pharmacy, the score reflects it. Every seller we review goes through the same six columns.
Value25%
3.0/10The listed figure is not a comparable monthly price for a named GLP-1 (it may be a membership fee, an insured copay, a per-vial rate or a starting-dose price), so Value is capped rather than scored against other sellers.
Effectiveness25%
8.5/10Dispenses semaglutide, compounded only. Anchored to SURMOUNT-1 (tirzepatide, -20.9%) and STEP 1 (semaglutide, -14.9%).
User Experience15%
8.0/10A price is shown before the questionnaire starts.
Trust & Safety15%
7.5/10No pharmacy is named for its prescriptions. It shows a price before asking for health information. It lists the states it serves.
Accessibility10%
10.0/10Serves all 50 states and DC.
Support10%
4.0/10The price covers clinician visits and shipping.
A seller that shows no price until after the medical intake loses points on User Experience and Trust & Safety, and its review says so. How we score →
What we checked on PrescrYbe
Last checked October 2026- Checked the listed price across 3 dose or plan tiers
- Checked state coverage: all 50
- Checked what the monthly price covers, and what it leaves out
- Checked FDA warning letters for PrescrYbe
Price, availability, and compliance here are read off the seller's own pages and off primary regulatory records, named in the sources below.
What signing up with PrescrYbe involves
What to expect on the way to a prescription: where the price appears, who fills the medication, and what the monthly price covers. It is not medical advice, and a clinician makes the prescribing decision.
- 1PrescrYbe shows a price on its own site before asking anything about you, so you can compare it with other sellers before you start a questionnaire.
- 2Ask PrescrYbe which pharmacy fills the prescription before you pay. The pharmacy's name is what lets you check its license.
- 3The monthly price includes clinician visits and shipping.
- Before you commit, get the ongoing monthly price of the medication itself, not a first-month rate, a membership fee or a per-vial price.
- PrescrYbe serves all 50 states and DC.
Contacting PrescrYbe
- PrescrYbe offers email support
Cancelling PrescrYbe
Taken from the terms PrescrYbe publishes. Terms change, so check the current policy before you subscribe.
- Cancel any time
- Yes
- Minimum commitment
- Month-to-month subscription; cancel by email or the patient portal no later than 72 hours ahead of the billing date
- Refund policy
- Money back in full if you cancel in the first 72 hours before receiving any service, or if a clinician disqualifies you; otherwise the current and past months are not refunded.
- Early-termination fee
- None
Medications PrescrYbe lists
PrescrYbe lists compounded semaglutide. Each one has its own guide: how it works, the dosing schedule, the side effects that show up in practice, and what the trials measured.
Pricing
Prices re-verified
Listed as "Starting at $169" for the GLP-1 Injection Microdose program. The site does not say whether this is semaglutide or tirzepatide, or what dose it covers.
Listed as "Starting at $229" for a single-ingredient oral GLP-1. The molecule is not named.
Listed as "Starting at $239" for the GLP-1 Injection program, which the page says covers semaglutide and tirzepatide. Recorded as the semaglutide rate because it is the starting figure; the tirzepatide price is not shown.
Check the price yourself before you pay
Every figure here was read off PrescrYbe's own checkout on the date shown. Sellers move prices without announcing it, and promotional rates lapse, so confirm the standing cost on their site before committing.
In its favor
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- The monthly price includes clinician visits and shipping
- Serves all 50 states and DC
- We found no FDA warning letters issued to PrescrYbe
Against it
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- Its semaglutide is compounded rather than FDA-approved, so it has not been reviewed by the agency for safety, effectiveness or manufacturing quality
What PrescrYbe charges
The standing price at PrescrYbe is $169/month.
- Compounded semaglutide: $169/month
- Compounded semaglutide: $229/month
- Compounded semaglutide: $239/month
Enhance MD, at about $169/month, is the closest like-for-like alternative we review.
What PrescrYbe dispenses
PrescrYbe prescribes semaglutide (approved as Wegovy and Ozempic) and tirzepatide (approved as Zepbound and Mounjaro). Between them these are the two molecules with the largest published weight-loss trial programs behind them. These are compounded preparations from a licensed pharmacy rather than approved pens, which is where the lower price comes from. A compounded drug is not FDA-approved as a finished product: the specific preparation has not been reviewed for safety, efficacy or manufacturing quality.
A needle-free oral option is genuinely uncommon and is the reason some readers will look at PrescrYbe at all. Set expectations on the evidence, though: the published weight-loss trials for these molecules used injections. Oral and sublingual delivery of peptides is far less studied, so treat it as a route that solves the needle problem rather than as a proven equal to the shot.
Safety and disclosure
PrescrYbe tells you its price before you start the medical questionnaire and that it treats patients in all 50 states. We found no FDA warning letters issued to PrescrYbe. Because the medication is compounded, the most useful question to ask at intake is which licensed pharmacy fills the prescription. If PrescrYbe will not tell you, treat that as a warning sign. How we weigh oversight, disclosure and price is set out in our scoring methodology.
Who should look elsewhere
- You want the FDA-approved pen specifically. Everything listed here is compounded.
- You need insurance to cover the cost. Check whether PrescrYbe bills your plan before you start.
It fits if
- injections are the thing keeping you from starting
- you need access wherever you live
Our read
PrescrYbe charges $169/month. Too few sellers offer the same drug and form to say whether that is cheap or expensive, so judge it on what the package includes.
The Bottom Line
PrescrYbe rates best on simply being available where you are.
Before you pay PrescrYbe
Starting at $169 a month. Check today's price, then start the intake.
Where PrescrYbe is the wrong choice
No seller suits every reader, and pretending otherwise is the easiest way to sell one. On these three counts, another seller does better.
- If you need the FDA-approved pen rather than a compounded vial, consider SkinnyRx.
- If the standing monthly cost is what decides it, consider Collective (from $59/mo).
- If you want a human checking in, not just a prescription, consider ShedRx.
Compare PrescrYbe head to head
The sellers closest to PrescrYbe on medication and price.
Frequently Asked Questions
How to check PrescrYbe yourself
- How to Verify an Online GLP-1 Pharmacy: Six Public Checks
- We Read FDA's Register of Compounding Facilities. 42 of 98 Have Never Been Inspected.
- Buying Tirzepatide as a Research Chemical: What "Research Use Only" Really Means
Every seller that ships to your state, side by side: Alabama, Alaska, Arizona, Arkansas, California, Colorado, Connecticut, Delaware and every other state.
Glossary
The words sellers use, defined. Tap any term.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Sources
Cited across this PrescrYbe review: primary regulatory filings, and peer-reviewed studies.
Sources & methodology — as of October 2026
- 1.GLP Watchdog — GLP-1 Pricing Index 2026 (our independent dataset)— GLP Watchdog.
- 2.FDA — Compounding and the 503A Pharmacy Framework— U.S. Food & Drug Administration.
- 3.FDA — Drug Shortages Database (current shortage listings)— U.S. Food & Drug Administration.
- 4.PCAB — Pharmacy Compounding Accreditation Board Standards— Accreditation Commission for Health Care (ACHC) / PCAB.
- 5.KFF — Medicaid coverage research (anti-obesity & GLP-1 drug policy)— Kaiser Family Foundation.
- 6.STEP 1 Trial — Once-Weekly Semaglutide in Adults with Overweight or Obesity (Wilding JPH et al.)— New England Journal of Medicine.PMID: 33567185.
- 7.FDA — Wegovy (semaglutide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
- 8.FDA — Ozempic (semaglutide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
See PrescrYbe's current pricing
Plans start at $169 a month. Whether you qualify is a clinician's decision, made after your intake.