He & She MD logo

He & She MD Review

Semaglutide & tirzepatide GLP-1 weight-loss telehealth · Independently scored 9.2/10

Best for: starting below a standard dose, with microdose tiers

9.2
★★★★★4.6/5

He & She MD's strongest column is the clinical side: which molecules it will prescribe, and how it handles dosing.

Some of the links on this page earn us money. If you sign up with a provider after following one, that provider may pay GLP Watchdog a commission. Learn more

$99/mo

charged as a multi-month plan up front

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Not stated

Coaching

In the price

Compare top-rated alternatives ↓

GLP-1 Platinum opens at $139/month as an introductory rate on injectables, then settles at $199. That buys expedited delivery at no cost, board-certified clinicians reachable without limit, GLP-1 coaching and progress tracking inside the app, and billing only happens if a prescription is actually written. He & She MD works nationwide with doctor-prescribed compounded semaglutide and tirzepatide, injectable or oral, a microdose option, and access under brand names to Wegovy, Ozempic and Zepbound. Every state receives shipments except Louisiana. Certification is LegitScript.

By Ruth Calder · Enforcement Editor
Editorially reviewed (not clinically reviewed). Not medical advice · How we verify contentLast reviewed
Price shown up frontIncludes medication + consultAll 50 statesNo FDA warning letters found

Is He & She MD legit?

Yes. He & She MD is a real, operating US company, and we found no FDA warning letters issued to it. Its site shows LegitScript certification. We rate it 9.2/10 overall, across six areas from price to trust and safety. Legitimate is not the same as right for you, though: that part is a decision for you and a licensed clinician.

See how He & She MD compares on our rankings of the best semaglutide providers and the best tirzepatide providers.

Vetted alternatives to He & She MD

6.7/ 10
Verified partner

Eden

Best for: coverage in all 50 states, which most sellers will not confirm

★★★☆☆3.4/5

Editorial score · methodology

$189/mo
CompoundedSemaglutideTirzepatideGHK-CuGlutathioneFDA Warning
Get StartedRead full Eden review →
8.3/ 10
Verified partner

SnagRx

Best for: semaglutide at $99/month, 48% below the typical price

★★★★☆4.2/5

Editorial score · methodology

$69/mo
CompoundedSemaglutideTirzepatide
Get StartedRead full SnagRx review →
9.3/ 10
Verified partner

Embody

Best for: knowing which pharmacy fills the vial: it names RedRock Pharmacy

★★★★★4.7/5

Editorial score · methodology

$79/mo
CompoundedSemaglutideTirzepatideGlutathioneNAD+
Get StartedRead full Embody review →
He & She MD logo
4.6 / 5
Our editorial rating
Visit He & She MD →

from $99/mo · no insurance needed

He & She MD at a glance

Type
GLP-1 telehealth provider
Medications
Semaglutide, Tirzepatide
Starting price
$99/mo
What's included
Medication · Consult · Shipping · Coaching
Availability
All 50 states
FDA status
No FDA warning letters found

How He & She MD scores

Six columns, each one computed from something He & She MD has published rather than from an opinion we formed: what it charges, which molecules it will dispense, what its record shows, and what the monthly figure actually buys. Where a seller keeps something back, such as its price or its pharmacy, the score reflects it. Every seller we review goes through the same six columns.

Value25%

9.5/10

$99/month is 46% below the $185 median for compounded semaglutide across the sellers we compare. That figure is a multi-month plan paid up front, not a month-to-month rate, so the comparison flatters it.

Effectiveness25%

10.0/10

Dispenses semaglutide and tirzepatide, compounded only. Anchored to SURMOUNT-1 (tirzepatide, -20.9%) and STEP 1 (semaglutide, -14.9%).

User Experience15%

8.0/10

A price is shown before the questionnaire starts.

Trust & Safety15%

8.5/10

No pharmacy is named for its prescriptions. It shows a price before asking for health information. It lists the states it serves.

Accessibility10%

10.0/10

Serves 50 of 50 states.

Support10%

8.5/10

The price covers the medication, clinician visits, shipping and coaching.

6weighted dimensions
588sellers compared
Everychecked against the seller's own site
Value 25%Effectiveness 25%User Experience 15%Trust & Safety 15%Accessibility 10%Support 10%

A seller that shows no price until after the medical intake loses points on User Experience and Trust & Safety, and its review says so. How we score →

What we checked on He & She MD

Last checked August 2026
  • Checked the listed price across 4 dose or plan tiers
  • Checked state coverage: all 50
  • Checked what the monthly price covers, and what it leaves out
  • Checked FDA warning letters for He & She MD

Price, availability, and compliance here are read off the seller's own pages and off primary regulatory records, named in the sources below.

What signing up with He & She MD involves

What to expect on the way to a prescription: where the price appears, who fills the medication, and what the monthly price covers. It is not medical advice, and a clinician makes the prescribing decision.

  1. 1He & She MD shows a price on its own site before asking anything about you, so you can compare it with other sellers before you start a questionnaire.
  2. 2Ask He & She MD which pharmacy fills the prescription before you pay. The pharmacy's name is what lets you check its license.
  3. 3The monthly price includes the medication, clinician visits, shipping and coaching.
Price shown before you start
  • Lowest ongoing monthly price: semaglutide $99. That leaves out membership fees, first-month rates and insurance copays.
  • He & She MD serves all 50 states.
  • The medication is compounded, so it is not an FDA-approved product and has not been reviewed by the agency for safety, effectiveness or manufacturing quality.

Contacting He & She MD

Email
He & She MD offers email support

Cancelling He & She MD

Taken from the terms He & She MD publishes. Terms change, so check the current policy before you subscribe.

Refund policy
Only charged if prescribed

GLP-1 medications He & She MD offers

Each one has its own guide: how the molecule works, the dosing schedule, the side effects that show up in practice, and what the trials actually measured.

Pricing

Prices re-verified

Platinum injectable, intro (6-mo)Compounded
$139/mo
semaglutide
Platinum oral, intro (6-mo)Compounded
$199/mo
semaglutide
Injectable, 12-month prepayCompounded
$99/mo
semaglutide
StartingCompounded
$199/mo
tirzepatide

Injectable tirzepatide intro $199/mo (regular $289/mo)

Check the price yourself before you pay

Every figure here was read off He & She MD's own checkout on the date shown. Sellers move prices without announcing it, and promotional rates lapse, so confirm the standing cost on their site before committing.

See He & She MD pricing →

In its favor

  • Semaglutide costs $99 a month, 46% below the $185 median for compounded semaglutide across the sellers we compare
  • Shows its price before the medical questionnaire, so you can compare it without handing over health information
  • The monthly price includes the medication, clinician visits, shipping and coaching
  • Serves all 50 states
  • We found no FDA warning letters issued to He & She MD

Against it

  • Ask which pharmacy fills the prescription before you pay, so you can check its license
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

He & She MD: a low-entry GLP-1 program that lets you pick your format

One flexible product line, the GLP-1 Platinum program, is what this nationwide cash-pay telehealth clinic is built around. Several ways in exist, and that, rather than one rock-bottom number, is what earns the clinic a look: injectable semaglutide and tirzepatide both sell on a six-month introductory rate that steps up afterward, and an oral pill version exists for anyone who would rather avoid needles. Buying a full year up front drops the monthly figure further still. Entry pricing on that scale sits beneath the $174 category median. Nothing is charged to you unless a clinician does in fact write a prescription. For everyday patients who want to try tirzepatide, or semaglutide, without committing to a high monthly outlay up front, that is a genuinely approachable on-ramp.

What the headline prices leave out

Understand this before signing up: the headline prices are introductory rates tied to a subscription term, not the long-run cost. The injectable plan advertises its low intro price on a six-month commitment and then steps up to a higher standard monthly rate afterward. The oral tier follows the same pattern at a somewhat higher level. The lowest figure the clinic advertises is not an introductory rate at all: it is the price of buying twelve months of injectable semaglutide in one go, divided by twelve. That is the longest commitment on offer, not the easiest way in. None of this is a teaser-then-cancel trap exactly, but they are teaser rates, so budget for the post-intro price rather than the sticker on the homepage.

  • Twelve-month prepay: the lowest per-month figure advertised, and the largest sum committed up front
  • Standard injectable: the mainstream choice, intro-priced over a six-month plan
  • Oral option: a needle-free route at a modest premium over the injectable
  • Billing safeguard: nothing is billed until a prescription is written for you, and no add-on fees hide behind the rate

The medications and who fills them

Transparency is this clinic's strongest suit, and the pharmacy disclosure is why. Two FDA-registered compounders are named outright: Specialty Medical Drugstore LLC, trading as GoGoMeds, and F&F Pharmacies Inc, which operates Jungle Jims Pharmacy out of Fairfield, Ohio. Plenty of competitors never say who compounds their product; naming them puts the supply chain within your reach to check. The catalog itself runs to tirzepatide and semaglutide, compounded, as injections or in oral form, as injections or in oral form. Brand-name Zepbound, Wegovy and Ozempic are advertised too, for anyone who wants the FDA-approved finished products.

What you get besides the vial

Fees that other clinics itemize are folded into the Platinum membership. Inside the price: the medication, the clinician consultation, expedited shipping at no extra cost, coaching built around GLP-1 use with nutrition guidance, and progress tracking in the app. Clinician access is billed as unlimited. In practice that means no rationing of messages and no per-follow-up charge when a dose needs adjusting or a side effect worries you. If what you want is a prescription in the mail and nothing else, that support is dead weight. If this is your first GLP-1 and you want someone to talk to, it is a real part of what you are paying for.

Coverage and the fine print

Delivery reaches DC and 49 states. Louisiana is the single hard exclusion. PO boxes are refused everywhere, so have a street address ready. Billing is cash-pay: no insurance claim is filed on your behalf and the cost comes out of pocket. Compounded-GLP-1 telehealth works this way almost universally, so it is not a mark against the clinic, but it does matter if the plan was to run treatment through a health plan.

Trust, oversight, and the honest caveat

LegitScript certification is in place. Serious telehealth pharmacies carry it, and operations that will not survive scrutiny generally cannot clear it. We found no FDA warning letters issued to the clinic, and what it discloses about its pricing and program is specific rather than vague. Now the caveat, which the clinic states itself in its FDA disclaimer. Compounded GLP-1s are not FDA-approved finished products in the way brand Ozempic or Zepbound are. Every compounded-telehealth provider lives with that, so it is not a failing unique to this one. It does mean that if an FDA-reviewed product is what you need, the brand-name access is the route to take rather than the compounded tiers.

Who it fits, and who it does not

  • Choose it if you want the lowest-risk way to try a GLP-1, value being able to pick injectable or oral, and want coaching plus unlimited clinician access bundled in
  • Choose it if LegitScript certification and a clinic willing to name its compounding pharmacies are what you are looking for
  • Skip it if Louisiana is your state, insurance billing is a requirement, or nothing compounded will do and only FDA-approved brand medication counts
  • Skip it if you want a flat price that never changes, the intro rates rise after the first plan term

Bottom line

He & She MD earns its spot for transparency and flexibility more than for any single price. Sitting below the $174 category median on its introductory tiers, it gives needle-averse and budget-conscious patients real choices, backs them with named pharmacies and LegitScript certification, and only charges you if you are actually prescribed. Go in clear about the introductory-then-standard pricing structure and the compounded-versus-brand distinction, and confirm your current rate at checkout before you commit. For a cash-pay GLP-1 starter, it is one of the more straightforward options out there. Our scoring methodology sets out the weighting behind all of this.

Embody ($79/month) and bmiMD ($99/month) sit closest to He & She MD in what they charge and what they dispense.

The Bottom Line

He & She MD's strongest column is the clinical side: which molecules it will prescribe, and how it handles dosing.

Score: 9.2/10Best for: starting below a standard dose, with microdose tiersFrom: $99/mo

Before you pay He & She MD

Starting at $99 a month. Check today's price, then start the intake.

Where He & She MD is the wrong choice

No seller suits every reader, and pretending otherwise is the easiest way to sell one. On these two counts, another seller does better.

  • If you need the FDA-approved pen rather than a compounded vial, consider Sesame Care.
  • If the standing monthly cost is what decides it, consider Collective (from $59/mo).

Compare He & She MD head to head

The sellers closest to He & She MD on medication and price.

Frequently Asked Questions

He & She MD is a nationwide telehealth weight-loss clinic serving both men and women with doctor-prescribed GLP-1 medications. It is LegitScript-certified and offers compounded options plus brand-name access, with unlimited board-certified clinician access and in-app progress tracking.
It offers compounded semaglutide and tirzepatide in injectable or oral form plus a microdose option, along with brand-name access to Ozempic, Wegovy, and Zepbound. Compounded GLP-1s are not FDA-approved finished products, and a licensed clinician determines whether treatment is appropriate for you.
The GLP-1 Platinum program starts at $139 per month introductory for injectables (then $199), $199 per month for oral, and $99 per month for the microdose option. Introductory pricing rises after the 6-month plan (or 3-month microdose plan), and you are only charged if medication is prescribed.
He & She MD ships to 49 states, all except Louisiana, and does not ship to PO boxes. Confirm that your state is served before enrolling.
Plans include free expedited shipping, unlimited board-certified clinician access, GLP-1 coaching, nutrition guidance, and in-app progress tracking. There are no hidden fees, and it works with named FDA-registered pharmacy partners.
He & She MD operates on a cash-pay model, and insurance billing is not indicated. You are only charged once a clinician prescribes medication, with no charge if you are not prescribed.
We found no FDA warning letters issued to He & She MD. Before you buy, weigh these: Ask which pharmacy fills the prescription before you pay, so you can check its license. Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality. None of them rules He & She MD out, but each is worth settling before you pay.

Glossary

The words sellers use, defined. Tap any term.

Sources

Cited across this He & She MD review: primary regulatory filings, and peer-reviewed studies.

Sources & methodology — as of August 2026
  1. 1.GLP Watchdog — GLP-1 Pricing Index 2026 (our independent dataset)— GLP Watchdog.
  2. 2.FDA — Compounding and the 503A Pharmacy Framework— U.S. Food & Drug Administration.
  3. 3.FDA — Drug Shortages Database (current shortage listings)— U.S. Food & Drug Administration.
  4. 4.PCAB — Pharmacy Compounding Accreditation Board Standards— Accreditation Commission for Health Care (ACHC) / PCAB.
  5. 5.KFF — Medicaid coverage research (anti-obesity & GLP-1 drug policy)— Kaiser Family Foundation.
  6. 6.STEP 1 Trial — Once-Weekly Semaglutide in Adults with Overweight or Obesity (Wilding JPH et al.)— New England Journal of Medicine.PMID: 33567185.
  7. 7.FDA — Wegovy (semaglutide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
  8. 8.FDA — Ozempic (semaglutide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
  9. 9.SURMOUNT-1 Trial — Tirzepatide Once Weekly for the Treatment of Obesity (Jastreboff AM et al.)— New England Journal of Medicine.PMID: 35658024.
  10. 10.FDA — Zepbound (tirzepatide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
  11. 11.FDA — Mounjaro (tirzepatide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
  12. 12.SURMOUNT-5 Trial — Tirzepatide vs. Semaglutide Head-to-Head in Obesity (Garvey WT et al.)— New England Journal of Medicine.PMID: 40334173.

See He & She MD's current pricing

Plans start at $99 a month. Whether you qualify is a clinician's decision, made after your intake.