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TrimRx Review

Semaglutide & tirzepatide GLP-1 weight-loss telehealth · Independently scored 6.4/10

Best for: compounded semaglutide at $299/month after a $199 first month

6.4
★★★☆☆6.4/10

TrimRx scores highest on the clinical side (which drugs it prescribes and how it doses) and lowest on price. It charges from $299 a month; its compounded tirzepatide, at $399, is 48% above the $269 median among the sellers we compare.

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$199first month

then $299/mo ongoing

Same price at every dose

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Not stated

Coaching

Not stated

See plans →

Prices checked October 2026

TrimRx, based in San Diego, is a telehealth platform for compounded semaglutide and tirzepatide. Its fee holds as the dose rises and covers the consult, medication and shipping. Semaglutide is $299 a month after a $199 first month; tirzepatide is $399 after $349. It names no pharmacy and publishes no state list, and payment is taken before a clinician reviews the intake.

By Ruth Calder · Enforcement Editor
Editorially reviewed. Not medical advice · How we verify contentLast reviewed
GLP-1 from $299/moPrice shown up frontFlat across dosesIncludes medication + consultNo FDA warning letters found

What is TrimRx?

TrimRx is a San Diego telehealth platform that sells compounded semaglutide and tirzepatide by the month, with the consult, medication and shipping in one fee that does not change with the dose. Affiliated physician groups decide on the prescription after you pay, and an unnamed compounding pharmacy ships it. It suits cash payers who want a set monthly price and can live without knowing which pharmacy fills the order.

Is TrimRx legit?

Yes. TrimRx is a real, operating US company, and we found no FDA warning letters issued to it. We rate it 6.4/10 overall, across six areas from price to trust and safety. Legitimate is not the same as right for you, though: that part is a decision for you and a licensed clinician.

Is there a TrimRx promo or coupon code?

TrimRx has no coupon code to enter. New patients are currently quoted $199 for the first month, then $299 a month, and the discount applies on its own. Coupon sites advertising a "TrimRx promo code" are not a source we can vouch for.

See how TrimRx compares on our rankings of the best semaglutide providers and the best tirzepatide providers.

What customers say about TrimRx

Praised for

  • Orders arrive quickly once they ship
  • Support replies fast, and some reviewers name a helpful rep
  • Signing up or switching from another seller felt easy

Complained about

  • Hard to reach a person; replies come from an AI agent or not at all
  • Charges after canceling, surprise renewals or refunds that never arrive
  • Paid orders shipped late, or multi-month plans only partly delivered

About a third of its Trustpilot ratings are 1-star, and most recent 5-star reviews were invited by the company. BBB lists 783 complaints it says went unanswered. A summary of customer reviews on the sites linked above, read on the date shown. These are customers’ own accounts; they are not part of our score.

TrimRx logo
6.4 / 10
Our editorial rating
Visit TrimRx →

from $299/mo · no insurance needed

TrimRx at a glance

Type
GLP-1 telehealth provider
Medications
Semaglutide, Tirzepatide
Starting price
$299/mo
Pricing model
Flat: the price stays the same as the dose goes up
What's included
Medication · Consult · Shipping
FDA status
No FDA warning letters found

How TrimRx scores

Six columns, each one computed from something TrimRx has published rather than from an opinion we formed: what it charges, which molecules it will dispense, what its record shows, and what the monthly figure actually buys. Where a seller keeps something back, such as its price or its pharmacy, the score reflects it. Every seller we review goes through the same six columns.

Value25%

2.2/10

$399/month is 48% above the $269 median for compounded tirzepatide across the sellers we compare.

Effectiveness25%

10.0/10

Dispenses semaglutide and tirzepatide, including the FDA-approved product. Anchored to SURMOUNT-1 (tirzepatide, -20.9%) and STEP 1 (semaglutide, -14.9%).

User Experience15%

8.0/10

A price is shown before the questionnaire starts.

Trust & Safety15%

6.5/10

No pharmacy is named for its prescriptions. It shows a price before asking for health information.

Accessibility10%

5.0/10

No state list is available to check, so this is held at the midpoint rather than scored on reach.

Support10%

7.0/10

The price covers the medication, clinician visits and shipping.

6weighted dimensions
734sellers compared
Everychecked against the seller's own site
Value 25%Effectiveness 25%User Experience 15%Trust & Safety 15%Accessibility 10%Support 10%

A seller that shows no price until after the medical intake loses points on User Experience and Trust & Safety, and its review says so. How we score →

What we checked on TrimRx

Last checked October 2026
  • Checked the listed price across 4 dose or plan tiers
  • Checked what the monthly price covers, and what it leaves out
  • Checked FDA warning letters for TrimRx

Price, availability, and compliance here are read off the seller's own pages and off primary regulatory records, named in the sources below.

What signing up with TrimRx involves

What to expect on the way to a prescription: where the price appears, who fills the medication, and what the monthly price covers. It is not medical advice, and a clinician makes the prescribing decision.

  1. 1TrimRx shows a price on its own site before asking anything about you, so you can compare it with other sellers before you start a questionnaire.
  2. 2Ask TrimRx which pharmacy fills the prescription before you pay. The pharmacy's name is what lets you check its license.
  3. 3The monthly price includes the medication, clinician visits and shipping.
Price shown before you start
  • Lowest ongoing monthly price: semaglutide $299, tirzepatide $399. That leaves out membership fees, first-month rates and insurance copays.
  • Confirm that TrimRx serves your state before you start.
  • The medication is compounded, so it is not an FDA-approved product and has not been reviewed by the agency for safety, effectiveness or manufacturing quality.

Contacting TrimRx

Email
TrimRx offers email support
Hours
7 days a week, 6am to 6pm Pacific

Cancelling TrimRx

Taken from the terms TrimRx publishes. Terms change, so check the current policy before you subscribe.

Cancel any time
Yes
Minimum commitment
None on the monthly plan; multi-month plans are prepaid
Refund policy
Full refund if a provider finds you ineligible; other refund requests within 28 days of payment

Medications TrimRx lists

TrimRx lists Ozempic, Zepbound, compounded semaglutide and compounded tirzepatide. Each one has its own guide: how it works, the dosing schedule, the side effects that show up in practice, and what the trials measured.

Pricing

Prices re-verified

GLP-1 (semaglutide) monthly planCompounded
$299$199/mo
Save 33% right now
semaglutide

TrimRx's terms price the first month at $199 and each follow-up month at $299, with medication, consultation and shipping included. The home page advertises 'Starting at $179', which the terms do not tie to a month-to-month plan.

GLP-1 + GIP (tirzepatide) monthly planCompounded
$399$349/mo
Save 13% right now
tirzepatide

TrimRx's terms price the first month at $349 and each follow-up month at $399, with medication, consultation and shipping included. The home page advertises 'Starting at $279', which the terms do not tie to a month-to-month plan.

Ozempic monthly planBrand-name
$1,299/mo
semaglutide (ozempic)

Priced at $1,299 for the first month and $1,299 for follow-up months, medication included. The site footer also says TrimRx does not sell, dispense or ship branded medications, so ask how a branded prescription is filled before paying.

Zepbound monthly planBrand-name
$1,399/mo
tirzepatide (zepbound)

Priced at $1,399 for the first month and $1,399 for follow-up months, medication included. The site footer also says TrimRx does not sell, dispense or ship branded medications, so ask how a branded prescription is filled before paying.

Check the price yourself before you pay

Every figure here comes from TrimRx's own website, as of the date shown. Sellers move prices without announcing it, and promotional rates lapse, so confirm the standing cost on their site before committing.

See TrimRx pricing →

In its favor

  • Shows its price before the medical questionnaire, so you can compare it without handing over health information
  • The monthly price stays the same as your dose goes up
  • The monthly price includes the medication, clinician visits and shipping
  • We found no FDA warning letters issued to TrimRx

Against it

  • Semaglutide costs $299 a month, 50% above the $199 median for compounded semaglutide across the sellers we compare
  • Tirzepatide costs $399 a month, 48% above the $269 median for compounded tirzepatide across the sellers we compare
  • Confirm it serves your state before you start the intake
  • Ask which pharmacy fills the prescription before you pay, so you can check its license
  • Its compounded semaglutide and tirzepatide are not FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

TrimRx in brief

TrimRx offers compounded versions of two drugs, semaglutide and tirzepatide, billed monthly, with the consult, the medication and shipping folded into one fee. It is a technology platform, not a clinic or a pharmacy: affiliated physician groups decide on the prescription, and a state-licensed compounding pharmacy that TrimRx does not name prepares and ships it. The company is based in San Diego.

Its pitch is a steady price. TrimRx promises that the cost stays the same as your dose changes, and it invites people already on a GLP-1 elsewhere to switch and keep their current dose.

What you pay

TrimRx's terms set two prices for each drug, a first month and every month after:

  • Compounded semaglutide: $299 a month, with the first month at $199
  • Compounded tirzepatide: $399 a month, with the first month at $349
  • Brand Ozempic: $1,299 a month, first month included
  • Brand Zepbound: $1,399 a month, first month included

Each package covers the telehealth consult, the prescription if it is medically appropriate, the medication, shipping and ongoing medical support. TrimRx does not charge a separate membership.

Two things to watch. First, the home page advertises lower starting prices for both drugs, and the terms do not say which plan those figures belong to. Budget for the follow-up price, because that is what you pay from month two, and it puts TrimRx's semaglutide in the upper part of a market where the dearest tenth of compounded sellers charges about three times the cheapest tenth. Second, the brand-name plans come with a conflict: the terms say branded drugs are available on a limited basis and priced as above, while the site footer says TrimRx does not sell, dispense or ship branded medications and that you fill a branded prescription at your own pharmacy. Ask which applies before paying for a brand-name plan.

At refill, the compounded price does not step up with the dose, according to TrimRx's guaranteed-pricing promise. That is worth more the higher you expect to go.

Paying: cards, HSA and installments

TrimRx does not bill insurance; its pages say no insurance is needed. Its terms list Visa, Mastercard, American Express and Discover, eligible HSA and FSA cards, Apple Pay, Google Pay and PayPal, plus installment plans through Affirm, Klarna and Afterpay. No promo code is published on its own pages, though its newsletter sign-up promises subscriber discounts.

How sign-up works

The intake starts with a short quiz that asks for your height and weight, then your health history. You pay when you place the order. A clinician then reviews your answers, and state rules decide whether that review includes an online visit. If the clinician finds you are not medically eligible, TrimRx refunds the full amount.

There is a second safety net in the shipping policy: if your medication has not shipped within 14 days of the order, you can ask for a refund whatever the status of your review.

Shipping

Shipping is free and medication is sent monthly. TrimRx says compounded orders generally leave the pharmacy within 48 business hours of approval and take 3 to 5 business days to arrive, so most patients have their medication 4 to 7 business days after approval. The home page's talk of starting tomorrow is marketing; plan on about a week.

Pharmacy and clinicians

TrimRx does not name the pharmacy that compounds its drugs or the physician groups that prescribe them. It says the compounding pharmacy is state-licensed and sterile, that the products are made in FDA-registered facilities, and that the medication will not carry the TrimRx name. Compounded drugs are not FDA-approved. Ask whether the pharmacy is a 503A pharmacy or a 503B outsourcing facility, because that decides whether a state board or the FDA inspects it. The home page displays a LegitScript seal, which you can check on LegitScript's own site, and the FDA's warning signs for online medicine sellers are a quick second check on a seller that names neither its pharmacy nor its doctors.

Where it is available

TrimRx publishes no state list. Its terms say it sells only within the 50 US states and does not ship anywhere else. That is a limit on where it operates, not a promise to serve every state, so confirm your state during the intake. Our state guides list sellers by state.

Canceling and refunds

  • How: through your TrimRx account, by chat, or by phone
  • Before the prescription reaches the pharmacy: the order is canceled
  • After it reaches the pharmacy: that order ships, and the cancellation applies to later orders
  • Refund window: requests must arrive within 28 days of the payment, including refunds of unused months on a prepaid plan
  • Always refunded: a medical disqualification, a TrimRx billing error, or an order not shipped within 14 days

A 28-day window that covers unused prepaid months is worth setting against other GLP-1 sellers' cancellation and refund policies, some of which refund nothing once medication ships.

Customer service

Phone support runs seven days a week, 6 AM to 6 PM Pacific. You can also use chat, email, or the patient portal, which TrimRx says is open around the clock.

What TrimRx does not tell you

  • The name of the compounding pharmacy
  • The names of the physician groups that prescribe
  • Which states it actually serves
  • Which plan its advertised starting prices belong to
  • Whether a brand-name prescription is filled by TrimRx or left to your own pharmacy

Who it suits, and who should look elsewhere

TrimRx suits a cash payer who wants one predictable monthly fee, plans to raise the dose, and values weekend phone support and flexible payment, including HSA cards and installments. The first-month discount is real, and the follow-up price holds.

Look elsewhere if you want to know which pharmacy makes your medication before you pay, or if you need a seller that publishes its state list. Anyone set on brand-name Wegovy or Zepbound should compare other sellers with a clearer branded offer. How we score sellers sets out what each of these points is worth.

The nearest comparisons we review to TrimRx are Direct Meds ($249/month) and MangoRx ($299/month); both are worth reading before you decide.

Questions people ask about TrimRx

How much does TrimRx cost?

Compounded semaglutide is $199 for the first month and $299 a month after that. Compounded tirzepatide is $349, then $399 a month. Each fee covers the consult, the medication, shipping and ongoing support, and TrimRx says the price holds as your dose changes. The home page also shows lower starting prices that its terms do not tie to any plan, and no promo code is published on its own pages.

Does TrimRx take insurance or HSA/FSA cards?

TrimRx does not bill insurance; its pages say no insurance is needed. Its terms list eligible HSA and FSA cards among accepted payments, along with Apple Pay, Google Pay, PayPal, and installments through Affirm, Klarna or Afterpay.

Are you charged before a clinician approves you?

Yes. You pay when you place the order, and a clinician reviews your intake afterward; state rules decide whether that review includes an online visit. If the clinician finds you are not medically eligible, TrimRx issues a full refund. If your medication has not shipped within 14 days of the order, you can ask for a refund whatever the review status.

How fast does TrimRx ship?

TrimRx says compounded medication generally ships within 48 business hours of approval and arrives 3 to 5 business days after it leaves the pharmacy. From approval to your door, most patients wait about 4 to 7 business days. Shipping is free and medication is sent monthly.

Which pharmacy fills TrimRx prescriptions?

TrimRx does not name it. Its pages say compounded orders are prepared and shipped by an independent, state-licensed sterile compounding pharmacy, and that the products will not carry the TrimRx name.

Can you get brand-name Ozempic or Zepbound from TrimRx?

Its terms list an Ozempic plan at $1,299 a month and a Zepbound plan at $1,399, available on a limited basis. The site footer, though, says TrimRx does not sell, dispense or ship branded drugs and that you fill a branded prescription at your own pharmacy. Ask which applies before you pay.

How do you cancel TrimRx?

Cancel through your account, by chat or by phone. If you cancel before the prescription goes to the pharmacy, that order is canceled; after that, the order ships and the cancellation applies to later ones. Refund requests must arrive within 28 days of the payment.

How do you reach TrimRx customer service?

By phone seven days a week, 6 AM to 6 PM Pacific, by chat, by email, or through the patient portal, which TrimRx says is open around the clock.

Which states does TrimRx serve?

TrimRx publishes no state list. Its terms say it sells only within the 50 US states and ships nowhere else, so confirm your state during the intake.

The Bottom Line

TrimRx scores highest on the clinical side (which drugs it prescribes and how it doses) and lowest on price. It charges from $299 a month; its compounded tirzepatide, at $399, is 48% above the $269 median among the sellers we compare.

Score: 6.4/10Best for: compounded semaglutide at $299/month after a $199 first monthFrom: $299/mo

Before you pay TrimRx

Starting at $299 a month. Check today's price, then start the intake.

Where TrimRx is the wrong choice

No seller suits every reader, and pretending otherwise is the easiest way to sell one. On these two counts, another seller does better.

  • If the standing monthly cost is what decides it, consider WellMedRx (from $49/mo).
  • If you want a human checking in, not just a prescription, consider Found.

If none of these fits, our guide to alternatives to TrimRx sets more sellers in the same category beside TrimRx on price, states and what the price includes.

Alternatives to TrimRx

9.0/ 10
Verified partner

YourEra

Best for: semaglutide at $99/month, well below the typical price

★★★★★9.0/10

Editorial score · methodology

$99/mo
CompoundedSemaglutideTirzepatideNAD+LegitScript Verified
Get StartedRead full YourEra review →
9.1/ 10
Verified partner

Collective

Best for: flat any-dose pricing, if you can absorb a $199 annual membership on top

★★★★★9.1/10

Editorial score · methodology

$59/mo+ membership
CompoundedSemaglutideTirzepatide
Get StartedRead full Collective review →
7.3/ 10
Verified partner

Found

Best for: people who want clinician visits billed to commercial insurance, with compounded medication in the plan price

★★★★☆7.3/10

Editorial score · methodology

$149/mo+ membership
CompoundedSemaglutideTirzepatideOrforglipron
Get StartedRead full Found review →

Compare TrimRx head to head

Our head-to-head pages for TrimRx are TrimRx vs Hers, TrimRx vs Noom, TrimRx vs Gala, TrimRx vs Ivy Rx, TrimRx vs Nurx, and TrimRx vs Polly.

Frequently Asked Questions

Ask TrimRx whether it serves your state before you start the intake, and get the answer in writing.
TrimRx lists Ozempic, Zepbound, compounded semaglutide and compounded tirzepatide. It lists both FDA-approved brand-name products and cheaper compounded versions.
TrimRx lists both. Compounded semaglutide and tirzepatide come out of a licensed compounding pharmacy and cost less. The brand pens are the FDA-approved reference products and cost more. What you give up on each path is set out in the review above.
You do not need insurance to use TrimRx: it sells at cash prices. It also takes FSA and HSA cards. If you hope to use your plan, ask TrimRx whether it can bill it before you sign up.
TrimRx says the price covers medication, the clinician visit and shipping. The strip near the top of this review shows what is included and what is not.
You fill in an online intake, a licensed clinician decides whether a GLP-1 is appropriate, and if the answer is yes the medication ships to you. New patients are currently quoted $199 for the first month. TrimRx runs that whole sequence on its own site.
We found no FDA warning letters issued to TrimRx. Before you buy, weigh these: Semaglutide costs $299 a month, 50% above the $199 median for compounded semaglutide across the sellers we compare. Tirzepatide costs $399 a month, 48% above the $269 median for compounded tirzepatide across the sellers we compare. Confirm it serves your state before you start the intake. None of them rules TrimRx out, but each is worth settling before you pay.
Other sellers we cover include MangoRx, RxSpan MD, and Direct Meds. Which one fits depends on the medication, the monthly price you can sustain and whether it ships to your state, so compare those three facts before you switch.

How to check TrimRx yourself

Glossary

The words sellers use, defined. Tap any term.

Sources

Cited across this TrimRx review: primary regulatory filings, and peer-reviewed studies.

Sources & methodology — as of October 2026
  1. 1.GLP Watchdog — GLP-1 Pricing Index 2026 (our independent dataset)— GLP Watchdog.
  2. 2.FDA — Compounding and the 503A Pharmacy Framework— U.S. Food & Drug Administration.
  3. 3.FDA — Drug Shortages Database (current shortage listings)— U.S. Food & Drug Administration.
  4. 4.PCAB — Pharmacy Compounding Accreditation Board Standards— Accreditation Commission for Health Care (ACHC) / PCAB.
  5. 5.KFF — Medicaid coverage research (anti-obesity & GLP-1 drug policy)— Kaiser Family Foundation.
  6. 6.STEP 1 Trial — Once-Weekly Semaglutide in Adults with Overweight or Obesity (Wilding JPH et al.)— New England Journal of Medicine.PMID: 33567185.
  7. 7.FDA — Wegovy (semaglutide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
  8. 8.FDA — Ozempic (semaglutide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
  9. 9.SURMOUNT-1 Trial — Tirzepatide Once Weekly for the Treatment of Obesity (Jastreboff AM et al.)— New England Journal of Medicine.PMID: 35658024.
  10. 10.FDA — Zepbound (tirzepatide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
  11. 11.FDA — Mounjaro (tirzepatide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
  12. 12.SURMOUNT-5 Trial — Tirzepatide vs. Semaglutide Head-to-Head in Obesity (Aronne LJ et al.)— New England Journal of Medicine.PMID: 40353578.

See TrimRx's current pricing

Plans start at $199 a month. Whether you qualify is a clinician's decision, made after your intake.