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TrimRx Review

Semaglutide & tirzepatide GLP-1 weight-loss telehealth · Independently scored 6.3/10

Best for: compounded semaglutide at $299/month after a $199 first month

6.3
★★★☆☆3.2/5

TrimRx's strongest column is the clinical side: which molecules it will prescribe, and how it handles dosing.

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$199first month

then $299/mo ongoing

Same price at every dose

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Not stated

Coaching

Not stated

See plans →

Prices checked September 2026

Compare top-rated alternatives ↓

Three things TrimRx does not publish: the pharmacy that compounds its drugs, the states it serves, and any LegitScript certification. Specifics sit behind an intake quiz. What is visible is a cash-pay program with tiered monthly pricing plus multi-month bundles, no insurance, selling compounded semaglutide and tirzepatide shipped monthly at no shipping cost. Licensed US providers prescribe after reviewing an online medical history. The pitch is dose continuity and stable pricing: "switch and keep your current dose, no price hikes". Compounded GLP-1s are not FDA-approved.

By Ruth Calder · Enforcement Editor
Editorially reviewed (not clinically reviewed). Not medical advice · How we verify contentLast reviewed
GLP-1 from $299/moPrice shown up frontFlat across dosesIncludes medication + consultNo FDA warning letters found

Is TrimRx legit?

Yes. TrimRx is a real, operating US company, and we found no FDA warning letters issued to it. We rate it 6.3/10 overall, across six areas from price to trust and safety. Legitimate is not the same as right for you, though: that part is a decision for you and a licensed clinician.

Is there a TrimRx promo or coupon code?

TrimRx has no coupon code to enter. New patients are currently quoted $199 for the first month, then $299 a month, and the discount applies on its own. Coupon sites advertising a "TrimRx promo code" are not a source we can vouch for.

See how TrimRx compares on our rankings of the best semaglutide providers and the best tirzepatide providers.

Vetted alternatives to TrimRx

9.4/ 10
Verified partner

Trimi Health

Best for: knowing which pharmacy fills the vial: it names VialsRx

★★★★★4.7/5

Editorial score · methodology

$99/mo
CompoundedSemaglutideTirzepatide
Get StartedRead full Trimi Health review →
6.4/ 10
Verified partner

ShedRx

Best for: oral orforglipron alongside the injectables

★★★☆☆3.2/5

Editorial score · methodology

$149/mo
CompoundedSemaglutideTirzepatideOrforglipronGHK-Cu
Get StartedRead full ShedRx review →
9.0/ 10
Verified partner

bmiMD

Best for: starting below a standard dose, with microdose tiers

★★★★★4.5/5

Editorial score · methodology

$99/mo
CompoundedSemaglutideTirzepatideGlutathioneNAD+
Get StartedRead full bmiMD review →
TrimRx logo
3.2 / 5
Our editorial rating
Visit TrimRx →

from $299/mo · no insurance needed

TrimRx at a glance

Type
GLP-1 telehealth provider
Medications
Semaglutide, Tirzepatide
Starting price
$299/mo
Pricing model
Flat: the price stays the same as the dose goes up
What's included
Medication · Consult · Shipping
FDA status
No FDA warning letters found

How TrimRx scores

Six columns, each one computed from something TrimRx has published rather than from an opinion we formed: what it charges, which molecules it will dispense, what its record shows, and what the monthly figure actually buys. Where a seller keeps something back, such as its price or its pharmacy, the score reflects it. Every seller we review goes through the same six columns.

Value25%

1.6/10

$399/month is 60% above the $250 median for compounded tirzepatide across the sellers we compare.

Effectiveness25%

10.0/10

Dispenses semaglutide and tirzepatide, including the FDA-approved product. Anchored to SURMOUNT-1 (tirzepatide, -20.9%) and STEP 1 (semaglutide, -14.9%).

User Experience15%

8.0/10

A price is shown before the questionnaire starts.

Trust & Safety15%

6.5/10

No pharmacy is named for its prescriptions. It shows a price before asking for health information.

Accessibility10%

5.0/10

No state list is available to check, so this is held at the midpoint rather than scored on reach.

Support10%

7.0/10

The price covers the medication, clinician visits and shipping.

6weighted dimensions
588sellers compared
Everychecked against the seller's own site
Value 25%Effectiveness 25%User Experience 15%Trust & Safety 15%Accessibility 10%Support 10%

A seller that shows no price until after the medical intake loses points on User Experience and Trust & Safety, and its review says so. How we score →

What we checked on TrimRx

Last checked September 2026
  • Checked the listed price across 4 dose or plan tiers
  • Checked what the monthly price covers, and what it leaves out
  • Checked FDA warning letters for TrimRx

Price, availability, and compliance here are read off the seller's own pages and off primary regulatory records, named in the sources below.

What signing up with TrimRx involves

What to expect on the way to a prescription: where the price appears, who fills the medication, and what the monthly price covers. It is not medical advice, and a clinician makes the prescribing decision.

  1. 1TrimRx shows a price on its own site before asking anything about you, so you can compare it with other sellers before you start a questionnaire.
  2. 2Ask TrimRx which pharmacy fills the prescription before you pay. The pharmacy's name is what lets you check its license.
  3. 3The monthly price includes the medication, clinician visits and shipping.
Price shown before you start
  • Lowest ongoing monthly price: semaglutide $299, tirzepatide $399. That leaves out membership fees, first-month rates and insurance copays.
  • Confirm that TrimRx serves your state before you start.
  • The medication is compounded, so it is not an FDA-approved product and has not been reviewed by the agency for safety, effectiveness or manufacturing quality.

Contacting TrimRx

Email
TrimRx offers email support
Hours
7 days a week, 6am to 6pm Pacific

Cancelling TrimRx

Taken from the terms TrimRx publishes. Terms change, so check the current policy before you subscribe.

Cancel any time
Yes
Minimum commitment
None on the monthly plan; multi-month plans are prepaid
Refund policy
Full refund if a provider finds you ineligible; other refund requests within 28 days of payment

GLP-1 medications TrimRx offers

Each one has its own guide: how the molecule works, the dosing schedule, the side effects that show up in practice, and what the trials actually measured.

Pricing

Prices re-verified

GLP-1 (semaglutide) monthly planCompounded
$299$199/mo
Save 33% right now
semaglutide

TrimRx's terms price the first month at $199 and each follow-up month at $299, with medication, consultation and shipping included. The home page advertises 'Starting at $179', which the terms do not tie to a month-to-month plan.

GLP-1 + GIP (tirzepatide) monthly planCompounded
$399$349/mo
Save 13% right now
tirzepatide

TrimRx's terms price the first month at $349 and each follow-up month at $399, with medication, consultation and shipping included. The home page advertises 'Starting at $259', which the terms do not tie to a month-to-month plan.

Ozempic monthly planBrand-name
$1299/mo
semaglutide (ozempic)

Priced at $1,299 for the first month and $1,299 for follow-up months, medication included.

Zepbound monthly planBrand-name
$1399/mo
tirzepatide (zepbound)

Priced at $1,399 for the first month and $1,399 for follow-up months, medication included.

Check the price yourself before you pay

Every figure here was read off TrimRx's own checkout on the date shown. Sellers move prices without announcing it, and promotional rates lapse, so confirm the standing cost on their site before committing.

See TrimRx pricing →

In its favor

  • Shows its price before the medical questionnaire, so you can compare it without handing over health information
  • The monthly price stays the same as your dose goes up
  • The monthly price includes the medication, clinician visits and shipping
  • We found no FDA warning letters issued to TrimRx

Against it

  • Semaglutide costs $299 a month, 62% above the $185 median for compounded semaglutide across the sellers we compare
  • Tirzepatide costs $399 a month, 60% above the $250 median for compounded tirzepatide across the sellers we compare
  • Confirm it serves your state before you start the intake
  • Ask which pharmacy fills the prescription before you pay, so you can check its license
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

What TrimRx charges

Two numbers matter here and only one of them is the price. $199 is the opening month; $299/month is what TrimRx charges after that.

  • Compounded semaglutide: $199 first month, then $299/month
  • Compounded tirzepatide: $349 first month, then $399/month
  • Brand-name semaglutide (ozempic): $1,299/month
  • Brand-name tirzepatide (zepbound): $1,399/month

For compounded tirzepatide, the median across the sellers we compare is $250/month, so TrimRx's $399 is a premium, and a premium has to buy something. Discounting the first month does not change the twelve-month total by much.

Direct Meds dispenses semaglutide and tirzepatide from $249/month, which makes it the fair comparison to run before you commit here.

What TrimRx dispenses

TrimRx prescribes semaglutide (approved as Wegovy and Ozempic) and tirzepatide (approved as Zepbound and Mounjaro). Between them these are the pair carrying the strongest published outcome data. Both routes are available: the FDA-approved pen, or a compounded version at lower cost. The difference is not cosmetic. The approved product has been reviewed for safety, efficacy and manufacturing quality, and a compounded preparation has not.

Safety and disclosure

TrimRx tells you its price before you start the medical questionnaire. We found no FDA warning letters issued to TrimRx. Because the medication is compounded, the most useful question to ask at intake is which licensed pharmacy fills the prescription. If TrimRx will not tell you, treat that as a warning sign. How we weigh oversight, disclosure and price is set out in our scoring methodology.

Who should look elsewhere

  • You care most about the twelve-month total, not the first bill. A flat-rate seller such as Collective will usually win that math.
  • You would be choosing on the advertised figure. The introductory month is real, but it is not what you will pay in month three.
  • You need insurance to cover the cost. Check whether TrimRx bills your plan before you start.

It fits if

  • you want the price to stop moving as your dose climbs
  • you want a cheap way to find out whether the medication suits you before committing

Our read

TrimRx is a cheap way to start and an ordinary way to continue. Use the $199 month for what it is good for, finding out whether the medication works for you, and re-run the numbers against $299/month before you let it renew twice. MangoRx is the nearest comparison we review, and worth reading alongside this.

The Bottom Line

TrimRx's strongest column is the clinical side: which molecules it will prescribe, and how it handles dosing.

Score: 6.3/10Best for: compounded semaglutide at $299/month after a $199 first monthFrom: $199/mo

Before you pay TrimRx

Starting at $199 a month. Check today's price, then start the intake.

Where TrimRx is the wrong choice

No seller suits every reader, and pretending otherwise is the easiest way to sell one. On these two counts, another seller does better.

  • If the standing monthly cost is what decides it, consider Sesame Care (from $59/mo).
  • If you want a human checking in, not just a prescription, consider ShedRx.

Compare TrimRx head to head

The sellers closest to TrimRx on medication and price.

Frequently Asked Questions

Three things TrimRx does not publish: the pharmacy that compounds its drugs, the states it serves, and any LegitScript certification. Specifics sit behind an intake quiz. What is visible is a cash-pay program with tiered monthly pricing plus multi-month bundles, no insurance, selling compounded semaglutide and tirzepatide shipped monthly at no shipping cost. Licensed US providers prescribe after reviewing an online medical history. The pitch is dose continuity and stable pricing: "switch and keep your current dose, no price hikes". Compounded GLP-1s are not FDA-approved. We rate it 6.3/10 overall.
The standing rate at TrimRx is $299 a month. The $199 figure is a first month, not what you pay from month two. Cost also moves with the medication and the dose, so read the row in the pricing table above that matches yours.
Ask TrimRx whether it serves your state before you start the intake, and get the answer in writing.
TrimRx sells semaglutide (sold as Wegovy and Ozempic) and tirzepatide (sold as Zepbound and Mounjaro). Both are listed in FDA-approved brand form and in a cheaper compounded form.
TrimRx lists both. Compounded semaglutide and tirzepatide come out of a licensed compounding pharmacy and cost less. The brand pens are the FDA-approved reference products and cost more. What you give up on each path is set out in the review above.
You do not need insurance to use TrimRx: it sells at cash prices. If you hope to use your plan, ask TrimRx whether it can bill it before you sign up.
TrimRx says the price covers medication, the clinician visit and shipping. The strip near the top of this review shows what is included and what is not.
You fill in an online intake, a licensed clinician decides whether a GLP-1 is appropriate, and if the answer is yes the medication ships to you. New patients are currently quoted $199 for the first month. TrimRx runs that whole sequence on its own site.
We found no FDA warning letters issued to TrimRx. Before you buy, weigh these: Semaglutide costs $299 a month, 62% above the $185 median for compounded semaglutide across the sellers we compare. Tirzepatide costs $399 a month, 60% above the $250 median for compounded tirzepatide across the sellers we compare. Confirm it serves your state before you start the intake. None of them rules TrimRx out, but each is worth settling before you pay.

Glossary

The words sellers use, defined. Tap any term.

Sources

Cited across this TrimRx review: primary regulatory filings, and peer-reviewed studies.

Sources & methodology — as of September 2026
  1. 1.GLP Watchdog — GLP-1 Pricing Index 2026 (our independent dataset)— GLP Watchdog.
  2. 2.FDA — Compounding and the 503A Pharmacy Framework— U.S. Food & Drug Administration.
  3. 3.FDA — Drug Shortages Database (current shortage listings)— U.S. Food & Drug Administration.
  4. 4.PCAB — Pharmacy Compounding Accreditation Board Standards— Accreditation Commission for Health Care (ACHC) / PCAB.
  5. 5.KFF — Medicaid coverage research (anti-obesity & GLP-1 drug policy)— Kaiser Family Foundation.
  6. 6.STEP 1 Trial — Once-Weekly Semaglutide in Adults with Overweight or Obesity (Wilding JPH et al.)— New England Journal of Medicine.PMID: 33567185.
  7. 7.FDA — Wegovy (semaglutide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
  8. 8.FDA — Ozempic (semaglutide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
  9. 9.SURMOUNT-1 Trial — Tirzepatide Once Weekly for the Treatment of Obesity (Jastreboff AM et al.)— New England Journal of Medicine.PMID: 35658024.
  10. 10.FDA — Zepbound (tirzepatide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
  11. 11.FDA — Mounjaro (tirzepatide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
  12. 12.SURMOUNT-5 Trial — Tirzepatide vs. Semaglutide Head-to-Head in Obesity (Garvey WT et al.)— New England Journal of Medicine.PMID: 40334173.

See TrimRx's current pricing

Plans start at $199 a month. Whether you qualify is a clinician's decision, made after your intake.