GLP Watchdog

Polly vs TrimRx

Neither Polly nor TrimRx has an FDA warning letter on record. On compounded semaglutide injection, Polly costs $1,440 less a year at standing rates: $179 a month against $299 a month at TrimRx. It is one of two products the two sell at comparable terms.

To see where both sit among the other sellers, read our best weight-loss injection providers board.

By Ruth Calder · Enforcement Editor
Editorially reviewed. Not medical advice · How we verify contentLast reviewed

The record

Polly / TrimRx

Polly logo

Polly

8.4/10

Featured pick (affiliate partner)

TrimRx logo

TrimRx

6.4/10

FDA warning letters
None on record
None on record
Pharmacy
None named in our record
Lowest standing price
$179/moCompounded semaglutide injection
$299/moCompounded semaglutide injection
States
All 50 states
No state list published
Checked
Prices captured Record checked November 2026
Prices captured Record checked October 2026
Visit Polly
Visit TrimRx

TrimRx is our featured pick on this page because it is an affiliate partner: we are paid if you sign up through our link. Polly pays us nothing. The scores are computed the same way for both and are shown as computed (Polly 8.4, TrimRx 6.4). How we are paid

What the record shows

  1. 01

    Neither Polly nor TrimRx has an FDA warning letter on record.

  2. 02

    Polly names two pharmacies, all 503A. TrimRx names no compounding pharmacy in our record.

  3. 03

    On compounded semaglutide injection, Polly costs $1,440 less a year at standing rates: $179 a month against $299 a month at TrimRx. It is one of two products the two sell at comparable terms.

  4. 04

    Only TrimRx lists a price for brand-name semaglutide pen and brand-name tirzepatide pen.

  5. 05

    Polly lists all 50 states. TrimRx publishes no state list.

  6. 06

    Polly does not state its cancellation terms; TrimRx states you can cancel at any time.

Prices and terms, product by product

A price is set against the other side only for the same product, and only when both are standing monthly or 4-week rates. Those pairs are compared by yearly cost.

Polly

TrimRx

Compounded semaglutide injection

$179/moLower

$2,148 a year

$299/mo

$3,588 a year

Compounded tirzepatide injection

$279/moLower

$3,348 a year

$399/mo

$4,788 a year

Brand-name semaglutide pen
Not sold or not priced

$1,299/mo

$15,588 a year

Brand-name tirzepatide pen
Not sold or not priced

$1,399/mo

$16,788 a year

Price includes
Medication, clinician visits, shipping
Medication, clinician visits, shipping
Cancel any time
Not stated
Yes, stated
Minimum term
Month to month, or a 3- or 6-month supply charged at checkout
None on the monthly plan; multi-month plans are prepaid
Refunds
Full refund only before the medical intake is submitted; 3- and 6-month plans cannot be refunded once the first month has passed
Full refund if a provider finds you ineligible; other refund requests within 28 days of payment
Early-exit fee
Yes
Not stated

Read off each seller’s own pages. Polly: October 17, 2026. TrimRx: October 25, 2026. Every plan and dose we hold is on the full review.

The case for each

The case for Polly

8.4/10
  • $1,440 a year less on compounded semaglutide injection
  • $1,440 a year less on compounded tirzepatide injection
  • Names its compounding pharmacy
Visit Polly

The case for TrimRx

6.4/10
Featured pick (affiliate partner)
  • Sells brand-name semaglutide pen and brand-name tirzepatide pen, which Polly does not price
  • States you can cancel at any time
  • Names no compounding pharmacy
  • Publishes no state list
Visit TrimRx

Scores

Polly 8.4 · TrimRx 6.4 out of 10. Six weighted parts.

Value25%

5.8A
vs
B
2.2

Effectiveness25%

10.0A
vs
B
10.0

User Experience15%

8.0A
vs
B
8.0

Trust & Safety15%

10.0A
vs
B
6.5

Accessibility10%

10.0A
vs
B
5.0

Support10%

7.0A
vs
B
7.0

The score is the same formula for every seller. Payment does not enter it. Method

Polly vs TrimRx: questions

Neither Polly nor TrimRx has an FDA warning letter on record. Letters are matched to a seller by company, domain and address, never by a similar name.
Polly names two pharmacies, all 503A. TrimRx names no compounding pharmacy in our record. A 503A pharmacy compounds for named patients on a prescription; a 503B outsourcing facility is registered with FDA and inspected under federal manufacturing rules.
Polly, by $1,440 a year at standing rates. Polly: $179 a month, about $2,148 a year. TrimRx: $299 a month, about $3,588 a year.
Polly does not state its cancellation terms. TrimRx states you can cancel at any time; refunds: full refund if a provider finds you ineligible; other refund requests within 28 days of payment.
TrimRx is our featured pick on this page because it is an affiliate partner: we are paid if you sign up through our link. Polly pays us nothing. The scores are computed the same way for both and are shown as computed (Polly 8.4, TrimRx 6.4).

Other sellers we are paid by

Affiliate partners outside this pair. Each has its own record and review, scored the same way.

Sellers closest to these two

Matched on molecule, form and price. Every pair we list · The register

Brand names on this page are registered marks. Novo Nordisk holds Wegovy®, Ozempic® and Rybelsus®; Eli Lilly holds Zepbound®, Mounjaro® and Foundayo®. Neither company has any tie to GLP Watchdog. Trademarks