SkyRx Review

Semaglutide GLP-1 weight-loss telehealth · Independently scored 6.7/10

Best for: compounded semaglutide at $199/month

6.7
★★★☆☆3.4/5

SkyRx's strongest column is the clinical side — which molecules it will prescribe, and how it handles dosing.

$199/mo
Same price at every dose

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Not stated

Coaching

Not stated

See plans →

No insurance neededVetted by our editors

Compare top-rated alternatives ↓

Pay 12 months upfront and the rate is 199 dollars per month, one figure taking in shipping, the doctor visit, supplies and the drug, with insurance beside the point. Compounded semaglutide comes as oral drops or an injection; compounded tirzepatide is marked coming soon. 503B compounding pharmacies registered with the FDA do the dispensing. Coverage does not yet extend to all 50 states for GLP-1s. Draper, Utah is home to sky-rx.co, and support answers at 855-759-7979 or by email.

By Ruth Calder · Enforcement Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
GLP-1 from $199/moPrice shown up frontFlat across dosesIncludes medication + consultNo FDA letter on record

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Best for: semaglutide at $119/month, 37% under the register median

★★★★4/5

Editorial score · methodology

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Best for: tirzepatide at $169/month, 37% under the register median

★★★★4.4/5

Editorial score · methodology

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SkyRx
3.4 / 5
Our editorial rating
Visit SkyRx

from $199/mo · no insurance needed

SkyRx at a glance

Type
GLP-1 telehealth provider
Medications
Semaglutide
Starting price
$199/mo (199/mo on a 12-month prepaid subscription; includes med, supplies, visit, shipping)
Pricing model
Flat — dose increases don't raise the monthly price
What's included
Medication · Consult · Shipping
FDA status
No FDA warning letter on record

How SkyRx scores

Six columns, each one computed from something SkyRx has published rather than from an opinion we formed: what it charges, which molecules it will dispense, what its record shows, and what the monthly figure actually buys. Where it publishes nothing, that absence is what gets scored. Every seller in the register goes through the same six columns.

Value25%

4.6/10

$199/month is 5% above the register median of $189 for compounded semaglutide.

Effectiveness25%

8.5/10

Dispenses semaglutide, compounded only. Anchored to SURMOUNT-1 (tirzepatide, -20.9%) and STEP 1 (semaglutide, -14.9%).

User Experience15%

8.0/10

On the seller's own pages, a price is published before the questionnaire starts.

Trust & Safety15%

6.5/10

does not name a dispensing pharmacy; shows a price before asking for health information. Our verification confidence is medium.

Accessibility10%

5.0/10

Publishes no list of states served, so coverage cannot be confirmed either way. Capped at the midpoint — this measures disclosure, not reach.

Support10%

7.0/10

The price covers medication, consult, shipping.

6weighted dimensions
560sellers in the register
Everychecked against the seller's own site
Value 25%Effectiveness 25%User Experience 15%Trust & Safety 15%Accessibility 10%Support 10%

A seller that will not show a price before an intake loses points on Value and carries that note in its review. Withholding the number is itself a finding. How we score →

What we checked on SkyRx

Last checked August 2026
  • Re-read the price on file across 1 dose or plan tier
  • Established what the monthly figure covers, and what it leaves out
  • Searched our FDA enforcement register for this operator

Price, availability, and compliance here are read off the seller's own pages and off primary regulatory records, named in the sources below. Editorial confidence in this data: medium.

What signing up with SkyRx involves

Assembled from this seller’s entry in the register — the price record, the state list, the dispensing pharmacy where one is named, and what the monthly figure covers. It describes what a reader can expect to meet on the way to a prescription, and what is missing from the seller’s own disclosures. It is not a clinical judgment and not a prescribing decision.

  1. 1SkyRx publishes a price on its own site before asking anything about you. You can compare it against this register without starting a questionnaire.
  2. 2The intake is a written questionnaire. No live video visit or baseline bloodwork is recorded as required.
  3. 3SkyRx does not say which pharmacy dispenses the medication. That is common here and it means you cannot check the pharmacy's record before you buy.
  4. 4The monthly price is recorded as covering medication, consult, shipping.
Price shown before you start
  • Cheapest standing monthly prices on record: semaglutide $199. Membership fees, first-month rates and insured copays are excluded from those figures.
  • No state list is published, so whether SkyRx serves your state cannot be confirmed from its site.
  • The medication is compounded, so it is not an FDA-approved product and has not been reviewed by the agency for safety, effectiveness or manufacturing quality.

SkyRx support, as documented

GLP-1 medications SkyRx offers

Each one has its own guide: how the molecule works, the dosing schedule, the side effects that show up in practice, and what the trials actually measured.

Pricing

Prices re-verified

All doses (flat)Compounded
$199/mo
semaglutide

199/mo on a 12-month prepaid subscription; includes med, supplies, visit, shipping

Check the price yourself before you pay

Every figure here was read off SkyRx's own checkout on the date shown. Sellers move prices without announcing it, and promotional rates lapse, so confirm the standing cost on their site before committing.

See SkyRx pricing →

In its favor

  • Semaglutide at $199 a month, within the normal band around this register's $189 median for the same drug and form
  • Publishes a price on its own site before the medical questionnaire, so it can be compared without handing over health information
  • The monthly price is recorded as flat across doses, so it does not climb as the dose is titrated up
  • The monthly figure covers medication, consult, shipping
  • No FDA warning letter matched this operator when we searched our enforcement register

Against it

  • No state list is on record here, so whether it serves your state cannot be confirmed from this page
  • No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
  • Its semaglutide is compounded rather than FDA-approved, so it has not been reviewed by the agency for safety, effectiveness or manufacturing quality

What SkyRx charges

The standing price at SkyRx is $199/month, unchanged as the dose goes up. That sits above the middle of the market, which puts the burden on whatever else is in the package. Flat dose pricing matters more than it reads: on a tiered plan the bill grows as the dose does, which means the figure that persuaded you to sign up is not the figure you end up living with.

  • Compounded semaglutide — $199/month

The median standing price across the GLP-1 providers we track is about $169/month, so this is a premium, and a premium has to buy something. Check what is bundled before accepting it.

Found dispenses semaglutide from $149/month, which makes it the honest comparison to run before committing here.

What SkyRx dispenses

SkyRx prescribes semaglutide (approved as Wegovy and Ozempic). Between them these are one of the most heavily studied molecules in this class. What arrives is compounded at a licensed pharmacy, not an approved pen. That is the reason it costs less, and the reason the finished preparation carries no FDA review behind it.

A needle-free oral option is genuinely uncommon and is the reason some readers will look at SkyRx at all. Set expectations on the evidence, though: the published weight-loss trials for these molecules used injections. Oral and sublingual delivery of peptides is far less studied, so treat it as a route that solves the needle problem rather than as a demonstrated equal to the shot.

What we could verify

On the record: it dispenses through an accredited compounding pharmacy. We searched the federal warning-letter record for this operator and came back with nothing. Because the medication is compounded and no dispensing pharmacy is named publicly, the single most useful question to ask at intake is which licensed pharmacy fills the prescription. A seller that will not answer that has told you something. How we weigh oversight, disclosure and price evidence is set out in our scoring methodology.

Who should look elsewhere

  • You are optimizing for the twelve-month total rather than the first bill — a flat-rate seller such as CoreAge Rx will usually win that arithmetic.
  • You want the FDA-approved pen specifically. Nothing here is the approved finished product.
  • You need to bill insurance. Like most of this market, this is cash-pay.

It fits if

  • you want the price to stop moving as your dose climbs
  • injections are the thing keeping you from starting

Our read

SkyRx costs more than the middle of this market, and the oral option is the clearest thing that premium buys. If the extras it charges for are ones you would actually use, that is a defensible trade. If not, the same molecule is available for less. Breeze Meds is the nearest comparison we track, and worth reading alongside this.

The Bottom Line

SkyRx's strongest column is the clinical side — which molecules it will prescribe, and how it handles dosing.

Score: 6.7/10Best for: compounded semaglutide at $199/monthFrom: $199/mo

Before you pay SkyRx

Starting at $199/month. Check today's price, then book the free consultation.

Where SkyRx is the wrong choice

No seller in this register suits every reader, and saying otherwise would be the easiest way to sell one. On these four counts another entry does better.

  • If you need the FDA-approved pen rather than a compounded vial, consider Found.
  • If the standing monthly cost is what decides it, consider Telos Rx (from $99/mo).
  • If you want a human checking in, not just a prescription, consider Oak.

Frequently Asked Questions

Glossary

The words sellers use, defined. Tap any term.

Sources

Cited across this SkyRx review: primary regulatory filings, and peer-reviewed studies.

Sources & methodology — as of August 2026
  1. 1.GLP Watchdog — GLP-1 Pricing Index 2026 (our independent dataset)GLP Watchdog.
  2. 2.FDA — Compounding and the 503A Pharmacy FrameworkU.S. Food & Drug Administration.
  3. 3.FDA — Drug Shortages Database (current shortage listings)U.S. Food & Drug Administration.
  4. 4.PCAB — Pharmacy Compounding Accreditation Board StandardsAccreditation Commission for Health Care (ACHC) / PCAB.
  5. 5.KFF — Medicaid coverage research (anti-obesity & GLP-1 drug policy)Kaiser Family Foundation.
  6. 6.STEP 1 Trial — Once-Weekly Semaglutide in Adults with Overweight or Obesity (Wilding JPH et al.)New England Journal of Medicine.PMID: 33567185.
  7. 7.FDA — Wegovy (semaglutide) Approval History via Drugs@FDAU.S. Food & Drug Administration.
  8. 8.FDA — Ozempic (semaglutide) Prescribing Information via Drugs@FDAU.S. Food & Drug Administration.

See SkyRx's current pricing

Plans start at $199/month. The free consultation is where you learn whether you qualify, and what it costs today.