Sipra Review
Semaglutide & tirzepatide GLP-1 weight-loss telehealth · Independently scored 7.6/10
Best for: people ready to prepay three months or more for compounded semaglutide or tirzepatide
Sipra's strongest column is the clinical side: which molecules it will prescribe, and how it handles dosing.
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charged as a multi-month plan up front
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
Prices checked October 2026
Sipra is a Wyoming-registered telehealth platform whose prescribing runs through the MD Integrations physician network. It sells compounded semaglutide and tirzepatide as B12-blended weekly injections, dissolving tablets and microdose plans. Plans start at three months, paid upfront: semaglutide injections are $189 a month ($567) and tirzepatide $249 ($747), falling to $149 and $199 on a 12-month plan. You are charged only after a physician approves.
Is Sipra legit?
Yes. Sipra is a real, operating US company, and we found no FDA warning letters issued to it. We rate it 7.6/10 overall, across six areas from price to trust and safety. Legitimate is not the same as right for you, though: that part is a decision for you and a licensed clinician.
Is there a Sipra promo or coupon code?
We know of no promo or coupon code for Sipra. Its listed price is $149 a month. Coupon sites advertising "Sipra discount codes" are not a source we can vouch for, and any genuine offer shows at checkout without a code.
See how Sipra compares on our rankings of the best semaglutide providers and the best tirzepatide providers.
Vetted alternatives to Sipra
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Trimi Health
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Sipra at a glance
- Type
- GLP-1 telehealth provider
- Medications
- Semaglutide, Tirzepatide
- Starting price
- $149/mo
- Pricing model
- Flat: the price stays the same as the dose goes up
- What's included
- Medication · Consult · Shipping
- FDA status
- No FDA warning letters found
How Sipra scores
Six columns, each one computed from something Sipra has published rather than from an opinion we formed: what it charges, which molecules it will dispense, what its record shows, and what the monthly figure actually buys. Where a seller keeps something back, such as its price or its pharmacy, the score reflects it. Every seller we review goes through the same six columns.
Value25%
6.7/10$149/month is 21% below the $188 median for compounded semaglutide across the sellers we compare. That figure is a multi-month plan paid up front, not a month-to-month rate, so the comparison flatters it.
Effectiveness25%
10.0/10Dispenses semaglutide and tirzepatide, compounded only. Anchored to SURMOUNT-1 (tirzepatide, -20.9%) and STEP 1 (semaglutide, -14.9%).
User Experience15%
8.0/10A price is shown before the questionnaire starts.
Trust & Safety15%
6.5/10No pharmacy is named for its prescriptions. It shows a price before asking for health information.
Accessibility10%
5.0/10No state list is available to check, so this is held at the midpoint rather than scored on reach.
Support10%
7.0/10The price covers the medication, clinician visits and shipping.
A seller that shows no price until after the medical intake loses points on User Experience and Trust & Safety, and its review says so. How we score →
What we checked on Sipra
Last checked October 2026- Checked the listed price across 6 dose or plan tiers
- Checked what the monthly price covers, and what it leaves out
- Checked FDA warning letters for Sipra
Price, availability, and compliance here are read off the seller's own pages and off primary regulatory records, named in the sources below.
What signing up with Sipra involves
What to expect on the way to a prescription: where the price appears, who fills the medication, and what the monthly price covers. It is not medical advice, and a clinician makes the prescribing decision.
- 1Sipra shows a price on its own site before asking anything about you, so you can compare it with other sellers before you start a questionnaire.
- 2Ask Sipra which pharmacy fills the prescription before you pay. The pharmacy's name is what lets you check its license.
- 3The monthly price includes the medication, clinician visits and shipping.
- Lowest ongoing monthly price: semaglutide $149, tirzepatide $199. That leaves out membership fees, first-month rates and insurance copays.
- Confirm that Sipra serves your state before you start.
- The medication is compounded, so it is not an FDA-approved product and has not been reviewed by the agency for safety, effectiveness or manufacturing quality.
Contacting Sipra
- Sipra offers email support
Cancelling Sipra
Taken from the terms Sipra publishes. Terms change, so check the current policy before you subscribe.
- Cancel any time
- Yes
- Minimum commitment
- Shortest published plan is 3 months, paid up front; 6- and 12-month plans also offered. Plans recur until paused or canceled.
- Refund policy
- "Canceling on its own does not refund money already charged." On 6- and 12-month plans, unstarted quarters are refunded under the Sipra Promise.
- Early-termination fee
- None
GLP-1 medications Sipra offers
Each one has its own guide: how the molecule works, the dosing schedule, the side effects that show up in practice, and what the trials actually measured.
Pricing
Prices re-verified
$189 a month on the shortest plan published, billed as one $567 payment. The same table lists $169 a month on a 6-month plan ($1,014) and $149 on a 12-month plan ($1,788). No 1-month price is published.
$249 a month on the 3-month plan, one $747 payment. $219 a month on 6 months ($1,314) and $199 on 12 months ($2,388).
Low-dose semaglutide plan: $149 a month for 3 months, $129 for 6 and $119 for 12.
Low-dose tirzepatide plan: $199 a month for 3 months, $179 for 6 and $159 for 12.
Sold as SemaMelt. $249 a month for 3 months, $219 for 6 and $199 for 12.
Sold as TirzaMelt. $269 a month for 3 months, $249 for 6 and $239 for 12.
Check the price yourself before you pay
Every figure here was read off Sipra's own checkout on the date shown. Sellers move prices without announcing it, and promotional rates lapse, so confirm the standing cost on their site before committing.
In its favor
- Semaglutide costs $149 a month, 21% below the $188 median for compounded semaglutide across the sellers we compare
- Tirzepatide costs $199 a month, 20% below the $250 median for compounded tirzepatide across the sellers we compare
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- The monthly price stays the same as your dose goes up
- The monthly price includes the medication, clinician visits and shipping
- We found no FDA warning letters issued to Sipra
Against it
- Confirm it serves your state before you start the intake
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
What Sipra charges
Sipra charges $149/month, and holds that rate across every dose. That sits at the affordable end of what we see. Flat dose pricing matters more than it sounds: on a tiered plan the bill grows with the dose, so the figure that got you to sign up is not the one you end up paying.
- Compounded semaglutide: $189/month
- Compounded tirzepatide: $249/month
- Compounded semaglutide: $149/month
- Compounded tirzepatide: $199/month
- Compounded semaglutide: $249/month
- Compounded tirzepatide: $269/month
For compounded semaglutide, the median across the sellers we compare is $188/month, so Sipra's $149 is genuinely below the middle, not just advertised that way.
Found, at about $149/month, is the closest like-for-like alternative we review.
What Sipra dispenses
Sipra prescribes semaglutide (approved as Wegovy and Ozempic) and tirzepatide (approved as Zepbound and Mounjaro). Between them these are the two best-evidenced weight-loss molecules currently on the market. These are compounded preparations from a licensed pharmacy rather than approved pens, which is where the lower price comes from. A compounded drug is not FDA-approved as a finished product: the specific preparation has not been reviewed for safety, efficacy or manufacturing quality.
A needle-free oral option is genuinely uncommon and is the reason some readers will look at Sipra at all. Set expectations on the evidence, though: the published weight-loss trials for these molecules used injections. Oral and sublingual delivery of peptides is far less studied, so treat it as a route that solves the needle problem rather than as a proven equal to the shot.
Safety and disclosure
Sipra tells you its price before you start the medical questionnaire. We found no FDA warning letters issued to Sipra. Because the medication is compounded, the most useful question to ask at intake is which licensed pharmacy fills the prescription. If Sipra will not tell you, treat that as a warning sign. How we weigh oversight, disclosure and price is set out in our scoring methodology.
Who should look elsewhere
- You want the FDA-approved pen specifically. Everything listed here is compounded.
- You need insurance to cover the cost. Check whether Sipra bills your plan before you start.
It fits if
- the lowest standing monthly cost is what you are solving for
- you want the price to stop moving as your dose climbs
- injections are the thing keeping you from starting
Our read
Sipra competes on price without an obvious sacrifice elsewhere: $149/month, no FDA warning letters.
The Bottom Line
Sipra's strongest column is the clinical side: which molecules it will prescribe, and how it handles dosing.
Before you pay Sipra
Starting at $149 a month. Check today's price, then start the intake.
Where Sipra is the wrong choice
No seller suits every reader, and pretending otherwise is the easiest way to sell one. On these three counts, another seller does better.
- If you need the FDA-approved pen rather than a compounded vial, consider Sesame Care.
- If the standing monthly cost is what decides it, consider Collective (from $59/mo).
- If you want a human checking in, not just a prescription, consider ShedRx.
Compare Sipra head to head
The sellers closest to Sipra on medication and price.
Frequently Asked Questions
Glossary
The words sellers use, defined. Tap any term.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Sources
Cited across this Sipra review: primary regulatory filings, and peer-reviewed studies.
Sources & methodology — as of October 2026
- 1.GLP Watchdog — GLP-1 Pricing Index 2026 (our independent dataset)— GLP Watchdog.
- 2.FDA — Compounding and the 503A Pharmacy Framework— U.S. Food & Drug Administration.
- 3.FDA — Drug Shortages Database (current shortage listings)— U.S. Food & Drug Administration.
- 4.PCAB — Pharmacy Compounding Accreditation Board Standards— Accreditation Commission for Health Care (ACHC) / PCAB.
- 5.KFF — Medicaid coverage research (anti-obesity & GLP-1 drug policy)— Kaiser Family Foundation.
- 6.STEP 1 Trial — Once-Weekly Semaglutide in Adults with Overweight or Obesity (Wilding JPH et al.)— New England Journal of Medicine.PMID: 33567185.
- 7.FDA — Wegovy (semaglutide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
- 8.FDA — Ozempic (semaglutide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
- 9.SURMOUNT-1 Trial — Tirzepatide Once Weekly for the Treatment of Obesity (Jastreboff AM et al.)— New England Journal of Medicine.PMID: 35658024.
- 10.FDA — Zepbound (tirzepatide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
- 11.FDA — Mounjaro (tirzepatide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
- 12.SURMOUNT-5 Trial — Tirzepatide vs. Semaglutide Head-to-Head in Obesity (Garvey WT et al.)— New England Journal of Medicine.PMID: 40334173.
See Sipra's current pricing
Plans start at $149 a month. Whether you qualify is a clinician's decision, made after your intake.