altRX vs Sipra
altRX and Sipra both sell semaglutide and tirzepatide; this is how their prices, coverage and records differ.
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Sipra
Best for: people ready to prepay three months or more for compounded semaglutide or tirzepatide
Visit Sipra →If you are choosing between altRX and Sipra, price alone will not settle it. Both prescribe semaglutide and tirzepatide, so moving from one to the other would not change your drug. They tie at 7.6 on our six-part score. One of the two has an FDA warning letter on record, covered below.
altRX vs Sipra price
altRX and Sipra start at the same figure, $149 a month, so the entry price does not separate them. Look at what each price covers and at the per-drug prices below.
Drug by drug: Semaglutide costs the same at both, $149 a month; tirzepatide is cheaper at Sipra ($199 a month on a prepaid plan vs $249 a month).
Medications and formats
Both sell semaglutide and tirzepatide.
On format, altRX prices compounded injections and brand-name pens, while Sipra prices compounded injections.
If you want the FDA-approved brand rather than a compounded version, altRX is the only one of the two with a brand-name price.
Where each one treats patients
altRX lists 50 states, and Sipra does not publish where it ships.
Pricing
altRX
Sipra
$189 a month on the shortest plan published, billed as one $567 payment. The same table lists $169 a month on a 6-month plan ($1,014) and $149 on a 12-month plan ($1,788). No 1-month price is published.
$249 a month on the 3-month plan, one $747 payment. $219 a month on 6 months ($1,314) and $199 on 12 months ($2,388).
Low-dose semaglutide plan: $149 a month for 3 months, $129 for 6 and $119 for 12.
Low-dose tirzepatide plan: $199 a month for 3 months, $179 for 6 and $159 for 12.
Sold as SemaMelt. $249 a month for 3 months, $219 for 6 and $199 for 12.
Sold as TirzaMelt. $269 a month for 3 months, $249 for 6 and $239 for 12.
What each price covers
Both prices cover the clinician visit, the medication itself and shipping.
altRX is silent on lab work and coaching.
Sipra is silent on lab work and coaching.
altRX
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
Sipra
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
Where each one scores higher
Overall they tie at 7.6 out of 10.
altRX is stronger on accessibility (10.0 vs 5.0).
Sipra is stronger on value (6.7 vs 5.0) and trust & safety (6.5 vs 6.0).
Effectiveness, user experience and support are within half a point.
altRX
7.6/10
Sipra
7.6/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
FDA warning letters
The FDA sent altRX a warning letter dated June 8, 2026 (letter 728236), and it is still open.
Sipra has no FDA warning letter on record with us.
Features & Coverage
| Feature | altRX | Sipra |
|---|---|---|
| Starting Price | $149/mo | $149/mo prepaid |
| Features | 8 features | 8 features |
| States Available | 50 | Not disclosed |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | ✓ Yes | — |
| FSA/HSA Accepted | — | ✓ Yes |
| FDA Warning Letters | 1 letter | ✓None |
About altRX
Compounded plans open at $149 for semaglutide and $249 for tirzepatide. Branded medication runs $1,149-$1,579, a figure that already contains the consult and the shipping. Every one of the four FDA-approved brands is stocked, Mounjaro, Ozempic, Wegovy and Zepbound, which no other entry in our directory matches. altRX works in both modalities, holds LegitScript certification, and prints the FDA compounded-medication disclaimer.
Read our full altRX review →About Sipra
Sipra is a Wyoming-registered telehealth platform whose prescribing runs through the MD Integrations physician network. It sells compounded semaglutide and tirzepatide as B12-blended weekly injections, dissolving tablets and microdose plans. Plans start at three months, paid upfront: semaglutide injections are $189 a month ($567) and tirzepatide $249 ($747), falling to $149 and $199 on a 12-month plan. You are charged only after a physician approves.
Read our full Sipra review →Pros & Cons
altRX
What we like
- Tirzepatide costs $1249 a month, close to the $1249 median for brand-name tirzepatide across the sellers we compare
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- The monthly price includes the medication, clinician visits and shipping
- Serves all 50 states
- Names 4 pharmacies that fill its prescriptions, which most sellers do not
Watch-outs
- Semaglutide costs $1149 a month, 15% above the $997 median for brand-name semaglutide across the sellers we compare
- The FDA has issued altRX a warning letter. Read what it alleges: a letter flags a problem but does not by itself rule a seller out
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Sipra
What we like
- Semaglutide costs $149 a month, 21% below the $188 median for compounded semaglutide across the sellers we compare
- Tirzepatide costs $199 a month, 20% below the $250 median for compounded tirzepatide across the sellers we compare
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- The monthly price stays the same as your dose goes up
- The monthly price includes the medication, clinician visits and shipping
- We found no FDA warning letters issued to Sipra
Watch-outs
- Confirm it serves your state before you start the intake
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Our Verdict
altRX and Sipra finish level at 7.6. Choose on the state list and on what each monthly price covers.
Choose altRX if…
You want semaglutide from $1149/month and an opening price near $149 a month.
Choose Sipra if…
You want people ready to prepay three months or more for compounded semaglutide or tirzepatide and an opening price near $149 a month.
Ready to start? GLP-1 providers we have vetted
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Luvo Health
Moving between compounded and brand without changing seller
From $249/mo
Get started →Strut Health
Semaglutide at $99/month, 48% below the typical price
From $99/mo
Get started →Enhance MD
Knowing which pharmacy fills the vial: it names Tru Meds Rx
From $169/mo
Get started →altRX vs Sipra: FAQ
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Or see the full category ranking.
Novo Nordisk A/S owns the Wegovy®, Ozempic® and Rybelsus® marks; Eli Lilly and Company owns Mounjaro® and Zepbound®. Every other product name and mark on this page belongs to whoever owns it. No pharmaceutical manufacturer is affiliated with GLP Watchdog. See trademark disclaimer.