Yes Clinic Review
Semaglutide & tirzepatide GLP-1 weight-loss telehealth · Independently scored 7.4/10
Best for: people ready to prepay three months for flat-priced compounded semaglutide or tirzepatide
Yes Clinic's strongest column is the clinical side: which molecules it will prescribe, and how it handles dosing.
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charged as a multi-month plan up front
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
Prices checked October 2026
Yes Clinic is an online clinic selling compounded semaglutide and tirzepatide shots alongside hormone, hair and sexual-health products. It sells GLP-1s only in 3- and 6-month plans paid up front: semaglutide works out to $129 a month ($387 per quarter) and tirzepatide $149 ($447). Its Terms of Use still contain unfilled template placeholders.
Is Yes Clinic legit?
Yes. Yes Clinic is a real, operating US company, and we found no FDA warning letters issued to it. We rate it 7.4/10 overall, across six areas from price to trust and safety. Legitimate is not the same as right for you, though: that part is a decision for you and a licensed clinician.
Is there a Yes Clinic promo or coupon code?
We know of no promo or coupon code for Yes Clinic. Its listed price is $129 a month. Coupon sites advertising "Yes Clinic discount codes" are not a source we can vouch for, and any genuine offer shows at checkout without a code.
See how Yes Clinic compares on our rankings of the best semaglutide providers and the best tirzepatide providers.
Vetted alternatives to Yes Clinic
CoreAge Rx
Best for: flat-priced compounded semaglutide at $79 a month, any dose
Editorial score · methodology
Editorial score · methodology
Editorial score · methodology
Yes Clinic at a glance
- Type
- GLP-1 telehealth provider
- Medications
- Semaglutide, Tirzepatide
- Starting price
- $129/mo
- Pricing model
- Flat: the price stays the same as the dose goes up
- What's included
- Medication · Consult · Shipping
- FDA status
- No FDA warning letters found
How Yes Clinic scores
Six columns, each one computed from something Yes Clinic has published rather than from an opinion we formed: what it charges, which molecules it will dispense, what its record shows, and what the monthly figure actually buys. Where a seller keeps something back, such as its price or its pharmacy, the score reflects it. Every seller we review goes through the same six columns.
Value25%
6.0/10$149/month is 40% below the $249 median for compounded tirzepatide across the sellers we compare. Every listed price requires paying for several months up front, so Value is capped at 6.
Effectiveness25%
10.0/10Dispenses semaglutide and tirzepatide, compounded only. Anchored to SURMOUNT-1 (tirzepatide, -20.9%) and STEP 1 (semaglutide, -14.9%).
User Experience15%
8.0/10A price is shown before the questionnaire starts.
Trust & Safety15%
6.5/10No pharmacy is named for its prescriptions. It shows a price before asking for health information.
Accessibility10%
5.0/10No state list is available to check, so this is held at the midpoint rather than scored on reach.
Support10%
7.0/10The price covers the medication, clinician visits and shipping.
A seller that shows no price until after the medical intake loses points on User Experience and Trust & Safety, and its review says so. How we score →
What we checked on Yes Clinic
Last checked October 2026- Checked the listed price across 2 dose or plan tiers
- Checked what the monthly price covers, and what it leaves out
- Checked FDA warning letters for Yes Clinic
Price, availability, and compliance here are read off the seller's own pages and off primary regulatory records, named in the sources below.
What signing up with Yes Clinic involves
What to expect on the way to a prescription: where the price appears, who fills the medication, and what the monthly price covers. It is not medical advice, and a clinician makes the prescribing decision.
- 1Yes Clinic shows a price on its own site before asking anything about you, so you can compare it with other sellers before you start a questionnaire.
- 2Ask Yes Clinic which pharmacy fills the prescription before you pay. The pharmacy's name is what lets you check its license.
- 3The monthly price includes the medication, clinician visits and shipping.
- Lowest ongoing monthly price: semaglutide $129, tirzepatide $149. That leaves out membership fees, first-month rates and insurance copays.
- Confirm that Yes Clinic serves your state before you start.
- The medication is compounded, so it is not an FDA-approved product and has not been reviewed by the agency for safety, effectiveness or manufacturing quality.
Contacting Yes Clinic
- Yes Clinic offers email support
Cancelling Yes Clinic
Taken from the terms Yes Clinic publishes. Terms change, so check the current policy before you subscribe.
- Cancel any time
- Yes
- Minimum commitment
- GLP-1 plans are 3 or 6 months, paid up front
- Refund policy
- No refunds on dispensed medication, even unopened. Full refund before dispensing, and replacement or refund for damaged, wrong or lost orders.
Medications Yes Clinic lists
Yes Clinic lists compounded semaglutide and compounded tirzepatide. Each one has its own guide: how it works, the dosing schedule, the side effects that show up in practice, and what the trials measured.
Pricing
Prices re-verified
$387 for 3 months, about $129 a month. A 6-month plan is $699 (about $116.50 a month). Same price at every dose. Consultation and shipping included.
$447 for 3 months, about $149 a month. The 6-month plan is $894, the same monthly rate. Same price at every dose.
Check the price yourself before you pay
Every figure here was read off Yes Clinic's own checkout on the date shown. Sellers move prices without announcing it, and promotional rates lapse, so confirm the standing cost on their site before committing.
In its favor
- Semaglutide costs $129 a month, 35% below the $199 median for compounded semaglutide across the sellers we compare
- Tirzepatide costs $149 a month, 40% below the $249 median for compounded tirzepatide across the sellers we compare
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- The monthly price stays the same as your dose goes up
- The monthly price includes the medication, clinician visits and shipping
- We found no FDA warning letters issued to Yes Clinic
Against it
- Confirm it serves your state before you start the intake
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
What Yes Clinic charges
The standing price at Yes Clinic is $129/month, unchanged as the dose goes up. Flat dose pricing matters more than it sounds: on a tiered plan the bill grows with the dose, so the figure that got you to sign up is not the one you end up paying.
- Compounded semaglutide: $129/month
- Compounded tirzepatide: $149/month
For compounded tirzepatide, the median across the sellers we compare is $249/month, so Yes Clinic's $149 is genuinely below the middle, not just advertised that way.
bmiMD, at about $129/month, is the closest like-for-like alternative we review.
What Yes Clinic dispenses
Yes Clinic prescribes semaglutide (approved as Wegovy and Ozempic) and tirzepatide (approved as Zepbound and Mounjaro). Between them these are the two molecules with the largest published weight-loss trial programs behind them. The medication is compounded rather than dispensed as an approved pen. Compounding serves real clinical needs and is entirely lawful; what it is not is reviewed, and the cost difference reflects that.
Safety and disclosure
Yes Clinic tells you its price before you start the medical questionnaire. We found no FDA warning letters issued to Yes Clinic. Because the medication is compounded, the most useful question to ask at intake is which licensed pharmacy fills the prescription. If Yes Clinic will not tell you, treat that as a warning sign. How we weigh oversight, disclosure and price is set out in our scoring methodology.
Who should look elsewhere
- You want the FDA-approved pen specifically. Everything listed here is compounded.
- You need insurance to cover the cost. Check whether Yes Clinic bills your plan before you start.
It fits if
- the lowest standing monthly cost is what you are solving for
- you want the price to stop moving as your dose climbs
Our read
Yes Clinic competes on price without an obvious sacrifice elsewhere: $149/month for compounded tirzepatide, no FDA warning letters.
The Bottom Line
Yes Clinic's strongest column is the clinical side: which molecules it will prescribe, and how it handles dosing.
Before you pay Yes Clinic
Starting at $129 a month. Check today's price, then start the intake.
Where Yes Clinic is the wrong choice
No seller suits every reader, and pretending otherwise is the easiest way to sell one. On these three counts, another seller does better.
- If you need the FDA-approved pen rather than a compounded vial, consider SkinnyRx.
- If the standing monthly cost is what decides it, consider Collective (from $59/mo).
- If you want a human checking in, not just a prescription, consider ShedRx.
Compare Yes Clinic head to head
The sellers closest to Yes Clinic on medication and price.
Frequently Asked Questions
How to check Yes Clinic yourself
Glossary
The words sellers use, defined. Tap any term.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Sources
Cited across this Yes Clinic review: primary regulatory filings, and peer-reviewed studies.
Sources & methodology — as of October 2026
- 1.GLP Watchdog — GLP-1 Pricing Index 2026 (our independent dataset)— GLP Watchdog.
- 2.FDA — Compounding and the 503A Pharmacy Framework— U.S. Food & Drug Administration.
- 3.FDA — Drug Shortages Database (current shortage listings)— U.S. Food & Drug Administration.
- 4.PCAB — Pharmacy Compounding Accreditation Board Standards— Accreditation Commission for Health Care (ACHC) / PCAB.
- 5.KFF — Medicaid coverage research (anti-obesity & GLP-1 drug policy)— Kaiser Family Foundation.
- 6.STEP 1 Trial — Once-Weekly Semaglutide in Adults with Overweight or Obesity (Wilding JPH et al.)— New England Journal of Medicine.PMID: 33567185.
- 7.FDA — Wegovy (semaglutide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
- 8.FDA — Ozempic (semaglutide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
- 9.SURMOUNT-1 Trial — Tirzepatide Once Weekly for the Treatment of Obesity (Jastreboff AM et al.)— New England Journal of Medicine.PMID: 35658024.
- 10.FDA — Zepbound (tirzepatide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
- 11.FDA — Mounjaro (tirzepatide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
- 12.SURMOUNT-5 Trial — Tirzepatide vs. Semaglutide Head-to-Head in Obesity (Garvey WT et al.)— New England Journal of Medicine.PMID: 40334173.
See Yes Clinic's current pricing
Plans start at $129 a month. Whether you qualify is a clinician's decision, made after your intake.