Guppy Meds Review
Semaglutide & tirzepatide GLP-1 weight-loss telehealth · Independently scored 6.5/10
Best for: shoppers who want compounded GLP-1s and peptides from one online store and accept limited disclosure
Guppy Meds scores highest on the clinical side (which drugs it prescribes and how it doses) and lowest on price. It charges from $219 a month; its compounded semaglutide, at $279, is 40% above the $199 median among the sellers we compare.
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Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
Prices checked November 2026
Guppy Meds is an online store based in Del Mar, California that sells compounded semaglutide, tirzepatide and liraglutide alongside a long list of peptides such as sermorelin, MOTS-c and epithalon. You pay at checkout before any provider visit. Semaglutide is $299 as a one-time purchase or $279 a month on auto-renew, and tirzepatide is $449 or $399. It does not name its pharmacy, and the doctors it lists could not be verified.
Is Guppy Meds legit?
Yes. Guppy Meds is a real, operating US company, and we found no FDA warning letters issued to it. We rate it 6.5/10 overall, across six areas from price to trust and safety. Legitimate is not the same as right for you, though: that part is a decision for you and a licensed clinician.
Is there a Guppy Meds promo or coupon code?
We know of no promo or coupon code for Guppy Meds. Its listed price is $219 a month. Coupon sites advertising "Guppy Meds discount codes" are not a source we can vouch for, and any genuine offer shows at checkout without a code.
See how Guppy Meds compares on our rankings of the best semaglutide providers and the best tirzepatide providers.
Vetted alternatives to Guppy Meds
Embody
Best for: a flat compounded tirzepatide or semaglutide price at every dose, from a seller that names its pharmacies
Editorial score · methodology
Editorial score · methodology
Editorial score · methodology
Guppy Meds at a glance
- Type
- GLP-1 telehealth provider
- Medications
- Semaglutide, Tirzepatide, Liraglutide
- Starting price
- $219/mo
- What's included
- Medication · Consult · Shipping
- FDA status
- No FDA warning letters found
How Guppy Meds scores
Six columns, each one computed from something Guppy Meds has published rather than from an opinion we formed: what it charges, which molecules it will dispense, what its record shows, and what the monthly figure actually buys. Where a seller keeps something back, such as its price or its pharmacy, the score reflects it. Every seller we review goes through the same six columns.
Value25%
2.6/10$279/month is 40% above the $199 median for compounded semaglutide across the sellers we compare. A cheaper microdose price is also listed; Value is scored on the standard dose.
Effectiveness25%
10.0/10Dispenses semaglutide and tirzepatide, compounded only. Anchored to SURMOUNT-1 (tirzepatide, -20.9%) and STEP 1 (semaglutide, -14.9%).
User Experience15%
8.0/10A price is shown before the questionnaire starts.
Trust & Safety15%
6.5/10No pharmacy is named for its prescriptions. It shows a price before asking for health information.
Accessibility10%
5.0/10No state list is available to check, so this is held at the midpoint rather than scored on reach.
Support10%
7.0/10The price covers the medication, clinician visits and shipping.
A seller that shows no price until after the medical intake loses points on User Experience and Trust & Safety, and its review says so. How we score →
What we checked on Guppy Meds
Last checked November 2026- Checked the listed price across 6 dose or plan tiers
- Checked what the monthly price covers, and what it leaves out
- Checked FDA warning letters for Guppy Meds
Price, availability, and compliance here are read off the seller's own pages and off primary regulatory records, named in the sources below.
What signing up with Guppy Meds involves
What to expect on the way to a prescription: where the price appears, who fills the medication, and what the monthly price covers. It is not medical advice, and a clinician makes the prescribing decision.
- 1Guppy Meds shows a price on its own site before asking anything about you, so you can compare it with other sellers before you start a questionnaire.
- 2Ask Guppy Meds which pharmacy fills the prescription before you pay. The pharmacy's name is what lets you check its license.
- 3The monthly price includes the medication, clinician visits and shipping.
- Lowest ongoing monthly price: semaglutide $219, tirzepatide $249. That leaves out membership fees, first-month rates and insurance copays.
- Confirm that Guppy Meds serves your state before you start.
- The medication is compounded, so it is not an FDA-approved product and has not been reviewed by the agency for safety, effectiveness or manufacturing quality.
Contacting Guppy Meds
- Phone
- 1-844-894-4888
- Guppy Meds offers email support
- Hours
- Monday to Friday, 9 AM to 5 PM Pacific
Cancelling Guppy Meds
Taken from the terms Guppy Meds publishes. Terms change, so check the current policy before you subscribe.
- Cancel any time
- Yes
- Minimum commitment
- None stated; the monthly plan auto-renews until canceled
- Refund policy
- FAQ: "we are unable to accept returns on dispensed prescription medications for safety reasons. If your order is lost in transit, arrives damaged, or if you are denied for medical reasons after payment, we will process a full refund. Consultation fees are non-refundable once a provider review has been completed."
Medications Guppy Meds lists
Guppy Meds lists compounded semaglutide and compounded tirzepatide. Each one has its own guide: how it works, the dosing schedule, the side effects that show up in practice, and what the trials measured.
Peptides Guppy Meds offers
Guppy Meds sells peptides beyond the GLP-1s. Tap one to read what the evidence says about it.
Pricing
Prices re-verified
Product page: "One-time purchase $299.00"; card tag "Same Price All Doses".
Product page: "Monthly Subscription $279.00 every month until canceled"; checkout: "Duration: Auto-renew until canceled".
"Semaglutide Microdose 0.250mg": "One-time purchase $249.00", "Monthly Subscription $219.00 every month until canceled".
Product page: "One-time purchase $449.00"; card tag "Same Price All Doses".
Product page: "Monthly Subscription $399.00 every month until canceled".
"Tirzepatide Microdose 2.5mg": "One-time purchase $299.00", "Monthly Subscription $249.00 every month until canceled".
Check the price yourself before you pay
Every figure here comes from Guppy Meds's own website, as of the date shown. Sellers move prices without announcing it, and promotional rates lapse, so confirm the standing cost on their site before committing.
In its favor
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- The monthly price includes the medication, clinician visits and shipping
- We found no FDA warning letters issued to Guppy Meds
Against it
- Semaglutide costs $279 a month, 40% above the $199 median for compounded semaglutide across the sellers we compare
- Tirzepatide costs $399 a month, 48% above the $269 median for compounded tirzepatide across the sellers we compare
- Confirm it serves your state before you start the intake
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
What Guppy Meds charges
Guppy Meds charges $219/month.
- Compounded semaglutide: $299/month
- Compounded semaglutide (monthly): $279/month
- Compounded semaglutide (microdose, monthly): $219/month
- Compounded tirzepatide: $449/month
- Compounded tirzepatide (monthly): $399/month
- Compounded tirzepatide (microdose, monthly): $249/month
For compounded semaglutide, the median across the sellers we compare is $199/month, so Guppy Meds' $279 is a premium, and a premium has to buy something. Check what is bundled before you accept it. Before you pay, compare Guppy Meds' cancellation terms with other sellers' cancellation and refund policies.
Belle Health dispenses semaglutide and tirzepatide from $199/month, which makes it the fair comparison to run before you commit here.
What Guppy Meds dispenses
Guppy Meds prescribes semaglutide (approved as Wegovy and Ozempic) and tirzepatide (approved as Zepbound and Mounjaro). Between them these are the two best-evidenced weight-loss molecules currently on the market. What arrives is compounded at a licensed pharmacy, not an approved pen. That is the reason it costs less, and the reason the finished preparation carries no FDA review behind it. The molecule can be the one in Ozempic and Wegovy; what differs is the formulation, the concentration and the dose ladder. Guppy Meds also lists a microdose plan, and the published evidence on GLP-1 microdosing is letters and commentary rather than trials.
Safety and disclosure
Guppy Meds tells you its price before you start the medical questionnaire. We found no FDA warning letters issued to Guppy Meds. Because the medication is compounded, the most useful question to ask at intake is which licensed pharmacy fills the prescription. If Guppy Meds will not tell you, treat that as a warning sign. A 503A pharmacy answers to a state board and a 503B facility to the FDA; which one fills it changes what you can check. How we weigh oversight, disclosure and price is set out in our scoring methodology.
Of the peptides Guppy Meds sells, Epitalon, Semax, and MOTS-c are among the six in the October 2026 HHS compounding policy. It says HHS does not intend to take enforcement action against 503A pharmacies that compound them under ten conditions, and it approves none of them.
Who should look elsewhere
- You care most about the twelve-month total, not the first bill. A flat-rate seller such as Collective will usually win that math.
- You want the FDA-approved pen specifically. Everything listed here is compounded.
- You need insurance to cover the cost. Check whether Guppy Meds bills your plan before you start.
Our read
Guppy Meds costs more than the middle of this market. If the extras it charges for are ones you would actually use, that is a defensible trade. If not, the same molecule is available for less.
The Bottom Line
Guppy Meds scores highest on the clinical side (which drugs it prescribes and how it doses) and lowest on price. It charges from $219 a month; its compounded semaglutide, at $279, is 40% above the $199 median among the sellers we compare.
Before you pay Guppy Meds
Starting at $219 a month. Check today's price, then start the intake.
Where Guppy Meds is the wrong choice
No seller suits every reader, and pretending otherwise is the easiest way to sell one. On these three counts, another seller does better.
- If you need the FDA-approved pen rather than a compounded vial, consider WellMedRx.
- If the standing monthly cost is what decides it, consider Collective (from $59/mo + membership).
- If you want a human checking in, not just a prescription, consider Eden.
If none of these fits, our guide to alternatives to Guppy Meds sets more sellers in the same category beside Guppy Meds on price, states and what the price includes.
Frequently Asked Questions
How to check Guppy Meds yourself
Glossary
The words sellers use, defined. Tap any term.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Sources
Cited across this Guppy Meds review: primary regulatory filings, and peer-reviewed studies.
Sources & methodology — as of November 2026
- 1.GLP Watchdog — GLP-1 Pricing Index 2026 (our independent dataset)— GLP Watchdog.
- 2.FDA — Compounding and the 503A Pharmacy Framework— U.S. Food & Drug Administration.
- 3.FDA — Drug Shortages Database (current shortage listings)— U.S. Food & Drug Administration.
- 4.PCAB — Pharmacy Compounding Accreditation Board Standards— Accreditation Commission for Health Care (ACHC) / PCAB.
- 5.KFF — Medicaid coverage research (anti-obesity & GLP-1 drug policy)— Kaiser Family Foundation.
- 6.STEP 1 Trial — Once-Weekly Semaglutide in Adults with Overweight or Obesity (Wilding JPH et al.)— New England Journal of Medicine.PMID: 33567185.
- 7.FDA — Wegovy (semaglutide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
- 8.FDA — Ozempic (semaglutide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
- 9.SURMOUNT-1 Trial — Tirzepatide Once Weekly for the Treatment of Obesity (Jastreboff AM et al.)— New England Journal of Medicine.PMID: 35658024.
- 10.FDA — Zepbound (tirzepatide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
- 11.FDA — Mounjaro (tirzepatide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
- 12.SURMOUNT-5 Trial — Tirzepatide vs. Semaglutide Head-to-Head in Obesity (Aronne LJ et al.)— New England Journal of Medicine.PMID: 40353578.
See Guppy Meds's current pricing
Plans start at $219 a month. Whether you qualify is a clinician's decision, made after your intake.