Tirzepatide for Menopause Weight Gain: 2026 Sellers — Ranked & Reviewed

Weight gained through perimenopause and menopause resists diet and exercise, and effort is not the variable: estrogen falls, lean mass goes with it, and energy expenditure follows. Tirzepatide does help (SURMOUNT-1 reached up to ~21% average body-weight loss), and plenty of women run it alongside hormone replacement therapy. Two things deserve more attention at this stage of life than at any other. Protecting muscle and bone through rapid loss, and keeping a GLP-1 and HRT under one prescriber instead of two who each see half.

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By Ruth Calder · Enforcement Editor
Editorially reviewed (not clinically reviewed). Not medical advice · How we verify contentLast reviewed

439 tirzepatide providers compared · independently scored against our six-factor methodology.

Price and states served both move. Read them off the seller's own site before you enroll.How our reviews work →

Methodology & sources

Each provider here carries a score from our published six-factor rubric[1], and the list is then cut down to the criteria named in the page title.

Published Phase 3 efficacy for tirzepatide (~20.9% mean weight loss at the 15 mg dose over 72 weeks) comes from the SURMOUNT-1 trial[2]. The SURMOUNT-5 head-to-head published in 2025 directly compared tirzepatide and semaglutide[3].

Quick Picks: Top 5

#ProviderScore
1Trimi HealthVisit
2EmbodyVisit
3bmiMDVisit
4CoreAge RxVisit
5Live VitalVisit

Detailed Reviews

1

Trimi Health

Verified partner

Best for: knowing which pharmacy fills the vial: it names VialsRx

9.4

Trimi Health is a telehealth seller whose compounded GLP-1 pricing is among the lowest available.

Score Breakdown

Value25%
10
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
10
Accessibility10%
10
Support10%
7
2

Embody

Verified partner

Best for: knowing which pharmacy fills the vial: it names RedRock Pharmacy

9.3

Embody sells compounded semaglutide and tirzepatide by injection, plus a compounded oral tirzepatide gum that is unique in the category. Flat-rate pricing is aggressive, coverage runs to all 50 states, and clinician messaging is available 24/7 under a board-certified internal medicine CMO.

Score Breakdown

Value25%
10
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
9
Accessibility10%
10
Support10%
7
3

bmiMD

Verified partner

Best for: starting below a standard dose, with microdose tiers

9.0

bmiMD is a medical weight loss clinic that prescribes GLP-1 medications through telehealth.

Score Breakdown

Value25%
9.5
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
8.5
Accessibility10%
10
Support10%
7
4

CoreAge Rx

Verified partner

Best for: semaglutide at $99/month, 48% below the typical price

9.0

Shipping is free, 2-day, and reaches all 50 states. CoreAge Rx sells LegitScript-verified compounded semaglutide plus tirzepatide, with licensed physicians behind it and 24/7 support. Its own claim: nobody in the compounded GLP-1 space prices more competitively.

Score Breakdown

Value25%
9.5
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
8.5
Accessibility10%
10
Support10%
7
5

Live Vital

Verified partner

Best for: semaglutide at $99/month, 48% below the typical price

9.0

Billed in 3-month blocks, the compounded GLP-1 semaglutide starts at $99/mo and compounded tirzepatide at $183/mo. Dr. Patrick Taylor, MD founded the practice and every plan is written by a doctor, filled at a licensed US pharmacy and delivered to the door. Messaging the care team has no cap and nothing locks you in. Peptide and hormone therapy round out the menu. Telehealth reaches all 50 states.

Score Breakdown

Value25%
9.5
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
8.5
Accessibility10%
10
Support10%
7
6

Gala

Verified partner

Best for: moving between compounded and brand without changing seller

8.7

A yearly subscription is the format: compounded semaglutide and compounded tirzepatide are sold that way, with a cheaper microdosing program beside them and brand-name Ozempic on the same menu. The corporate name is AI Coaching Inc., which does business as Gala GLP-1 and is incorporated in Delaware. Providers licensed in every one of the 50 states, plus shipping at no cost, are what the marketing site claims. A Wegovy pill taken orally is flagged as coming soon.

Score Breakdown

Value25%
8.7
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
7.5
Accessibility10%
10
Support10%
7
7

Found

Verified partner

Best for: tirzepatide at $169/month, 37% below the typical price

8.6

Found is a personalized weight care platform. It runs on a self-pay membership, and medication costs sit on top of that.

Score Breakdown

Value25%
7.8
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
8.5
Accessibility10%
10
Support10%
7
8

Collective

Verified partner

Best for: flat any-dose pricing, if you can absorb a $199 annual membership on top

8.4

Health For Everyone Inc., trading as CollectiveOS, sells compounded semaglutide at $59/mo and compounded tirzepatide at $69/mo on a membership model, with a mandatory $199 annual membership on top that the headline price does not include. It prices every dose the same, so the cost does not climb as the dose is titrated, and it does not require prepaying for medication. The site is marketed as being from the founder of Thrive Market. Neither its pharmacies nor its medical groups are named.

Score Breakdown

Value25%
10
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
6.5
Accessibility10%
5
Support10%
7
9

Enhance MD

Verified partner

Best for: knowing which pharmacy fills the vial: it names Tru Meds Rx

8.4

$112 buys the first month on Core, once $100 comes off the opening order with code SUMMER100. Core is the semaglutide tier, Advanced is tirzepatide, Elite combines the two. Before any of that, Enhance MD requires two mandatory steps: baseline metabolic labs, drawn at Quest Diagnostics, then a live video visit with a board-certified clinician. Most sellers in compounded GLP-1s onboard asynchronously and ask for neither, so this is the more rigorous route in.

Score Breakdown

Value25%
7.8
Effectiveness25%
10
User Experience15%
7
Trust & Safety15%
9
Accessibility10%
8.2
Support10%
7
10

Strut Health

Verified partner

Best for: semaglutide at $99/month, 48% below the typical price

8.4

Strut Health sells LegitScript and ACHC-accredited compounded semaglutide and tirzepatide in injectable and oral lozenge formats, shipping to 49 states. Board-certified US physicians handle prescribing and follow-up messaging is unlimited and free. Eligibility is gated behind a clinician determination of medical necessity that the company does not publicly define.

Score Breakdown

Value25%
9.5
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
4.5
Accessibility10%
9.8
Support10%
7
11

SnagRx

Verified partner

Best for: semaglutide at $99/month, 48% below the typical price

8.3

SnagRx runs a launch discount that puts compounded semaglutide at $99/mo and compounded tirzepatide at $149/mo, with pricing described as flat for life at the same price every dose. The cash-pay service comes from Modern Metabolic Medicine, Inc. and ships to the door in 1-2 days. No insurance and no membership; the telehealth visit and shipping are included.

Score Breakdown

Value25%
9.5
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
6.5
Accessibility10%
5
Support10%
7
12

YourEra

Verified partner

Best for: semaglutide at $99/month, 63% below the typical price

8.2

Injections of compounded semaglutide and compounded tirzepatide begin at $99 for the first month; what the price becomes after that is settled once the medical intake is done. Everything, doctor visits and prescriptions alike, happens remotely. YourEra carries LegitScript certification. To its credit the site says outright that what it sells is not Ozempic, Wegovy, Mounjaro or Zepbound, which is candid for this category.

Score Breakdown

Value25%
10
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
6.5
Accessibility10%
5
Support10%
5
13

Lttl

Verified partner

Best for: starting below a standard dose, with microdose tiers

8.0

Prepay for 12 months and compounded semaglutide drops to $129 with tirzepatide at $199; taken month to month they run $199/mo and $279/mo, one flat rate at any dose. Before checkout the entire price matrix is on view, every commitment length, form and medication in it. Longevity peptides and a microdose line at low dose fill out the direct-to-consumer catalog. The name is said aloud as little.

Score Breakdown

Value25%
8.7
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
6.5
Accessibility10%
5
Support10%
7
14

Oak

Verified partner

Best for: semaglutide at $119/month, 37% below the typical price

7.8

Oak sells compounded semaglutide and tirzepatide through telehealth. Oak Longevity Holdings Corp. operates the business, and prescriptions are issued through NVP Medical Group, P.A.

Score Breakdown

Value25%
8.2
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
6.5
Accessibility10%
5
Support10%
6
15

HealthRX

Verified partner

Best for: compounded semaglutide at $133/month

7.7

Three things are missing from the site: the name of the pharmacy doing the compounding, the roster of states where prescriptions are written, and any medical director. What is there is a LegitScript certificate, number 50087439, and the FDA's compounded-drug disclaimer. Prices hold steady whatever your dose, insurance plays no part, and overnight cold shipping costs nothing extra. A clinician licensed in the US turns around the brief online assessment inside 24 hours; if the answer is yes, a 503A compounder holding a license sends the semaglutide or tirzepatide within 24-48 hours.

Score Breakdown

Value25%
7.4
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
6.5
Accessibility10%
5
Support10%
7
16

MEDGm

Verified partner

Best for: month-to-month compounded semaglutide at $179 with the partner pharmacies named

7.4

MEDGm is a Delaware-registered telehealth platform selling compounded semaglutide and tirzepatide, with the clinical side run by OpenLoop Health providers. Month-to-month pricing is $179 for the semaglutide injection, $249 for an oral dissolving tablet and $279 for tirzepatide, each including the consultation, medication and shipping. Neither the drug name nor the plan ladder appears until you submit your name, email and phone. Brand Wegovy, Zepbound and Ozempic are advertised separately on a membership-plus-drug-cost basis.

Score Breakdown

Value25%
5.2
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
8
Accessibility10%
5
Support10%
7
17

RNK Health

Verified partner

Best for: an oral route if you will not self-inject

7.3

Des Moines, IA houses the medical operations of RNK Health, while pharmacy fulfillment happens in Springville, UT. The list pairs GLP-1s with longevity products: compounded tirzepatide, compounded semaglutide as injectable or oral, NAD+ in injectable, nasal, and liposomal form, a DNA Blueprint test panel, enclomiphene, and sermorelin.

Score Breakdown

Value25%
5
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
6.5
Accessibility10%
5
Support10%
8.5
18

Willow

Verified partner

Best for: seeing what it charges before you answer any medical questions

7.3

Tablets and injections are both on offer at Willow, a telehealth seller of compounded GLP-1 medications.

Score Breakdown

Value25%
3
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
9
Accessibility10%
7.6
Support10%
7
19

MyDrHank

Verified partner

Best for: an oral route if you will not self-inject

6.9

This entry covers the erectile-dysfunction side of MyDrHank, whose legal name is Dr. Hank, LLC. Four products sit on the list: sildenafil in generic form, tadalafil both generic and daily, and MDH Drive, which dissolves rapidly and pairs sildenafil with tadalafil. Every case gets reviewed online by providers holding U.S. licenses, and three partner pharmacies are named. Plans are itemized at one, three and six months, the cheapest being $25/mo for generic sildenafil, with free shipping and nothing to commit to.

Score Breakdown

Value25%
5.3
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
5.5
Accessibility10%
5
Support10%
5
20

Eden

Verified partner

Best for: coverage in all 50 states, which most sellers will not confirm

6.7

Eden is a premium telehealth platform. Its headline rates on both semaglutide and tirzepatide are promotional first-month prices.

Score Breakdown

Value25%
3
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
5.5
Accessibility10%
10
Support10%
4.5
21

RxSpan MD

Verified partner

Best for: knowing which pharmacy fills the vial: it names Belmar Pharmacy

6.7

RxSpan MD prices compounded semaglutide and tirzepatide from $249/mo, as injections or oral capsules, and also carries brand-name Wegovy, Zepbound and Ozempic. It is unusually transparent for the category: it names its 503A pharmacy partners, Belmar, Strive, Epiq Scripts and Casa Pharma, and its medical group. Shipping is free and unlimited 24/7 support is included. The physician-led practice was founded by Dr. John Diaz, a board-certified plastic surgeon, and is available in all 50 states.

Score Breakdown

Value25%
3
Effectiveness25%
10
User Experience15%
3
Trust & Safety15%
7.5
Accessibility10%
10
Support10%
8.5
22

Luvo Health

Verified partner

Best for: moving between compounded and brand without changing seller

6.6

Compounded and brand GLP-1s from LUVO HEALTH, INC., sold beside microdosing, longevity peptides, skincare, HRT and testosterone. Billing is in 4-week blocks.

Score Breakdown

Value25%
2.9
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
6.5
Accessibility10%
5
Support10%
7
23

Bodybuilding Health+

Verified partner

Best for: seeing what it charges before you answer any medical questions

6.4

Compounded semaglutide begins at $179/month, tirzepatide at $209/month; both sit toward the cheap end of the market. The platform is the telehealth arm of Bodybuilding.com, a fitness brand that has been around a long time, and it sells GLP-1s next to hormone, sexual-performance and metabolic-support programs, which suits a fitness-minded patient wanting one account. Clinicians licensed in the US write the prescriptions, and LegitScript has verified it.

Score Breakdown

Value25%
3
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
6.5
Accessibility10%
5
Support10%
5
24

Direct Meds

Verified partner

Best for: compounded semaglutide at $249/month

6.4

The FDA sent Direct Meds a warning letter in September 2025 over misleading marketing, and customers have reported a documented pattern of unexpected 3-month commitment charges. We list the company with both disclosed in full; read the warnings and the cons first. Its products are compounded semaglutide and tirzepatide, sold from Utah in injection and sublingual form.

Score Breakdown

Value25%
3.7
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
3.5
Accessibility10%
5
Support10%
7
25

ShedRx

Verified partner

Best for: oral orforglipron alongside the injectables

6.4

ShedRx is a telehealth seller with three formats of compounded GLP-1 medication: drops, lozenges, and injections.

Score Breakdown

Value25%
6.6
Effectiveness25%
10
User Experience15%
3
Trust & Safety15%
4
Accessibility10%
5
Support10%
7

414 more sellers we track for this

Ranked below the 25 above on the same rubric. Each links to its full review with current pricing.

We rank the list above the same way for every reader. What differs for menopause is the clinical context, and these evidence reviews go into it:

Frequently Asked Questions

Yes. The appetite and metabolic effects do not depend on estrogen status, and many women find it finally moves midsection weight that arrived with perimenopause and would not budge. Be clear about the limit of that: the pivotal trials were not designed around menopause, so this rests on mechanism and practice rather than a menopause-specific result.
Many women do, and no direct interaction is known. The two treat different things, HRT the hormonal symptoms and the GLP-1 the weight and metabolism, and some women find the pair works better than either on its own. Put both in front of one prescriber who can see your full history.
Some lean mass goes with rapid weight loss at any age, and it counts for more here, when bone and muscle are already declining. Protein intake and resistance training are the standard defense, and they work far better started at the outset than retrofitted later. Ask your provider what to monitor and how often.
Sources & methodology — as of September 2026
  1. 1.GLP Watchdog — GLP-1 Pricing Index 2026 (our independent dataset)— GLP Watchdog.
  2. 2.SURMOUNT-1 Trial — Tirzepatide Once Weekly for the Treatment of Obesity (Jastreboff AM et al.)— New England Journal of Medicine.PMID: 35658024.
  3. 3.SURMOUNT-5 Trial — Tirzepatide vs. Semaglutide Head-to-Head in Obesity (Garvey WT et al.)— New England Journal of Medicine.PMID: 40334173.