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ZestRx Review

Tirzepatide GLP-1 weight-loss telehealth · Independently scored 6.7/10

Best for: people in its few service states who want compounded tirzepatide from a named pharmacy, plus wellness shots

6.7
★★★☆☆6.7/10

ZestRx scores highest on the clinical side (which drugs it prescribes and how it doses) and lowest on price, and it serves 5 states. Its compounded tirzepatide costs $369 a month, paid up front, 37% above the $269 median among the sellers we compare.

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$369/mo

charged as a multi-month plan up front

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Not stated

Coaching

Not stated

See plans →

Prices checked November 2026

Compare top-rated alternatives ↓

ZestRx is a small telehealth service, formerly Zest Weight Loss, that prescribes compounded tirzepatide (made with vitamin B3) and sells sermorelin, NAD+, glutathione, B12 and MIC injections. It names its compounding pharmacy and serves only a handful of western and midwestern states. Tirzepatide is $399 for the first month with membership, or $369 a month on a 3-month plan paid up front.

By Ruth Calder · Enforcement Editor
Editorially reviewed. Not medical advice · How we verify contentLast reviewed
Price shown up frontIncludes medication + consult5 statesPharmacy namedNo FDA warning letters found

Is ZestRx legit?

ZestRx does not name the company behind it anywhere on its site or in its legal pages, so we could not confirm who you would be buying from. We found no FDA warning letters issued under the ZestRx name. We rate it 6.7/10 overall, across six areas from price to trust and safety. Find out who operates it before you pay, and raise any doubts with a licensed clinician.

Is there a ZestRx promo or coupon code?

We know of no promo or coupon code for ZestRx. Its listed price is $369 a month. Coupon sites advertising "ZestRx discount codes" are not a source we can vouch for, and any genuine offer shows at checkout without a code.

See how ZestRx compares on our rankings of the best tirzepatide providers.

Vetted alternatives to ZestRx

9.3/ 10
Verified partner

Embody

Best for: a flat compounded tirzepatide or semaglutide price at every dose, from a seller that names its pharmacies

★★★★★9.3/10

Editorial score · methodology

$79/mo
CompoundedSemaglutideTirzepatideGlutathioneNAD+
Get StartedRead full Embody review →
8.7/ 10
Verified partner

Eden

Best for: coverage in all 50 states, which most sellers will not confirm

★★★★☆8.7/10

Editorial score · methodology

$99/mo
CompoundedSemaglutideTirzepatideGHK-CuGlutathione
Get StartedRead full Eden review →
6.6/ 10
Verified partner

HumeCare+

Best for: an oral route if you will not self-inject

★★★☆☆6.6/10

Editorial score · methodology

$199/mo
CompoundedSemaglutideTirzepatide
Get StartedRead full HumeCare+ review →
ZestRx logo
6.7 / 10
Our editorial rating
Visit ZestRx →

from $369/mo · no insurance needed

ZestRx at a glance

Type
GLP-1 telehealth provider
Medications
Tirzepatide
Starting price
$369/mo
What's included
Medication · Consult · Shipping
Availability
5 states
FDA status
No FDA warning letters found

How ZestRx scores

Six columns, each one computed from something ZestRx has published rather than from an opinion we formed: what it charges, which molecules it will dispense, what its record shows, and what the monthly figure actually buys. Where a seller keeps something back, such as its price or its pharmacy, the score reflects it. Every seller we review goes through the same six columns.

Value25%

2.7/10

$369/month is 37% above the $269 median for compounded tirzepatide across the sellers we compare. Every listed price requires paying for several months up front.

Effectiveness25%

10.0/10

Dispenses tirzepatide, compounded only. Anchored to SURMOUNT-1 (tirzepatide, -20.9%).

User Experience15%

8.0/10

A price is shown before the questionnaire starts.

Trust & Safety15%

9.0/10

It names the pharmacy that fills its prescriptions. It shows a price before asking for health information. It lists the states it serves.

Accessibility10%

2.8/10

Serves 5 of 50 states.

Support10%

7.0/10

The price covers the medication, clinician visits and shipping.

6weighted dimensions
734sellers compared
Everychecked against the seller's own site
Value 25%Effectiveness 25%User Experience 15%Trust & Safety 15%Accessibility 10%Support 10%

A seller that shows no price until after the medical intake loses points on User Experience and Trust & Safety, and its review says so. How we score →

What we checked on ZestRx

Last checked November 2026
  • Checked the listed price across 2 dose or plan tiers
  • Checked state coverage: 5 states
  • Checked what the monthly price covers, and what it leaves out
  • Recorded which pharmacies the seller names as filling its prescriptions, with the page and date
  • Checked FDA warning letters for ZestRx

Price, availability, and compliance here are read off the seller's own pages and off primary regulatory records, named in the sources below.

What signing up with ZestRx involves

What to expect on the way to a prescription: where the price appears, who fills the medication, and what the monthly price covers. It is not medical advice, and a clinician makes the prescribing decision.

  1. 1ZestRx shows a price on its own site before asking anything about you, so you can compare it with other sellers before you start a questionnaire.
  2. 2Strive Pharmacy fills the prescriptions, and ZestRx names it publicly, which most sellers do not.
  3. 3The monthly price includes the medication, clinician visits and shipping.
Price shown before you start
  • Lowest ongoing monthly price: tirzepatide $369. That leaves out membership fees, first-month rates and insurance copays.
  • ZestRx serves 5 of 50 states, so check that yours is one of them.
  • The medication is compounded, so it is not an FDA-approved product and has not been reviewed by the agency for safety, effectiveness or manufacturing quality.

Contacting ZestRx

Email
ZestRx offers email support
Hours
Monday to Friday, 9am to 5pm

Cancelling ZestRx

Taken from the terms ZestRx publishes. Terms change, so check the current policy before you subscribe.

Minimum commitment
Monthly membership or a 3-month plan paid up front
Refund policy
Not published by the seller

Medications ZestRx lists

ZestRx lists compounded tirzepatide. Each one has its own guide: how it works, the dosing schedule, the side effects that show up in practice, and what the trials measured.

Tirzepatide(compounded)

Peptides ZestRx offers

ZestRx sells peptides beyond the GLP-1s. Tap one to read what the evidence says about it.

DropletGlutathioneAntioxidant infusionsDropletNAD+Energy & cellular agingSyringeSermorelinOwn growth-hormone output

Pricing

Prices re-verified

Monthly membership, first month (with niacinamide; consult, check-ins and delivery included)Compounded
$399/mo
tirzepatide

Tirzepatide FAQ: "At ZestRx, tirzepatide starts at $399 for your first month with membership. This includes your telehealth consult, ongoing provider check-ins, and medication delivery." The price after the first month is not stated.

3-month plan, $1,107 paid up front (with niacinamide)Compounded
$369/mo
tirzepatide

Tirzepatide page: "Starting at $369/month* ... *Paid upfront with a 3-month plan. Actual price to the will depend on the plan purchased." $1,107 is 3 x $369.

Check the price yourself before you pay

Every figure here comes from ZestRx's own website, as of the date shown. Sellers move prices without announcing it, and promotional rates lapse, so confirm the standing cost on their site before committing.

See ZestRx pricing →

ZestRx compounding-pharmacy partners

ZestRx names each pharmacy below as one that compounds or fills its prescriptions, in its own site, terms or filings. The quote under each one is the seller’s own wording.

Strive Pharmacy

“All prescriptions are filled by trusted, US-based compounding pharmacies ... Current pharmacy is Strive Pharmacy: 1275 E Baseline Rd #104, Gilbert, AZ 85233 (480) 626-4366”

Compare every compounding pharmacy we’ve reviewed →

In its favor

  • Shows its price before the medical questionnaire, so you can compare it without handing over health information
  • The monthly price includes the medication, clinician visits and shipping
  • Names Strive Pharmacy as the pharmacy that fills its prescriptions, which most sellers do not
  • We found no FDA warning letters issued to ZestRx

Against it

  • Tirzepatide costs $369 a month, 37% above the $269 median for compounded tirzepatide across the sellers we compare
  • Serves only 5 states, so check that yours is one of them
  • Its tirzepatide is compounded rather than FDA-approved, so it has not been reviewed by the agency for safety, effectiveness or manufacturing quality

What ZestRx charges

ZestRx charges $369/month. That sits above the middle of the market, which puts the burden on whatever else is in the package.

  • Compounded tirzepatide (monthly): $399 for the first month
  • Compounded tirzepatide (3-month plan): $369/month

For compounded tirzepatide, the median across the sellers we compare is $269/month, so ZestRx's $369 is a premium, and a premium has to buy something. Check what is bundled before you accept it. Some of ZestRx's plans are paid several months up front, so read the terms you agree to at checkout before you choose a longer one. For scale, the dearest tenth of compounded sellers charges about three times the cheapest tenth.

TrimRx dispenses tirzepatide from $299/month, which makes it the fair comparison to run before you commit here.

What ZestRx dispenses

ZestRx prescribes tirzepatide (approved as Zepbound and Mounjaro). That is among the best-evidenced options in this class. These are compounded preparations from a licensed pharmacy rather than approved pens, which is where the lower price comes from. A compounded drug is not FDA-approved as a finished product: the specific preparation has not been reviewed for safety, efficacy or manufacturing quality. What FDA has reported about compounded tirzepatide covers the safety record so far.

Safety and disclosure

ZestRx tells you its price before you start the medical questionnaire, the 5 states it serves, and the pharmacy that fills its prescriptions. We found no FDA warning letters issued to ZestRx. Because the medication is compounded, the named pharmacy is the detail that matters most: its license is the one you can look up. The FDA publishes seven warning signs for telehealth medicine sellers, and they take a minute to run against ZestRx. How we weigh oversight, disclosure and price is set out in our scoring methodology.

ZestRx also sells NAD+, and a 2026 systematic review found no outcomes trials of injected NAD+ for anti-aging or wellness.

Who should look elsewhere

  • You care most about the twelve-month total, not the first bill. A flat-rate seller such as Collective will usually win that math.
  • You want the FDA-approved pen specifically. Everything listed here is compounded.
  • You need insurance to cover the cost. Check whether ZestRx bills your plan before you start.

Our read

ZestRx costs more than the middle of this market. If the extras it charges for are ones you would actually use, that is a defensible trade. If not, the same molecule is available for less.

The Bottom Line

ZestRx scores highest on the clinical side (which drugs it prescribes and how it doses) and lowest on price, and it serves 5 states. Its compounded tirzepatide costs $369 a month, paid up front, 37% above the $269 median among the sellers we compare.

Score: 6.7/10Best for: people in its few service states who want compounded tirzepatide from a named pharmacy, plus wellness shotsFrom: $369/mo

Before you pay ZestRx

Starting at $369 a month. Check today's price, then start the intake.

Visit ZestRx →

Where ZestRx is the wrong choice

No seller suits every reader, and pretending otherwise is the easiest way to sell one. On these three counts, another seller does better.

  • If you need the FDA-approved pen rather than a compounded vial, consider WellMedRx.
  • If the standing monthly cost is what decides it, consider Collective (from $59/mo + membership).
  • If you want a human checking in, not just a prescription, consider Eden.

If none of these fits, our guide to alternatives to ZestRx sets more sellers in the same category beside ZestRx on price, states and what the price includes.

Frequently Asked Questions

ZestRx is a small telehealth service, formerly Zest Weight Loss, that prescribes compounded tirzepatide (made with vitamin B3) and sells sermorelin, NAD+, glutathione, B12 and MIC injections. It names its compounding pharmacy and serves only a handful of western and midwestern states. Tirzepatide is $399 for the first month with membership, or $369 a month on a 3-month plan paid up front. We rate it 6.7/10 overall.
ZestRx starts at $369 a month. The pricing table above lists every tier.
ZestRx names 5 states. Check that yours is on the list before you go any further.
ZestRx lists compounded tirzepatide.
ZestRx lists compounded GLP-1s only. A licensed compounding pharmacy prepares them: same active ingredient as the brand drug, lower cash price, and no FDA approval of the finished product. That last part is the one readers underestimate, and the review above says why.
Check whether ZestRx bills your insurance before you sign up. It also takes FSA and HSA cards. Compounded GLP-1s are rarely covered by insurance, so plan on paying the listed cash price.
ZestRx says the price covers medication, the clinician visit and shipping. The strip near the top of this review shows what is included and what is not.
You fill in an online intake, a licensed clinician decides whether a GLP-1 is appropriate, and if the answer is yes the medication ships to you. ZestRx runs that whole sequence on its own site.
We found no FDA warning letters issued to ZestRx. Before you buy, weigh these: Tirzepatide costs $369 a month, 37% above the $269 median for compounded tirzepatide across the sellers we compare. Serves only 5 states, so check that yours is one of them. Its tirzepatide is compounded rather than FDA-approved, so it has not been reviewed by the agency for safety, effectiveness or manufacturing quality. None of them rules ZestRx out, but each is worth settling before you pay.
Other sellers we cover include TrimRx, RxSpan MD, and Direct Meds. Which one fits depends on the medication, the monthly price you can sustain and whether it ships to your state, so compare those three facts before you switch.

How to check ZestRx yourself

Every seller that ships to your state, side by side: Arizona, Colorado, Illinois, Montana, Washington.

Glossary

The words sellers use, defined. Tap any term.

Sources

Cited across this ZestRx review: primary regulatory filings, and peer-reviewed studies.

Sources & methodology — as of November 2026
  1. 1.GLP Watchdog — GLP-1 Pricing Index 2026 (our independent dataset)— GLP Watchdog.
  2. 2.FDA — Compounding and the 503A Pharmacy Framework— U.S. Food & Drug Administration.
  3. 3.FDA — Drug Shortages Database (current shortage listings)— U.S. Food & Drug Administration.
  4. 4.PCAB — Pharmacy Compounding Accreditation Board Standards— Accreditation Commission for Health Care (ACHC) / PCAB.
  5. 5.KFF — Medicaid coverage research (anti-obesity & GLP-1 drug policy)— Kaiser Family Foundation.
  6. 6.SURMOUNT-1 Trial — Tirzepatide Once Weekly for the Treatment of Obesity (Jastreboff AM et al.)— New England Journal of Medicine.PMID: 35658024.
  7. 7.FDA — Zepbound (tirzepatide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
  8. 8.FDA — Mounjaro (tirzepatide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.

See ZestRx's current pricing

Plans start at $369 a month. Whether you qualify is a clinician's decision, made after your intake.

Visit ZestRx →