GLP Watchdog

Best Tirzepatide for Men in 2026: Ranked and Reviewed

Men lose a smaller share of their body weight than women on GLP-1 drugs. In the six trials that reported weight loss by sex, covering 19,906 patients, men lost 6.8% on average and women 10.9%, according to a 2026 review in JAMA Internal Medicine that pooled semaglutide and older GLP-1 drugs, not tirzepatide. Three things are worth knowing before you pick a seller. Low testosterone often travels with obesity, and losing weight can lift it with no hormone involved. The evidence on erectile function points in both directions. And running a GLP-1 alongside testosterone replacement therapy (TRT) is common enough that your prescriber needs to know about both.

Some of the links on this page earn us money. If you sign up with a provider after following one, that provider may pay GLP Watchdog a commission. Learn more

By Ruth Calder · Enforcement Editor
Editorially reviewed. Not medical advice · How we verify contentLast reviewed

598 tirzepatide providers compared · independently scored against our six-factor methodology.

Price and states served both move. Read them off the seller's own site before you enroll.How our reviews work →

Methodology & sources

Each provider here carries a score from our published six-factor rubric[1], and the list is then cut down to the criteria named in the page title.

Published Phase 3 efficacy for tirzepatide (~20.9% mean weight loss at the 15 mg dose over 72 weeks) comes from the SURMOUNT-1 trial[2]. The SURMOUNT-5 head-to-head published in 2025 directly compared tirzepatide and semaglutide[3].

Quick Picks

Starting price per provider. Prices in USD per month; checked November 2026.
#ProviderScore
1EmbodyVisit
2SnagRxVisit
3CollectiveVisit
4CoreAge RxVisit
5LttlVisit

What the trials show for men

The men's evidence is thinner than the women's. These are the figures our research desk has checked, with a note on each saying which drug was actually studied.

  • 6.8% vs 10.9%

    average weight lost, men vs women, older GLP-1 drugs

    In the six trials that reported weight loss by sex (19,906 patients), men lost 6.8% of body weight on average and women 10.9%. The review's trials tested semaglutide, liraglutide, exenatide, lixisenatide and dulaglutide; tirzepatide was not among them.[4]

    Who loses more weight →

  • RR 0.70

    erectile dysfunction risk, tirzepatide vs sitagliptin

    In a database study of men with type 2 diabetes, tirzepatide was linked to a lower risk of erectile dysfunction than every comparator: a risk ratio of 0.70 against sitagliptin and 0.67 against injectable semaglutide. It is retrospective and randomized nothing, and a diagnosis partly measures how often a man sees a doctor.[5]

    Erectile function evidence →

  • 2% to 4%

    normally shaped sperm on semaglutide, not tirzepatide

    The randomized comparison with TRT used semaglutide. In 25 men with type 2 diabetes, obesity and low testosterone, semaglutide raised normally shaped sperm from 2% to 4%, while TRT cut sperm concentration and total count. Both raised total testosterone. It ran open-label, so treat it as a reason to ask, not a plan.[6]

Detailed Reviews

1

Embody

Verified partner

Best for: a flat compounded tirzepatide or semaglutide price at every dose, from a seller that names its pharmacies

9.3

Embody is the brand Modern Metabolic Medicine, Inc. runs through its JoinEm storefront. It sells compounded semaglutide and tirzepatide injections at one price per drug at every dose, $79 and $129 for a one-month supply, plus a compounded oral tirzepatide gum. You pay at checkout, before an OpenLoop Health clinician decides on a prescription, and payments are final.

Score Breakdown

Value25%
10
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
9
Accessibility10%
10
Support10%
7
Starting from $129/moRead full review →
Visit Embody →
2

SnagRx

Verified partner

Best for: semaglutide at $99/month, well below the typical price

9.2

SnagRx sells compounded semaglutide at $99 a month and compounded tirzepatide at $149 a month on its 1-month plan, one price at every dose. Longer plans cut the monthly rate but are charged in full up front and are non-refundable. Clinicians come from the OpenLoop Health network; the platform is Modern Metabolic Medicine, Inc. The visit and 1-2 day shipping are included, with no insurance and no membership.

Score Breakdown

Value25%
10
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
9
Accessibility10%
9.8
Support10%
7
Starting from $149/moRead full review →
Visit SnagRx →
3

Collective

Verified partner

Best for: flat any-dose pricing, if you can absorb a $199 annual membership on top

9.1

Health For Everyone Inc., trading as CollectiveOS, sells compounded semaglutide at $59/mo and compounded tirzepatide at $69/mo on a membership model, with a mandatory $199 annual membership on top that the headline price does not include. It prices every dose the same, so the cost does not climb as the dose is titrated, and it does not require prepaying for medication. The site is marketed as being from the founder of Thrive Market. Neither its pharmacies nor its medical groups are named.

Score Breakdown

Value25%
10
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
9
Accessibility10%
9
Support10%
7
Starting from $69/moRead full review →
Visit Collective →
4

CoreAge Rx

Verified partner

Best for: flat-priced compounded semaglutide at $79 a month, any dose

9.0

CoreAge Rx charges the same amount at every dose of its compounded GLP-1s: semaglutide is $79 a month, tirzepatide $129. Consult and shipping are inside that figure, and there is no membership fee. You pay before a doctor reviews the case, and every prescription sale is final once it reaches the pharmacy.

Score Breakdown

Value25%
10
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
7.5
Accessibility10%
9.7
Support10%
7
Starting from $129/moRead full review →
Visit CoreAge Rx →
5

Lttl

Verified partner

Best for: starting below a standard dose, with microdose tiers

9.0

Lttl sells compounded semaglutide at $99 a month and tirzepatide at $149 a month on its month-to-month plan, one flat price at any dose. Prepaying for 12 months lowers those to $89 and $139. Every price and commitment length is on a public plans page before checkout. A microdose line at $149 a month and longevity peptides fill out the catalog.

Score Breakdown

Value25%
10
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
7.5
Accessibility10%
10
Support10%
7
Starting from $149/moRead full review →
Visit Lttl →
6

YourEra

Verified partner

Best for: semaglutide at $99/month, well below the typical price

9.0

YourEra sells compounded semaglutide and compounded tirzepatide injections through an online visit with a licensed clinician, at one price for every dose. It is run by Your Era Management, L.L.C. in Louisiana, and it names its medical group and its three pharmacies. Semaglutide is $99 a month month-to-month. Tirzepatide is published only as a 12-month prepaid plan averaging $99 a month.

Score Breakdown

Value25%
10
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
7.5
Accessibility10%
10
Support10%
7
Starting from $99/moRead full review →
Visit YourEra →
7

altRX

Verified partner

Best for: compounded semaglutide from $89/month at the same price at every dose

8.8

Compounded plans open at $89 for semaglutide and $149 for tirzepatide, the same at every dose. Branded medication runs $1,149-$1,579, a figure that already contains the consult and the shipping. Every one of the four FDA-approved brands is stocked, Mounjaro, Ozempic, Wegovy and Zepbound, which no other entry in our directory matches. altRX works in both modalities, holds LegitScript certification, and prints the FDA compounded-medication disclaimer. FDA sent its operator a warning letter in June 2026.

Score Breakdown

Value25%
10
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
6
Accessibility10%
10
Support10%
7
Starting from $149/moRead full review →
Visit altRX →
8

Eden

Verified partner

Best for: coverage in all 50 states, which most sellers will not confirm

8.7

Eden sells compounded semaglutide and tirzepatide through its own pharmacy network and a contracted provider group. Its price pages promise the same charge at every dose and say there is no membership fee. Its own terms still describe a $39-then-$99 monthly membership with medication billed on top. Semaglutide is $99 a month and tirzepatide $129.

Score Breakdown

Value25%
10
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
4.5
Accessibility10%
10
Support10%
8.5
Starting from $129/moRead full review →
Visit Eden →
9

Strut Health

Verified partner

Best for: semaglutide at $99/month, well below the typical price

8.6

Strut Health sells LegitScript and ACHC-accredited compounded semaglutide and tirzepatide in injectable and oral lozenge formats, shipping to 49 states. Board-certified US physicians handle prescribing and follow-up messaging is unlimited and free. Eligibility is gated behind a clinician determination of medical necessity that the company does not publicly define.

Score Breakdown

Value25%
10
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
4.5
Accessibility10%
9.8
Support10%
7
Starting from $149/moRead full review →
Visit Strut Health →
10

Gala

Verified partner

Best for: moving between compounded and brand without changing seller

8.5

A yearly plan is the format: compounded semaglutide and compounded tirzepatide are sold that way, with brand-name Ozempic on the same menu. The corporate name is AI Coaching Inc., which does business as Gala GLP-1 and is incorporated in Delaware; care comes through OpenLoop-affiliated medical groups. Compounded GLP-1 is $179 a month on the yearly plan, all doses included. A Wegovy pill taken orally is flagged as coming soon.

Score Breakdown

Value25%
7.9
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
7.5
Accessibility10%
10
Support10%
7
Starting from $179/moRead full review →
Visit Gala →

Ranked 11 to 30

The same ranking continues in short form: each seller's score, the lowest standing price we hold, and a link to its full review.

  1. 11
    bmiMDVerified partner

    From $179/mo

    8.2
  2. 12
    HealthRXVerified partner

    From $214/mo

    8.2
  3. 13
    Live VitalVerified partner

    From $239/mo

    8.2
  4. 14
    Sesame CareVerified partner

    From $299/mo

    8.1
  5. 15
    PlexusDxVerified partner

    From $99/mo

    8.0
  6. 16
    Sprout HealthVerified partner

    From $149/mo

    8.0
  7. 17
    Belle HealthVerified partner

    From $249/mo

    7.9
  8. 18
    Luvo HealthVerified partner

    From $179/moOffers testosterone therapy (seller's page, read Oct 30, 2026)

    7.9
  9. 19
    RxSpan MDVerified partner

    From $329/mo

    7.9
  10. 20
    ShedRxVerified partner

    From $299/mo

    7.9
  11. 21
    AgelessRxVerified partner

    From $209/mo

    7.4
  12. 22
    WellorithmVerified partner

    From $349/mo

    7.4
  13. 23
    FoundVerified partner

    From $299/mo

    7.3
  14. 24
    Ivim HealthVerified partner

    From $192/mo

    7.3
  15. 25
    MEDGmVerified partner

    From $269/mo

    7.3
  16. 26
    OakVerified partner

    From $300/mo

    7.2
  17. 27
    Direct MedsVerified partner

    From $299/mo

    7.1
  18. 28
    DudeMedsVerified partner

    From $233/moOffers testosterone therapy (seller's page, read Oct 30, 2026)

    6.8
  19. 29
    GoodLife HealthVerified partner

    From —

    6.8
  20. 30
    HumeCare+Verified partner

    From $299/mo

    6.6

568 more sellers we track for this

Ranked below the 30 above on the same rubric. Each links to its full review with current pricing.

← See all Tirzepatide Providers

Men-specific research

We rank the list above the same way for every reader. What differs for men is the clinical context, and these evidence reviews go into it:

Frequently Asked Questions

Yes. Men were in every pivotal trial and lost a clinically meaningful amount of weight. As a share of body weight they lose less than women: 6.8% against 10.9% across six trials analyzed by sex, none of them tirzepatide trials. Starting heavier does not close that gap, since baseline BMI made no significant difference to kilograms lost across 15 trials. Dose escalation runs on the same schedule.
Many men do. TRT treats low testosterone, and the GLP-1 treats appetite and weight. One difference matters if you may want children: in a 25-man randomized trial, TRT cut sperm concentration and total count, while semaglutide raised the share of normally shaped sperm. Obesity suppresses testosterone, so retest after the weight comes off rather than assuming it moved in either direction. Keep both under one prescriber.
Testosterone, indirectly. In men whose low testosterone is driven by excess weight, losing the weight can lift it, and in the 25-man trial total testosterone rose on semaglutide as well as on TRT. Erectile function is less clear: database studies point in both directions, and in that trial erectile scores improved significantly only on TRT. No hormone is in the drug, and it is not a treatment for either problem. Report any change to your prescriber.
Sources & methodology — as of November 2026
  1. 1.GLP Watchdog — GLP-1 Pricing Index 2026 (our independent dataset)— GLP Watchdog.
  2. 2.SURMOUNT-1 Trial — Tirzepatide Once Weekly for the Treatment of Obesity (Jastreboff AM et al.)— New England Journal of Medicine.PMID: 35658024.
  3. 3.SURMOUNT-5 Trial — Tirzepatide vs. Semaglutide Head-to-Head in Obesity (Aronne LJ et al.)— New England Journal of Medicine.PMID: 40353578.
  4. 4.Heterogeneity of Treatment Effects of GLP-1 Receptor Agonists for Weight Loss in Adults: A Systematic Review and Meta-Analysis (Alexander GC et al.)— JAMA Internal Medicine.PMID: 41770554.
  5. 5.Association of tirzepatide with erectile dysfunction in people with type 2 diabetes (Cowart K et al.)— Journal of Diabetes and Its Complications.PMID: 40614622.
  6. 6.Semaglutide improved sperm morphology in obese men with type 2 diabetes mellitus and functional hypogonadism (Gregorič N et al.)— Diabetes, Obesity and Metabolism.PMID: 39511836.