Zepbound for Sleep Apnea Sellers in 2026: Ranked and Reviewed
Zepbound is the only drug FDA has approved for obstructive sleep apnea, and the approval is narrow: adults with obesity whose apnea is moderate to severe, with a reduced-calorie diet and more activity alongside it. This board lists only sellers whose price list names brand Zepbound. Compounded tirzepatide is the same molecule but carries no sleep apnea indication and was not what the sleep apnea trials tested, so it is left off. A sleep study, not a seller's intake form, establishes whether your apnea is moderate to severe.
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80 tirzepatide providers compared · independently scored against our six-factor methodology.
Methodology & sources
Each provider here carries a score from our published six-factor rubric[1], and the list is then cut down to the criteria named in the page title.
Published Phase 3 efficacy for tirzepatide (~20.9% mean weight loss at the 15 mg dose over 72 weeks) comes from the SURMOUNT-1 trial[2]. The SURMOUNT-5 head-to-head published in 2025 directly compared tirzepatide and semaglutide[3].
Quick Picks
Zepbound and sleep apnea: the record
From the SURMOUNT-OSA trials, the Zepbound label and FDA's approval notice, each read on October 30, 2026.
25.3 and 29.3
fewer breathing events an hour at week 52
In the two SURMOUNT-OSA trials, tirzepatide at 10 or 15 mg cut the apnea-hypopnea index by 25.3 events an hour in people not using a breathing machine and by 29.3 in people who were. Placebo cut it by 5.3 and 5.5.[4]
What the trials found →51.5 to about 26
events an hour, trial 1 average
Trial 1 started from an average of 51.5 events an hour, in the severe range. Subtracting the average fall leaves about 26, which is still moderate apnea. The average participant improved a great deal and still had the condition at week 52.[4]
10 or 15 mg
the label's sleep apnea dose
Zepbound's label sets 10 mg or 15 mg once a week as the maintenance dose for sleep apnea, reached in 2.5 mg steps from a 2.5 mg start at least four weeks apart.[5]
Which Zepbound dose works best →Dec 20, 2024
FDA's sleep apnea approval
On December 20, 2024, FDA cleared Zepbound to treat obstructive sleep apnea of moderate or severe grade in adults who also have obesity, and called it the first drug treatment option for those patients.[6]
Sleep apnea and GLP-1 treatment →
Detailed Reviews
altRX
Verified partnerBest for: compounded semaglutide from $89/month at the same price at every dose
Compounded plans open at $89 for semaglutide and $149 for tirzepatide, the same at every dose. Branded medication runs $1,149-$1,579, a figure that already contains the consult and the shipping. Every one of the four FDA-approved brands is stocked, Mounjaro, Ozempic, Wegovy and Zepbound, which no other entry in our directory matches. altRX works in both modalities, holds LegitScript certification, and prints the FDA compounded-medication disclaimer. FDA sent its operator a warning letter in June 2026.
Score Breakdown
Sesame Care
Verified partnerBest for: oral orforglipron alongside the injectables
Sesame sells a care subscription, $59 to $99 a month, and nothing in it pays for the drug. Medication is brand-name only and billed at the maker's cash price: Wegovy pill and Foundayo from $149, Zepbound from $299 through LillyDirect, and a $199 Wegovy or Ozempic intro for new self-pay patients. Patients pick an independent provider from a marketplace rather than a house clinic.
Score Breakdown
Luvo Health
Verified partnerBest for: moving between compounded and brand without changing seller
Compounded and brand GLP-1s from Luvo Health, Inc., sold beside a microdosing program and longevity peptides; skincare, HRT and testosterone are listed as coming soon. Billing is in 4-week blocks. Compounded semaglutide injections cost $209 per 4 weeks after a half-price first cycle, and microdose plans cost $179.
Score Breakdown
RxSpan MD
Verified partnerBest for: knowing which pharmacy fills the vial: it names Belmar Pharmacy
RxSpan MD prices compounded semaglutide and tirzepatide from $249/mo, as injections or oral capsules, and also carries brand-name Wegovy, Zepbound and Ozempic. It is unusually transparent for the category: it names its 503A pharmacy partners, Belmar, Strive, Epiq Scripts and Casa Pharma, and its medical group. Shipping is free and unlimited 24/7 support is included. The physician-led practice was founded by Dr. John Diaz, a board-certified plastic surgeon, and is available in all 50 states.
Score Breakdown
ShedRx
Verified partnerBest for: oral orforglipron alongside the injectables
ShedRx (Shed) sells compounded semaglutide as weekly injections, liquid drops and lozenges, plus compounded tirzepatide injections, at one price for every dose. It also arranges brand Wegovy, Zepbound and Foundayo for a separate monthly membership. Compounded semaglutide injections and lozenges start at $199 a month; the cheaper 6- and 12-month rates are paid up front.
Score Breakdown
Wellorithm
Verified partnerBest for: compounded semaglutide at a flat $247 every 28 days, any dose
Wellorithm is a Miami GLP-1 telehealth seller that serves all 50 states and D.C. It publishes flat prices for compounded semaglutide and tirzepatide injections, the same at every dose, and also lists brand Wegovy, Ozempic, Zepbound and Mounjaro. Compounded semaglutide costs $147 for the first month, then $247 every 28 days.
Score Breakdown
Found
Verified partnerBest for: people who want clinician visits billed to commercial insurance, with compounded medication in the plan price
Found is a weight-care program with board-certified clinicians, coaching and an app. Its compounded plans bundle medication and membership at one price per dose, billed every 4 weeks. Brand-name drugs are billed separately from the membership. Month to month, compounded semaglutide is $289 and tirzepatide $359; the $169 rate on its pricing page requires 12 months paid up front.
Score Breakdown
MEDGm
Verified partnerBest for: compounded semaglutide with every plan price published and the partner pharmacies named
MEDGm is a Delaware-registered telehealth platform selling compounded semaglutide and tirzepatide, with OpenLoop Health named as the provider network. Month to month, semaglutide injections are $299, the oral dissolving tablet $369 and tirzepatide $399, after a discounted first month of $179, $249 or $279. Plans of 3, 6 or 12 months billed up front run lower, down to $169 a month for semaglutide. Brand Wegovy, Zepbound and Ozempic are advertised on a membership-plus-drug-cost basis.
Score Breakdown
Oak
Verified partnerBest for: a choice of compounded injections, oral semaglutide and brand-name GLP-1s from one cash-pay checkout
Oak is a cash-pay telehealth seller of compounded GLP-1 shots, a compounded oral semaglutide and brand-name GLP-1s. Leaf Longevity Holdings Corp. operates it as Oak Longevity, and NVP Medical Group prescribes. Compounded semaglutide lists at $250 a month and tirzepatide at $300 at the starting dose, before a checkout code. Its own FAQ says each dose step adds about $50 to $75.
Score Breakdown
DudeMeds
Verified partnerBest for: compounded semaglutide at $175/month, prepaid as a 3-month kit
Compounded semaglutide starts at $175 a month and compounded tirzepatide at $233, each sold as a prepaid kit covering two to four months, with free shipping, no doctor fee and no membership fee. DudeMeds is a telehealth platform for men that also sells hair loss, ED and TRT treatments, and it accepts clinic-switch patients who come from an existing GLP-1 and TRT provider.
Score Breakdown
SkinnyRx
Verified partnerBest for: starting below a standard dose, with microdose tiers
SkinnyRx sells compounded semaglutide and tirzepatide as weekly injections and daily tablets, with a microdose option, plus brand-name Ozempic, Wegovy, Mounjaro and Zepbound. Compounded injections are advertised at $99 for the first month; the rate from month two is not published before intake. Brand pens are listed at $1,400 a month, and the Wegovy and Foundayo pills from $248 a month through its membership. The company received an FDA warning letter in February 2026.
Score Breakdown
WellMedRx
Verified partnerBest for: comparing compounded and brand GLP-1 plans with a published state list
WellMedr, now styled welludr., advertises compounded semaglutide from $49 a month and tirzepatide from $89, but its own billing policy says a per-month figure on a prepaid plan is the total divided by the months, and the real plan terms appear only at checkout. Brand Ozempic and Zepbound are offered month to month. Three Florida pharmacies are named, and service covers all 50 states plus DC, Puerto Rico and Guam.
Score Breakdown
Tryozi
Best for: coverage in all 50 states, which most sellers will not confirm
Tryozi Group LLC, of Pembroke Pines, Florida, sells compounded semaglutide at $79 a month and tirzepatide at $129, billed monthly and sold as a lifetime deal against struck-through prices of $279 and $379. One price applies at every dose, and it covers the consult, base labs and shipping. It names its four 503A pharmacies, and also lists brand Ozempic at $1,299 and Zepbound at $1,399.
Score Breakdown
Brightmeds
Best for: flat-priced compounded GLP-1s with TRT and peptides on the same account
Brightmeds sells compounded semaglutide at $129 and tirzepatide at $149 a month, the same at any dose, or $99 and $119 a month on a 3-month pack paid up front. Those prices are for new patients in 38 states and DC and stay locked while the plan runs. It also sells TRT, sermorelin, NAD+ and glutathione, and writes Zepbound vial prescriptions for a $100 consult fee, with LillyDirect billing the drug.
Score Breakdown
LillyDirect
Best for: brand-name Zepbound or Foundayo bought from the manufacturer at a posted cash price
LillyDirect is Eli Lilly's own pharmacy channel for Zepbound (tirzepatide) and the Foundayo (orforglipron) daily tablet. It fills a valid US prescription from any prescriber and can connect you with independent telehealth doctors. Self-pay Zepbound vials and KwikPens cost $299 at 2.5 mg, $399 at 5 mg and $449 at higher doses when you refill within 45 days. Self-pay Foundayo runs $149 to $299 a month by dose. Commercially insured patients with coverage can pay as little as $25 a month.
Score Breakdown
PreventiveMD
Best for: oral orforglipron alongside the injectables
PreventiveMD sells compounded semaglutide and tirzepatide at one price per plan length, whatever the dose, with shipping and provider review included. Month to month, semaglutide is $119 and tirzepatide $139; the advertised $83 and $97 are 12-month plans paid up front. Brand Wegovy, Zepbound and Foundayo carry a $49 monthly membership, with the drug bought from the maker. A US-licensed provider reviews each request in writing within 24 to 48 hours, and it names its four compounding pharmacies.
Score Breakdown
Aspire Health
Best for: a published price you can check dose by dose before handing over any health information
Aspire Health is a Nebraska‑based telehealth practice that publishes dose‑by‑dose prices before any intake. Compounded semaglutide works out to about $103/month at 0.5 mg and $184 at the 2.4 mg maintenance dose; compounded tirzepatide is about $249/month at 5 mg. Brand Wegovy and Zepbound are priced separately. Medication is billed on top of a $49 medical‑care fee charged every 28 days, and the cost of lab work is not included. A named PA/NP team prescribes, and all three dispensing pharmacies are named publicly.
Score Breakdown
Remedy Well
Best for: people who want low posted prices on compounded or oral tirzepatide, with peptides from the same clinic
Remedy Well is an online clinic that prescribes compounded semaglutide and tirzepatide, mixed with vitamin B12 or glycine, plus tirzepatide tablets, a microdose plan and $59-a-month access memberships for Zepbound and Wegovy. It also sells sermorelin, NAD+, glutathione and GHK-Cu. Semaglutide is $149 a month and tirzepatide $169, each with a discounted first month, or tirzepatide is $399 for a 3-month bundle.
Score Breakdown
Walgreens Weight Management
Best for: brand-name Wegovy, Zepbound or Foundayo at manufacturer self-pay prices, filled at Walgreens
Walgreens Weight Management is Walgreens' online GLP-1 clinic for brand-name Wegovy, Zepbound and Foundayo, with each visit $49 and no subscription. Medication is billed separately: with a manufacturer savings card, self-pay starts at $149 a month for the Wegovy pill or Foundayo, and Zepbound pens run $299 to $449. It serves every state except Alabama and Louisiana.
Score Breakdown
Astra
Best for: people ready to prepay a year of compounded semaglutide or tirzepatide for one of the lowest monthly rates
Astra is an online clinic that prescribes compounded semaglutide and tirzepatide, brand-name Wegovy, Ozempic and Zepbound, and sermorelin, NAD+ and glutathione, through a named Florida medical group and named 503A pharmacies. Plans are paid up front and renew automatically: semaglutide is $145 a month or $68 a month on a 12-month plan billed $816 at once, and tirzepatide is $250 a month or $118 a month on the 12-month plan, at any dose.
Score Breakdown
Navio MD
Best for: moving between compounded and brand without changing seller
NavioMD, Inc. sells compounded tirzepatide at $189 a month for doses up to 7.5 mg and $209 above that, and brand-name Zepbound from $445 a month at 2.5 mg, rising to $595 at higher doses. Ozempic and Mounjaro are no longer offered. The Pharmacy Hub fills every prescription, a LegitScript seal is shown, and the FAQ now claims all 50 states. It also sells women's hormone support and longevity injectables.
Score Breakdown
FORM
Best for: choosing among plain, B12-glycine, tablet and microdose GLP-1 formats in one place
FORM by GBY is a Las Vegas telehealth brand from GBY Beauty that sells compounded semaglutide from $159 a month and tirzepatide from $219, after a cheaper first month. It also sells a FORM3 blend with B12 and glycine, dissolving tablets and a $199 microdose tirzepatide plan. Wegovy and Zepbound need a $95 monthly membership, with the drug billed separately. Prescribing runs through Architek Health and Ovie Health Group. Cancel anytime.
Score Breakdown
Vytora Health
Best for: moving between compounded and brand without changing seller
Compounded semaglutide is $179 a month, or $149 a month on a 3-month plan billed $447; compounded tirzepatide is $249 a month, or $199 on a 3-month plan billed $599. Brand Mounjaro and Zepbound are $1,399 a month. It serves all 50 states and DC. It names its pharmacies, Vials Pharmacy and Hallandale Pharmacy, and its medical group, Wasef Health, PC.
Score Breakdown
Gentle Health
Best for: people who want dose-tiered compounded GLP-1 prices or brand GLP-1s at maker prices from one named doctor
Gentle Health is a Little Rock, Arkansas telehealth clinic whose one named physician prescribes compounded semaglutide and tirzepatide, or Wegovy, Zepbound and Foundayo bought from the makers. Compounded care is priced by dose tier, from $135 a month for semaglutide and $169 for tirzepatide, with medication, the doctor and refrigerated shipping included. Brand care is $28 a month plus the maker's price. It names its three pharmacies and serves 40 states and DC.
Score Breakdown
Pallas Health
Best for: knowing which pharmacy fills the vial: it names Belmar Pharmacy
Pallas Health, run by Brentmoor, Inc., sells compounded semaglutide at $199 and tirzepatide at $299 every 4 weeks, the same at every dose, after a first month of $139 or $179. Provider care, messaging and shipping are included, and nothing is charged until a clinician prescribes. Brand Wegovy, Ozempic, Zepbound, Mounjaro, the Wegovy pill and Foundayo sell cash-pay. It names Lion MD, two physicians with NPIs and four pharmacies, and serves all 50 states plus DC.
Score Breakdown
55 more sellers we track for this
Ranked below the 25 above on the same rubric. Each links to its full review with current pricing.
- Effecty
- OrderlyMeds
- GOAL.MD
- NuuVim
- HuHealth
- Wellya
- GoodRx
- Heally
- Phoenix NP
- Tomorrow
- XMD Wellness
- GobyMeds
- MEDVi
- RxION Health
- WePeptideRx
- HeliMeds
- Peptivo
- Knownwell
- NoBsRx
- ElixaMD
- Ro
- Heva Health
- Maximus
- Corsica Health
- Imbue Health
- Measured
- Mochi Health
- Wisp
- Alloy
- Amazon One Medical
- Healthspan
- KairoRx
- Kin Meds
- WeightWatchers Clinic
- Elara Women's Wellness
- Good Girl Rx
- Immortals
- Layla
- BiltRx
- Hims
- Nucific
- The Virtual NP
- Intermountain Health On-Demand Weight Loss
- Sculpt Rx
- médetone
- Ora Medical Clinic
- Josie
- Aquivia Health
- AskRx
- LifeMD
- ZipHealth
- Fridays
- Noom
- Remmy
- WeightWatchers
Related research
The list above shows who sells brand Zepbound. These pages cover the trials, the condition itself, and how to get the drug covered for sleep apnea.
Frequently Asked Questions
Sources & methodology — as of November 2026
- 1.GLP Watchdog — GLP-1 Pricing Index 2026 (our independent dataset)— GLP Watchdog.
- 2.SURMOUNT-1 Trial — Tirzepatide Once Weekly for the Treatment of Obesity (Jastreboff AM et al.)— New England Journal of Medicine.PMID: 35658024.
- 3.SURMOUNT-5 Trial — Tirzepatide vs. Semaglutide Head-to-Head in Obesity (Aronne LJ et al.)— New England Journal of Medicine.PMID: 40353578.
- 4.SURMOUNT-OSA Trials: Tirzepatide for the Treatment of Obstructive Sleep Apnea and Obesity (Malhotra A et al.)— New England Journal of Medicine.PMID: 38912654.
- 5.Zepbound (tirzepatide) prescribing information, DailyMed SPL— Eli Lilly and Company, via the National Library of Medicine (DailyMed).
- 6.FDA Approves First Medication for Obstructive Sleep Apnea (press announcement, December 20, 2024)— U.S. Food and Drug Administration.