Sublingual Semaglutide Sellers in 2026: Ranked and Reviewed

There is no FDA-approved sublingual semaglutide. The approved semaglutide pills, Rybelsus, Ozempic tablets and the Wegovy pill, are swallowed on an empty stomach and depend on an absorption enhancer called SNAC. Drops, troches, lozenges and tablets that dissolve in the mouth are compounded products, and we found no published study measuring how much semaglutide from them reaches the blood in people. Every seller below lists a compounded semaglutide price for one of those forms.

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By Ruth Calder · Enforcement Editor
Editorially reviewed. Not medical advice · How we verify contentLast reviewed

63 compounded semaglutide providers compared · independently scored against our six-factor methodology.

Price and states served both move. Read them off the seller's own site before you enroll.How our reviews work →

Methodology & sources

Each provider here carries a score from our published six-factor rubric[1], and the list is then cut down to the criteria named in the page title.

Published Phase 3 efficacy for semaglutide 2.4 mg (~14.9% mean weight loss over 68 weeks) comes from the STEP 1 trial[2]. The SURMOUNT-5 head-to-head published in 2025 directly compared tirzepatide and semaglutide[3].

Quick Picks

Starting price per provider. Prices in USD per month; checked November 2026.
#ProviderScore
1Strut HealthVisit
2ShedRxVisit
3MEDGmVisit
4Direct MedsVisit
5MangoRxVisit

Sublingual semaglutide: the evidence so far

From the semaglutide tablet labels, the one published animal study and our own literature search, each read on October 30, 2026.

  • No human study

    of sublingual absorption

    We found no published human study measuring how much semaglutide from drops, lozenges or dissolving tablets reaches the blood, which means a drop dose cannot be converted to an injection dose.

    What we searched for →
  • 0.34%

    of injected exposure, in rats

    In a 2026 rat study, sublingual semaglutide reached 0.34% of the exposure of an injection under the skin, against 0.06% for the same dose swallowed. The authors called for studies in humans before drawing conclusions.[4]

  • Swallowed

    how the approved tablets are taken

    Rybelsus and Ozempic tablets are swallowed once daily before any food, with half a cup (4 oz) of plain water at most, and the wait before eating, drinking or other pills is at least 30 minutes. The Wegovy pill follows the same rule. None is approved to dissolve under the tongue.[5]

    How the approved pills work →

Detailed Reviews

1

Strut Health

Verified partner

Best for: semaglutide at $99/month, well below the typical price

8.6

Strut Health sells LegitScript and ACHC-accredited compounded semaglutide and tirzepatide in injectable and oral lozenge formats, shipping to 49 states. Board-certified US physicians handle prescribing and follow-up messaging is unlimited and free. Eligibility is gated behind a clinician determination of medical necessity that the company does not publicly define.

Score Breakdown

Value25%
10
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
4.5
Accessibility10%
9.8
Support10%
7
2

ShedRx

Verified partner

Best for: oral orforglipron alongside the injectables

7.9

ShedRx (Shed) sells compounded semaglutide as weekly injections, liquid drops and lozenges, plus compounded tirzepatide injections, at one price for every dose. It also arranges brand Wegovy, Zepbound and Foundayo for a separate monthly membership. Compounded semaglutide injections and lozenges start at $199 a month; the cheaper 6- and 12-month rates are paid up front.

Score Breakdown

Value25%
5
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
7.5
Accessibility10%
10
Support10%
8.5
3

MEDGm

Verified partner

Best for: compounded semaglutide with every plan price published and the partner pharmacies named

7.3

MEDGm is a Delaware-registered telehealth platform selling compounded semaglutide and tirzepatide, with OpenLoop Health named as the provider network. Month to month, semaglutide injections are $299, the oral dissolving tablet $369 and tirzepatide $399, after a discounted first month of $179, $249 or $279. Plans of 3, 6 or 12 months billed up front run lower, down to $169 a month for semaglutide. Brand Wegovy, Zepbound and Ozempic are advertised on a membership-plus-drug-cost basis.

Score Breakdown

Value25%
2.2
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
9
Accessibility10%
10
Support10%
7
4

Direct Meds

Verified partner

Best for: compounded semaglutide at $249/month

7.1

The FDA sent Direct Meds a warning letter in September 2025 over misleading marketing, and customers have reported a documented pattern of unexpected 3-month commitment charges. We list the company with both disclosed in full; read the warnings and the cons first. It sells compounded semaglutide and tirzepatide as shots or under-the-tongue drops, from $249 a month on a 90-day supply.

Score Breakdown

Value25%
4.2
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
4.5
Accessibility10%
9.7
Support10%
7
5

MangoRx

Verified partner

Best for: an oral route if you will not self-inject

6.5

MangoRx is the men's health brand of Mangoceuticals, Inc. Its only GLP-1 product, Slim, is compounded oral semaglutide with vitamin B6 in a mint dissolving tablet; there is no injection and no tirzepatide. The same platform sells ED, hair loss and testosterone treatment. Slim costs $299 a month, billed monthly, with the provider visit and shipping included.

Score Breakdown

Value25%
2.1
Effectiveness25%
8.5
User Experience15%
8
Trust & Safety15%
7.5
Accessibility10%
9.4
Support10%
5.5
6

Rewinding RX

Best for: compounded semaglutide at one $139 monthly price for any dose, with microdose and drop options

8.8

Rewinding RX is a longevity telehealth platform that sells compounded GLP-1s at one monthly price for any dose: $139 for semaglutide and $189 for tirzepatide. Microdose plans run $119 and $169, sublingual drops $139 and $169, and tirzepatide with NAD+ $199. It says it serves all 50 states and that only MDs review cases, though its FAQ says the network also includes nurse practitioners. The pharmacies are not named.

Score Breakdown

Value25%
8.4
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
8.5
Accessibility10%
10
Support10%
7
7

HealthHub

Best for: a low posted price on compounded semaglutide with no subscription to cancel

8.6

HealthHub sells compounded GLP-1s with one-time, no-subscription pricing that includes the consult, medication, supplies and shipping. Semaglutide injection is $99 a month, a sublingual version $149, and tirzepatide injection $199. Oral dissolving tablets of both drugs are listed without a price. Orders are filled by Redrock and Vios, the two pharmacies its drug pages list with addresses. The homepage also claims an in-house pharmacy, which it never names.

Score Breakdown

Value25%
10
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
8
Accessibility10%
5
Support10%
7
8

Riovie

Best for: people who want posted prices for compounded semaglutide or tirzepatide as a shot or a sublingual tablet

8.5

Riovie is an online clinic that prescribes compounded semaglutide and tirzepatide as a weekly injection or a daily under-the-tongue tablet, alongside menopause hormone therapy and longevity treatments such as sermorelin, NAD+ and glutathione. It names its medical group and its compounding pharmacy and publishes its state list. Injectable semaglutide is $149 for one month or $345 for a 3-month plan; tirzepatide is $209 or $585.

Score Breakdown

Value25%
7.1
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
9
Accessibility10%
10
Support10%
7
9

FORM

Best for: choosing among plain, B12-glycine, tablet and microdose GLP-1 formats in one place

8.4

FORM by GBY is a Las Vegas telehealth brand from GBY Beauty that sells compounded semaglutide from $159 a month and tirzepatide from $219, after a cheaper first month. It also sells a FORM3 blend with B12 and glycine, dissolving tablets and a $199 microdose tirzepatide plan. Wegovy and Zepbound need a $95 monthly membership, with the drug billed separately. Prescribing runs through Architek Health and Ovie Health Group. Cancel anytime.

Score Breakdown

Value25%
6.6
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
9
Accessibility10%
9.7
Support10%
7
10

Try Ageless

Best for: compounded semaglutide from $99/month, by injection or under the tongue

8.4

Try Ageless sells compounded semaglutide and tirzepatide in four formats: weekly injection, sublingual drops, troche and a dissolving tablet. Semaglutide injection starts at $99 a month and rises with the dose to $229; a $50 coupon applies to the first order. The platform frames itself around longevity and metabolic health and holds LegitScript certification.

Score Breakdown

Value25%
10
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
8
Accessibility10%
5
Support10%
4.5
11

YOURx Health

Best for: an oral route if you will not self-inject

8.4

YOURx Health, operated by YOURx Health LLC of Beaumont, TX, sells compounded semaglutide and tirzepatide with B12 as weekly injections or rapid-dissolve tablets. Injections are $159 a month for semaglutide and $179 for tirzepatide; tablets are $139 and $159. Care runs through MD Integrations with a physician video visit, and it is self-pay only. Its FAQ says it serves every state but Mississippi.

Score Breakdown

Value25%
8.8
Effectiveness25%
10
User Experience15%
7.5
Trust & Safety15%
7.5
Accessibility10%
9.8
Support10%
5
12

Found Youth

Best for: people who want microdose, sublingual or standard compounded GLP-1 plans priced in full up front

8.3

Found Youth is a physician-founded online apothecary offering compounded semaglutide and tirzepatide in weekly shots, low-dose microdose plans and sublingual drops, alongside peptides and skin care. It names its medical group and pharmacy and lists 50 states. Month to month, semaglutide shots are $199 and tirzepatide $279; microdose plans start at $149.

Score Breakdown

Value25%
6.2
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
9
Accessibility10%
10
Support10%
7
13

Nova

Best for: Texas and Florida patients who want all-in pricing with the monthly membership included

8.3

NovaCure LLC, trading as Nova, now serves only Texas and Florida. It charges a $50 monthly Nova Care membership and bills medication separately, and its weight-loss pages quote all-in starting prices of $127 a month for daily sublingual semaglutide or tirzepatide and $152 for weekly semaglutide injections. Its own pages give conflicting figures for the same products. It names its medical director and nurse practitioner.

Score Breakdown

Value25%
10
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
7.5
Accessibility10%
2.3
Support10%
7
14

Harmon Health

Best for: people who want posted prices for compounded GLP-1 shots, tablets or starter doses, or the Wegovy pill

8.1

Harmon Health is a new online clinic run by Harmon DTC Inc., formed in January 2026, which licenses the Harmon name from its parent company, owner of the former Harmon health and beauty store chain. It prescribes compounded semaglutide and tirzepatide as weekly shots, low-dose starter plans and dissolving tablets, plus the Wegovy pill, sermorelin, NAD+ and glutathione. Shots are $149 a month for semaglutide and $225 for tirzepatide at every dose, with a Black Friday first month of $99. Tablets start at $52 a month.

Score Breakdown

Value25%
10
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
6.5
Accessibility10%
5
Support10%
4.5
15

Edessa

Best for: compounded semaglutide by injection or tablet at one price per dose, with pharmacies named

8.0

Edessa is a cash-pay telehealth weight-loss service from Edessa Group, LLC of Las Vegas, with prescribing handled by OpenLoop Health's clinician network. It sells compounded semaglutide as a weekly injection or a daily dissolving tablet, plus compounded tirzepatide, at the same price at every dose, and it names four partner pharmacies. Month to month, the semaglutide injection is $179, the tablet $229 and tirzepatide $239; the advertised $135 is the 6-month plan rate.

Score Breakdown

Value25%
5.9
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
7.5
Accessibility10%
10
Support10%
7
16

ElitePhysiqMD

Best for: a live video visit with a physician before any GLP-1 prescription

7.9

ElitePhysiqMD, now at a new web address, sells compounded semaglutide at $219 for 4 weeks and tirzepatide from $249, rising with dose to $389. Each one-time order adds a $49 video visit and, after the first order, $30 shipping. Members pay 10% less per refill and no visit or shipping fees, but membership costs $89 a month. A board-certified internist, Hridayesh Nat, MD, is the named medical director.

Score Breakdown

Value25%
5.6
Effectiveness25%
10
User Experience15%
7.5
Trust & Safety15%
7.5
Accessibility10%
10
Support10%
7
17

IonicMD

Best for: people who want posted prices for compounded GLP-1 injections, a daily tablet or a microdose program

7.9

IonicMD is an online clinic that prescribes compounded semaglutide and tirzepatide as weekly injections, plus a daily semaglutide tablet, low-dose microdose programs, NAD+ and sermorelin. Care comes from clinicians affiliated with a national telehealth medical group, and the terms name four partner pharmacies. Month-to-month plans are $249 for semaglutide and $279 for tirzepatide, billed every 4 weeks; longer plans and the microdose programs start at $179.

Score Breakdown

Value25%
4.7
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
9
Accessibility10%
10
Support10%
7
18

Recovery Delivered

Best for: an oral route if you will not self-inject

7.9

Recovery Delivered sells compounded semaglutide injections at $199.99 a month for the first three months, rising to $299.99 at the top dose, and compounded tirzepatide from $219.99 at 2.5 mg to $489.99 at 12.5 and 15 mg. Oral semaglutide drops or tablets are $249. Each price includes a video visit with a provider, supplies and delivery. Tara Healthcare LLC runs it beside an addiction-treatment line, in 31 states and DC.

Score Breakdown

Value25%
6.5
Effectiveness25%
10
User Experience15%
7.5
Trust & Safety15%
8.5
Accessibility10%
7
Support10%
7
19

TelePeptide

Best for: needle-free compounded GLP-1 tablets with every plan price shown up front

7.9

TelePeptide sells compounded semaglutide and tirzepatide by direct pay, as weekly injections or dissolvable tablets, with the clinician evaluation, prescription, medication and shipping in one price. Semaglutide injection is $199 a month month to month, or $169 a month on an annual plan paid up front; tirzepatide is $249, or $214. It serves 48 states and DC, not Alaska or Mississippi, and shows a LegitScript seal.

Score Breakdown

Value25%
5.6
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
7.5
Accessibility10%
9.7
Support10%
7
20

VigoreMD

Best for: people who want a simple one-time-purchase compounded GLP-1 plan with a dedicated coach and no subscription

7.9

VigoreMD is a Florida telehealth brand, launched in 2026, that sells two compounded GLP-1 programs with a dedicated care coach: a daily semaglutide dissolving tablet for $199 a month and weekly tirzepatide injections for $299. Each order is a one-time purchase with no subscription. Clinicians come from its pharmacy partner's prescriber network, and neither the pharmacy nor the prescribers are named.

Score Breakdown

Value25%
5
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
7.5
Accessibility10%
9.4
Support10%
8.5
21

Breeze Meds

Best for: knowing which pharmacy fills the vial: it names Belmar Pharmacy

7.8

Breeze Meds is a Georgia-based telehealth seller shipping to all 50 states, with compounded semaglutide at $199/mo, tirzepatide at $399/mo, and NAD+ at $169/mo. It is LegitScript certified, names its medical team (Dr. Ana Lisa Carr MD and Dr. Kelly Tenbrink MD), and works through a 4-pharmacy compounding network via Lion MD: Belmar, Strive, Epiq Scripts, and Casa Pharma Rx.

Score Breakdown

Value25%
5
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
9
Accessibility10%
10
Support10%
4.5
22

NexLife

Best for: compounded semaglutide at one price per dose, with named pharmacies and coaching included

7.8

NexLife is a LegitScript-certified telehealth platform selling compounded semaglutide at $139 a month and tirzepatide at $169, the same at every dose, with no membership. Longer plans cut the rate to $119 and $139 on 12 months. It also sells microdose and under-the-tongue tablet versions of both. NexLife Medical Group prescribes, and Absolute Pharmacy, Premium Compounding and Boudreaux's New Drug Store fill.

Score Breakdown

Value25%
8.4
Effectiveness25%
10
User Experience15%
7.5
Trust & Safety15%
5
Accessibility10%
5
Support10%
8.5
23

Raeliva

Best for: a needle-free oral tablet at one price for every dose

7.8

Raeliva, run by Pacific Shores Research Group, LLC of San Diego, sells compounded semaglutide and tirzepatide as a weekly shot or a tablet dissolved under the tongue each day, priced the same at any dose. Month to month, semaglutide injections cost $219 and tirzepatide $299; 3- and 6-month plans are cheaper but charged in one payment. Prescribers come from Lion MDs, and the FAQ names six dispensing pharmacies.

Score Breakdown

Value25%
4.3
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
9
Accessibility10%
10
Support10%
7
24

StaveMD

Best for: compounded semaglutide or tirzepatide from named pharmacies with a no-weight-loss refund

7.8

StaveMD is the trading name of RZ International LLC, a California company that sells compounded GLP-1s through OpenLoop Health's clinician network and names four dispensing pharmacies. Semaglutide injections start at $179 a month, a dissolving semaglutide tablet at $199 and tirzepatide at $249, with no membership fee. Plans renew every four weeks, and a guarantee refunds every payment if you take the drug as prescribed and lose no weight.

Score Breakdown

Value25%
5.8
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
7.5
Accessibility10%
10
Support10%
5
25

Tomorrow

Best for: compounded semaglutide or tirzepatide by injection or drops, from a seller that names its pharmacies

7.8

Tomorrow is a self-pay telehealth service from Tomorrow Health LLC that offers compounded semaglutide and tirzepatide in three forms (weekly shots, lower-dose shots and under-the-tongue drops), plus brand Wegovy and Zepbound. It names its medical group, its two pharmacies and the lead physician's NPI. Paid monthly, compounded semaglutide is $199 and tirzepatide $299; the lower 'from' prices it shows are averages of a 3-month charge.

Score Breakdown

Value25%
5
Effectiveness25%
10
User Experience15%
8
Trust & Safety15%
7.5
Accessibility10%
10
Support10%
7

The list above shows who sells mouth-dissolving semaglutide. These pages cover the evidence and the approved pills it is often confused with.

Frequently Asked Questions

No one has shown that they do in people. We found no human study of how much semaglutide from drops reaches the blood, and the one animal study found exposure under 1% of an injection's. Some users report weight loss; that is not the same as a measured dose.
No. The Wegovy pill is an FDA-approved tablet that is swallowed and contains SNAC to help absorption. Sublingual drops and dissolving tablets are compounded, not approved, and have no human absorption data.
Not reliably. Without human absorption data, a milligram under the tongue cannot be matched to a milligram injected. Ask the prescriber how the dose was chosen and how they will judge whether it is working.
They are compounded drugs, prepared by a pharmacy on a prescription, and are not FDA-approved. FDA has warned that it does not check a compounded GLP-1 for quality, safety or effect before a patient receives it.
The table shows each seller's price for its mouth-dissolving form, with the date we checked it. Compare it with the same seller's vial price on its review before you choose a form for cost.
Sources & methodology — as of November 2026
  1. 1.GLP Watchdog — GLP-1 Pricing Index 2026 (our independent dataset)— GLP Watchdog.
  2. 2.STEP 1 Trial — Once-Weekly Semaglutide in Adults with Overweight or Obesity (Wilding JPH et al.)— New England Journal of Medicine.PMID: 33567185.
  3. 3.SURMOUNT-5 Trial — Tirzepatide vs. Semaglutide Head-to-Head in Obesity (Aronne LJ et al.)— New England Journal of Medicine.PMID: 40353578.
  4. 4.Single-dose pharmacokinetics of sublingual semaglutide in rats (Liu Y et al.)— European Journal of Pharmaceutical Sciences.PMID: 41386332.
  5. 5.Rybelsus and Ozempic (semaglutide) tablets prescribing information, DailyMed SPL— Novo Nordisk, via the National Library of Medicine (DailyMed).