SUMMIT

What is SUMMIT?

Tirzepatide in heart failure with preserved ejection fraction plus obesity (Packer et al., NEJM 2025), with substantial improvement in HFpEF-specific outcomes.

The tirzepatide counterpart to STEP-HFpEF.

Related reading: SUMMIT: Tirzepatide in Heart Failure

GLP Watchdog writes these definitions from FDA labels and peer-reviewed PubMed literature.

Where SUMMIT comes up on this site

On GLP Watchdog, SUMMIT comes up in 1 research article.

Other terms under trial

• SURMOUNT-5
• SURMOUNT-2
• SURMOUNT-3
• SURPASS-2
• SUSTAIN-6
• REWIND
• PIONEER 6
• EXSCEL
• ELIXA
• AMPLITUDE-O
• HARMONY OUTCOMES
• SCALE Diabetes
• STEP 2
• SCALE Maintenance

Where the evidence lives

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