SCALE Maintenance

What is SCALE Maintenance?

Liraglutide 3.0 mg for holding weight loss after a low-calorie-diet run-in (Wadden et al., Int J Obes 2013): it preserved −6.2% of the run-in loss at 56 weeks against −0.2% on placebo.

It made the maintenance case for a daily injectable, and was an early sign of what STEP-4 later made unambiguous.

Related reading: SCALE Maintenance: Holding On to a Loss

GLP Watchdog writes these definitions from FDA labels and peer-reviewed PubMed literature.

Where SCALE Maintenance comes up on this site

Other terms under trial

• SURMOUNT-5
• SURMOUNT-2
• SURMOUNT-3
• SURPASS-2
• SUSTAIN-6
• REWIND
• PIONEER 6
• STEP-HFpEF
• EXSCEL
• ELIXA
• AMPLITUDE-O
• HARMONY OUTCOMES
• SCALE Diabetes
• STEP 2
• SUMMIT

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