Major trials

STEP-TEENS

The Phase 3 trials that won approval, and the outcome studies that came afterward on cardiovascular, kidney and sleep-apnea endpoints.

What is STEP-TEENS?

Semaglutide 2.4 mg in adolescents aged 12–17 with obesity (Weghuber et al., NEJM 2022).

Mean weight reduction 16.7% against 0.6% on placebo. ⚠ Pediatric trials do not measure facial appearance, so anyone citing this trial alongside “Ozempic face” claims is welding two unrelated things together.

GLP Watchdog writes these definitions from FDA labels and peer-reviewed PubMed literature.

Where STEP-TEENS comes up on this site

On GLP Watchdog, STEP-TEENS comes up in 1 tool.

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Other terms under Major trials

Where the evidence lives