Major trials

ATTAIN-1

The Phase 3 trials that won approval, and the outcome studies that came afterward on cardiovascular, kidney and sleep-apnea endpoints.

What is ATTAIN-1?

Orforglipron's phase 3 in weight management, run in adults who had obesity but not diabetes: 72 weeks, N=3,127, across ten countries (NCT05869903).

On the efficacy estimand the 17.2 mg arm lost 12.4% of body weight where placebo lost 0.9%.

Foundayo drug overview →

GLP Watchdog writes these definitions from FDA labels and peer-reviewed PubMed literature.

Where ATTAIN-1 comes up on this site

On GLP Watchdog, ATTAIN-1 comes up in 4 tools.

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Where the evidence lives