GLP Watchdog

Direct Meds vs Sesame Care

Direct Meds has an open FDA warning letter dated September 9, 2025. Sesame Care has none. No price lines up like for like: Direct Meds and Sesame Care publish prices for different products.

To see where both sit among the other sellers, read our best weight-loss injection providers board.

By Ruth Calder · Enforcement Editor
Editorially reviewed. Not medical advice · How we verify contentLast reviewed

The record

Direct Meds / Sesame Care

Direct Meds logo

Direct Meds

7.1/10

Sesame Care logo

Sesame Care

8.1/10

FDA warning letters
None on record
Pharmacy
None named in our record
None named in our record
Lowest standing price
$249/moCompounded oral semaglutide
$149/moBrand-name semaglutide pill, medication only, care fee extra
States
48 states and DC
No state list published
Checked
Prices captured Record checked October 2026
Prices captured Record checked October 2026
Visit Direct Meds
Visit Sesame Care

Both Direct Meds and Sesame Care are affiliate partners: we are paid if you sign up through our links. Neither is featured. Scores are computed the same way for both (Direct Meds 7.1, Sesame Care 8.1). How we are paid

What the record shows

  1. 01

    Direct Meds has an open FDA warning letter dated September 9, 2025. Sesame Care has none.

  2. 02

    Neither names the pharmacy that compounds its medication.

  3. 03

    No price lines up like for like: Direct Meds and Sesame Care publish prices for different products.

  4. 04

    Only Direct Meds lists a price for compounded semaglutide injection, compounded tirzepatide injection and compounded oral semaglutide. Only Sesame Care lists a price for brand-name semaglutide pen, brand-name tirzepatide pen and brand-name semaglutide pill.

  5. 05

    Direct Meds lists 48 states and DC. Sesame Care publishes no state list.

  6. 06

    Direct Meds holds you to a 90-day supply shipped at once, remaining months billed every 30 days; Sesame Care states you can cancel at any time.

Prices and terms, product by product

A price is set against the other side only for the same product, and only when both are standing monthly or 4-week rates. Those pairs are compared by yearly cost.

Direct Meds

Sesame Care

Compounded semaglutide injection

$297/mo

$3,564 a year

Not sold or not priced
Compounded tirzepatide injection

$399/mo

$4,788 a year

Not sold or not priced
Brand-name semaglutide pen
Not sold or not priced

$349/mo

medication only, care fee extra; not compared

Brand-name tirzepatide pen
Not sold or not priced

$299/mo

medication only, care fee extra; not compared

Compounded oral semaglutide

$249/mo

$2,988 a year

Not sold or not priced
Compounded oral tirzepatide

$299/mo

$3,588 a year

Not sold or not priced
Brand-name semaglutide pill
Not sold or not priced

$149/mo

medication only, care fee extra; not compared

Foundayo (orforglipron) pill
Not sold or not priced

$149/mo

medication only, care fee extra; not compared

Price includes
Medication, clinician visits, shipping
Not stated
Cancel any time
No
Yes, stated
Minimum term
90-day supply shipped at once, remaining months billed every 30 days
None
Refunds
No refunds for medication already received; $35 disposal fee on returns
Full refund only if you cancel at least 3 hours before the first visit; nothing back once that visit happens
Early-exit fee
Not stated
None stated

Read off each seller’s own pages. Direct Meds: October 17, 2026. Sesame Care: October 30, 2026. Every plan and dose we hold is on the full review.

The case for each

The case for Direct Meds

7.1/10
  • Sells compounded semaglutide injection and compounded tirzepatide injection, which Sesame Care does not price
  • Open FDA warning letter, September 9, 2025
  • Names no compounding pharmacy
  • Minimum commitment before you can cancel
Visit Direct Meds

The case for Sesame Care

8.1/10
  • No FDA warning letter on record
  • Sells brand-name semaglutide pen and brand-name tirzepatide pen, which Direct Meds does not price
  • States you can cancel at any time
  • Names no compounding pharmacy
  • Publishes no state list
  • Lowest price covers the medication only, with a separate care fee on top
Visit Sesame Care

Scores

Direct Meds 7.1 · Sesame Care 8.1 out of 10. Six weighted parts.

Value25%

4.2A
vs
B
10.0

Effectiveness25%

10.0A
vs
B
10.0

User Experience15%

8.0A
vs
B
7.5

Trust & Safety15%

4.5A
vs
B
6.5

Accessibility10%

9.7A
vs
B
5.0

Support10%

7.0A
vs
B
5.0

The score is the same formula for every seller. Payment does not enter it. Method

Direct Meds vs Sesame Care: questions

Direct Meds has an open FDA warning letter dated September 9, 2025. Sesame Care has none. Letters are matched to a seller by company, domain and address, never by a similar name.
Neither names the pharmacy that compounds its medication.
No price lines up like for like: Direct Meds and Sesame Care publish prices for different products. We only set two prices against each other when they are for the same product and both are standing month-to-month or 4-week rates.
Direct Meds has a minimum term (90-day supply shipped at once, remaining months billed every 30 days). Sesame Care states you can cancel at any time; refunds: full refund only if you cancel at least 3 hours before the first visit; nothing back once that visit happens.
Both Direct Meds and Sesame Care are affiliate partners: we are paid if you sign up through our links. Neither is featured. Scores are computed the same way for both (Direct Meds 7.1, Sesame Care 8.1).

Other sellers we are paid by

Affiliate partners outside this pair. Each has its own record and review, scored the same way.

Sellers closest to these two

Matched on molecule, form and price. Every pair we list · The register

Brand names on this page are registered marks. Novo Nordisk holds Wegovy®, Ozempic® and Rybelsus®; Eli Lilly holds Zepbound®, Mounjaro® and Foundayo®. Neither company has any tie to GLP Watchdog. Trademarks