Direct Meds vs Fridays
Direct Meds and Fridays both sell semaglutide and tirzepatide; this is how their prices, coverage and records differ.
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Fridays
Best for: coaching bundled into the price rather than sold separately
Visit Fridays →If you are choosing between Direct Meds and Fridays, price alone will not settle it. Both prescribe semaglutide and tirzepatide, so moving from one to the other would not change your drug. Direct Meds leads our six-part score, 6.4 to 5.5. One of the two has an FDA warning letter on record, covered below.
Direct Meds vs Fridays price
Direct Meds and Fridays start at the same figure, $249 a month, so the entry price does not separate them. Look at what each price covers and at the per-drug prices below.
Drug by drug: Semaglutide costs the same at both, $249 a month; tirzepatide is cheaper at Direct Meds ($299 a month vs $359 a month).
Medications and formats
Both sell semaglutide and tirzepatide.
On format, Direct Meds prices compounded injections, while Fridays prices compounded injections and brand-name pens.
If you want the FDA-approved brand rather than a compounded version, Fridays is the only one of the two with a brand-name price.
Where each one treats patients
Neither Direct Meds nor Fridays publishes the states it serves, so enter your state at the very start of each sign-up.
Pricing
Direct Meds
'As low as $249' per month, on a 90-day supply billed monthly; some doses run as low as $237/mo.
'As low as $297' per month ($9.58 a day), an 84-day three-pack billed monthly.
'As low as $299' per month ($9.65 a day) on a 90-day supply billed monthly. Down from $399 earlier.
'As low as $399' per month ($12.87 a day).
Fridays
What each price covers
Both prices cover the clinician visit and the medication itself.
Direct Meds' price also covers shipping, which Fridays does not claim.
Fridays' price also covers coaching, which Direct Meds does not claim.
Direct Meds is silent on lab work and coaching.
Fridays is silent on shipping and lab work.
Direct Meds
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
Fridays
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
Not stated
Lab work
Not stated
Coaching
In the price
Where each one scores higher
Overall, Direct Meds scores 6.4 and Fridays 5.5 out of 10.
Direct Meds is stronger on value (3.7 vs 2.8) and user experience (8.0 vs 3.0).
Fridays is stronger on trust & safety (4.0 vs 3.5).
Effectiveness, accessibility and support are within half a point.
Direct Meds
6.4/10
Fridays
5.5/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
FDA warning letters
The FDA sent Direct Meds a warning letter dated September 9, 2025 (letter 716822), and it is still open.
Fridays has no FDA warning letter on record with us.
Features & Coverage
| Feature | Direct Meds | Fridays |
|---|---|---|
| Starting Price | $249/mo | $249/mo |
| Features | ✓5 features | 2 features |
| States Available | Not disclosed | Not disclosed |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | ✓ Yes |
| FSA/HSA Accepted | — | — |
| FDA Warning Letters | 1 letter | ✓None |
About Direct Meds
The FDA sent Direct Meds a warning letter in September 2025 over misleading marketing, and customers have reported a documented pattern of unexpected 3-month commitment charges. We list the company with both disclosed in full; read the warnings and the cons first. Its products are compounded semaglutide and tirzepatide, sold from Utah in injection and sublingual form.
Read our full Direct Meds review →About Fridays
Fridays is a telehealth weight loss seller running compounded GLP-1 programs.
Read our full Fridays review →Pros & Cons
Direct Meds
What we like
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- The monthly price includes the medication, clinician visits and shipping
Watch-outs
- Semaglutide costs $249 a month, 35% above the $184 median for compounded semaglutide across the sellers we compare
- Tirzepatide costs $299 a month, 20% above the $250 median for compounded tirzepatide across the sellers we compare
- Confirm it serves your state before you start the intake
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- The FDA has issued Direct Meds a warning letter. Read what it alleges: a letter flags a problem but does not by itself rule a seller out
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Fridays
What we like
- The monthly price includes the medication, clinician visits and coaching
- We found no FDA warning letters issued to Fridays
Watch-outs
- Semaglutide costs $249 a month, 35% above the $184 median for compounded semaglutide across the sellers we compare
- Tirzepatide costs $359 a month, 44% above the $250 median for compounded tirzepatide across the sellers we compare
- You only see a price after finishing the medical intake, so you cannot compare costs before sharing health information
- Confirm it serves your state before you start the intake
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Our Verdict
Direct Meds wins this one, 6.4 to 5.5, above all for compounded semaglutide at $249/month. Fridays fits better if coaching bundled into the price rather than sold separately is your priority.
Choose Direct Meds if…
You want compounded semaglutide at $249/month and an opening price near $249 a month.
Choose Fridays if…
You want coaching bundled into the price rather than sold separately and an opening price near $249 a month.
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Wellorithm
Compounded semaglutide at $247/month
From $247/mo
Get started →Willow
Seeing what it charges before you answer any medical questions
From $299/mo
Get started →Sesame Care
Oral orforglipron alongside the injectables
From $59/mo
Get started →Direct Meds vs Fridays: FAQ
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