Best PT-141 Providers in 2026: Ranked and Reviewed
Low sexual desire is the indication for PT-141 (bremelanotide). The mechanism is what separates it from the ED medications sold beside it: the central melanocortin pathway rather than blood flow. A prescription is required. A licensed clinician stands behind each provider below, and each is scored on our standard dimensions.
Lowest verified price: $99/mo61 providers compared
New to PT-141? Read our full PT-141 guide — evidence, dosing, safety and side effects.
Some of the links on this page earn us money. If you sign up with a provider after following one, that provider may pay GLP Watchdog a commission. Learn more
61 PT-141 providers compared · independently scored against our six-factor methodology.
Compare the top providers at a glance
Every row carries a logo, our editorial rating, price, the medications prescribed, and where the seller ships. Scan down a column and the list shortens fast.
- ★ Editor's Pick
people who want posted, dose-by-dose compounded tirzepatide prices and a full refund if not approved
From /mo$199.99Coverage50 statesMedicationsGHK-CuGlutathioneNAD+PT-141Sermorelin - Best Budget
people who want posted prices for compounded semaglutide or tirzepatide as a shot or a sublingual tablet
From /mo$99Coverage50 statesMedicationsGlutathioneNAD+PT-141Sermorelin starting below a standard dose, with microdose tiers
From /moCheck pricingCoverageCheck intakeMedicationsCJC-1295 / IpamorelinGHK-CuIpamorelinNAD+PT-141Sermorelin
Show 5 moreShow fewer
compounded semaglutide from $99/month, by injection or under the tongue
From /moCheck pricingCoverageCheck intakeMedicationsGonadorelinNAD+PT-141Sermorelinan oral route if you will not self-inject
From /moCheck pricingCoverage49 statesMedicationsGlutathioneNAD+PT-141Sermorelinbuyers who want compounded GLP-1 and growth-hormone peptides from one catalog
From /moCheck pricingCoverageCheck intakeMedicationsNAD+PT-141SermorelinTesamorelin- Best Care Team
people who want posted plan prices for compounded or microdosed GLP-1s with a wellness coach
From /mo$189CoverageCheck intakeMedicationsGlutathioneNAD+PT-141Sermorelin - Nationwide Coverage
people who want a posted one-month price for compounded semaglutide or tirzepatide with shipping included
From /mo$375Coverage50 statesMedicationsNAD+PT-141Sermorelin
| Provider | Rating | From /mo | Medications | Coverage | |
|---|---|---|---|---|---|
★ Editor's Pick people who want posted, dose-by-dose compounded tirzepatide prices and a full refund if not approved | $199.99 | GHK-CuGlutathioneNAD+PT-141Sermorelin | 50 states | Visit → | |
Best Budget people who want posted prices for compounded semaglutide or tirzepatide as a shot or a sublingual tablet | $99 | GlutathioneNAD+PT-141Sermorelin | 50 states | Visit → | |
 starting below a standard dose, with microdose tiers | Check pricing | CJC-1295 / IpamorelinGHK-CuIpamorelinNAD+PT-141Sermorelin | Check intake | Visit → | |
 compounded semaglutide from $99/month, by injection or under the tongue | Check pricing | GonadorelinNAD+PT-141Sermorelin | Check intake | Visit → | |
 an oral route if you will not self-inject | Check pricing | GlutathioneNAD+PT-141Sermorelin | 49 states | Visit → | |
 buyers who want compounded GLP-1 and growth-hormone peptides from one catalog | Check pricing | NAD+PT-141SermorelinTesamorelin | Check intake | Visit → | |
Best Care Team people who want posted plan prices for compounded or microdosed GLP-1s with a wellness coach | $189 | GlutathioneNAD+PT-141Sermorelin | Check intake | Visit → | |
Nationwide Coverage people who want a posted one-month price for compounded semaglutide or tirzepatide with shipping included | $375 | NAD+PT-141Sermorelin | 50 states | Visit → |
All 61 providers on this board, in the order this board shows them
The comparison above shows the first 8. This is the full list the filter counts refer to, in the order this board shows them; each name opens that provider’s review.
- Optimize HP
- Riovie
- Telos Rx
- Try Ageless
- YOURx Health
- Believe Health
- Idun Rx
- LongevityFix MD
- PlexusDx
- Pepti
- Madison Meds
- RxION Health
- WePeptideRx
- CAPO Health
- Forever Health Rx
- EverPrime
- AgelessRx
- Longevixx
- Mirabel Meds
- Rixa Health
- Next Vial
- BioPivot
- Heva Health
- HealifyNow
- Lifeforce
- Lumora
- Mankind Health
- Nu Image Medical
- TRT Kingdom
- OneTwenty
- Kin Meds
- TeleZen MD
- TomorrowsRX
- YourHealthRx
- Immortals
- Guppy Meds
- iThriveMD
- OmniRx Health
- Bodybuilding Health+
- RxPepsDirect
- Onyx Weight Loss
- Harmony Wellness Clinic
- HealthOn
- Drakewell Health
- Rebody Health
- LaSara Medical Group
- Invigor Medical
- Morph Health & Wellness
- Invite Wellness
- SynergenX Health
- HealthClinic MD
- Viking Alternative Medicine
- Limitless Male
- Ecka Health
- Gameday Men's Health
- Prestige Health Rx
- Valhalla Vitality
- HexisMD
- REGENX Health
- Tactus Health
- LiveNow Longevity
A seller that shows no price until after the medical intake loses points on User Experience and Trust & Safety, and its review says so. How we score →
Detailed Reviews
About the prices below: every dollar figure inside these provider summaries belongs to that clinic’s GLP‑1 weight-loss program. None is a PT-141 price. For PT-141 itself, read the figure next to each clinic in the comparison table above, taken from the clinic’s own product page. A reading of “Check pricing” means the clinic does prescribe PT-141 and publishes nothing for it, so you are quoted after your consultation.
Optimize HP
Best for: people who want posted, dose-by-dose compounded tirzepatide prices and a full refund if not approved
Optimize HP is a telehealth brand, run by a Texas management company, that sells a lab-based wellness membership and, separately, single prescription therapies, including compounded tirzepatide with B12. Tirzepatide is priced by dose on the page, from $99 every 4 weeks on a 3-month plan at up to 5 mg a week to $199 at 15 mg, with shipping, supplies and the service fee included. Month-to-month costs half again as much. If a provider does not approve, you are refunded in full or never charged.
Score Breakdown
Pros
- ✓Tirzepatide costs $99 a month, 63% below the $269 median for compounded tirzepatide across the sellers we compare
- ✓Shows its price before the medical questionnaire, so you can compare it without handing over health information
- ✓The monthly price includes the medication and shipping
- ✓Serves all 50 states
- ✓We found no FDA warning letters issued to Optimize HP
Cons
- ✗Ask which pharmacy fills the prescription before you pay, so you can check its license
- ✗Its tirzepatide is compounded rather than FDA-approved, so it has not been reviewed by the agency for safety, effectiveness or manufacturing quality
Riovie
Best for: people who want posted prices for compounded semaglutide or tirzepatide as a shot or a sublingual tablet
Riovie is an online clinic that prescribes compounded semaglutide and tirzepatide as a weekly injection or a daily under-the-tongue tablet, alongside menopause hormone therapy and longevity treatments such as sermorelin, NAD+ and glutathione. It names its medical group and its compounding pharmacy and publishes its state list. Injectable semaglutide is $149 for one month or $345 for a 3-month plan; tirzepatide is $209 or $585.
Score Breakdown
Pros
- ✓Semaglutide costs $149 a month, 25% below the $199 median for compounded semaglutide across the sellers we compare
- ✓Tirzepatide costs $209 a month, 22% below the $269 median for compounded tirzepatide across the sellers we compare
- ✓Shows its price before the medical questionnaire, so you can compare it without handing over health information
- ✓The monthly price includes the medication, clinician visits and shipping
- ✓Serves all 50 states
- ✓Names VialsRX as the pharmacy that fills its prescriptions, which most sellers do not
- ✓We found no FDA warning letters issued to Riovie
Cons
- ✗Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Telos Rx
Best for: starting below a standard dose, with microdose tiers
Score breakdown, pros and cons
Telos Rx, run by Superior Health Solutions LLC, sells compounded semaglutide from $99 a month, tirzepatide from $139 and microdosed tirzepatide from $116, plus under-the-tongue semaglutide or tirzepatide from $9 a day. Those are the lowest plan-length prices, and the rate for each plan length is not published. Quit a prepaid plan before its term ends and the discount is clawed back. NAD+, sermorelin and PT-141 are also sold.
Score Breakdown
Pros
- ✓Semaglutide costs $99 a month, 50% below the $199 median for compounded semaglutide across the sellers we compare
- ✓Tirzepatide costs $139 a month, 48% below the $269 median for compounded tirzepatide across the sellers we compare
- ✓Shows its price before the medical questionnaire, so you can compare it without handing over health information
- ✓The monthly price includes the medication, clinician visits and shipping
- ✓We found no FDA warning letters issued to Telos Rx
Cons
- ✗Confirm it serves your state before you start the intake
- ✗Ask which pharmacy fills the prescription before you pay, so you can check its license
- ✗Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Try Ageless
Best for: compounded semaglutide from $99/month, by injection or under the tongue
Score breakdown, pros and cons
Try Ageless sells compounded semaglutide and tirzepatide in four formats: weekly injection, sublingual drops, troche and a dissolving tablet. Semaglutide injection starts at $99 a month and rises with the dose to $229; a $50 coupon applies to the first order. The platform frames itself around longevity and metabolic health and holds LegitScript certification.
Score Breakdown
Pros
- ✓Semaglutide costs $99 a month, 50% below the $199 median for compounded semaglutide across the sellers we compare
- ✓Tirzepatide costs $169 a month, 37% below the $269 median for compounded tirzepatide across the sellers we compare
- ✓Shows its price before the medical questionnaire, so you can compare it without handing over health information
- ✓The monthly price includes the medication and shipping
- ✓Names Pharmacy Hub as the pharmacy that fills its prescriptions, which most sellers do not
- ✓We found no FDA warning letters issued to Try Ageless
Cons
- ✗Confirm it serves your state before you start the intake
- ✗Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
YOURx Health
Best for: an oral route if you will not self-inject
Score breakdown, pros and cons
YOURx Health, operated by YOURx Health LLC of Beaumont, TX, sells compounded semaglutide and tirzepatide with B12 as weekly injections or rapid-dissolve tablets. Injections are $159 a month for semaglutide and $179 for tirzepatide; tablets are $139 and $159. Care runs through MD Integrations with a physician video visit, and it is self-pay only. Its FAQ says it serves every state but Mississippi.
Score Breakdown
Pros
- ✓Semaglutide costs $139 a month, 30% below the $199 median for compounded semaglutide across the sellers we compare
- ✓Tirzepatide costs $159 a month, 41% below the $269 median for compounded tirzepatide across the sellers we compare
- ✓Shows its price before the medical questionnaire, so you can compare it without handing over health information
- ✓The monthly price includes the medication
- ✓Serves 49 states
- ✓We found no FDA warning letters issued to YOURx Health
- ✓A live video visit with a clinician is required before a prescription, which is slower than a form and is the more careful intake
Cons
- ✗Ask which pharmacy fills the prescription before you pay, so you can check its license
- ✗Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Buying PT-141: approved product, or a compound
Bremelanotide, sold as PT-141, is the only molecule in this category holding a genuine FDA approval. That approval covers Vyleesi, in premenopausal women with hypoactive sexual desire disorder. What telehealth clinics mostly dispense is a compounded version, frequently to men, which uses an approved molecule off label.
What to check
- Vyleesi, or a compounded vial. An approved autoinjector and a compounded vial differ in price, in labeling, and in what has been approved about them. Which one a clinic dispenses is a single sentence it either publishes or leaves out.
- Dosed before activity, not daily. The dose goes in ahead of anticipated activity. No daily schedule exists for this molecule, so a clinic selling one has the model wrong.
- Blood pressure asked about. A transient rise in blood pressure, and a drop in heart rate, follow the dose. Uncontrolled hypertension and known cardiovascular disease are contraindications on that basis. An intake either asks about them or omits the main safety check in this category.
Red flags
- Vials sold with no prescriber involved. A vial marked 'not for human consumption' and sold 'for research use only' sits outside the drug approval system, where identity, purity and sterility are nobody's stated responsibility. In the US, every peptide on this page needs a prescription. Where no licensed clinician writes one, the product is not the one described here.
- The 503A or 503B pharmacy is never named. No finished product for these peptides carries FDA approval, which leaves compounding as the only lawful route to a dose. Plenty of clinics name the pharmacy behind the vial. Where a clinic does not, the supply chain ends at its own claim.
- 'FDA-approved' attached to a compounded peptide. Compounding does not bring FDA approval with it, and a seller saying otherwise has committed a marketing violation rather than a slip of wording. A few of these molecules did hold an approval once, under a discontinued brand and for a separate indication. That history says nothing about the compounded vial on sale now.
- Results promised with no trial behind them. For most molecules in this category the evidence is mechanistic or early phase; randomized outcome trials are rare. A clinic promising a defined outcome for fat loss, for muscle, or for anti-aging has moved past what the literature carries. Our evidence review for each molecule sets out what exists.
- IGF-1 never drawn on a hormone-axis peptide. Raising IGF-1 is what a growth-hormone secretagogue is for, and it is also the number that shows when a dose has gone too far. A clinic measuring it at neither baseline nor follow-up has no way to tell those two states apart.
Every seller listed above is scored on these criteria under our six-dimension methodology, with prices re-checked against the seller’s own live site.
How we rank, and what counts as “legit”
Scoring for every provider on this page runs against our published six-factor rubric[1]: value, effectiveness, user experience, trust & safety, accessibility and support.
Each of Wegovy, Zepbound, Ozempic and Mounjaro holds its own separate FDA approval under its own NDA number[4][5]. Published Phase 3 efficacy for semaglutide at 2.4 mg (~14.9% mean weight loss across 68 weeks) comes from STEP 1[6]; those for tirzepatide (~20.9% at the 15 mg dose over 72 weeks) come from SURMOUNT-1[7]. In 2025 the SURMOUNT-5 head-to-head set the two against each other[8].
How much of an anti-obesity medication is covered varies widely between state Medicaid programs and between commercial plans[9][10]. Under IRS Publication 502, compounded GLP-1s and brand-name ones alike are generally FSA/HSA eligible where a prescription exists[11].
Frequently Asked Questions
Glossary
The words sellers use, defined. Tap any term.
- 503A pharmacy · Pharmacy and drug forms
- 503A vs 503B (pharmacy compounding) · Pharmacy and drug forms
- 503B outsourcing facility · Pharmacy and drug forms
Sources & methodology — as of November 2026
- 1.GLP Watchdog — GLP-1 Pricing Index 2026 (our independent dataset)— GLP Watchdog.
- 2.FDA — Compounding and the 503A Pharmacy Framework— U.S. Food & Drug Administration.
- 3.FDA — Drug Shortages Database (current shortage listings)— U.S. Food & Drug Administration.
- 4.FDA — Wegovy (semaglutide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
- 5.FDA — Zepbound (tirzepatide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
- 6.STEP 1 Trial — Once-Weekly Semaglutide in Adults with Overweight or Obesity (Wilding JPH et al.)— New England Journal of Medicine.PMID: 33567185.
- 7.SURMOUNT-1 Trial — Tirzepatide Once Weekly for the Treatment of Obesity (Jastreboff AM et al.)— New England Journal of Medicine.PMID: 35658024.
- 8.SURMOUNT-5 Trial — Tirzepatide vs. Semaglutide Head-to-Head in Obesity (Aronne LJ et al.)— New England Journal of Medicine.PMID: 40353578.
- 9.KFF — Medicaid coverage research (anti-obesity & GLP-1 drug policy)— Kaiser Family Foundation.
- 10.CMS — Medicaid prescription drug coverage policy (state-by-state)— Centers for Medicare & Medicaid Services.
- 11.IRS Publication 502 — Medical and Dental Expenses (HSA/FSA eligibility)— Internal Revenue Service.