LifeMD vs SkinnyRx
LifeMD and SkinnyRx both sell semaglutide and tirzepatide; this is how their prices, coverage and records differ.
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LifeMD
Best for: bloodwork inside the monthly price rather than billed on top
Visit LifeMD →
If you are choosing between LifeMD and SkinnyRx, price alone will not settle it. Both prescribe semaglutide and tirzepatide, so moving from one to the other would not change your drug. LifeMD leads our six-part score, 7.9 to 5.9. One of the two has an FDA warning letter on record, covered below.
LifeMD vs SkinnyRx price
LifeMD and SkinnyRx start at within a dollar of each other ($149 and $149.25 a month), so the entry price does not separate them. Look at what each price covers and at the per-drug prices below.
Drug by drug: Semaglutide costs the same at both, $149 a month; tirzepatide is cheaper at SkinnyRx ($224.25 a month vs $349 a month).
Medications and formats
Both sell semaglutide and tirzepatide.
On format, LifeMD prices brand-name pens, while SkinnyRx prices compounded injections and an oral option.
If you want the FDA-approved brand rather than a compounded version, LifeMD is the only one of the two with a brand-name price.
Where each one treats patients
LifeMD lists 50 states, and SkinnyRx does not publish where it ships.
Pricing
LifeMD
First month $75, then $149/mo. Brand medication billed separately, or $0-$25/mo copay with commercial insurance.
Medication only; plus the $149/mo program fee.
Medication only (starting); plus the program fee. As low as $0-$25/mo with insurance.
Medication only; plus the $149/mo program fee.
SkinnyRx
'As low as $149.25/mo*' — plan-length/promo dependent (matches the sitewide '25% lower prices' promo, $199 x 0.75); standard single-month rate not published pre-intake. Microdose available; free overnight shipping.
'As low as $199/mo*' on /products/semaglutide-oral; once-daily.
'As low as $249/mo*' on /products/semaglutide-tablets.
'As low as $224.25/mo*' and 'Starting at $224.25/mo with free overnight shipping'; microdose available; once-weekly.
'As low as $224.25/mo*' on /products/tirzepatide-tablets; once-daily.
'$1,400/mo*' — '*Price shown applies to Monthly plan paid upfront or with buy now, pay later programs.' 'No membership fees. Same price at every dose.'
'$1,400/mo*' on /products/wegovy-injectable. Wegovy PILL is listed 'Unavailable' ('available via SkinnyRx Membership', fee not published).
'$1,400/mo*' on /products/mounjaro.
'$1,400/mo*' on /products/zepbound. Foundayo (orforglipron) pill also listed but 'Unavailable' — price not published.
What each price covers
Both prices cover the clinician visit.
LifeMD's price also covers lab work and coaching, which SkinnyRx does not claim.
SkinnyRx's price also covers the medication itself and shipping, which LifeMD does not claim.
LifeMD is silent on shipping.
SkinnyRx is silent on lab work and coaching.
That matters most for the drug: unless LifeMD confirms otherwise, budget for medication on top of its listed price.
LifeMD
Covered by the monthly price
Medication
Charged on top
Clinician visits
In the price
Shipping
Not stated
Lab work
In the price
Coaching
In the price
SkinnyRx
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
Where each one scores higher
Overall, LifeMD scores 7.9 and SkinnyRx 5.9 out of 10.
LifeMD is stronger on value (10.0 vs 6.5), trust & safety (6.0 vs 1.0) and accessibility (10.0 vs 5.0).
SkinnyRx is stronger on support (7.0 vs 5.5).
Effectiveness and user experience are within half a point.
LifeMD
7.9/10
SkinnyRx
5.9/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
FDA warning letters
The FDA sent SkinnyRx a warning letter dated February 20, 2026 (letter 717989), and it is still open.
LifeMD has no FDA warning letter on record with us.
Features & Coverage
| Feature | LifeMD | SkinnyRx |
|---|---|---|
| Starting Price | ✓$149/mo | $149.25/mo |
| Features | 0 features | ✓3 features |
| States Available | 50 | Not disclosed |
| Compounded | — | ✓ Yes |
| Brand Name | ✓ Yes | — |
| FSA/HSA Accepted | — | — |
| FDA Warning Letters | ✓None | 1 letter |
About LifeMD
LifeMD is a publicly traded telehealth seller. It carries brand-name GLP-1 medications only.
Read our full LifeMD review →About SkinnyRx
SkinnyRx sells compounded semaglutide and tirzepatide as injectables, with a microdosing option, prescribed by licensed US clinicians. The consult and free overnight shipping are bundled into a single monthly cash price.
Read our full SkinnyRx review →Pros & Cons
LifeMD
What we like
- Semaglutide costs $149 a month, 85% below the $990 median for brand-name semaglutide across the sellers we compare
- Tirzepatide costs $349 a month, 72% below the $1249 median for brand-name tirzepatide across the sellers we compare
- The monthly price includes clinician visits, lab work and coaching
- Serves all 50 states
- We found no FDA warning letters issued to LifeMD
Watch-outs
- You only see a price after finishing the medical intake, so you cannot compare costs before sharing health information
- Not included in the monthly price: medication
- Ask which pharmacy fills the prescription before you pay, so you can check its license
SkinnyRx
What we like
- Semaglutide costs $149.25 a month, 19% below the $184 median for compounded semaglutide across the sellers we compare
- Tirzepatide costs $224.25 a month, 10% below the $250 median for compounded tirzepatide across the sellers we compare
- The monthly price includes the medication, clinician visits and shipping
- Offers both oral and injectable options, so the format is your choice
Watch-outs
- You only see a price after finishing the medical intake, so you cannot compare costs before sharing health information
- Confirm it serves your state before you start the intake
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- The FDA has issued SkinnyRx a warning letter. Read what it alleges: a letter flags a problem but does not by itself rule a seller out
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Our Verdict
SkinnyRx is where we would start, above all for starting below a standard dose, with microdose tiers. LifeMD fits better if bloodwork inside the monthly price rather than billed on top is your priority.
Choose LifeMD if…
You want bloodwork inside the monthly price rather than billed on top and an opening price near $149 a month.
Choose SkinnyRx if…
You want starting below a standard dose, with microdose tiers and an opening price near $149.25 a month.
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Collective
Flat any-dose pricing, if you can absorb a $199 annual membership on top
From $59/mo
Get started →Found
Tirzepatide at $169/month, 37% below the typical price
From $149/mo
Get started →Breeze Meds
Knowing which pharmacy fills the vial: it names Belmar Pharmacy
From $199/mo
Get started →LifeMD vs SkinnyRx: FAQ
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Novo Nordisk A/S owns the Wegovy®, Ozempic® and Rybelsus® marks; Eli Lilly and Company owns Mounjaro® and Zepbound®. Every other product name and mark on this page belongs to whoever owns it. No pharmaceutical manufacturer is affiliated with GLP Watchdog. See trademark disclaimer.