LifeMD vs TrimRx
LifeMD costs $30 less a month, and both sell semaglutide and tirzepatide.
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LifeMD
Best for: bloodwork inside the monthly price rather than billed on top
Visit LifeMD →
If you are choosing between LifeMD and TrimRx, the first difference is cost: LifeMD is $30 a month cheaper at the entry price. Both prescribe semaglutide and tirzepatide, so moving from one to the other would not change your drug. LifeMD leads our six-part score, 7.9 to 7.2.
LifeMD vs TrimRx price
LifeMD is the cheaper way in: $149 a month against $179 a month at TrimRx. That is $30 less each month (17% lower), or about $360 over a year of treatment.
Drug by drug: Semaglutide is cheaper at LifeMD ($149 a month vs $179 a month); tirzepatide is cheaper at TrimRx ($259 a month vs $349 a month).
Medications and formats
Both sell semaglutide and tirzepatide.
On format, LifeMD prices brand-name pens, while TrimRx prices compounded injections and brand-name pens.
Where each one treats patients
LifeMD lists 50 states, and TrimRx does not publish where it ships.
Pricing
LifeMD
First month $75, then $149/mo. Brand medication billed separately, or $0-$25/mo copay with commercial insurance.
Medication only; plus the $149/mo program fee.
Medication only (starting); plus the program fee. As low as $0-$25/mo with insurance.
Medication only; plus the $149/mo program fee.
TrimRx
GLP-1 starts at $179. The homepage shows a $299.00 list price struck through to $179.00 for the first month, and an email sign-up offer promises '$120 OFF' your first order, for a first month as low as $135. Multi-month bundles (formerly $209/$191/$174) are no longer published; plan prices appear only after the intake questionnaire.
The GLP-1 + GIP plan, which contains tirzepatide, starts at $259, down from an earlier $279 limited offer. Multi-month bundles (formerly $316/$299/$283) are no longer published; plan prices appear only after the intake questionnaire.
'Mounjaro® Starting at $1249' homepage tile; same branded-fulfillment caveat.
'Zepbound® Starting at $1249' homepage tile; same branded-fulfillment caveat.
'Wegovy® Starting at $1579' homepage tile; same branded-fulfillment caveat.
What each price covers
Both prices cover the clinician visit.
LifeMD's price also covers lab work and coaching, which TrimRx does not claim.
TrimRx's price also covers the medication itself and shipping, which LifeMD does not claim.
LifeMD is silent on shipping.
TrimRx is silent on lab work and coaching.
That matters most for the drug: unless LifeMD confirms otherwise, budget for medication on top of its listed price.
LifeMD
Covered by the monthly price
Medication
Charged on top
Clinician visits
In the price
Shipping
Not stated
Lab work
In the price
Coaching
In the price
TrimRx
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
Where each one scores higher
Overall, LifeMD scores 7.9 and TrimRx 7.2 out of 10.
LifeMD is stronger on value (10.0 vs 5.2) and accessibility (10.0 vs 5.0).
TrimRx is stronger on user experience (8.0 vs 3.0), trust & safety (6.5 vs 6.0) and support (7.0 vs 5.5).
Effectiveness is within half a point.
LifeMD
7.9/10
TrimRx
7.2/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
FDA warning letters
Neither LifeMD nor TrimRx has an FDA warning letter on record with us.
Features & Coverage
| Feature | LifeMD | TrimRx |
|---|---|---|
| Starting Price | ✓$149/mo | $179/mo |
| Features | 0 features | ✓8 features |
| States Available | 50 | Not disclosed |
| Compounded | — | ✓ Yes |
| Brand Name | ✓ Yes | ✓ Yes |
| FSA/HSA Accepted | — | — |
| FDA Warning Letters | None | None |
About LifeMD
LifeMD is a publicly traded telehealth seller. It carries brand-name GLP-1 medications only.
Read our full LifeMD review →About TrimRx
Three things TrimRx does not publish: the pharmacy that compounds its drugs, the states it serves, and any LegitScript certification. Specifics sit behind an intake quiz. What is visible is a cash-pay program with tiered monthly pricing plus multi-month bundles, no insurance, selling compounded semaglutide and tirzepatide shipped monthly at no shipping cost. Licensed US providers prescribe after reviewing an online medical history. The pitch is dose continuity and stable pricing: "switch and keep your current dose, no price hikes". Compounded GLP-1s are not FDA-approved.
Read our full TrimRx review →Pros & Cons
LifeMD
What we like
- Semaglutide costs $149 a month, 85% below the $990 median for brand-name semaglutide across the sellers we compare
- Tirzepatide costs $349 a month, 72% below the $1249 median for brand-name tirzepatide across the sellers we compare
- The monthly price includes clinician visits, lab work and coaching
- Serves all 50 states
- We found no FDA warning letters issued to LifeMD
Watch-outs
- You only see a price after finishing the medical intake, so you cannot compare costs before sharing health information
- Not included in the monthly price: medication
- Ask which pharmacy fills the prescription before you pay, so you can check its license
TrimRx
What we like
- Semaglutide costs $179 a month, close to the $184 median for compounded semaglutide across the sellers we compare
- Tirzepatide costs $259 a month, close to the $250 median for compounded tirzepatide across the sellers we compare
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- The monthly price stays the same as your dose goes up
- The monthly price includes the medication, clinician visits and shipping
- We found no FDA warning letters issued to TrimRx
Watch-outs
- Confirm it serves your state before you start the intake
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Our Verdict
LifeMD wins this one, 7.9 to 7.2, above all for bloodwork inside the monthly price rather than billed on top. It also costs $30 less each month than TrimRx. TrimRx fits better if compounded semaglutide at $179/month is your priority.
Choose LifeMD if…
You want bloodwork inside the monthly price rather than billed on top and an opening price near $149 a month.
Choose TrimRx if…
You want compounded semaglutide at $179/month and an opening price near $179 a month.
Ready to start? GLP-1 providers we have vetted
Telehealth providers, vetted by us, prescribing GLP-1 online.
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Found
Tirzepatide at $169/month, 37% below the typical price
From $149/mo
Get started →Breeze Meds
Knowing which pharmacy fills the vial: it names Belmar Pharmacy
From $199/mo
Get started →HealthRX
Compounded semaglutide at $133/month
From $133/mo
Get started →LifeMD vs TrimRx: FAQ
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Or see the full category ranking.
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