Direct Meds vs Midi Health
Direct Meds and Midi Health sell different medications; this is what separates them.
Some of the links on this page earn us money. If you sign up with a provider after following one, that provider may pay GLP Watchdog a commission. Learn more
Midi Health
Best for: coverage in all 50 states, which most sellers will not confirm
Visit Midi Health →If you are choosing between Direct Meds and Midi Health, price alone will not settle it. Direct Meds leads our six-part score, 6.4 to 4.6. One of the two has an FDA warning letter on record, covered below.
Direct Meds vs Midi Health price
Direct Meds publishes $249 a month. Midi Health does not post a GLP-1 price we can quote, so you would only learn its cost after an intake.
Medications and formats
Direct Meds lists semaglutide and tirzepatide; Midi Health does not name its drug.
On format, Direct Meds prices compounded injections, while Midi Health posts no priced format.
Where each one treats patients
Direct Meds does not publish where it ships, and Midi Health lists 50 states.
Pricing
Direct Meds
'As low as $249' per month, on a 90-day supply billed monthly; some doses run as low as $237/mo.
'As low as $297' per month ($9.58 a day), an 84-day three-pack billed monthly.
'As low as $299' per month ($9.65 a day) on a 90-day supply billed monthly. Down from $399 earlier.
'As low as $399' per month ($12.87 a day).
Midi Health
Per-visit self-pay fee, NOT a monthly medication price; GLP-1 medication billed separately or through insurance. No compounded medication price is published on the current site.
Per-visit self-pay fee; medication not included. Under insurance you instead pay your standard copay + deductible.
What each price covers
Direct Meds' price also covers the clinician visit, the medication itself and shipping, which Midi Health does not claim.
Direct Meds is silent on lab work and coaching.
Midi Health does not say what its price includes.
That matters most for the drug: unless Midi Health confirms otherwise, budget for medication on top of its listed price.
Direct Meds
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
Midi Health
Inclusions not disclosed.
Where each one scores higher
Overall, Direct Meds scores 6.4 and Midi Health 4.6 out of 10.
Direct Meds is stronger on value (3.7 vs 3.0), effectiveness (10.0 vs 5.0), user experience (8.0 vs 2.5) and support (7.0 vs 5.0).
Midi Health is stronger on trust & safety (5.0 vs 3.5) and accessibility (10.0 vs 5.0).
Direct Meds
6.4/10
Midi Health
4.6/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
FDA warning letters
The FDA sent Direct Meds a warning letter dated September 9, 2025 (letter 716822), and it is still open.
Midi Health has no FDA warning letter on record with us.
Features & Coverage
| Feature | Direct Meds | Midi Health |
|---|---|---|
| Starting Price | $249/mo | Not published |
| Features | 5 features | 5 features |
| States Available | Not disclosed | 50 |
| Compounded | ✓ Yes | — |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warning Letters | 1 letter | ✓None |
About Direct Meds
The FDA sent Direct Meds a warning letter in September 2025 over misleading marketing, and customers have reported a documented pattern of unexpected 3-month commitment charges. We list the company with both disclosed in full; read the warnings and the cons first. Its products are compounded semaglutide and tirzepatide, sold from Utah in injection and sublingual form.
Read our full Direct Meds review →About Midi Health
Medicare, Medicaid, and Medi-Cal are all refused at Midi Health, though commercial insurance is taken. The platform covers menopause and perimenopause nationwide, in 50 states. GLP-1s are not sold here as a standalone weight-loss product; a clinician may add one at their discretion, a metabolic-health adjunct inside the menopause care framework.
Read our full Midi Health review →Pros & Cons
Direct Meds
What we like
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- The monthly price includes the medication, clinician visits and shipping
Watch-outs
- Semaglutide costs $249 a month, 35% above the $184 median for compounded semaglutide across the sellers we compare
- Tirzepatide costs $299 a month, 20% above the $250 median for compounded tirzepatide across the sellers we compare
- Confirm it serves your state before you start the intake
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- The FDA has issued Direct Meds a warning letter. Read what it alleges: a letter flags a problem but does not by itself rule a seller out
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Midi Health
What we like
- Serves all 50 states
- We found no FDA warning letters issued to Midi Health
- A live video visit with a clinician is required before a prescription, which is slower than a form and is the more careful intake
Watch-outs
- You only see a price after finishing the medical intake, so you cannot compare costs before sharing health information
- Ask which pharmacy fills the prescription before you pay, so you can check its license
Our Verdict
Direct Meds wins this one, 6.4 to 4.6, above all for compounded semaglutide at $249/month. Midi Health fits better if coverage in all 50 states, which most sellers will not confirm is your priority.
Choose Direct Meds if…
You want compounded semaglutide at $249/month and an opening price near $249 a month.
Choose Midi Health if…
You want coverage in all 50 states, which most sellers will not confirm.
Ready to start? GLP-1 providers we have vetted
Telehealth providers, vetted by us, prescribing GLP-1 online.
Vetted by our editors · no insurance required
Some of the links on this page earn us money. If you sign up with a provider after following one, that provider may pay GLP Watchdog a commission. Learn more
RNK Health
An oral route if you will not self-inject
From $197/mo
Get started →He & She MD
Starting below a standard dose, with microdose tiers
From $99/mo
Get started →Wellorithm
Compounded semaglutide at $247/month
From $247/mo
Get started →Direct Meds vs Midi Health: FAQ
Close alternatives to Direct Meds and Midi Health
- Direct Meds vs Henry Meds
- Direct Meds vs Fridays
- Direct Meds vs Luvo Health
- Direct Meds vs RxSpan MD
- Midi Health vs Embody
- Midi Health vs TrimRx
Or see the full category ranking.