Direct Meds vs Hers
Hers costs $50 less a month, and both sell semaglutide and tirzepatide.
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Hers
Best for: coverage in all 50 states, which most sellers will not confirm
Visit Hers →If you are choosing between Direct Meds and Hers, the first difference is cost: Hers is $50 a month cheaper at the entry price. Both prescribe semaglutide and tirzepatide, so moving from one to the other would not change your drug. Hers leads our six-part score, 7.0 to 6.4. One of the two has an FDA warning letter on record, covered below.
Direct Meds vs Hers price
Hers is the cheaper way in: $199 a month against $249 a month at Direct Meds. That is $50 less each month (20% lower), or about $600 over a year of treatment.
Drug by drug: Semaglutide is cheaper at Hers ($199 a month vs $249 a month); tirzepatide costs the same at both, $299 a month.
Medications and formats
Both sell semaglutide and tirzepatide.
On format, Direct Meds prices compounded injections, while Hers prices compounded injections and brand-name pens.
If you want the FDA-approved brand rather than a compounded version, Hers is the only one of the two with a brand-name price.
Where each one treats patients
Direct Meds does not publish where it ships, and Hers lists 50 states.
Pricing
Direct Meds
'As low as $249' per month, on a 90-day supply billed monthly; some doses run as low as $237/mo.
'As low as $297' per month ($9.58 a day), an 84-day three-pack billed monthly.
'As low as $299' per month ($9.65 a day) on a 90-day supply billed monthly. Down from $399 earlier.
'As low as $399' per month ($12.87 a day).
Hers
Brand Zepbound from $299/mo medication-only; requires Hers Weight Loss Membership ($149/mo)
What each price covers
Both prices cover the medication itself.
Direct Meds' price also covers the clinician visit and shipping, which Hers does not claim.
Direct Meds is silent on lab work and coaching.
Hers is silent on shipping and lab work.
Direct Meds
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
Hers
Covered by the monthly price
Medication
In the price
Clinician visits
Charged on top
Shipping
Not stated
Lab work
Not stated
Coaching
Charged on top
Where each one scores higher
Overall, Hers scores 7.0 and Direct Meds 6.4 out of 10.
Direct Meds is stronger on value (3.7 vs 3.0) and support (7.0 vs 3.0).
Hers is stronger on trust & safety (8.5 vs 3.5) and accessibility (10.0 vs 5.0).
Effectiveness and user experience are within half a point.
Direct Meds
6.4/10
Hers
7.0/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
FDA warning letters
The FDA sent Direct Meds a warning letter dated September 9, 2025 (letter 716822), and it is still open.
Hers has no FDA warning letter on record with us.
Features & Coverage
| Feature | Direct Meds | Hers |
|---|---|---|
| Starting Price | $249/mo | ✓$199/mo |
| Features | ✓5 features | 2 features |
| States Available | Not disclosed | 50 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | ✓ Yes |
| FSA/HSA Accepted | — | — |
| FDA Warning Letters | 1 letter | ✓None |
About Direct Meds
The FDA sent Direct Meds a warning letter in September 2025 over misleading marketing, and customers have reported a documented pattern of unexpected 3-month commitment charges. We list the company with both disclosed in full; read the warnings and the cons first. Its products are compounded semaglutide and tirzepatide, sold from Utah in injection and sublingual form.
Read our full Direct Meds review →About Hers
Hers is the women-focused telehealth brand from Hims and Hers. It sells compounded semaglutide on a 6-month plan.
Read our full Hers review →Pros & Cons
Direct Meds
What we like
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- The monthly price includes the medication, clinician visits and shipping
Watch-outs
- Semaglutide costs $249 a month, 35% above the $184 median for compounded semaglutide across the sellers we compare
- Tirzepatide costs $299 a month, 20% above the $250 median for compounded tirzepatide across the sellers we compare
- Confirm it serves your state before you start the intake
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- The FDA has issued Direct Meds a warning letter. Read what it alleges: a letter flags a problem but does not by itself rule a seller out
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Hers
What we like
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- The monthly price includes the medication
- Serves all 50 states
- We found no FDA warning letters issued to Hers
Watch-outs
- Not included in the monthly price: clinician visits, coaching
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- Its semaglutide is compounded rather than FDA-approved, so it has not been reviewed by the agency for safety, effectiveness or manufacturing quality
Our Verdict
Direct Meds is where we would start, above all for compounded semaglutide at $249/month. Hers undercuts it by $50 a month, so if the monthly bill is what decides it, Hers is the pick. Hers fits better if coverage in all 50 states, which most sellers will not confirm is your priority.
Choose Direct Meds if…
You want compounded semaglutide at $249/month and an opening price near $249 a month.
Choose Hers if…
You want coverage in all 50 states, which most sellers will not confirm and an opening price near $199 a month.
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Breeze Meds
Knowing which pharmacy fills the vial: it names Belmar Pharmacy
From $199/mo
Get started →HealthRX
Compounded semaglutide at $133/month
From $133/mo
Get started →RNK Health
An oral route if you will not self-inject
From $197/mo
Get started →Direct Meds vs Hers: FAQ
Close alternatives to Direct Meds and Hers
- Direct Meds vs Henry Meds
- Direct Meds vs Fridays
- Direct Meds vs Luvo Health
- Direct Meds vs RxSpan MD
- Hers vs Hims
- Hers vs Noom
Or see the full category ranking.
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