altRX vs Rylo Health
altRX and Rylo Health both sell semaglutide and tirzepatide; this is how their prices, coverage and records differ.
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Rylo Health
Best for: coverage in all 50 states, which most sellers will not confirm
Visit Rylo Health →If you are choosing between altRX and Rylo Health, price alone will not settle it. Both prescribe semaglutide and tirzepatide, so moving from one to the other would not change your drug. Rylo Health leads our six-part score, 8.2 to 7.6. One of the two has an FDA warning letter on record, covered below.
altRX vs Rylo Health price
altRX and Rylo Health start at the same figure, $149 a month, so the entry price does not separate them. Look at what each price covers and at the per-drug prices below.
Drug by drug: Semaglutide costs the same at both, $149 a month; tirzepatide costs the same at both, $249 a month.
Medications and formats
Both sell semaglutide and tirzepatide.
On format, altRX prices compounded injections and brand-name pens, while Rylo Health prices compounded injections.
If you want the FDA-approved brand rather than a compounded version, altRX is the only one of the two with a brand-name price.
Where each one treats patients
altRX lists 50 states, and Rylo Health lists 50 states.
They overlap in 50 states.
Pricing
altRX
Rylo Health
Standard rate $149/mo; quarterly $349. A First 20 promotional rate of $100/mo is advertised for the first 20 patients.
Standard rate $249/mo; quarterly $499. A First 20 promotional rate of $160/mo is advertised for the first 20 patients.
What each price covers
Both prices cover the clinician visit, the medication itself and shipping.
altRX is silent on lab work and coaching.
Rylo Health is silent on lab work and coaching.
altRX
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
Rylo Health
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
Where each one scores higher
Overall, Rylo Health scores 8.2 and altRX 7.6 out of 10.
Rylo Health is stronger on value (6.6 vs 5.0) and trust & safety (7.5 vs 6.0).
Effectiveness, user experience, accessibility and support are within half a point.
altRX
7.6/10
Rylo Health
8.2/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
FDA warning letters
The FDA sent altRX a warning letter dated June 8, 2026 (letter 728236), and it is still open.
Rylo Health has no FDA warning letter on record with us.
Features & Coverage
| Feature | altRX | Rylo Health |
|---|---|---|
| Starting Price | $149/mo | $149/mo |
| Features | ✓8 features | 4 features |
| States Available | 50 | 50 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | ✓ Yes | — |
| FSA/HSA Accepted | — | — |
| FDA Warning Letters | 1 letter | ✓None |
About altRX
Compounded plans open at $149 for semaglutide and $249 for tirzepatide. Branded medication runs $1,149-$1,579, a figure that already contains the consult and the shipping. Every one of the four FDA-approved brands is stocked, Mounjaro, Ozempic, Wegovy and Zepbound, which no other entry in our directory matches. altRX works in both modalities, holds LegitScript certification, and prints the FDA compounded-medication disclaimer.
Read our full altRX review →About Rylo Health
Compounded semaglutide and tirzepatide plus a peptide line, prescribed through Texas prescribers. Both the medical group and the dispensing pharmacy are named.
Read our full Rylo Health review →Pros & Cons
altRX
What we like
- Tirzepatide costs $1249 a month, close to the $1249 median for brand-name tirzepatide across the sellers we compare
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- The monthly price includes the medication, clinician visits and shipping
- Serves all 50 states
- Names 4 pharmacies that fill its prescriptions, which most sellers do not
Watch-outs
- Semaglutide costs $1149 a month, 15% above the $997 median for brand-name semaglutide across the sellers we compare
- The FDA has issued altRX a warning letter. Read what it alleges: a letter flags a problem but does not by itself rule a seller out
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Rylo Health
What we like
- Semaglutide costs $149 a month, 19% below the $185 median for compounded semaglutide across the sellers we compare
- Tirzepatide costs $249 a month, close to the $250 median for compounded tirzepatide across the sellers we compare
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- The monthly price stays the same as your dose goes up
- The monthly price includes the medication, clinician visits and shipping
- Serves all 50 states
- We found no FDA warning letters issued to Rylo Health
Watch-outs
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Our Verdict
Rylo Health wins this one, 8.2 to 7.6, above all for coverage in all 50 states, which most sellers will not confirm. altRX fits better if semaglutide from $1149/month is your priority.
Choose altRX if…
You want semaglutide from $1149/month and an opening price near $149 a month.
Choose Rylo Health if…
You want coverage in all 50 states, which most sellers will not confirm and an opening price near $149 a month.
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ShedRx
Oral orforglipron alongside the injectables
From $149/mo
Get started →bmiMD
Starting below a standard dose, with microdose tiers
From $99/mo
Get started →RxSpan MD
Knowing which pharmacy fills the vial: it names Belmar Pharmacy
From $249/mo
Get started →altRX vs Rylo Health: FAQ
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Novo Nordisk A/S owns the Wegovy®, Ozempic® and Rybelsus® marks; Eli Lilly and Company owns Mounjaro® and Zepbound®. Every other product name and mark on this page belongs to whoever owns it. No pharmaceutical manufacturer is affiliated with GLP Watchdog. See trademark disclaimer.