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Rylo Health vs Trinity Meds

Rylo Health and Trinity Meds both sell semaglutide and tirzepatide; this is how their prices, coverage and records differ.

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By Ruth Calder · Enforcement Editor
Editorially reviewed (not clinically reviewed). Not medical advice · How we verify contentLast reviewed
Rylo Health logo

Rylo Health

8.2
★★★★☆4.1/5

Best for: coverage in all 50 states, which most sellers will not confirm

Visit Rylo Health →
VS
Trinity Meds logo

Trinity Meds

8.4
★★★★☆4.2/5

Best for: compounded semaglutide at $149/month

Visit Trinity Meds →

If you are choosing between Rylo Health and Trinity Meds, price alone will not settle it. Both prescribe semaglutide and tirzepatide, so moving from one to the other would not change your drug. Trinity Meds leads our six-part score, 8.4 to 8.2.

Rylo Health vs Trinity Meds price

Rylo Health and Trinity Meds start at the same figure, $149 a month, so the entry price does not separate them. Look at what each price covers and at the per-drug prices below.

Drug by drug: Semaglutide costs the same at both, $149 a month; tirzepatide is cheaper at Trinity Meds ($199 a month vs $249 a month).

Medications and formats

Both sell semaglutide and tirzepatide.

On format they match: each offers compounded injections.

Where each one treats patients

Rylo Health lists 50 states, and Trinity Meds lists 50 states.

They overlap in 50 states.

Pricing

Rylo Health

Semaglutide, monthly (standard rate)Compounded
$149/mo
semaglutide

Standard rate $149/mo; quarterly $349. A First 20 promotional rate of $100/mo is advertised for the first 20 patients.

Tirzepatide, monthly (standard rate)Compounded
$249/mo
tirzepatide

Standard rate $249/mo; quarterly $499. A First 20 promotional rate of $160/mo is advertised for the first 20 patients.

Trinity Meds

Injectablecompounded injection
$149/mo
semaglutide

All-inclusive flat rate, same price every dose; as low as $129/mo on the 6-month plan

Injectablecompounded injection
$199/mo
tirzepatide

All-inclusive flat rate (reg $299); as low as $149/mo on the 12-month plan

What each price covers

Both prices cover the clinician visit, the medication itself and shipping.

Rylo Health is silent on lab work and coaching.

Trinity Meds is silent on lab work and coaching.

Rylo Health

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Not stated

Coaching

Not stated

Trinity Meds

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Not stated

Coaching

Not stated

Where each one scores higher

Overall, Trinity Meds scores 8.4 and Rylo Health 8.2 out of 10.

Trinity Meds is stronger on trust & safety (9.0 vs 7.5).

Value, effectiveness, user experience, accessibility and support are within half a point.

How we score

Rylo Health

8.2/10

Overall

Trinity Meds

8.4/10

Value25%

6.6A
vs
B
6.6

Effectiveness25%

10.0A
vs
B
10.0

User Experience15%

8.0A
vs
B
8.0

Trust & Safety15%

7.5A
vs
B
9.0

Accessibility10%

10.0A
vs
B
10.0

Support10%

7.0A
vs
B
7.0

FDA warning letters

Neither Rylo Health nor Trinity Meds has an FDA warning letter on record with us.

Features & Coverage

FeatureRylo HealthTrinity Meds
Starting Price$149/mo$149/mo
Features4 features✓6 features
States Available5050
Compounded✓ Yes—
Brand Name——
FSA/HSA Accepted—✓ Yes
FDA Warning LettersNoneNone

About Rylo Health

Compounded semaglutide and tirzepatide plus a peptide line, prescribed through Texas prescribers. Both the medical group and the dispensing pharmacy are named.

Read our full Rylo Health review →

About Trinity Meds

Trinity Meds charges an all-inclusive flat rate of $149/month for compounded semaglutide and $199/month for tirzepatide, the same price at every dose, with free shipping and no insurance; multi-month plans drop the price further. The program is aimed at military women, spouses and veterans. You take a short online assessment and a CareValidate Health clinician reviews eligibility and prescribes if appropriate. The named entity is Trinity Meds Inc, but it publishes no terms page, names no pharmacies, and lists no states.

Read our full Trinity Meds review →

Pros & Cons

Rylo Health

What we like

  • Semaglutide costs $149 a month, 19% below the $185 median for compounded semaglutide across the sellers we compare
  • Tirzepatide costs $249 a month, close to the $250 median for compounded tirzepatide across the sellers we compare
  • Shows its price before the medical questionnaire, so you can compare it without handing over health information
  • The monthly price stays the same as your dose goes up
  • The monthly price includes the medication, clinician visits and shipping
  • Serves all 50 states
  • We found no FDA warning letters issued to Rylo Health

Watch-outs

  • Ask which pharmacy fills the prescription before you pay, so you can check its license
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

Trinity Meds

What we like

  • Semaglutide costs $149 a month, 19% below the $185 median for compounded semaglutide across the sellers we compare
  • Tirzepatide costs $199 a month, 20% below the $250 median for compounded tirzepatide across the sellers we compare
  • Shows its price before the medical questionnaire, so you can compare it without handing over health information
  • The monthly price includes the medication, clinician visits and shipping
  • Serves all 50 states
  • Names 4 pharmacies that fill its prescriptions, which most sellers do not
  • We found no FDA warning letters issued to Trinity Meds

Watch-outs

  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

Our Verdict

Winner: Trinity Meds

Trinity Meds wins this one, 8.4 to 8.2, above all for compounded semaglutide at $149/month. Rylo Health fits better if coverage in all 50 states, which most sellers will not confirm is your priority.

Choose Rylo Health if…

You want coverage in all 50 states, which most sellers will not confirm and an opening price near $149 a month.

Choose Trinity Meds if…

You want compounded semaglutide at $149/month and an opening price near $149 a month.

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Rylo Health vs Trinity Meds: FAQ

Neither on the entry price: Rylo Health and Trinity Meds both start at about $149 a month. The difference is in what the price includes.
Yes, both sell semaglutide and tirzepatide.
Both list 50 states and share 50.
Both include the clinician visit, the medication itself and shipping.
Rylo Health has none. Trinity Meds has none.
No. Neither Rylo Health nor Trinity Meds pays us anything.

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