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Defy Medical Review

GLP-1 weight-loss telehealth · Independently scored 4.1/10

4.1
★★☆☆☆2.1/5

Defy Medical falls below our bar on disclosure. Read the breakdown below before you give it money.

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Covered by the plan

Medication

Not stated

Clinician visits

Not stated

Shipping

Not stated

Lab work

Not stated

Coaching

Not stated

Compare top-rated alternatives ↓

Neither a price nor a list of covered states appears online. Hormone replacement made Defy Medical's name over many years, but the clinic writes GLP-1s too: semaglutide and tirzepatide as weekly shots, as orally disintegrating tablets and as liquid drops, with liraglutide taken daily by injection. Those drops and ODTs exist for patients who will not self-inject, or who live where shipping an injectable is restricted. Consults go deep, blood testing is comprehensive, and phlebotomy can come to you. Dr. Justin Saya is medical director.

By Ruth Calder · Enforcement Editor
Editorially reviewed (not clinically reviewed). Not medical advice · How we verify contentLast reviewed
Price after intakeNo FDA warning letters found

Is Defy Medical legit?

Yes. Defy Medical is a real, operating US company, and we found no FDA warning letters issued to it. We rate it 4.1/10 overall, across six areas from price to trust and safety. Legitimate is not the same as right for you, though: that part is a decision for you and a licensed clinician.

Is there a Defy Medical promo or coupon code?

We know of no promo or coupon code for Defy Medical. Coupon sites advertising "Defy Medical discount codes" are not a source we can vouch for, and any genuine offer shows at checkout without a code.

See how Defy Medical compares on our rankings of the best weight-loss injection providers.

Vetted alternatives to Defy Medical

9.4/ 10
Verified partner

Trimi Health

Best for: knowing which pharmacy fills the vial: it names VialsRx

★★★★★4.7/5

Editorial score · methodology

$99/mo
CompoundedSemaglutideTirzepatide
Get StartedRead full Trimi Health review →
6.4/ 10
Verified partner

ShedRx

Best for: oral orforglipron alongside the injectables

★★★☆☆3.2/5

Editorial score · methodology

$149/mo
CompoundedSemaglutideTirzepatideOrforglipronGHK-Cu
Get StartedRead full ShedRx review →
9.0/ 10
Verified partner

bmiMD

Best for: starting below a standard dose, with microdose tiers

★★★★★4.5/5

Editorial score · methodology

$99/mo
CompoundedSemaglutideTirzepatideGlutathioneNAD+
Get StartedRead full bmiMD review →
Defy Medical logo
2.1 / 5
Our editorial rating
Visit Defy Medical →

Defy Medical at a glance

Type
GLP-1 telehealth provider
Medications
Semaglutide injection, Tirzepatide injection, Liraglutide option
FDA status
No FDA warning letters found

How Defy Medical scores

Six columns, each one computed from something Defy Medical has published rather than from an opinion we formed: what it charges, which molecules it will dispense, what its record shows, and what the monthly figure actually buys. Where a seller keeps something back, such as its price or its pharmacy, the score reflects it. Every seller we review goes through the same six columns.

Value25%

3.0/10

There is no monthly price to compare, so Value is capped rather than scored against other sellers.

Effectiveness25%

5.0/10

No medication list or price is available to score, so this is held at the midpoint. It is not a judgment on the drugs themselves.

User Experience15%

3.0/10

No price appears until the medical intake is finished.

Trust & Safety15%

4.0/10

No pharmacy is named for its prescriptions. Its price appears only after the medical intake.

Accessibility10%

5.0/10

No state list is available to check, so this is held at the midpoint rather than scored on reach.

Support10%

5.0/10

No published price, so what a price would include cannot be assessed. Held at the midpoint.

6weighted dimensions
588sellers compared
Everychecked against the seller's own site
Value 25%Effectiveness 25%User Experience 15%Trust & Safety 15%Accessibility 10%Support 10%

A seller that shows no price until after the medical intake loses points on User Experience and Trust & Safety, and its review says so. How we score →

What we checked on Defy Medical

Last checked August 2026
  • Checked FDA warning letters for Defy Medical

Price, availability, and compliance here are read off the seller's own pages and off primary regulatory records, named in the sources below.

What signing up with Defy Medical involves

What to expect on the way to a prescription: where the price appears, who fills the medication, and what the monthly price covers. It is not medical advice, and a clinician makes the prescribing decision.

  1. 1Defy Medical shows a price only after you finish its medical questionnaire, so you cannot compare costs until you have shared health information.
  2. 2Ask Defy Medical which pharmacy fills the prescription before you pay. The pharmacy's name is what lets you check its license.
Price shown only after intake
  • Before you commit, get the ongoing monthly price of the medication itself, not a first-month rate, a membership fee or a per-vial price.
  • Confirm that Defy Medical serves your state before you start.

Contacting Defy Medical

Hours
Mon-Fri 8:00 AM-7:00 PM EST; Sat 9:00 AM-2:00 PM EST

GLP-1 medications Defy Medical offers

Each one has its own guide: how the molecule works, the dosing schedule, the side effects that show up in practice, and what the trials actually measured.

In its favor

  • We found no FDA warning letters issued to Defy Medical

Against it

  • You only see a price after finishing the medical intake, so you cannot compare costs before sharing health information
  • Confirm it serves your state before you start the intake
  • Ask which pharmacy fills the prescription before you pay, so you can check its license

What Defy Medical charges

There is no standard monthly price to quote for Defy Medical, so you cannot compare it with other sellers until you have been through an intake and received a quote. When you get one, ask for the ongoing monthly figure and what it includes, not the first-month rate and not a program total divided by its length.

What Defy Medical dispenses

Defy Medical prescribes semaglutide (approved as Wegovy and Ozempic) and tirzepatide (approved as Zepbound and Mounjaro). Between them these are the two best-evidenced weight-loss molecules currently on the market.

A needle-free oral option is genuinely uncommon and is the reason some readers will look at Defy Medical at all. Set expectations on the evidence, though: the published weight-loss trials for these molecules used injections. Oral and sublingual delivery of peptides is far less studied, so treat it as a route that solves the needle problem rather than as a proven equal to the shot.

Safety and disclosure

Before you start an intake, ask Defy Medical which states it serves, which pharmacy fills its prescriptions and what the monthly price includes. We found no FDA warning letters issued to Defy Medical. How we weigh oversight, disclosure and price is set out in our scoring methodology.

Who should look elsewhere

  • You want to compare prices before spending time on an intake. There is no standard monthly price to compare.
  • You need insurance to cover the cost. Check whether Defy Medical bills your plan before you start.

It fits if

  • injections are the thing keeping you from starting

Our read

Whether Defy Medical is priced well is impossible to judge before an intake, because there is no standard price to compare. That does not rule it out, and plenty of legitimate sellers quote after intake, but it puts the comparison after you have spent the time, which is the wrong order for you as the buyer. Collective is the nearest comparison we review, and worth reading alongside this.

The Bottom Line

Defy Medical falls below our bar on disclosure. Read the breakdown below before you give it money.

Score: 4.1/10

Before you pay Defy Medical

Check today's price, then start the intake.

Where Defy Medical is the wrong choice

No seller suits every reader, and pretending otherwise is the easiest way to sell one. On these two counts, another seller does better.

  • If you need the FDA-approved pen rather than a compounded vial, consider Sesame Care.
  • If you want a human checking in, not just a prescription, consider ShedRx.

Compare Defy Medical head to head

The sellers closest to Defy Medical on medication and price.

Frequently Asked Questions

Neither a price nor a list of covered states appears online. Hormone replacement made Defy Medical's name over many years, but the clinic writes GLP-1s too: semaglutide and tirzepatide as weekly shots, as orally disintegrating tablets and as liquid drops, with liraglutide taken daily by injection. Those drops and ODTs exist for patients who will not self-inject, or who live where shipping an injectable is restricted. Consults go deep, blood testing is comprehensive, and phlebotomy can come to you. Dr. Justin Saya is medical director. We rate it 4.1/10 overall.
There is no standard monthly cash price to quote for Defy Medical, so you cannot compare it with other sellers until you have been through its intake. If you go ahead, ask for the ongoing monthly rate, not just the first month.
Ask Defy Medical whether it serves your state before you start the intake, and get the answer in writing.
Defy Medical sells semaglutide (sold as Wegovy and Ozempic) and tirzepatide (sold as Zepbound and Mounjaro). A needle-free oral form is listed as well.
Check whether Defy Medical bills your insurance before you sign up.
You fill in an online intake, a licensed clinician decides whether a GLP-1 is appropriate, and if the answer is yes the medication ships to you. Defy Medical runs that whole sequence on its own site.
We found no FDA warning letters issued to Defy Medical. Before you buy, weigh these: You only see a price after finishing the medical intake, so you cannot compare costs before sharing health information. Confirm it serves your state before you start the intake. Ask which pharmacy fills the prescription before you pay, so you can check its license. None of them rules Defy Medical out, but each is worth settling before you pay.

Glossary

The words sellers use, defined. Tap any term.

Sources

Cited across this Defy Medical review: primary regulatory filings, and peer-reviewed studies.

Sources & methodology — as of August 2026
  1. 1.GLP Watchdog — GLP-1 Pricing Index 2026 (our independent dataset)— GLP Watchdog.
  2. 2.FDA — Compounding and the 503A Pharmacy Framework— U.S. Food & Drug Administration.
  3. 3.FDA — Drug Shortages Database (current shortage listings)— U.S. Food & Drug Administration.
  4. 4.PCAB — Pharmacy Compounding Accreditation Board Standards— Accreditation Commission for Health Care (ACHC) / PCAB.
  5. 5.KFF — Medicaid coverage research (anti-obesity & GLP-1 drug policy)— Kaiser Family Foundation.

See Defy Medical's current pricing

Whether you qualify is a clinician's decision, made after your intake.