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Defy Medical Review

GLP-1 weight-loss telehealth · Independently scored 4.1/10

4.1
★★☆☆☆2.1/5

Defy Medical falls below our bar on medical oversight. Read the breakdown below before you give it money.

Covered by the plan

Medication

Not stated

Clinician visits

Not stated

Shipping

Not stated

Lab work

Not stated

Coaching

Not stated

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No insurance neededVetted by our editors

Compare top-rated alternatives ↓

Neither a price nor a list of covered states appears online. Hormone replacement made Defy Medical's name over many years, but the clinic writes GLP-1s too: semaglutide and tirzepatide as weekly shots, as orally disintegrating tablets and as liquid drops, with liraglutide taken daily by injection. Those drops and ODTs exist for patients who will not self-inject, or who live where shipping an injectable is restricted. Consults go deep, blood testing is comprehensive, and phlebotomy can come to you. Dr. Justin Saya is medical director.

By Ruth Calder · Enforcement Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Price after intakeNo FDA letter on record

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★★★★4/5

Editorial score · methodology

$119/mo
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Editorial score · methodology

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Found

Best for: tirzepatide at $169/month, 37% under the register median

★★★★4.4/5

Editorial score · methodology

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Defy Medical logo
2.1 / 5
Our editorial rating
Visit Defy Medical

Defy Medical at a glance

Type
GLP-1 telehealth provider
Medications
Semaglutide injection, Tirzepatide injection, Liraglutide option
FDA status
No FDA warning letter on record

How Defy Medical scores

Six columns, each one computed from something Defy Medical has published rather than from an opinion we formed: what it charges, which molecules it will dispense, what its record shows, and what the monthly figure actually buys. Where it publishes nothing, that absence is what gets scored. Every seller in the register goes through the same six columns.

Value25%

3.0/10

No monthly price is published at all, so value cannot be measured against the register. Capped rather than scored.

Effectiveness25%

5.0/10

Publishes no medication list or price, so what is prescribed here cannot be established. Held at the midpoint — this is a gap in the record, not a finding about the drugs.

User Experience15%

3.0/10

On the seller's own pages, no price appears until the medical intake is finished.

Trust & Safety15%

4.0/10

does not name a dispensing pharmacy; withholds price until after the intake. Our verification confidence is medium.

Accessibility10%

5.0/10

Publishes no list of states served, so coverage cannot be confirmed either way. Capped at the midpoint — this measures disclosure, not reach.

Support10%

5.0/10

No published price, so what a price would include cannot be assessed. Held at the midpoint.

6weighted dimensions
560sellers in the register
Everychecked against the seller's own site
Value 25%Effectiveness 25%User Experience 15%Trust & Safety 15%Accessibility 10%Support 10%

A seller that will not show a price before an intake loses points on Value and carries that note in its review. Withholding the number is itself a finding. How we score →

What we checked on Defy Medical

Last checked June 2026
  • Searched our FDA enforcement register for this operator

Price, availability, and compliance here are read off the seller's own pages and off primary regulatory records, named in the sources below. Editorial confidence in this data: medium.

What signing up with Defy Medical involves

Assembled from this seller’s entry in the register — the price record, the state list, the dispensing pharmacy where one is named, and what the monthly figure covers. It describes what a reader can expect to meet on the way to a prescription, and what is missing from the seller’s own disclosures. It is not a clinical judgment and not a prescribing decision.

  1. 1Defy Medical does not show a price until you have worked through its medical questionnaire. Budget for the fact that you cannot compare it against anything until you have handed over health information.
  2. 2The intake is a written questionnaire. No live video visit or baseline bloodwork is recorded as required.
  3. 3Defy Medical does not say which pharmacy dispenses the medication. That is common here and it means you cannot check the pharmacy's record before you buy.
Price shown only after intake
  • No comparable monthly cash price for the medication is on record — either nothing is published, or what is published is a fee, an insured copay or a per-vial rate rather than a monthly cost.
  • No state list is published, so whether Defy Medical serves your state cannot be confirmed from its site.

Defy Medical support, as documented

Hours
Mon-Fri 8:00 AM-7:00 PM EST; Sat 9:00 AM-2:00 PM EST

GLP-1 medications Defy Medical offers

Each one has its own guide: how the molecule works, the dosing schedule, the side effects that show up in practice, and what the trials actually measured.

In its favor

  • No FDA warning letter matched this operator when we searched our enforcement register

Against it

  • No price appears until the medical intake is complete, so the cost cannot be compared before health information is submitted
  • No state list is on record here, so whether it serves your state cannot be confirmed from this page
  • No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here

What Defy Medical charges

Defy Medical does not publish a standing monthly price. That is a choice, and it means you cannot compare it against anything until you have gone through an intake and been quoted. When you get that quote, ask specifically for the ongoing monthly figure and what it includes — not the first-month rate, and not a program total divided by its length.

What Defy Medical dispenses

Defy Medical prescribes semaglutide (approved as Wegovy and Ozempic) and tirzepatide (approved as Zepbound and Mounjaro). Between them these are the two best-evidenced weight-loss molecules currently on the market.

A needle-free oral option is genuinely uncommon and is the reason some readers will look at Defy Medical at all. Set expectations on the evidence, though: the published weight-loss trials for these molecules used injections. Oral and sublingual delivery of peptides is far less studied, so treat it as a route that solves the needle problem rather than as a demonstrated equal to the shot.

What we could verify

Defy Medical publishes little that can be checked from outside an intake. We searched the federal warning-letter record for this operator and came back with nothing. How we weigh oversight, disclosure and price evidence is set out in our scoring methodology.

Who should look elsewhere

  • You want the FDA-approved pen specifically. Nothing here is the approved finished product.
  • You need to compare prices before committing time to an intake — there is no published figure to compare.
  • You need to bill insurance. Like most of this market, this is cash-pay.

It fits if

  • injections are the thing keeping you from starting

Our read

We cannot tell you whether Defy Medical is priced well, because it does not say. That is not automatically disqualifying — plenty of legitimate operators quote after intake — but it does mean the comparison has to happen after you have spent the time, which is the wrong order for the buyer. CoreAge Rx is the nearest comparison we track, and worth reading alongside this.

The Bottom Line

Defy Medical falls below our bar on medical oversight. Read the breakdown below before you give it money.

Score: 4.1/10

Before you pay Defy Medical

Check today's price, then book the free consultation.

Where Defy Medical is the wrong choice

No seller in this register suits every reader, and saying otherwise would be the easiest way to sell one. On these four counts another entry does better.

  • If you need the FDA-approved pen rather than a compounded vial, consider Found.
  • If you want a human checking in, not just a prescription, consider Oak.

Frequently Asked Questions

Glossary

The words sellers use, defined. Tap any term.

Sources

Cited across this Defy Medical review: primary regulatory filings, and peer-reviewed studies.

Sources & methodology — as of August 2026
  1. 1.GLP Watchdog — GLP-1 Pricing Index 2026 (our independent dataset)GLP Watchdog.
  2. 2.FDA — Compounding and the 503A Pharmacy FrameworkU.S. Food & Drug Administration.
  3. 3.FDA — Drug Shortages Database (current shortage listings)U.S. Food & Drug Administration.
  4. 4.PCAB — Pharmacy Compounding Accreditation Board StandardsAccreditation Commission for Health Care (ACHC) / PCAB.
  5. 5.KFF — Medicaid coverage research (anti-obesity & GLP-1 drug policy)Kaiser Family Foundation.

See Defy Medical's current pricing

The free consultation is where you learn whether you qualify, and what it costs today.