Direct Meds vs Willow

Direct Meds has an open FDA warning letter dated September 9, 2025. Willow has none. On compounded semaglutide injection, Direct Meds costs $24 less a year at standing rates: $297 a month against $299 a month at Willow.

To see where both sit among the other sellers, read our best weight-loss injection providers board.

By Ruth Calder · Enforcement Editor
Editorially reviewed. Not medical advice · How we verify contentLast reviewed

The record

Direct Meds / Willow

Featured pick (affiliate partner)

Direct Meds logo

Direct Meds

7.1/10

Willow logo

Willow

7.3/10

FDA warning letters
None on record
Pharmacy
None named in our record
Lowest standing price
$249/moCompounded oral semaglutide
$299/moCompounded semaglutide injection
States
48 states and DC
35 states
Checked
Prices captured Record checked October 2026
Prices captured Record checked September 2026

Direct Meds is our featured pick on this page because it is an affiliate partner: we are paid if you sign up through our link. Willow pays us nothing. The scores are computed the same way for both and are shown as computed (Direct Meds 7.1, Willow 7.3). How we are paid

What the record shows

  1. 01

    Direct Meds has an open FDA warning letter dated September 9, 2025. Willow has none.

  2. 02

    Willow names five pharmacies. Direct Meds names no compounding pharmacy in our record.

  3. 03

    On compounded semaglutide injection, Direct Meds costs $24 less a year at standing rates: $297 a month against $299 a month at Willow.

  4. 04

    Only Direct Meds lists a price for compounded oral semaglutide and compounded oral tirzepatide.

  5. 05

    Direct Meds covers 13 states Willow does not.

  6. 06

    Direct Meds holds you to a 90-day supply shipped at once, remaining months billed every 30 days; Willow states you can cancel at any time.

Prices and terms, product by product

A price is set against the other side only for the same product, and only when both are standing monthly or 4-week rates. Those pairs are compared by yearly cost.

Direct Meds

Willow

Compounded semaglutide injection

$297/moLower

$3,564 a year

$299/mo

$3,588 a year

Compounded tirzepatide injection

$399/mo

$4,788 a year

$399/mo

$4,788 a year

Compounded oral semaglutide

$249/mo

$2,988 a year

Not sold or not priced
Compounded oral tirzepatide

$299/mo

$3,588 a year

Not sold or not priced
Price includes
Medication, clinician visits, shipping
Medication, clinician visits, shipping
Cancel any time
No
Yes, stated
Minimum term
90-day supply shipped at once, remaining months billed every 30 days
None
Refunds
No refunds for medication already received; $35 disposal fee on returns
Full refund if you cancel before the prescription is sent to the pharmacy; none once the medication is compounded

Read off each seller’s own pages. Direct Meds: October 17, 2026. Willow: July 10, 2026. Every plan and dose we hold is on the full review.

The case for each

The case for Direct Meds

7.1/10
Featured pick (affiliate partner)
  • $24 a year less on compounded semaglutide injection
  • Sells compounded oral semaglutide and compounded oral tirzepatide, which Willow does not price
  • Lists 48 states against 35
  • Open FDA warning letter, September 9, 2025
  • Names no compounding pharmacy
  • Minimum commitment before you can cancel

The case for Willow

7.3/10
  • No FDA warning letter on record
  • Names its compounding pharmacy
  • States you can cancel at any time

Scores

Direct Meds 7.1 · Willow 7.3 out of 10. Six weighted parts.

Value25%

4.2A
vs
B
3.0

Effectiveness25%

10.0A
vs
B
10.0

User Experience15%

8.0A
vs
B
8.0

Trust & Safety15%

4.5A
vs
B
9.0

Accessibility10%

9.7A
vs
B
7.6

Support10%

7.0A
vs
B
7.0

The score is the same formula for every seller. Payment does not enter it. Method

Direct Meds vs Willow: questions

Direct Meds has an open FDA warning letter dated September 9, 2025. Willow has none. Letters are matched to a seller by company, domain and address, never by a similar name.
Willow names five pharmacies. Direct Meds names no compounding pharmacy in our record. A 503A pharmacy compounds for named patients on a prescription; a 503B outsourcing facility is registered with FDA and inspected under federal manufacturing rules.
Direct Meds, by $24 a year at standing rates. Direct Meds: $297 a month, about $3,564 a year. Willow: $299 a month, about $3,588 a year.
Direct Meds has a minimum term (90-day supply shipped at once, remaining months billed every 30 days). Willow states you can cancel at any time; refunds: full refund if you cancel before the prescription is sent to the pharmacy; none once the medication is compounded.
Direct Meds is our featured pick on this page because it is an affiliate partner: we are paid if you sign up through our link. Willow pays us nothing. The scores are computed the same way for both and are shown as computed (Direct Meds 7.1, Willow 7.3).

Other sellers we are paid by

Affiliate partners outside this pair. Each has its own record and review, scored the same way.

Matched on molecule, form and price. Every pair we list · The register